Does Phenibut raise or lower blood pressure? In what cases is the drug prescribed?

Jumps in blood pressure are often caused not only by the patient’s health condition, but also by external factors.

Among them, environmental conditions, pathologies and constant stress are of greatest importance.

In order to restore blood pressure, psychotropic drugs are most often prescribed. The most important drug is Phenibut.

Letters from our readers

Topic: Grandma's blood pressure has returned to normal!

From: Christina ( [email protected] )

To: Administration otgipertonii.ru

Christina, Moscow

My grandmother’s hypertension is hereditary - most likely, I will have the same problems as I get older.

I accidentally found an article on the Internet that literally saved my grandmother. She was tormented by headaches and had a repeated crisis. I bought the course and monitored the correct treatment.

After 6 weeks she even started talking differently. She said that her head no longer hurts, but she still takes pills for blood pressure. I am sending a link to the article

Composition of the medicinal product and release form

According to the classification of nootropic drugs, Phenibut belongs to the class of aminophenylbutyric acid derivatives. The active ingredient is gamma-amino-beta-phenylbutyric acid hydrochloride.

Pharmacological activity is manifested in the impact on metabolic processes in nerve tissues and the influence on the passage of nerve impulses. It has a positive effect on the rheological characteristics of blood, slows down the formation of blood clots, and improves microcirculation in the brain. The action is associated with an increase in the resistance that the brain exhibits to damage of various natures: from hypoxia to intoxication.

The ability of the drug to stimulate metabolism in the nerve cell and cerebral circulation allows you to obtain the following effects:

• reduce feelings of fear, confusion, panic;
• reduce dizziness, improve reaction, attention;
• improve sleep, prolong wakefulness, increase productivity;
• eliminate nervous tics, muscle spasms, speech impairment;
• get rid of neuroses and depression.

Available in powder form in 100 mg sachets, as well as 250 mg tablets, packaged in blister packs of 10 or 20 pieces.

The powder is white, sour in taste, odorless, crystalline.

Tablets are white, scored, round.

The composition is supplemented by the usual set of binders, including lactose, which can cause allergic reactions if you are intolerant to it.

Since 2014, it has been dispensed in pharmacies with a prescription from a specialized doctor - neurologist, psychiatrist, psychotherapist.

Advice! As evidenced by patient reviews, it is preferable to purchase Phenibut (phenibutum) from Olainfarm (Latvia).

Phenibut and pressure - principle of action

The action has a direct impact on the functioning of parts of the brain. The effect is expressed in restoring the normal functioning of brain cells, improving metabolism and immunity to adverse effects on the body. As a result of regular use, the speed and volume of blood flow in a person increases, microcirculation in the vessels returns to normal, and the transmission of nerve impulses to the central nervous system improves.

What effects does phenibut have on the body:

• antiamnestic;
• antihypoxic;
• psychostimulant;
• antioxidant;
• tranquilizing;
• antiaggregate.

The drug helps normalize the functioning of the nervous system and brain. How does this manifest itself:

• the mental state ceases to be in fear;
• the person becomes more relaxed;
• sleep is normalized;
• the chance of asthenic syndrome occurring is reduced;
• headaches stop bothering you;
• irritability and increased emotionality are reduced;
• increased attentiveness, concentration, reaction, improved memory;
• restoration of interest in favorite activities and increased performance.

After using the drug, a person does not feel tired and drowsy. Apathy and irritability do not appear. Phenibut helps restore the normal state of the body.

Phenibut helps reduce blood pressure in cases where it appears due to nervous disorders and loss of emotional control. The medicine is not an antihypertensive drug. In cardiology, the drug is rarely used for an auxiliary effect.

Indications

The first nootropic drugs appeared in the 60s of the last century. The term “nootropic” was proposed in 1972 by Belgian scientists for a class of drugs that have a positive effect on the higher functions of the nervous system - memory, speech, learning. Unlike psychostimulants, they do not cause restlessness, anxiety, headaches, insomnia, or drug dependence.

Interesting historical fact! Phenibut was included as a mandatory medication in the first aid kit on board the Soyuz spacecraft in 1975. The domestic drug, developed by Professor V.V. Perekalin, helped astronauts overcome stress without reducing their performance.

Initially, nootropics were intended for older patients for the treatment of brain dysfunction associated with Alzheimer's disease, senile dementia, asthenic syndrome, vascular diseases, glaucoma, traumatic brain injury and intoxication.

In subsequent years, their use expanded to many areas of medicine. Neurology, narcology, and psychiatry in modern practice cannot do without these funds. They began to be widely used in obstetric and pediatric therapy. Phenibut is prescribed to children for stuttering, enuresis, and nervous tics. It alleviates the condition of women with menopausal syndrome and vegetative-vascular dystonia, which is manifested by pain or dizziness, tachycardia, inadequate and unstable expression of emotions.

Indications for use of Phenibut for adults include:

• Fatigue, chronic fatigue syndrome;
• Difficulty falling asleep, inability to sleep for the required time, interruption of sleep;
• Various neurotic disorders;
• Alcohol withdrawal state (as part of therapy);
• Meniere's disease;
• Vestibular dysfunction;
• Before surgery;
• Prevention of motion sickness in transport.

In positive reviews, patients note that phenibut allows them to feel calmer, more confident, twitching and trembling of the limbs stops, muscles relax and pain caused by their increased tone goes away. For many, the drug allowed them to restore their appetite and regain interest in life.

Advice! Phenibut is a drug with its own specifics and administration characteristics that should not be taken to avoid anxiety during an exam or after a difficult conversation with your superiors.

Before purchasing Phenibut, you need to visit a doctor, since only a qualified neurologist can draw up an individual adequate treatment regimen and choose a drug.

Important information: Indap for pressure: how to take, instructions

Pharmacological properties of the drug Phenibut

Phenibut is classified as a nootropic drug.

The mechanism of action of the drug is reduced to the following areas:

1. Improves the condition of neurons.
2. Activates plastic processes in the central nervous system.
3. Activates synaptic interactions.
4. Improves glucose processing.
5. Increases the level of resistance of nerve cells to irritating factors, prevents the destruction of cell membranes.
6. Accelerates the release of serotonin.
7. Activates the synthesis of ATP, which is a universal source of energy in the body.
8. Reduces the need of cells for oxygen during hypoxia.
9. Protects nerve cells from the destructive effects of free radicals, slows down the processes of membrane peroxidation.
10. Improves cerebral circulation and microcirculation in eye tissues.

Thanks to this action, the medication has the following range of therapeutic effects:

• Activates brain functioning.
• Improves the quality of memory and learning ability.
• Activates attention.
• Stimulates interest in the world around us and initiative.
• Brings a feeling of vigor, relieves lethargy, apathy, and inertia.
• Improves mental clarity.
• Increases stress resistance.
• Has an antidepressant effect.
• Calms, reduces the level of irritability, tension and emotional excitability.
• Relieves increased anxiety, worry, and fear.
• Helps in the treatment of stuttering.
• Improves sleep, promotes falling asleep quickly.
• Helps get rid of headaches.
• Reduces blood glucose concentration.
• Activates the release of growth and joy hormones.
• Promotes the formation and renewal of structural parts of cells.
• Antioxidant effect: accelerates the removal of toxins and free radicals from the body, protects cells from their destructive effects.
• Helps strengthen the immune system.

Phenibut also neutralizes the inhibitory effects of alcohol and alcoholic beverages on the nervous system, increases the activity of mental and intellectual work in older people, without inhibiting the functions of the central nervous system.

The medicine improves bioenergetic processes in the brain after suffering severe traumatic brain injury.

Composition and release form

The active element of the drug is phenibut. One tablet contains 250 mg of this component. Complementary:

• Microcellulose.
• Calcium stearate.
• Silica.
• Sodium carboxymethyl starch.

The medicine is produced in the form of tablets. They are round in shape and white in color (a slight yellowish tint is possible). On one side there is a dosing chamfer.

Duration of action

The drug is quickly and easily absorbed by the body. Begins to act in approximately 30-60 minutes. The period of action of one pill is 4-6 hours.

Phenibut for hypertension

The ability of Phenibut to reduce blood pressure is not specified in the instructions for the drug. Hypertension is not listed among the indications for the use of this drug. And yet, if the pressure rises against the background of emotional experiences, nervous overstrain, the calming effect of Phenibut will come in handy.

Increased emotional stress leads to depression. The revealed prevalence of depressive disorders in hypertensive patients is more than 50%. In a combination of pathologies - hypertension and depression - it is not always possible to identify which of them is the cause and which is the consequence.

Among the factors responsible for high tonometer readings, one of the first places is occupied by prolonged stress, which creates favorable conditions for the progression of hypertension. And hypertension, in turn, is accompanied by headaches, sleep disturbances, and states of anxiety and irritation. Phenibut copes with these symptoms, improving the patient’s condition. The ability of the drug to positively influence the rheological parameters of the blood, activate its circulation and relax the blood vessels leads to normalization of blood pressure. In addition, it inhibits the aggregation of blood clots, thereby preventing clogging of the lumen of blood vessels as a result of their accumulation on the walls. It is successfully used in the complex treatment of complications of hypertension such as stroke and glaucoma.

Numerous studies confirm that the combination of antihypertensive and antidepressant drugs can simultaneously eliminate the symptoms of depression and control blood pressure levels.

Effect on blood pressure

One of the first questions that patients ask when prescribed is whether Phenibut lowers blood pressure or whether it increases blood pressure. It is worth drawing the reader's attention to the fact that this information is completely absent from the instructions for the medicine. And it is impossible to say exactly how the drug will behave when used by a patient.

Medical practitioners note that it has a beneficial effect on blood pressure.

If the increased numbers are caused by stress or nervous tension, then Phenibut is the first emergency aid that will quickly restore the strength of the human body.

Emotions, both negative and positive, can have a bad effect on the body as a whole. Often, against this background, the patient develops depression, from which it is not so easy to get out. Both stress and high blood pressure require mandatory treatment, since both conditions pose a direct threat to human health.

External factors that cause stress lead to increased blood pressure, which provokes headaches, sleep disturbances, irritation and an internal feeling of anxiety. If all of the above factors are present, then Phenibut will quickly and efficiently cope with the task of lowering blood pressure.

Hypertension causes complications, the most dangerous being stroke. The drug allows you to gently restore the body and prevent the deterioration of a person’s condition, avoiding severe complications.

They note that by using the medicine, you can get rid of signs of depression and restore blood pressure levels.

In addition to the fact that a person may have high blood pressure, there are also cases when it is quite low. This is called hypotension. In this case, it is also possible to prescribe the drug. But it is worth paying attention, since Phenibut causes a decrease in blood pressure - even by using a small dose, you can reduce it even more.

According to statistical data, it has been established that the drug does indeed reduce blood pressure, but only with long-term use.

Phenibut for hypotension

Systematic use of Phenibut for hypotension requires increased caution, since already low blood pressure can drop even further, causing fainting. If necessary, a single dose of the drug should be limited to a minimum dose. It has been established that Phenibut lowers blood pressure in case of overdose, as well as with long-term use.

Hypotension often accompanies vegetative-vascular dystonia. In addition to nausea, headaches and fainting, this disease provokes panic attacks. In such cases, the doctor may prescribe Phenibut to alleviate the condition. Providing a quick effect, the tablets do not cause drowsiness or apathy and are well tolerated by the patient. But in some cases there is a decrease in blood pressure, which sharply increases when the drug is discontinued. If such side effects occur, the doctor will discontinue the drug, replacing it with another sedative that is more suitable for the particular patient.

How does Phenibut affect the heart muscle?

European scientists found out whether Phenibut affects the heart and what are the characteristics of this effect. In the course of a number of studies of the characteristics of the effects of nootropics on the cardiovascular system, it was found that the medicine has a beneficial effect on the organ:

1. Protects cells from the destructive effects of toxins and free radicals.
2. Promotes renewal of cellular structures.
3. The calming effect promotes better relaxation of the heart muscle during diastole and complete enrichment of the organ with blood.
4. Protects the heart from overstrain due to stress factors.

It has been scientifically proven that the drug reduces the risk of myocardial infarction.

How to take correctly

The dosage of the drug and the duration of its use are determined by the disease and the severity of clinical symptoms.

Important! Self-treatment with Phenibut can lead to serious consequences. The specificity of the action of a drug that combines the properties of a nootropic and a mild tranquilizer requires careful calculation of doses, compliance with the duration of courses and intervals between them, as well as the time of administration during the day. Some are prescribed to take them in the morning and lunchtime, while others take the pills in the evening.

The age of the patient also matters. The maximum single dosage is 750 mg or 3 tablets, but for older people it is not recommended to take more than 2 tablets at a time.

As a rule, 1-2 tablets are prescribed per dose, 2-3 times a day. The course will depend on how quickly the condition normalizes, and can be two weeks or a month. Repetition is possible with a break of the same duration as the course of treatment.

To reduce blood pressure and improve the functioning of the vestibular system, and get rid of dizziness, Phenibut is taken for 12 days, one tablet 3 times a day.

For children, the powder form is used as it is easier to distribute into doses. Depending on the weight and age of the child, 20-150 mg to 250 mg are prescribed 3 times a day, the maximum possible daily dose is 150-300 mg.

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To obtain positive results, you should follow the general rules of treatment with the drug:

• take only after meals, do not crush and drink with plenty of water;
• start the course immediately with the full dosage, complete treatment gradually, reducing the dose in the last 1-2 weeks of the course by half a tablet every three days until complete withdrawal;
• Be careful with gastrointestinal ulcers; if pain occurs in the stomach, reduce the dosage;
• during long-term therapy, monitor blood for eosinophils, liver condition and blood pressure;
• using a combination of Phenibut with psychotropic drugs, reduce the dosage of both drugs;
• cannot be combined with alcohol and drugs that have a negative effect on the liver and blood;
• During treatment, you must refrain from driving a car and performing work with moving mechanisms that require increased attention.

On a note! To prevent motion sickness while traveling, take 1 Phenibut tablet half an hour before the start. Taking it on the go will be useless if symptoms have already appeared.

Dosage regimen for various conditions

Phenibut is often prescribed to complete the full course of treatment, which can last from 2 to 6 weeks. It is rarely recommended to use for a one-time case (attack, excitement, motion sickness). Drink with water after meals. The tablet must not be crushed or chewed.

The duration of the course of treatment is determined at an appointment with a specialist individually for a particular patient.

The amount of dosage depends on the diagnosis and general condition of the body:

• In the presence of neuroses and anxiety conditions, drink 0.25-0.5 g of the drug 3 times a day. You should not consume more than 0.75 g per day. This dosage regimen is for lowering blood pressure with increased emotionality.
• Children (8-14 years old) with vegetative-vascular dystonia, stuttering, nervous tics, enuresis are recommended to take no more than 1 tablet (0.25 g) per day. After 14 years, you can take an adult dosage.
• At the beginning of the course of treatment, people with vestibular pathologies are recommended to take 0.25 g 3 times a day. After long-term use of the drug, one tablet per day.
• For motion sickness, you need to drink 0.25-0.5 g once before the trip.
• Children under 8 years of age are allowed to take no more than 0.15 g of phenibut at a time, preferably in powder form.

Side effects

By following the individual rules of administration prescribed by the attending physician, it is possible to avoid negative manifestations. However, side effects are possible at the beginning of the course:

• weakness and dizziness;
• drowsiness, headache, nausea;
• slow reflexes;
• vision problems.

If symptoms do not subside within the next two days, the drug is not suitable and should be discontinued and medical advice sought to replace it with another drug. For more severe manifestations (respiratory depression, severe tachycardia, sudden drop in pressure), you should immediately contact a medical facility.

Many people are concerned about the issue of addiction to the drug. It is believed that Phenibut does not cause physical dependence in patients. Negative effects during abrupt withdrawal are caused by the specific action of Aminophenylbutyric acid. By supplying certain enzymes that improve metabolism to the brain, it thereby blocks their production. After stopping the intake of substances from the outside, after some time the body will resume their production on its own, and the negative symptoms will stop. No medical intervention is required.

Psychological dependence on Phenibut can develop due to the ease of administration and the effectiveness of its action. Maintaining intervals between courses helps to avoid this.

When is the drug used?

The range of uses of Phenibut is quite extensive due to its positive and targeted effect on the neuropsychological state of a person. Direct indications for prescribing the drug are:

• neuropsychic weakness (asthenia);
• irritability, anxiety;
• insomnia, nightmares;
• headache and dizziness of a psychosomatic nature;
• neuroses, obsessive states;
• stuttering, tic, enuresis;
• withdrawal syndrome, delirium due to chronic alcoholism;
• vegetative-vascular disorders;

Phenibut is taken for vegetative-vascular disorders

• strong anxiety before surgery;
• motion sickness;
• vestibular pathologies after traumatic brain injury, vascular collapse;
• surges in blood pressure against the background of emotional instability;
• decreased mental activity, attention, memory;
• apathy, fatigue, anhedonia.

Phenibut is sometimes used for high blood pressure if it is caused by the listed psychological syndromes. Its effectiveness is due to its effect on the central nervous system and blood circulation in the brain. Good results are observed in older people and children prone to neuroses and depression. It is used exclusively as part of complex treatment or as a one-time rescue remedy in case of a sudden attack.

Self-administration of the drug is prohibited due to an unexpected reaction of the body. The appropriateness of the prescription is determined by a specialist based on complaints and examination of the patient.

Contraindications

Phenibut is a low-toxic substance, is well absorbed from the gastrointestinal tract, does not accumulate in the body and is excreted by the kidneys. The main contraindications are related to individual intolerance to the components.

You also cannot use:

• Pregnant and lactating women;
• Children under eight years old;
• Persons suffering from peptic ulcers and liver failure.

Overdose

In case of overdose, the following pathological signs develop:

• the content of eosinophils in the bloodstream increases;
• kidney function is impaired;
• nausea develops followed by vomiting;
• drowsiness occurs;
• blood pressure decreases greatly;
• Fatty liver degeneration is possible if the dose exceeds 7 g per day.

Phenibut is a low-toxic compound, and therefore only very long treatment with the drug in large doses leads to hepatotoxic disorders.

Overdose

Overdose is treated by gastric lavage and taking enterosorbents - Polysorb, Polyphepan, activated carbon. Subsequently, symptomatic therapy is implemented to help the affected organs restore proper function.

Analogs

The pharmaceutical market provides a wide selection of products of similar composition and action. Here are the most common ones. The following drugs are identical in composition to Phenibut:

• Noofen;
• Anvifen.

If the doctor has prescribed a small dosage of the drug, Anvifen is preferable, as it is available in dosages of 25 mg, 50 mg, 125 mg and 250 mg.

Phenibut analogs for therapeutic action include: Adaptol, Afobazol, Divaza, Selank, Tranquesipam, Phenazepam.

When answering the question whether Phenibut lowers or increases blood pressure, we can definitely answer that it is not an antihypertensive drug, and during the treatment of psychoneuroses, only a slight decrease in blood pressure levels is observed. Patients prone to low blood pressure should exercise caution during long-term use. Among the side effects, pressure surges were sometimes noted, both lower and higher than normal; in these cases, the drug must be replaced with an analogue at the discretion of the attending physician.

Directions for use and dosage

The dose of the medicine is determined by the attending physician.
The dosage is determined only by a competent specialist. It depends on the pathology. The maximum single dose of the drug is 500 mg. The initial dose can be complete and there is no need to gradually increase the dosage. But you need to stop taking the drug slowly. During the first week, take half a tablet every 3 days, and in the second week, take a quarter tablet every 3 days. Patients who abruptly stopped taking Phenibut describe their state of health after withdrawal very negatively. After discontinuation of the drug the following was observed:

• exacerbation of anxiety and panic attacks;
• sudden jumps in blood pressure;
• insomnia;
• other syndromes that the drug helped get rid of.