Concor - duration of use in the treatment of diseases of the cardiovascular system

Beta-1 blockers are great for lowering blood pressure and improving the functioning of the cardiovascular system in general. A good drug in this segment is Concor.

The medicine helps stabilize blood pressure, and also has antiarrhythmic and antianginal effects (eliminates symptoms of coronary heart disease).

The medication is available in the form of tablets for oral use. There are tablets with 2.5 mg, 5 mg and 10 mg of the active ingredient. The price of the medicine in the pharmacy is about 150-400 rubles for a package of 30 tablets (the cost depends on the amount of active ingredient in the tablet).

Release form

Concor tablets are coated with a light orange shell, heart-shaped, biconvex, with serifs on both edges.

Release forms for Concor (dosage 5 and 10 mg):

• ten such tablets in a blister, five or three such blisters in a cardboard package;
• or 25 such tablets in a blister, two such blisters in a cardboard package;
• or 30 such tablets in a blister, one such blister in a cardboard package.

For Concor 10 mg there is additionally the following release form:

• 30 tablets in a blister, three such blisters in a cardboard package.

The effect of "Anaprilin" on heart rhythm

The active ingredient of the drug "Anaprilin" is propranolol.
Has a hypotensive effect, reduces blood pressure. It has an antiarrhythmic effect due to a direct effect on beta-adrenergic receptors of the first and second types in the heart muscle, bronchi, and blood vessels. Under the influence of propranolol, the influence of the sympathetic nervous system on the heart weakens, which is manifested by a decrease in the frequency and strength of contractions. Due to the membrane-stabilizing effect, the drug has an antihypoxic effect and reduces the myocardial oxygen demand. The hypotensive effect is observed later than the antiarrhythmic effect. First of all, the drug affects cardiac activity, restoring sinus rhythm and eliminating tachyarrhythmia.

Propranolol is produced in tablet form at 10, 20, 40, 60 and 80 mg, or in ampoules for injection. The dosage of "Anaprilin" for tachycardia ranges from 0.01 (10 mg) to 40 mg, with a maximum daily dose of 300 mg, divided into 3-6 doses. The elimination period of Propranolol reaches 3-6 hours, with long-term treatment 12 hours, which is taken into account when calculating the frequency of administration against the background of arrhythmia. To prevent overdose, you should follow the instructions after receiving the recommendations of a cardiologist or therapist.

Rules of use for tachycardia

Tachyarrhythmia is a violation of sinus rhythm with an increase in frequency above 90 beats per minute. The active substance propranolol hydrochloride affects the strength of myocardial excitability, reduces activity in the sinus node, which helps restore heart rate. Thus, “Anaprilin” reduces the pulse and normalizes heart rate. However, in case of an overdose of the drug, bradycardia, a pronounced slowdown in heart rate of less than 45 beats per minute, may develop.

Under the influence of the drug, the conduction of impulses slows down, the activity of foci of excitation that cause pathological tachycardia decreases, and therefore “Anaprilin” is used to treat cardiac arrhythmias. Indicated for:

• sinus tachycardia;
• rhythm disturbances due to VSD, menopause, hyperthyroidism;
• supraventricular arrhythmia;
• tachysystolic variant of fibrillation;
• paroxysmal atrial fibrillation;
• extrasystoles emanating from the ventricles, atria;
• sympathoadrenal crisis with concomitant pathology.

The principle of action of beta blockers using the example of Concor

The antiarrhythmic drug Bisoprolol also has a hypotensive and antianginal effect. It is produced in dosages of 5 and 10 mg. It affects the first type of beta-blockers in the human heart muscle and bronchi, due to which it is selective, does not affect the contractility of peripheral vessels and does not have a sympathomimetic effect. This reduces the risk of developing bradycardia and arterial spasm when taken.

When taking Bisoprolol, blood pressure decreases and oxygen saturation of the body improves. As a result of a selective effect on the beta receptors of the heart, the frequency of contractions is reduced, the conduction of electrical impulses slows down, and the rhythm is restored. The drug is effective for stopping sinus tachycardia, treating patients with hypertension, coronary artery disease and angina attacks.

An exception to taking Bisoprolol is severe cardiovascular pathology, decompensated heart failure and 2-3 degree blockades.

Features of the use of "Concor" for tachycardia

The highly selective drug "Concor" is prescribed for tachycardia, coronary artery disease and failure with dysfunction of the left ventricle of the heart.
This is an original and registered German medicine, available in tablets of 2.5, 5 and 10 mg. The active ingredient is bisoprolol, a selective beta-1 blocker. This means that the drug has a blocking effect exclusively on the first type of receptors in the myocardium of the heart and in the kidneys, due to which it begins to act quickly and exhibits the necessary antiarrhythmic and antianginal effect. "Concor" does not act on beta-2 receptors of the bronchi and vascular walls, which reduces the risk of side effects, bronchial spasm, and cough when taking the medicine. However, it affects the receptors of the aorta and carotid sinus, and this is manifested by a decrease in blood output and a hypotensive effect. Under the influence of Concor, the pulse decreases, its frequency, the strength of heart contractions, and blood flow are normalized. With long-term use, it significantly improves the well-being of patients with coronary artery disease.

Taking Bisoprolol, Concor or Anaprilin for arrhythmia and tachycardia during pregnancy is permitted only after consultation with the attending physician, taking into account the possible risks for the mother and fetus.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

The drug Concor is a selective beta-1 adrenergic blocker , without sympathomimetic action. This honey preparation also does not have a membrane-stabilizing effect.

The use of the drug Concor does not affect the condition of the respiratory tract and metabolic processes in which beta-2 adrenergic receptors .

INN (international nonproprietary name) of the drug: “bisoprolol”.

Does not have a strong negative inotropic effect. Reduces the tone of the sympathoadrenal system , suppresses beta-1 adrenergic receptors of the heart.

When taken once in patients with coronary heart disease without chronic heart failure, bisoprolol reduces the number of heart contractions, stroke volume, ejection fraction and myocardial oxygen demand. With long-term therapy, the increased total peripheral vascular resistance decreases.

The maximum effect occurs three hours after administration. When bisoprolol once a day, its effect lasts 24 hours. The maximum decrease in pressure is recorded 12-14 days after the start of therapy.

Pharmacokinetics

Bisoprolol is absorbed from the intestine by 90%. Bioavailability – 90%. Eating does not affect bioavailability. Concentrations of bisoprolol in blood plasma are proportional to doses taken in the range of 5-20 mg. The highest concentration in the blood occurs at 3 hours.

Plasma protein binding approaches 30%. All derivatives are excreted by the kidneys and are pharmacologically inactive. The half-life is 11-12 hours.

How does the drug work?

Arterial hypertension is the most common pathology of the cardiovascular system. Unfortunately, it is impossible to cure the disease, but it is quite possible to stabilize the patient’s condition.

For this purpose, medications with a pronounced hypotensive effect are used. Beta-1 blockers are widely used. One of the most effective drugs in this segment is Concor.

Doctors are often asked the question, does Concor lower blood pressure or not? Of course, it reduces, because the medication has a pronounced hypotensive effect. Patients also have a question: Does Concor reduce blood pressure or just pulse? The drug has a pronounced antiarrhythmic, antianginal and hypotensive effect, so when taking the tablets, both blood pressure and pulse are stabilized.

Let's consider the principle of action of the medication. So, it includes:

1. The active components are bisoprolol hemifumarate and bisoprolol fumarate (ratio 2:1).
2. Excipients: crospovidone, magnesium stearate, microcrystalline cellulose, silicon dioxide, calcium hydrogen phosphate, corn starch.
3. The composition of the shell is hypromellose, yellow iron oxide, dimethicone, macrogol 400, titanium dioxide.

The active components reduce the activity of the sympathoadrenal system by blocking beta-1 adrenergic receptors of the heart. The substance has a hypotensive effect by reducing cardiac output and inhibiting the secretion of rhinin. In addition, the active components affect the baroreceptors of the carotid sinus and aorta.

The advantage of the drug is the fact that its active components have low affinity for beta-2 receptors of the smooth muscle structure of the bronchi, blood vessels and endocrine system. Due to this, when using the medicine, it is possible to avoid effects on glucose metabolism, bronchi and peripheral arteries. Long-term use of Concor helps reduce increased peripheral vascular resistance.

Contraindications

Contraindications to the use of Concor:

• acute form of heart failure;
• decompensated chronic heart failure;
• AV blockade 2-3 degrees;
• cardiogenic shock;
• sinoatrial block;
• bradycardia;
• pronounced decrease in pressure;
• bronchial asthma and COPD;
• metabolic acidosis;
• severe changes in peripheral arterial circulation;
• pheochromocytoma;
• age less than 18 years;
• allergy to the components of the drug.

Indications and contraindications for use

Concor has indications for use similar to bisoprolol - arterial hypertension, tachycardia, chronic heart failure, angina pectoris. Taking Concor is contraindicated in the following cases:

• Acute heart failure;
• CHF in the decompensated stage, in which it is necessary to use drugs with a positive inotropic effect;
• The presence of 2-3 degree AV blockade without a pacemaker, as well as sinoatrial blockade;
• Severe hypotension;
• Pathologies of blood microcirculation, in particular Raynaud's syndrome;
• Decrease in heart rate less than 60 beats/s;
• The presence of individual intolerance to Concor components or allergic reactions;
• The presence of pathologies of the respiratory system of the obstructive type, including those with previous diseases;
• Age less than 18 years.

It is recommended to use the drug with caution in the presence of Prinzmetal's angina, an excessively enlarged thyroid gland, congenital heart defects, psoriasis, renal and hepatic pathologies (in particular, acute failure), and a myocardial infarction suffered earlier than 3 months ago. It is not recommended to use the drug during pregnancy and breastfeeding.

Similar recommendations apply to people who have diabetes or have significant fluctuations in their blood sugar levels. In the above cases, the drug should be taken only as prescribed by a doctor, subject to the use of alpha and beta blockers.

In the vast majority of cases, people leave only positive reviews about using Concor. The medicine is very effective and copes well with both tachycardia and other associated pathologies. Information on irecommend and otzovik indicates that the medicine is of great help to both older and younger people.

We suggest you read: Causes of increased red blood cells in the blood of a teenager. Red blood cells in a child are elevated - causes and symptoms

The only drawback noted by all users who have taken the drug is the large number of side effects. Note that in practice, side effects are possible only in cases of unsystematic or incorrect use of the drug. Parallel use of the drug with other medications is also important.

Reduces heart rate.

Side effects.

"Concor Cor" is a selective beta-blocker.

It has a heart-shaped, white, biconvex film-coated tablet with a score line on both sides.

From time to time, attacks of heartbeat (tachycardia) appear, and in this case you have to resort to medications if you also have a high pulse.

"Concor Cor" - began to be taken as prescribed by a doctor, and this drug should be strictly followed under the supervision of a doctor - in order to avoid the opposite effect in the form of angina pectoris (side effects).

If the pulse is high with normal pressure, then not only the heartbeat may decrease, but also the blood pressure, so in this case hypotension and bradycardia are possible, so Concor Cor should be taken with caution.

“Concor-cor” itself took several days, in a course regimen for 10 days, after a few days I noticed an improvement, the heartbeat really decreased, but on the other hand, with constant use, side effects appear in the form of low blood pressure and bradycardia.

If “Concor-cor” is taken for a long time, that is, constantly, then you should NEVER quit abruptly in order to avoid withdrawal syndrome and worse results.

To avoid withdrawal symptoms and worse results, the drug should be stopped gradually, reducing the dose of the medication, but not sharply.

Be healthy!

Time of use: 2 courses.

General impression. By the way, for tachycardia.

Arrhythmia is a fairly common heart disease in which the heart rate is abnormal. A person suffering from arrhythmia feels a sinking heart or, conversely, an increase in the frequency of its beats. Medicines for cardiac arrhythmia are prescribed only by a doctor. You must first undergo examinations such as ECD, Holter monitoring and others. Which medications you can take depends on the type of arrhythmia.

Medicines for tachycardia

With tachycardia, the heart rate is above 90 beats per minute.

1. In this case, hawthorn, elecampane, and valerian tincture are prescribed. Corvalol for cardiac arrhythmia quite effectively helps reduce the heart rate.

2. In especially severe cases, it is recommended to take drugs such as verapamil, lidocaine, digoxin, etmozin, propranolol, rhythmilene. It is forbidden to take strong drugs on your own. They must certainly be prescribed by the attending physician after the examination.

3. Tea with lemon balm, infusion of hawthorn flowers and motherwort herbs are suitable as folk remedies for the treatment of tachycardia.

Medicines for bradycardia

With this disease, there is a slowing of the heart rate. The heart beats at a frequency of no more than 60 beats per minute.

1. You can speed up the work of the heart with the help of medications such as atropine, atenolol, aminophylline, alupent. They cannot be taken on their own. All of the drugs listed are quite potent and, if taken incorrectly, can cause harm to the body.

2. You can speed up the work of the heart with the help of folk remedies. In this case, decoctions of yarrow and young tops of pine branches are suitable for the treatment of bradycardia. It is also recommended to eat a lot of nuts and a mixture of lemon and garlic.

Medicines for atrial fibrillation

Atrial fibrillation is characterized by chaotic contractions of both atria.

1. Allapinin for arrhythmias helps normalize heart function. You can also take amiodarone, disopyramide, sotalol, etacizine, quinidine, propafenone. In addition, Concor is taken for arrhythmia. This drug has a long shelf life, but is expensive. As a cheaper analogue, you can use bis-sagamma.

2. Folk remedies for atrial fibrillation can be taken without fear. The following will help to cope with an attack: hawthorn tincture, valerian rhizomes, trifoliate, peppermint collection, calendula flower tincture, eleutherococcus extract.

Medicines for extrasystole

Extrasystole refers to premature contractions of the heart.

1. You can fight this heart disease by taking the following medications: oxprenolol, pindolol, atenalol, propranolol, metoprolol, sotalol, amiodarone, talinolol. Medications are prescribed only by a doctor.

2. For those who prefer traditional medicine, this disease can be treated with infusions of valerian, calendula flowers, cornflower, lemon balm and horsetail. In addition, you can take hawthorn for arrhythmia and decoctions of adonis, rosehip seeds, and valerian.

The drug "Concor" is recommended to be taken in therapy:

• arterial hypertension (hypertension);
• for ischemic heart disease with the prevention and relief of angina attacks;
• chronic cardiac dysfunction.

Contraindications to the use of this medication are:

• individual intolerance to bisoprolol or other components of the drug;
• acute heart failure;
• pheochromocytoma;
• metabolic acidosis;
• severe bronchial asthma;
• low blood pressure, bradycardia;
• various disturbances in the passage of impulses through the heart;
• cardiogenic shock;
• organ circulatory disorders;
• Raynaud's disease.

Side effects of Concor

Reviews of side effects are not uncommon; the most commonly reported are slow heartbeat, hypotension, nausea and poor health.

• From the circulatory system: bradycardia , worsening of chronic heart failure , numbness of the extremities, severe decrease in blood pressure, orthostatic hypotension .
• From the nervous system and psyche: dizziness, loss of consciousness, headache, depression , insomnia , nightmares.
• From the respiratory system: attack of bronchial asthma .
• From the musculoskeletal system: cramps , muscle weakness.
• From the senses: hearing damage, conjunctivitis .
• From the digestive system: diarrhea , nausea, vomiting, increased levels of AST and ALT in the blood.
• From the genitourinary system: potency disorders.
• Skin: alopecia .
• Allergic reactions: itching, rash, redness of the skin, allergic rhinitis .

Review of drugs for the treatment of tachycardia

Many expectant mothers are interested in the question: is it possible to take Concor during pregnancy? And this is not surprising, because during this period a woman should take her health as seriously as possible. Before starting any medications, she needs to see a doctor who will assess the balance of benefits and harms from such treatment. This rule also applies to the drug Concor. What are the indications for its use? Is it possible to take it while pregnant?

general information

Concor tablets look like small hearts. The main active ingredient is bisoprolol hemifumarate.

Among the auxiliary ones we can highlight:

• magnesium stearate;
• crospovidone;
• cellulose;
• silicon dioxide;
• corn starch;
• calcium hydrogen phosphate.

According to the instructions, Concor affects the cardiac nerve endings, which are most sensitive to the action of adrenaline. During stressful situations, blood vessels narrow greatly, resulting in an increase in blood pressure. The substances that make up the drug slow down the “work” of adrenaline, thereby eliminating tachycardia and lowering blood pressure.

Concor tablets are prescribed in several cases:

1. Chronic form of heart failure.
2. Unstable heart rhythm.
3. Mitral valve prolapse.
4. Tachycardia.
5. Hypertension.
6. Some types of extrasystole. This is a condition in which the heart or its parts are unstable.
7. Ischemia.

There are cases when taking Concor tablets is strictly contraindicated:

1. Intolerance to one of the components included in the composition.
2. Blood pressure too low.
3. Blood circulation disorders.
4. Acidosis.
5. Asthma.
6. Cardiogenic shock. This is a condition in which the myocardium loses its ability to contract. The result is a disruption of the blood supply to almost all organs and tissues of the body.
7. Sick sinus syndrome. This is a pathology characterized by heart rhythm disturbances.
8. Raynaud's disease. A disease whose main symptom is spasm of blood vessels and, as a result, disruption of the blood circulation process.

Side effects may occur while taking the drug. They affect many organs and systems of the body.

1. Feeling of numbness and coldness in the arms and legs.
2. Angina and bradycardia.
3. Headache and dizziness.
4. Depression, sleep problems.
5. Conjunctivitis, visual impairment.
6. Allergic runny nose.
7. Bronchospasm.
8. Nausea and vomiting, bowel dysfunction.
9. Muscle weakness, cramps.
10. Men have problems with potency.
11. Itching, excessive sweating, redness of the skin.
12. Agranulocytosis, thrombocytopenia, increased levels of ALT and AST.

Pregnancy is a time when you need to take your health as seriously as possible. Those medications that could be taken before conception can lead to irreparable problems in the development of the child. What can you say about Concor?

As mentioned above, this medicine is mainly prescribed in the treatment of diseases of the cardiovascular system. You need to drink it according to the regimen drawn up by your doctor. A single dose is calculated depending on the severity of the disease and the severity of symptoms.

Sometimes during pregnancy, the use of Concor may seem quite acceptable. This applies to cases when a woman’s blood pressure rises. However, it is better not to take risks. It is not known exactly how Concor works during pregnancy. Only one thing has been proven - it negatively affects blood flow in the placenta. And this, in turn, leads to pathologies in the development of the fetus.

If the doctor decides that the use of Concor cannot be avoided, you should pay attention to several points:

1. If treatment is carried out in the third trimester, it should be stopped approximately three days before the expected date of birth.
2. The newborn should be examined as soon as possible. Some children whose mothers took Concor tablets during pregnancy may develop bradycardia and hypoglycemia.
3. It is also not recommended to take the product during breastfeeding. Otherwise, lactation should be stopped.

It is up to the attending physician to decide whether it is worth or not to be treated with the drug.

Each person has an individual heartbeat rhythm. Stressful situations, grief, melancholy increase the number of contractions of the heart muscle. People describe their feelings with one phrase - “the heart is ready to jump out of the chest.” This condition is a physiological norm.

• General information
• Features of treatment for pregnant women
• Low blood pressure due to increased heart rate
• Hypertension and tachycardia
• Microelements and vitamins
• Solving the problem with abnormal rhythm
• Beta blockers
• Calcium channel inhibitors
• Potassium blockers
• Membrane stabilizing drugs
• Conclusion

But if there are no apparent reasons for the rapid heartbeat, and the number of heart beats in an adult reaches 90 beats per minute or more, doctors may suspect tachycardia.

We suggest you read: How to relieve an attack of bradycardia - Treatment of hypertension

To confirm the diagnosis, an examination will be required. Based on its results, tablets for tachycardia are prescribed as part of complex treatment.

General information

An attack of tachycardia causes chaotic contractions of the heart, which causes disruption of blood flow to the ventricles of the organ. If you ignore palpitations that occur for no apparent reason, the risk of developing heart failure increases.

When prescribing medications for tachycardia, the doctor must take into account the reasons that caused the increase in heart rate.

For the sinus type of disease, caused by stress or excessive physical activity, it is advisable to use sedative medications, for example, Seduxen, Relanium. If ventricular tachycardia is diagnosed, the patient is prescribed antiarrhythmic drugs.

Oral medication is excluded if a person has paroxysmal tachycardia. To stabilize the patient’s condition as quickly as possible, it is better to administer medications prescribed by the doctor intravenously. With the bloodstream they will go directly to the heart.

During the period of bearing a child, the female body experiences increased stress. That is why tachycardia is often diagnosed in pregnant women.

The most common cause is nervousness. In this case, the expectant mother should calm down and visit more often where there is a source of good mood. It is important to remember that attacks of rapid heartbeat are very dangerous for the development of the unborn child.

The list of drugs approved for pregnant women is extremely limited. To improve the functioning of the heart, the doctor may prescribe the following medications:

• “Panangin”, “Magne B6” - contain magnesium, which has a positive effect on the condition of the heart muscle;
• “Valerian”, “Motherwort” - have a sedative effect;
• “Propranolol”, “Verapamil” - help regulate the impulse of the heart muscle, reducing it to natural levels.

The given list is conditional. The exact prescription must be made exclusively by a doctor.

Patients whose history, in addition to tachycardia, includes low blood pressure, should always have medications prescribed by a doctor in their home medicine cabinet in order to quickly take them during an attack and avoid cerebral edema.

Often, medicine for tachycardia lowers blood pressure. This significantly narrows the range of medications recommended for use.

In case of diagnosed arterial hypotension, the following are prescribed to regulate the heartbeat:

• "Grandaxin", which has a calming effect;
• "Mezapam", which reduces the excitement of the nervous system;
• "Phenazepam", which has anticonvulsant properties.

In patients with tachycardia and high blood pressure, prescribed medications should reduce cerebral vascular spasm. This will avoid minor and major hemorrhages.

Unsystematic use of medications entails not only disruption of the heart, but also the development of depression and apathy.

Cases of simultaneous manifestation of symptoms of tachycardia and hypertension are extremely rare. However, leaving them without medical attention is very life-threatening.

Among the medications indicated for taking are:

• "Diroton";
• "Corinfar";
• "Enap";
• "Verapamil."

These medications can simultaneously improve the heartbeat and gradually reduce blood pressure.

It is impossible to improve the functioning of the heart without maintaining sufficient levels of vitamins and microelements in the body. Their lack negatively affects the state of the nervous system, which makes a person more often nervous and worried. Add to this physical inactivity and poor nutrition and you get a heartbeat disorder.

The work of the heart is positively affected by:

• selenium - provides protection to vascular walls and heart tissue;
• potassium - normalizes nerve impulses;
• phosphorus - responsible for the transmission of impulses.

Not only microelements, but also vitamins are needed to restore heart rhythm and prevent tachycardia.

However, even with adequate nutrition, it is impossible to cover the daily need for vitamins and minerals solely with food, so it is recommended to take special medications.

Tachycardia and arrhythmia are interrelated conditions. They should be treated exclusively under the supervision of a specialist. Only detailed examinations will allow you to correctly prescribe pills for tachycardia and heart rhythm disturbances.

The problem of restoring rhythm is solved with the help of drugs that are formed into such groups.

Concor is a beta-blocking drug that is widely used in medical practice. The range of diseases for which this drug is prescribed is very wide - almost all major cardiac diseases, including tachycardia. Concor is the trade name of bisoprolol, a selective adrenergic blocker that is characterized by high efficiency and potency.

The drug has an antiarrhythmic, hypotensive and antianginal effect, significantly reduces the contractility of the heart muscle by reducing heart rate and inhibiting cAMP. During the first days after administration, an increase in cardiac output is observed, which returns to normal after 2-3 days. Within therapeutic dosages, the drug helps well against tachycardia, but does not have a cardiodepressive effect, does not retain sodium ions and does not affect metabolism involving glucose.

Instructions for use of Concor (Method and dosage)

The instructions for Concor tablets prescribe taking the drug orally, once a day, in the morning. The instructions for using the medicine also indicate that it should be taken with a small amount of water without chewing.

How to take Concor for arterial hypertension and angina pectoris

The dose of the blood pressure medication Concor is selected individually, taking into account the clinical picture of the disease and the patient’s condition. The initial dose is 5 mg once a day. If necessary, it is increased by 5 mg once a day. For the treatment of arterial hypertension and angina pectoris, the highest recommended dose is 20 mg per day.

For chronic heart failure, the usual treatment regimen includes the use of ACE inhibitors or angiotensin blockers, diuretics, beta-blockers and cardiac glycosides.

A prerequisite for drug therapy is a stable chronic course of heart failure without exacerbations. The maximum recommended dose for the treatment of this pathology is 10 mg once a day.

At the moment, there is not enough data on the use of the drug in children, which is why Concor tablets are not recommended for children under 18 years of age.

How long can you take the drug

The summary does not limit the duration of taking the drug. Authoritative Internet resources, for example, Wikipedia, also do not provide clear instructions on this issue, saying only that the course of treatment is long-term and is determined by the attending physician.

There is also insufficient data regarding the use of the drug in people with chronic heart failure complicated by diabetes mellitus , severe damage to the liver and kidneys, or congenital heart defects with severe hemodynamic disorders, for which the drug Concor should be prescribed with caution in this category of patients.

Reviews and analogues

Reviews about the drug Concor are mixed. Some patients claim that the drug helped them normalize blood pressure and improve their overall well-being. Patients attribute its relatively low cost to the advantages of the drug.

There are also a lot of negative comments. People complain that in the first days of treatment they had a severe headache, general weakness, and muscle cramps. Some hypertensive patients complain that even a week after the start of therapy, blood pressure did not normalize.

Overdose

Symptoms of overdose: bradycardia , severe decrease in blood pressure, AV block, bronchospasm, hypoglycemia and acute heart failure.

Treatment: stop taking the medication, start symptomatic therapy.

For bradycardia intravenous atropine . With a strong decrease in pressure - intravenous administration of vasopressor drugs and plasma-substituting solutions .

In case of exacerbation of chronic heart failure - administration of diuretics and vasodilators .

For AV blockade beta-adrenergic agonists are prescribed , and, if necessary, an artificial pacemaker is installed.

For hypoglycemia , administer a glucose solution.

For bronchospasm, it is recommended to prescribe aminophylline and β2-adrenergic agonists .

Drug overdose

Concor for high blood pressure should be consumed in the dosage indicated in the instructions or recommended by a medical specialist. If the maximum permissible dose of the drug is exceeded, the following painful symptoms are likely to occur:

• Hypoglycemia;
• A sharp decrease in blood pressure to critical levels (hypotonic crisis);
• Bronchial spasms;
• Bradycardia (slow heart rate);
• Atrioventricular block;
• Heart failure occurring in acute form.

With this clinical picture, the first thing you need to do is flush the patient’s stomach and call an ambulance.

An overdose of the drug can cause an attack of suffocation

Treatment for an overdose of Concor tablets is symptomatic. With a significant decrease in blood pressure, a plasma replacement solution is injected into the body, and vasopressor medications are prescribed.

In case of hypoglycemia, measures are taken to increase blood sugar levels. In case of bronchial spasms and respiratory dysfunction, the drug Aminophylline is used.

If the pulse is slow, intravenous injections of Atropine are given. If, against the background of an overdose of Concor, heart failure develops, drug therapy involves the use of diuretics and vasodilators.

Interaction

Not recommended combinations

Antiarrhythmic drugs of the first class, when used together with Bisoprolol, can reduce the conductivity and contractility of the heart.

Antihypertensives taken with Bisoprolol may cause bradycardia , decreased cardiac output and vasodilation .

Combinations requiring caution

Class 3 antiarrhythmic drugs (amiodarone) and parasympathomimetics increase AV conduction disturbances.

Topical β-blockers

The effect of hypoglycemic agents is enhanced when used with Bisoprolol.

Cardiac glycosides, when used together with Bisoprolol, lead to the development of bradycardia.

Nonsteroidal anti-inflammatory drugs reduce the hypotensive effect of Bisoprolol.

The use of Bisoprolol with non-selective adrenergic agonists enhances the vasoconstrictor effects of these drugs, leading to increased blood pressure.

Mefloquine when used with Bisoprolol may increase the possibility of developing bradycardia.

MAO inhibitors enhance the hypotensive effect of beta-blockers.

The effectiveness of the drug for tachycardia and its composition

Below, in full detail, what is included in Concor and how its individual components affect tachycardia and a weak heart:

• Bisoprolol fumarate . Main active ingredient. Relieves heart palpitations and lowers blood pressure.
• Calcium hydrophosphate . It is an excipient that serves as a stabilizer.
• Corn starch . An auxiliary substance that helps reliably compress the medicinal powder into a tablet.
• Silica . Prevents caking and clumping of bulk substances included in the tablet.
• Cellulose . A regular filler so that the tablet has mass and shape.
• Magnesium stearate . Excipient. A filler that allows you to create a homogeneous substance.
• Crospovidone . Excipient. Used to improve the dissolution of poorly soluble substances that are part of the drug.
• Hypromellose . Included in the tablet shell.
• Macrogol . It is a binder for all components of the pill shell.
• Dimethicone . Included in the film shell of the tablet.
• Titanium dioxide and iron oxide . Dyes that give the tablet a yellowish or orange tint.

special instructions

It is not recommended to abruptly discontinue the drug or change the recommended dosage without consulting a specialist, as this may cause a temporary deterioration in heart function.

Use with caution in the following cases:

• diabetes mellitus with symptoms of hypoglycemia ;
• carrying out desensitizing treatment;
• Prinzmetal's angina;
• strict diet;
• mild or moderate disturbance of peripheral circulation from the arteries;
• AV block of the first degree;
• psoriasis.

Dosages and overdose

Please note that dosages in all cases are determined individually. We cannot give recommendations to our readers because we do not have information about the medical history or complete health record of the person. Official sources indicate that the intake is carried out in an increasing manner - the initial dosages can be within 1.

We suggest you read: Exercises for the heart during tachycardia

In case of an overdose of Concor, a person may experience symptoms such as bradycardia, bronchospasm, severe hypotension or heart failure. If the first symptoms of an overdose appear, it is recommended to stop treatment with this drug.

Concor's analogues

Level 4 ATC code matches:
Biol

Metocard

Metozok

Nebilet

Nebilong

Betaxolol

Bisogamma

Aritel

Cordinorm

Vasocardin

Corvitol

Bidop

Bisoprolol

Nebivolol

Biprol

Bisoprol

Concor Cor

Lokren

Niperten

Betaloc ZOK

Due to the relatively high price of the drug, patients often have a question: what to replace Concor with. Bicard, Bisokard, Bisoprolol Sandoz, Bisoprolol-Apotex, Bisoprolol-Maxpharma, Bisoprolol-Richter, Bisoprofar, Bisostad, Cordinorm, Concor Cor, Coronal - this is just a small list of what can replace Concor.

There is also a Russian analogue of Concor - the drug Biprol . The medicine and its analogs are in different price categories; the price of analogues is usually lower. For example, the above-mentioned substitute for Concor Biprol 5 mg No. 28 will cost 133-145 rubles, which is almost three times cheaper than a drug from Merck of the same dosage.

Concor in the fight against tachycardia: effectiveness, dosage and contraindications

The medicine "Concor" is prescribed only by a doctor after an examination. The drug is recommended to be taken in the following cases:

• high blood pressure;
• coronary heart disease, as well as prevention of attacks;
• heart failure that has become chronic.

Like any other medicine, Concor has a number of contraindications:

• individual intolerance to any components of the drug;
• heart failure in the acute stage;
• violation of the acid-base balance in the patient’s body;
• hormonally active tumors;
• severe bronchial asthma;
• hypotension, bradycardia;
• various forms of heart block;
• myocardial infarction and its complications;
• disturbances in the blood supply to organs;
• Raynaud's disease.

When used over a long period of time or if the prescription is not followed, the drug can cause some side effects:

• decreased heart rate;
• exacerbation of heart failure;

• migraine and dizziness;
• bronchospasm;
• indigestion;
• severe drop in blood pressure;
• drowsiness, general weakness of the body.

Tachycardia is a disorder in which the heart beats more than 100 beats per minute. You can get rid of this disease in various ways, but it is best to start taking the drug “Concor”. Its effectiveness has been confirmed by numerous studies and laboratory tests.

Below, in full detail, what is included in Concor and how its individual components affect tachycardia and a weak heart:

• Bisoprolol fumarate. Main active ingredient. Relieves heart palpitations and lowers blood pressure.
• Calcium hydrophosphate. It is an excipient that serves as a stabilizer.
• Corn starch. An auxiliary substance that helps reliably compress the medicinal powder into a tablet.
• Silica. Prevents caking and clumping of bulk substances included in the tablet.
• Cellulose. A regular filler so that the tablet has mass and shape.
• Magnesium stearate. Excipient. A filler that allows you to create a homogeneous substance.
• Crospovidone. Excipient. Used to improve the dissolution of poorly soluble substances that are part of the drug.
• Hypromellose. Included in the tablet shell.
• Macrogol. It is a binder for all components of the pill shell.
• Dimethicone. Included in the film shell of the tablet.
• Titanium dioxide and iron oxide. Dyes that give the tablet a yellowish or orange tint.

Concor should be taken for the following heart ailments and types of tachycardia:

• tachycardia;
• high blood pressure;
• chronic heart failure;
• coronary heart disease (CHD), prevention of angina attacks.

This table details how to properly take Concor for tachycardia, kidney and liver problems, and also in old age.

If Concor is taken simultaneously with other drugs, you must remember that undesirable consequences often occur.

• when Concor is used with drugs that lower blood pressure, their effect is greatly enhanced;
• with simultaneous use of the drug with clonidine, methyldopa, moxonidine, rilmenidine in a sick person, the heart rate (HR) is greatly reduced;
• when taken with beta-adrenergic agonists (isoprenaline, dobutamine, etc.), the effect of both drugs is sharply reduced;
• if you use Nifedipine with Concor, the person will experience severe hypotension and impaired cardiac contractility;
• when using Concor with Verapamil, blood pressure decreases significantly and heart rate decreases, and if one of the drugs is abruptly discontinued, a significant jump in blood pressure occurs;
• the use of Concor with injections or insulin tablets leads to a sharp decrease in blood sugar.

Side effects

This medication has various side effects that you need to know about before actively taking it:

• bradycardia;
• worsening of chronic heart failure;
• significant decrease in blood pressure;
• severe headache, dizziness (disappears 1-2 weeks after starting the drug);
• bronchospasm in asthmatics;
• nausea, vomiting;
• bowel dysfunction (constipation, diarrhea);
• skin rashes and other allergic reactions;
• muscle weakness, increased fatigue, numbness in the limbs, chills;
• asthenic syndrome.

Contraindications

Concor has many contraindications, and if a non-healthy person suffers from certain diseases, then he is strictly forbidden to take this drug:

• acute heart failure;
• pheochromocytoma;
• sick sinus syndrome;
• low blood pressure;
• developing or progressive bradycardia;
• cardiogenic shock, acidosis;
• heart block;
• peripheral circulatory disorders (including Raynaud's disease);
• severe bronchial asthma;
• individual intolerance to the drug.

Analogs

Concor has many analogues that are in no way inferior to the original, since they contain the same healing components. This table describes all analogues of Concor and their approximate cost.

Doctors' opinion

Many cardiologists consider Concor to be a very effective remedy that successfully fights tachycardia and hypertension. It eliminates tachycardia within 3-4 months of daily use and prevents its subsequent occurrence. Thanks to this drug, numerous patients felt vigorous and healthy again. Concor has many analogues and is sold in pharmacies at a low price.

Concor has many side effects that negatively affect poor health. This medicine does not combine very well with other medications, and sick people are sometimes forced to take several medications at the same time. Therefore, not all people suffering from tachycardia can use Concor.

Reviews about Concor

Reviews from doctors about Concor blood pressure pills generally fit into the average statistical picture of reports about beta-blockers. The drug has its advantages and disadvantages.

The forums also contain ample assessments of the effectiveness of the drug. The most frequently asked question: do Concor tablets reduce blood pressure? It should be remembered that effectiveness highly depends on the individual characteristics of each individual patient.

Nebilet or Concor - which is better?

Both drugs belong to the group of beta-blockers. Nebilet, from a theoretical point of view, has a stronger vasodilatory effect and is more likely to cause undesirable effects (headaches) due to excessive vasodilating effects. In this case, the drug of choice is Concor.

Egilok or Concor - which is better?

The products are similar in almost all respects. One drug can be easily replaced with another during treatment. 5 mg of Concor is equivalent to 50 mg of Egilok.

Lokren or Concor - which is better?

Compared to Concor, Lokren has a more prolonged effect, greater affinity for specific receptors and, therefore, the most stable plasma concentration. Medicine prices are comparable.

Coronal or Concor - which is better?

These products are interchangeable analogues with the same active ingredient. Coronal is more affordable from a financial point of view, so the choice between drugs should be made based on considerations of economic feasibility and the individual characteristics of the patient.

Bisoprolol or Concor - which is better?

The answer to this question is identical to the previous answer. These drugs are analogues, but Bisoprolol has a lower price.

What is the difference between Concor Cor and Concor?

The most common question about the comparative effectiveness of drugs: what is the difference between Concor and Concor Cor ? Bisoprolol as an active ingredient . The main difference between the drugs is the presence of tablets with a dosage of 2.5 mg in Concor Cor.

How to take Concor

Take Concor only as prescribed by your doctor and in the dosage he or she prescribes. Do not prescribe this medication for yourself or try to adjust the dosage yourself. Perhaps over time the doctor will decide to lower or increase the dosage of the drug. You should regularly visit your doctor every few weeks for follow-up examinations and consultations. Concor should be taken every day, regardless of your health and blood pressure levels.

Do not stop taking this medicine because your blood pressure has returned to normal. Patients who voluntarily stop medications may experience a hypertensive crisis, heart attack, stroke, or decompensated heart failure. This may result in disability or death. If you want to reduce the dosage or stop taking any medications, discuss this with your doctor. Until you get his approval, stick to the same daily pill regimen.

Concor can be taken before or after meals, as is convenient for you. Eating does not affect the rate of absorption or potency of this medication. Try to take your blood pressure pills at the same time every day. Concor needs to be taken for a long time, perhaps even for life. This medicine is not addictive and does not have a negative effect on metabolism. It begins to act no earlier than after 1-2 weeks of daily use, so it is not suitable for situations where emergency assistance is needed.

Can I take Concor in the evening, at night?

Concor can be taken at night, but it is still better to do it in the first half of the day. In most patients, blood pressure does not rise in the morning or afternoon, but in the evening. Bisoprolol tablets do not begin to act immediately, but only a few hours after administration. The medicine taken in the first half will act in full force just in the evening.

If your blood pressure rises in the evening, you have a headache, feel sick, or other symptoms of a hypertensive crisis appear, then it is too late to take Concor. We need other medications that work faster. Study the article “Hypertensive crisis: emergency care” and do what it says.

Sometimes there are patients whose blood pressure rises at dawn and in the mornings, and not in the evenings, like everyone else. Perhaps 24-hour blood pressure monitoring has shown that you are one of those rare people. In this case, it is more beneficial for you to take Concor in the evening or at night.

Can I split the tablet in half?

The Concor tablet can be divided in half, but cannot be crushed or chewed. The tablets should not be divided into 4 parts. If you need to take bisoprolol 1.25 mg per day for heart failure, then buy Concor Cor tablets and divide them in half. For hypertension, it is not recommended to take 1.25 mg of bisoprolol per day, even together with other blood pressure pills. This dose is considered too low. It is unlikely that it will protect you from myocardial infarction and other consequences of hypertension.

Is it possible to drink Concor with low blood pressure?

Stop taking Concor if your “upper” systolic blood pressure drops below 100 mmHg. Art., you feel dizzy and weak due to hypotension. If the “upper” systolic pressure remains above 100 mmHg. Art. and you feel fine - continue taking the medicine. At your next visit to your doctor, ask if you should reduce the dosage of your hypertension pills. But do not stop taking them without permission.

What should your pulse be when taking this medicine?

You should strive for a resting heart rate of 55-60 beats per minute. At this heart rate, you have the lowest risk of dying from a myocardial infarction or decompensated heart failure. A competent doctor will first prescribe Concor at a low dose for daily use, and then gradually increase the dosage until the patient's resting pulse drops to the specified target values. Of course, the dose of bisoprolol can be increased only if the patient tolerates this drug well. You should not achieve an optimal heart rate at the expense of severe side effects from the medication.

How to cancel Concor?

Concor should be discontinued slowly and carefully, otherwise there may be a significant increase in blood pressure by “ricocheting”, pulse surges and heart rhythm disturbances. Stopping it too quickly is deadly and can lead to a heart attack or stroke. First you need to slightly reduce the daily dose, then monitor your well-being and heart rate for several days. If everything is fine, reduce the dose further. And so gradually completely stop taking this medicine. Wait at least 3 days, or even a whole week, before reducing the dosage again. One day is not enough.

Unfortunately, there is no single scheme for discontinuing Concor tablets and other bisoprolol preparations. Foreign sites write that cancellation should take at least one week. You can reduce the dosage by 1.25 mg or by half each time. If you don't want to take risks, then use the regimen 5 mg - 3.75 mg - 2.5 mg - 1.25 mg - 0. A faster and riskier option: 5 mg - 2.5 mg - 0. Discuss stopping the beta blocker with a doctor who sees many patients and has enough experience.

Concor price, where to buy

In Russia, the price of Concor 5 mg No. 50 ranges from 306-340 rubles; buying 50 tablets of 10 mg will cost 463-575 rubles. The cost of the medicine (5 mg No. 50) in Moscow starts from 313 rubles.

The price of Concor tablets in Ukraine 10 mg No. 50 averages 162 hryvnia.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

ZdravCity

• Concor KOR tablets p.p.o.
  2.5 mg 30 pcs. Merck KGaA/LLC Nanolek RUB 152 order
• Concor tablets p.p.o. 10 mg 30 pcs. Merck KGaA

  RUB 286 order

• Concor tablets p.p.o. 5 mg 30 pcs. Merck KGaA

  RUB 199 order

• Concor cor tablets p.p.o. 2.5 mg 30 pcs. E. Merck

  RUB 152 order

• Concor tablets p.p.o. 5 mg 30 pcs. Merck KGaA/Nanolek LLC

  RUB 203 order

Pharmacy Dialogue

• Concor Cor (tab.p.pl/vol. 2.5 mg No. 30)Merck KgaA

  140 rub. order

• Concor (tab. 10 mg No. 50) Merck KgaA

  RUB 495 order

• Concor (table 5 mg No. 30) Merck KgaA

  206 rub. order

• Concor (tab. 10 mg No. 30) Merck KgaA

  RUB 302 order

• Concor AM (tablet 5mg+5mg No. 30) Egis

  RUB 421 order

show more

Pharmacy24

• Concor 5 mg N30 tablets Merck KGaA, Nimechchina
  108 UAH order
• Concor 5 mg N50 tablets Merck KGaA, Nimechchina

  159 UAH order

• Concor 10 mg No. 30 tablets Merck KGaA, Nimechchina

  168 UAH order

• Concor Cor 2.5 mg No. 30 tablets Merck KGaA, Nimechchina

  95 UAH order

• Concor 10 mg N50 tablets Merck KGaA, Nimechchina

  292 UAH. order

PaniPharmacy

• Concor tablets Concor tablets. 10 mg No. 50 Germany, Merck KGaA

  300 UAH order

• Concor tablets Concor tablets. 5mg No. 30 Germany, Merck KGaA

  127 UAH order

• Concor tablets Concor tablets. 10 mg No. 30 Germany, Merck KGaA

  191 UAH order

• Concor cor tablets Concor cor tablets, film-coated 2.5 mg No. 30 Germany, Merck KGaA

  103 UAH order

• Concor tablets Concor tablet 5mg No. 50 Germany, Merck KGaA

  167 UAH order

show more

Price for Concor

Video on the topic

How and how much to drink Concor to improve your condition? Answers in the video:

Thus, many hypertensive patients are interested in the question of how long Concor can be taken so as not to cause addiction and the development of side effects. This drug belongs to the group of beta1-blockers, and there is no addiction to it. You can drink it indefinitely, but under the supervision of a doctor. Some patients complain that after a while the drug begins to reduce blood pressure worse. But most likely this condition is associated with the progression of the disease and an incorrectly selected treatment regimen.

The information on the MyMedNews.ru website is for reference and general information, collected from publicly available sources and cannot serve as a basis for making a decision on the use of medications in the course of treatment.

MyMedNews.ru

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Analogs

Concor has many analogues that are in no way inferior to the original, since they contain the same healing components. This table describes all analogues of Concor and their approximate cost.

What can replace Concor?

Concor effectively lowers blood pressure. But when treatment takes a long time, addiction to the active substances of the drug may occur. Therefore, in the process of adjusting treatment, Concor can be replaced with similar beta blockers.

Let's consider several of the most frequently prescribed analogs that can replace the original.

Domestic Bisoprolol

Russian-made bisoprolol is supplied to pharmacy chains in tablets, dosages of 5 and 10 mg.

A similar drug differs from the original in budget cost. There is little demand for a domestic beta blocker, although reviews are good. The drug has a similar effect on the heart muscle.

Coronal

Coronal and Concor are prescribed for high blood pressure and as a preventive measure.

Coronal is used for ischemic disease and for varying degrees of hypertension. The main difference from the original is the manufacturer and lower cost of the antihypertensive drug.

Egilok

The main active component of the beta blocker Egilok is metoprolol.

Despite the differences in active substances, Egilok has similar indications to the original with contraindications. The drugs have many common side effects.

There are differences between the medicinal formulations in the mechanism of action when prescribed for high blood pressure:

1. duration of the result. Egilok begins to act within 20 minutes from the start of administration. But the active components leave the body faster. Therefore, tablets are taken 2 to 3 times a day;
2. You should not take Egilok before meals. The medicine is absorbed better during meals.

Why and what type of beta blocker is recommended to be prescribed is decided by the doctor after examination. You can also read reviews about analogues.

Anaprilin

Anaprilin belongs to the first medicinal compositions from the category of beta blockers. The drug has many contraindications, including problems with potency, depression, and a cough may develop.

For long-term treatment of hypertension, it is recommended to prescribe modern beta blockers, which have fewer contraindications and good reviews from doctors, as well as a long period of action.

Nebilet

The main component of Nebilet is nebivolol.

Compared to Concor, Nebilet dilates peripheral blood vessels, therefore it is one of the most effective beta blockers.

Nebilet is also very expensive when compared to other adrenaline receptor blockers.

Carvedilol

By spreading the action of the active components to peripheral vessels, Carvedilol is able to simultaneously block alpha and beta receptors.

Serious side effects of the drug include spasms in the bronchi. Concor is better tolerated for high blood pressure, but it cannot be used as the only antihypertensive drug.

Despite the fact that many beta blockers similar to Concor are produced, and drugs that are similar in effect, experts advise purchasing the original when prescribing. This is explained by the fact that the drug, being a modern beta blocker, effectively relieves the symptoms of hypertension, allowing the therapeutic result to be maintained for a long time.

Composition and effects on the body

Concor (Concor, international name - bisoprolol) belongs to the category of beta-blockers - medications that block stimulation of the heart muscle by impulses from the central nervous system. The main active ingredient of the drug is bisoprolol (bisporolol furamate), which protects the heart from the effects of “stress hormones” - adrenaline, norepinephrine, etc., which enter the bloodstream during stressful situations. Bisoprolol has a selective effect - it affects exclusively the myocardium, without affecting other organs, due to which the number of side effects is significantly reduced.

The effect of Concor on the heart and circulatory system is as follows:

• decrease in heart rate and the need of the heart muscle for free oxygen;
• reducing the speed of impulses passing through the myocardium, stabilizing the heartbeat;
• elimination of ischemic and degenerative phenomena in tissues;
• a reduction in the minute volume of blood in one cardiac output, as a result of which the supply of oxygen and glucose to the fibers is normalized;
• elimination of discomfort and pain in the heart area.

In addition to the active ingredient, Concor contains additional components (calcium hydrogen phosphate, corn starch, etc.) that maintain the activity of bisoprolol and ensure long-term storage of the drug.

Concor is available in the form of light yellow tablets with a characteristic shape (they look like convex hearts with a line in the middle) of 5 and 10 mg in blisters, which are packaged in paper packages of 3-10 pieces. The medicine is stored at a temperature not exceeding 25 degrees, the shelf life is 5 years.

Advice: when buying Concor blood pressure tablets, you need to study the doctor’s prescription and the recommended dosage - increasing the proportions of the active substance can cause serious harm to your health.

Analogues of the drug include medications containing the same active substance: “Bisoprolol”, “Bisocard”, “Coronal”, “Bisoprol”, etc.

Interaction with other drugs

If Concor is taken simultaneously with other drugs, you must remember that undesirable consequences often occur.

• when Concor is used with drugs that lower blood pressure, their effect is greatly enhanced;
• with simultaneous use of the drug with clonidine, methyldopa, moxonidine, rilmenidine in a sick person, the heart rate (HR) is greatly reduced;
• when taken with beta-adrenergic agonists (isoprenaline, dobutamine, etc.), the effect of both drugs is sharply reduced;
• if you use Nifedipine with Concor, the person will experience severe hypotension and impaired cardiac contractility;
• when using Concor with Verapamil, blood pressure decreases significantly and heart rate decreases, and if one of the drugs is abruptly discontinued, a significant jump in blood pressure occurs;
• the use of Concor with injections or insulin tablets leads to a sharp decrease in blood sugar.

Concor reduces pressure or not

Concor contains a beta-blocker bisoprolol with a selective effect, it reduces blood pressure and at the same time slows down the pulse. The drug primarily affects the vascular wall and heart function. In low and medium dosages (up to 20 mg per day) it does not worsen metabolic processes (not contraindicated for diabetics or obesity). Concor can be taken for high blood pressure and rapid pulse in bronchial asthma.

The effectiveness of the drug for hypertension is explained by the fact that Concor binds to adrenaline (stress hormone) receptors in the heart muscle and blocks them. This slows down the frequency and strength of heart contractions, and a smaller volume of blood is released into the vascular bed with each beat.

When Concor acts on the arterial wall, it relaxes, the tone decreases, and therefore the blood pressure decreases. Bisoprolol in the tablets also reduces the release of renin by the kidneys, this prevents the launch of a cascade of reactions (renin-angiotensin-aldosterone) leading to vasospasm.

All these pharmacological effects reduce the need for oxygen in the heart muscle and reduce the load on the heart. Therefore, Concor has a beneficial effect on the course of ischemic disease (angina, heart attack) and heart failure (weakness of myocardial contractions).

Course of treatment with Concor, or how long to take the drug

Patients with cardiovascular diseases are often prescribed a drug based on bisoprolol, under the trade name Concor. How long you can take this remedy is an important aspect of therapy that must be taken into account when receiving medication.

general description

Concor is available in the form of film-coated tablets. The active element of the drug is bisoprolol fumarate, and the auxiliary elements are calcium hydrogen phosphate anhydrous crospovidone, MCC, starch, magnesium stearate, colloidal silicon dioxide.

Concor can be prescribed if:

• hypertension;
• chronic heart failure (CHF);
• coronary heart disease (CHD): stable angina.

The medication has hypotensive, antianginal, beta1-adrenergic blocking and antiarrhythmic effects. A single use in people with coronary artery disease (in the absence of symptoms of CHF) helps to reduce heart rate, reduce the stroke volume of the heart, ejection fraction and myocardial oxygen demand.

Long-term therapy provides a reduction in the initially increased total peripheral vascular resistance.

How long can you take Concor without interruption?

The drug is designed for long-term use (from 12 weeks) and is usually used as part of maintenance therapy.

The exact duration of treatment is not indicated in the instructions, so it must be determined by the doctor, based on the patient’s condition and the diagnosis.

For example, to reduce heart rate during ischemia, a single dose is sufficient. To eliminate the manifestations of ischemia, Concor can be taken once a week. For mild arterial hypertension, the medicine is used until a lasting improvement is achieved, and for severe hypertension - for life.

How to use?

The medication is indicated for oral use. The tablets are taken without crushing into powder or chewing, once a day with a small amount of water. Do this in the morning (before, during or after meals).

Overdoses and contraindications

Typically, an overdose is accompanied by a pronounced decrease in pressure, the development of AV block, hypoglycemia, explicit bradycardia, acute heart failure, and bronchospasm. The response to a single dose of the drug varies among patients (there is evidence that people with CHF are more sensitive).

In case of overdose, the medication should be discontinued and supportive symptomatic therapy should be started:

1. with a decrease in blood pressure : intravenous administration of vasopressor medications, plasma-substituting solutions;
2. for bradycardia : administration of atropine. If the effect is not sufficiently pronounced, drugs with a positive chronotropic effect are prescribed. It is also possible to use an artificial pacemaker;
3. for hypoglycemia : intravenous administration of glucose;
4. for AV blockade : treatment with beta-agonists, for example, epinephrine. It is possible to install an artificial pacemaker;
5. for bronchospasm : prescription of bronchodilators, including aminophylline and/or beta2-adrenergic agonists;
6. during exacerbation of CHF : intravenous administration of vasodilators, diuretics, agents with a positive inotropic effect.

The use of Concor is prohibited for:

• individual intolerance to bisoprolol or auxiliary components;
• atrioventricular block of degree II and III, without pacemaker;
• severe bronchial asthma;
• acute heart failure and CHF (decompensation), requiring inotropic treatment;
• sick sinus syndrome;
• severe hypotension;
• sinoatrial block;
• pheochromocytoma (in people not taking alpha-blockers);
• explicit bradycardia;
• metabolic acidosis;
• serious dysfunctions of peripheral arterial circulation;
• cardiogenic shock;
• treatment of adolescents and children.

Relative contraindications to taking Concor:

• carrying out desensitizing treatment;
• diabetes mellitus with severe fluctuations in blood glucose levels;
• hyperthyroidism;
• diabetes mellitus type 1;
• severe forms of COPD;
• Prinzmetal's angina;
• following a strict diet;
• severe renal failure;
• AV block degree I;
• psoriasis;
• congenital heart defects;
• liver function disorders;
• heart valve disease with serious hemodynamic dysfunction;
• restrictive cardiomyopathy;
• CHF with myocardial infarction (if it was observed over the past 3 months).

Sometimes, at the beginning of treatment for hypertension or angina, there is a feeling of increased fatigue, which usually goes away after a few weeks of taking Concor.

Optimal course of treatment with Concor

The average therapeutic course depends on the clinical picture, form and type of pathological process.

Hypertension, stable angina

The treatment regimen is drawn up individually, taking into account the patient’s condition and heart rate. Treatment usually begins with 5 mg once daily. If required, the dose is increased to 10 mg. The maximum daily dose is 20 mg.

Chronic heart failure

Treatment is started in the presence of stable CHF without symptoms of exacerbation. At the beginning of therapy, a special titration phase is carried out under the supervision of a physician.

Treatment begins with taking 1.25 mg of Concor 1 time per day. If the dose is accepted by the body well, it is gradually increased to the maximum (up to 2.5, 3.75, 5, 7.5 and 10 mg).

If the dose is poorly tolerated, it is reduced. The minimum amount of time that must pass since the previous dose increase is 14 days. During titration, it is necessary to monitor blood pressure, heart rate, and the severity of signs of CHF. Symptoms of the disease may worsen after the first tablet.

Hypotension or bradycardia may also occur during or after the titration phase. In all of these cases, dose adjustment of drugs taken in parallel is required. It is also possible to cancel or temporarily reduce the dose of Concor. When the patient's condition returns to normal, treatment is continued or the dose is re-titrated.

Can it be combined with other medications?

"Concor" with incorrect compatibility often provokes undesirable consequences. A disrupted drug combination can enhance or reduce the effect of the active components. Therefore, you should not do anything at your own discretion and self-medicate. Combinations of Concor with medications such as:

• Medicines that relieve symptoms of arrhythmia. It is especially not recommended to combine it with the first class of drugs, in particular with Bisoprolol, since a decrease in cardiac contractility is likely.
• Drugs with antihypertensive effects. Otherwise, when used together with Concor, a strong decrease in pressure and vasodilation occurs.

Indications for use

Concor has a quick effect, the pressure drops in a short period of time.

Cardiologists often prescribe this medicine for problems with the heart and blood vessels, such as:

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• heart failure;
• ischemic disease;
• angina pectoris;
• hypertension.

For high blood pressure, one Concor tablet is enough. Its effect lasts for up to 24 hours. The drug is used for high pulse and high blood pressure.

Concor during pregnancy

If a woman’s blood pressure rises during pregnancy (which happens very often), then one of the drugs that treats arterial hypertension is Concor. The medicine is used only if the health benefits to the expectant mother outweigh the danger to the fetus. The effect of Concor during pregnancy has been little studied, but it is known for sure that the drug can reduce blood flow in the placenta, and this negatively affects the intrauterine development of the baby. When prescribing a drug, laboratory parameters should be monitored and the condition of the fetus should be monitored.