What is Panangin
Panangin is a drug produced in the form of tablets and solution for parenteral administration, intended for the treatment of cardiac pathologies. The composition contains potassium and magnesium aspartate. The active substances are non-toxic and do not have a direct effect on the development of the fetus. The medication has good compatibility, for this reason it is often used as part of complex treatment.
During pregnancy, Panangin should be taken only after a doctor’s prescription.
For treatment, it is best to use the tablet form of the drug, which is gradually absorbed, minimizing the risk of overdose. Panangin does not cause addiction, does not cause drowsiness, and can be used when driving a car.
The instructions for use indicate that Panangin should be taken with caution during pregnancy, especially in the 1st trimester, as well as during lactation. Such limitations are due to the lack of clinical studies among expectant mothers.
Admission rules
According to the instructions, adults take Panangin one or two tablets three times a day. To eliminate the risk of potassium overdose, doctors use a reduced dosage of Panangin for pregnant women - one tablet once or twice a day. The minimum course of taking the drug is 14 days. Subsequent continuation of treatment is agreed with the doctor, with the establishment of a maintenance dose.
The acidic environment of gastric juice can reduce the bioavailability of the drug. This indicates the need to take the pills after meals. Potassium and magnesium can interfere with the absorption of iron salts in the intestines. The drug is used with caution in women with anemia. During pregnancy, you can take Panangin and iron supplements, keeping an interval between doses of at least three hours. Women's reviews of "Panangin" during pregnancy indicate the high effectiveness of the drug against seizures and tachycardia. Efficiency is observed in 85% of cases of use. At the same time, the number of references to the development of undesirable effects is minimal.
Use of Panangin during pregnancy
Taking the drug while pregnant has its own characteristics:
- Self-administration of the drug is prohibited; it can only be taken as prescribed by a specialist, as this can lead to unexpected consequences.
- While taking the drug, the amount of potassium and magnesium in the blood should be monitored. This is necessary to prevent overdose and side effects.
- The recommended form of medication is tablets. Experts do not recommend using the medication intravenously, since its rapid administration increases the risk of developing hyperkalemia and hypermagnesemia.
- If any side effects occur or your health worsens, you should immediately stop taking the drug. This rule applies to all medications prescribed while pregnant.
- Despite the good compatibility of Panangin with other medications, in some cases its combined use with diuretics and ACE inhibitors can cause hyperkalemia.
Taking Panangin at any stage of pregnancy is advisable only in particularly severe cases. If the expectant mother has a slight tachycardia and a moderate lack of minerals, then in this case it is recommended to change the diet and daily routine of the pregnant woman. In cases where this does not produce results, Panangin is prescribed in tablet form.
1st trimester
Experts do not recommend taking Panangin in the early stages of pregnancy, since there is no accurate data on its effect on the fetus. For this reason, the drug is recommended for use only from the 14th week of pregnancy. But at the same time, if the expectant mother has hypokalemia or hypomagnesemia, then Panangin can be taken in the recommended dose.
2nd trimester and 3rd trimester
You can take the drug during these periods as prescribed by a specialist and following the recommended dosage. While taking the medicine, the pregnant woman's blood levels of magnesium and potassium are regularly checked to prevent overdose.
Existing contraindications and side effects
According to the instructions, it is not prohibited to use Panangin during pregnancy. Taking the drug is not allowed in the following cases:
- sensitivity to the components of the synthetic product;
- hyperkalemia, when there is excess potassium in the blood;
- hypermagnesemia with elevated magnesium levels;
- with the development of cardiogenic shock, which is characterized by a critical decrease in blood pressure as a result of low cardiac output;
- myasthenia gravis in severe form;
- disturbance of atrioventricular conduction, since the drug slows down the conduction of nerve impulses from the atria to the ventricles;
- change in acid-base balance towards a decrease in pH;
- acute stage of metabolic acidosis;
- destruction of red blood cells in the blood - hemolysis;
- violation of water-alkaline balance - dehydration;
- decreased function of the adrenal cortex.
“Panangin” is excreted by the kidneys, therefore, in case of organ disease, during a period of chronic or acute failure, a decrease in its filtering abilities is noted. In such cases, treatment with Panangin is carried out under the supervision of a doctor to prevent the accumulation of magnesium and potassium in the body. The drug is also prescribed with caution:
- with severe liver pathologies,
- if there is a threat of edema development,
- with low levels of phosphates in the blood.
As a rule, "Panangin" during pregnancy is prescribed in the first trimester, since comprehensive studies have not been conducted on the effect of the drug on the embryo.
In some cases, the doctor decides to take the drug at the beginning of pregnancy if its use is necessary for medical reasons. The cause may be severe toxicosis, accompanied by loss of fluid and potassium. But the rationality of use is assessed by a specialist after analysis in case of a lack of an element.
Adverse reactions
In some cases, Panangin may cause undesirable reactions of the body to taking the drug. Usually the condition is associated with an overdose of ions of one or both components of the drug. This is manifested by the following symptoms:
- The nervous system reacts with paresthesia (sensitivity disorder accompanied by a feeling of slight tingling, goosebumps or numbness), decreased reflex activity, and sometimes muscle cramps.
- The reaction of the heart and blood vessels is determined by redness of the face and a decrease in blood pressure. It is possible to develop a paradoxical reaction, which is expressed in heart rhythm disturbances (extrasystole), AV block.
- There is difficulty in the respiratory system, and there is a disturbing feeling of heat.
- The gastrointestinal tract is characterized by the appearance of thirst, nausea and vomiting, diarrhea, and burning in the pancreas. As a rule, symptoms are characteristic of people with gastritis and cholecystitis.
At the first signs of side effects and consequences of an overdose, a pregnant woman should immediately stop taking the medication and consult a doctor.
Instructions for use
Below is a diagram of how to drink Panangin during pregnancy:
- The tablets are taken after meals. This is due to the fact that hydrochloric acid present in gastric juice reduces the healing properties of the medication.
- During the therapeutic course, you should stop taking medications that contain magnesium and potassium. For example, you cannot combine taking Panangin with Asparkam, since this will not bring any benefit, but at the same time it will significantly increase the amount of electrolytes.
Parenteral solution:
- Apply 10-20 ml of the drug, which is diluted with 100 ml of glucose.
- If necessary, intravenous administration of the medication can be repeated after 7-8 hours.
1 tablet of Panangin per day - dosage for pregnant women
Dosage
Only a specialist can tell you the exact dosage and duration of taking Panangin during pregnancy. As a rule, adults are prescribed 1 to 3 tablets three times a day. Typically, expectant mothers reduce the dosage to 1 tablet per day. At the same time, the duration of administration is influenced by the reason why the drug is prescribed and the dynamics of the therapy performed.
The need to prescribe the drug
Instructions for use for Panangin often indicate that the drug is undesirable during pregnancy. This is explained by the fact that clinical studies on the effect on the developing fetus have not been conducted. Therefore, Panangin should be used carefully during pregnancy, under the supervision of a doctor.
The medication is available in tablets and solution for infusion, but pregnant women are prescribed to take only pills. The main indication for prescribing Panangin is a lack of potassium and/or magnesium. When the amount of these microelements decreases, the following occurs:
- disturbance of intracellular electrolyte balance;
- changes in sodium-calcium metabolism in tissues;
- nervous disorders appear (depression, tearfulness, sleep disturbance);
- muscle tone is lost (striated and smooth muscles lose the ability to relax and contract normally);
- bones and teeth are destroyed (elements are necessary to ensure the strength of bone structures);
- there are signs of metabolic disorders in tissues (fat or glucose);
- the synthesis of enzymes and hormones decreases.
These disorders not only affect the body of the expectant mother, but also negatively affect the condition of the fetus, causing disturbances in intrauterine development. Panangin allows you to eliminate the problem: microelements penetrate the hemoplacental barrier and allow you not only to restore the health of the mother, but also to provide the unborn child with the necessary elements.
Contraindications
Panangin has an extensive list of restrictions for use:
- dehydration - taking the drug increases the likelihood of developing hyperkalemia, hypermagnesemia;
- failure of protein metabolism at the amino acid level;
- individual intolerance;
- hyperkalemia, hypermagnesemia;
- violation of intracardiac conduction;
- renal failure;
- Addison's disease;
- cardiogenic shock;
- hypocorticism;
- severe form of myasthenia;
- a condition that is accompanied by the breakdown of red blood cells, hemolysis;
- a sharp shift in blood pH to an acidic environment.
Contraindication for use
Drinking Panangin during pregnancy is prohibited if the expectant mother has:
- intolerance to the components of the drug;
- blockade in the myocardium;
- hypermagnesemia;
- hyperkalemia;
- impaired protein metabolism;
- functional kidney failure;
- Addison's disease;
- severe hypotension (below 90 mmHg).
If contraindications are identified, other medications are selected to correct the woman’s problems.
You can take Panangin during pregnancy, but use the medicine with great caution . It should be remembered that taking any medications is undesirable for a child developing in the womb, therefore Panangin is prescribed only to correct problems that have arisen associated with a lack of minerals or to support the myocardium in chronic heart disease.
Side effects
Sometimes taking Panangin can cause certain side effects:
- Nausea, vomiting, diarrhea - these symptoms are most often observed in people who suffer from gastrointestinal diseases.
- Tingling, goosebumps on the arms and legs.
- Hypermagnesemia, which is accompanied by constant thirst, cramps, breathing problems (shortness of breath, lack of air). Excessive amounts of magnesium in the blood can lead to cardiac arrest, but this is more true for the parenteral form, since tablets rarely cause an overdose.
- Bradycardia.
- Impaired impulse conduction in the heart muscle.
Before taking the drug, be sure to consult your doctor!
Is the medicine dangerous during pregnancy?
The effect of Panangin on pregnancy has not been established due to the lack of clinical trial data on this population. This is not surprising, because what pregnant woman would agree to risk the health of her unborn baby? Therefore, the absence of embryotoxic and teratogenic effects of the drug has not been proven.
No one knows whether Panangin is harmful for pregnant women in the early stages. Therefore, doctors prescribe the drug at the beginning of pregnancy only if absolutely necessary. For example, with pronounced symptoms of hypokalemia that threaten the life of the expectant mother.
In late pregnancy, due to the growth and development of the fetus, the need for additional macronutrients increases. Since the formation of organs in the fetus has already occurred, the consequences for the child and the expectant mother of a moderate intake of potassium and magnesium are minimal.
Security
Pregnancy is not a contraindication for treatment with Panangin. However, the attending physician is obliged to make sure that the expectant mother has no other contraindications for using the drug:
- hyperkalemia;
- acute or chronic renal failure;
- disturbances in the conduction of nerve impulses in the heart muscle;
- Addison's disease;
- cardiogenic shock (pressure below 90 mm Hg).
According to doctors, when using Panangin in pregnant women, side effects occur extremely rarely. Prescribing reduced doses of the drug to this category of patients plays a role. The occurrence of nausea, dizziness or frequent bowel movements after taking Panangin is a reason to contact your doctor to adjust the dose or discontinue the drug.
The most dangerous consequence of taking it is the development of hyperkalemia - an increase in the concentration of potassium in the blood above 5 mmol/l. A complication develops in case of an overdose of the drug or with a biased assessment of the human body’s need for potassium ions.
Hyperkalemia is manifested by lethargy, drowsiness, confusion, muscle pain, paralysis of smooth and striated muscles. Among the consequences are a sharp decrease in blood pressure and a decrease in the strength of heart contractions, up to cardiac arrest. The condition requires treatment in a hospital setting with emergency infusion of sodium and calcium solutions.
Analogs
Panangin is an effective medicine that helps compensate for the lack of potassium and magnesium in the body, as well as solve a number of other serious problems. There is only one drug analogous to this medication - Asparkam. They have the same compositions, only Panangin contains minerals in a shell, while Asparkam contains them in a regular white tablet without a film coating.
If a woman does not have problems with the digestive tract, then it makes no difference which of these drugs to take. But in case of an ulcer or enterocolitis, it is better to give preference to Panangin.
The cost of Panangin is about 160 rubles, Asparkam is about 70 rubles.
Reviews
Below are reviews from women in labor and pregnant women about Panangin.
Albina, 28 years old
I took Panangin in the 2nd trimester, since I had arrhythmia, and at the same time adjusted my diet, work and rest schedule. I don’t know which of these helped more, but the arrhythmia went away.
Elizaveta, 21 years old
I took Panangin in the 1st trimester. I had a miscarriage, I don’t know for sure whether the drug was to blame or stress. Now I am wary of any medicine.
Violetta, 32 years old
The doctor prescribed me to take Panangin in the 3rd trimester, since I was diagnosed with a lack of magnesium and potassium. I took the pills for a week, after which I took tests, everything was normal.
Remember, you can take Panangin only after a doctor's prescription. Do not self-medicate to avoid harming yourself or your child.