Does Riboxin increase or decrease blood pressure? Drug review

As a rule, many patients consider proper nutrition a panacea for most diseases. However, even the healthiest foods are not always able to completely replenish the body with the necessary vitamins and minerals.

To correct the situation, the doctor prescribes special vitamin preparations that strengthen the blood vessels of the heart and improve the general condition of the patient with hypertension.

Riboxin is considered the most popular and effective remedy among vitamin-mineral complexes.

1. This drug increases oxygen supply to the heart, thereby normalizing heart rhythm, strengthening the myocardium, and improving blood supply to the coronary vessels.
2. The drug has a beneficial effect on the energy processes occurring in the heart.
3. Riboxin enhances protein synthesis in muscles and increases cell resistance to hypoxia.
4. The drug also lowers blood pressure in hypertension.

The medicine is prescribed if the patient is diagnosed with arrhythmia, coronary heart disease, cirrhosis of the liver, or hepatitis. The so-called heart vitamins are taken at least four times a day for three months.

Information about the drug

Riboxin is a drug that regulates metabolic processes. The drug is prescribed for cardiovascular diseases, hypertension, and heart pathologies. The drug relieves signs of hypoxia, saturates tissues and blood vessels with oxygen.

Release form and packaging

The drug is available in three forms: tablets, capsules, solution for injection. The form of the drug is selected by the doctor depending on the type and severity of the disease. The composition depends on the form of release.

Riboxin anti-pressure tablets are packaged in individual blister cells. Each blister contains 10 tablets. Light yellow tablets have no distinct odor or taste. One package contains 50 tablets.

White gelatin capsules are packaged in individual blister cells. One package contains 50 capsules.

The solution for injection is transparent and packaged in individual glass ampoules. The package contains 10 ampoules with solution.

Each package contains instructions for using Riboxin.

Packaging of Riboxin tablets

Composition of the drug

The main active ingredient, which is present in all forms of release, is inosine. Only the amount of component in the composition and additional substances differ.

Composition of ampoules:

• propylene glycol;
• sodium sulfide;
• caustic soda;
• sodium hypochlorite.

Composition of capsules:

• powdered sugar;
• starch;
• calcium stearate;
• thickener E461;
• purified water;
• glycerol;
• titanium dioxide;
• gelatin;
• sodium dodecyl sulfate.

Composition of tablets:

• thickener E461;
• calcium stearate;
• dextrose;
• potato starch;
• yellow opadry 2;
• PVS;
• titanium dioxide;
• polyethylene glycol;
• talc;
• yellow iron oxide;
• dyes.

Price and terms of sale

Antihypertensive medication is sold in pharmacies without prescription or prescription from the attending physician. The price for Riboxin is 60 rubles.

Storage conditions

The drug must be stored out of the reach of children, in a dark place at room temperature.

The shelf life and storage of the medicine is three years from the date of manufacture. After the expiration date, the product cannot be used; it must be disposed of in accordance with sanitary standards.

All medications should be kept out of the reach of children

Release form

The drug has 3 main forms:

• Tablets - 20 mg of inosine, orange, round, convex on both sides, yellowish inside, may be white. 10 and 50 pieces are packaged in blisters or plastic jars, respectively,
• Capsules - have an elongated shape, in a hard shell, also orange. When you open the capsule, you can see white powder inside. The shell is made of gelatin. The dose and use are exactly the same as the tablets. Packed in blisters of 10 pieces,
• Solution for injection - available in cardboard boxes with compartments, one containing 10 ampoules of 5 or 10 ml. Inside is a colorless transparent liquid.

The drug is packaged in cardboard packs, they must contain an annotation.

Pharmacodynamic properties: increases or decreases blood pressure

The drug is used to treat many diseases. In European countries, Riboxin is not classified as a medicine, but as a dietary supplement.

The action of the main component of inosine is aimed at normalizing the metabolic process in the body.

Pharmacological action of the drug:

• saturates cells with oxygen;
• improves blood circulation;
• normalizes metabolism;
• relieves the consequences of ischemic kidney disease;
• participates in carbohydrate metabolism;
• increases the activity of Krebs cycle enzymes;
• increases heart rate;
• improves metabolism in the myocardium;
• reduces platelet aggregation;
• relieves signs of arrhythmia;
• promotes tissue regeneration;
• reduces blood pressure.

Riboxin is prescribed for arrhythmia and oxygen deficiency. The effect of the medication continues until the components are removed from the body. The drug is intended to relieve the symptomatic manifestations of the disease, so it is prescribed for prevention or in combination with other drugs.

Riboxin is prescribed to patients with high blood pressure in complex therapy or as a single drug. For arterial hypertension, Riboxin lowers blood pressure, has a beneficial effect on blood vessels, and relaxes diastole.

Metabolism diagram in the body

Impact on the general condition of the body

The participation of drugs in many metabolic mechanisms affects not only the cardiovascular system.

Riboxin is also used:

for arterial hypotension (stabilization of coronary circulation increases systolic and diastolic levels); for the treatment of hepatitis and cirrhosis of the liver; for muscle hypotension (low muscle tone rises due to the acceleration of anabolic metabolism in muscle tissue); for the treatment of gastritis (positively affects the regeneration of mucosal cells gastrointestinal tissue); to accelerate metabolic processes in muscle tissue and increase endurance in bodybuilding.

Mechanism of action

The drug activates metabolism in the body. Thanks to this, tissues are saturated with oxygen, reducing the risk of developing heart and vascular diseases.

Operating principle:

1. The drug is part of ribonucleic acid. It stimulates the body during oxygen starvation and activates metabolic processes.
2. The medication is an angiotensin-converting enzyme inhibitor. When used, internal processes are launched, which leads to the restoration of blood circulation and improved functioning of the cardiovascular system.
3. Activates the processing of pyruvate, which leads to restoration of cell respiration and reduction of oxygen starvation.
4. Increases the production of nucleotides and the activity of enzyme substances.
5. Activates tissue restoration of the gastrointestinal tract. This leads to a decrease in the degree of platelet clumping and the risk of developing blood vessel blockage with blood clots.

Indications for use

• Complex therapy of cardiac ischemia (pre-infarction conditions, angina pectoris).
• Cardiomyopathies of various origins.
• Rheumatic heart disease, congenital or acquired.
• Atherosclerosis, heart rhythm disturbance.
• Urocoproporphyria (congenital changes in metabolism).
• Liver diseases: cirrhosis, fatty degeneration, hepatitis.
• Liver intoxication due to professional activities, alcoholism or drug overdose.
• Stomach ulcer.
• Rehabilitation course after radiation for cancer.
• Keeping athletes in good shape during long-term training.

What is Riboxin used for?

Riboxin is a widely used drug. The drug is prescribed for the treatment of various cardiovascular diseases, pathologies, and disorders of the circulatory system. Admission reduces the risk of developing hypoxia and improves the general condition of the patient. Riboxin reduces blood pressure, but does not lead to the development of hypotension.

Indications for use of Riboxin:

• heart attack;
• cardiac ischemia;
• disturbances in liver function;
• arrhythmia;
• metabolic disorders of the heart muscle;
• heart defects;
• coronary atherosclerosis;
• porphyria cutanea tarda;
• open angle glaucoma.

Riboxin helps with blood pressure and restores heart rhythm.

Studies have shown that Riboxin helps with gastritis and as an adjuvant in immunotherapy. But the instructions for use do not contain recommendations for prescribing the drug for these diagnoses.

The drug helps with heart problems

Riboxin or Panangin - which is better for the heart

Manufacturer: GEDEON RICHTER (Hungary)
Release form: tablets

Active ingredient: magnesium aspartate, potassium aspartate

Despite the fact that both medications are in different pharmacological groups, they can improve the function and structure of the heart muscle. For myocardial diseases accompanied by potassium and magnesium deficiency, Panangin will be the best for the heart.

The Panangin analogue has a positive effect on heart rhythm, the disturbance of which often accompanies cardiovascular pathology.

Application in sports

Riboxin is often used not only for medicinal purposes, but also in sports. It is used in bodybuilding as a non-steroidal anabolic substance.

Benefits for athletes:

1. Inosine is involved in metabolism, therefore it promotes fat burning and muscle growth.
2. The use of the drug increases endurance, so athletes can train longer and more efficiently.
3. The drug increases oxygen exchange and saturates tissues with oxygen, therefore reducing cardiac load during sports training.

The drug Riboxin is taken a couple of hours before sports. It is often used as a creatine substitute.

Riboxin is a medicinal product, so you cannot decide to take Riboxin for weight loss without a prescription from your doctor, as there is a risk of adverse reactions if the dosage is incorrectly selected.

Pros and cons of the drug

The drug Riboxin is prescribed for the treatment of cardiovascular diseases and oxygen metabolism disorders. Riboxin normalizes blood pressure in case of high blood pressure.

Advantages of the drug Riboxin:

• wide range of applications;
• low price;
• over-the-counter;
• increases endurance and promotes fat burning;
• minimum contraindications;
• minimum of adverse reactions;
• reduces the risk of developing heart disease and other disorders of the body.

Disadvantages of the drug:

• to obtain benefits, you must take the drug several times a day;
• relieves only symptomatic manifestations of the disease, but does not treat the root cause;
• In a number of developed countries, the effectiveness of the drug is questioned.

Pharmacodynamics and pharmacokinetics

Patients often wonder how Riboxin affects blood pressure. In fact, it has no effect on blood pressure levels - that is, it does not lower or increase it.

1. “Riboxin” has a positive effect on the functioning of the heart and blood vessels. In the first stages of the development of hypertension, the medicine helps maintain normal blood pressure levels
2. “Riboxin” delivers oxygen to cells, slows down the formation of blood clots and promotes the resorption of cholesterol plaques in blood vessels.
3. At the molecular level, “Riboxin” ensures tissue respiration throughout the body, activates metabolic processes and stabilizes the work of the heart, increasing its shock power during contractions.
4. “Riboxin” maintains vascular tone and restores damaged tissue.
5. The drug makes it easier to endure physical activity and is effective for diseases associated with vascular disorders. Sometimes “Riboxin” is able to stop the toxic effects of other drugs.

All the useful characteristics of “Riboxin” allow it to cope with hypertension in the first stages of damage. The medicine causes receptors in cells to function correctly.

The drug is well absorbed in the gastrointestinal tract, then processed in the liver and partially excreted by the kidneys.

For whom is it contraindicated?

Using Riboxin for blood pressure is relatively safe, but there are a number of contraindications for use:

• individual intolerance to the drug;
• increased levels of uric acid in the blood;
• renal dysfunction;
• low blood pressure.

Before prescribing medication, the doctor must examine the patient

Riboxin for high blood pressure can be taken during pregnancy or breastfeeding only as prescribed by a doctor, if there is a risk of fetal hypoxia or a threat to the health of the mother. There are no restrictions in the instructions for use of Riboxin when taking it during pregnancy or lactation, but caution should be exercised, since the effect of the components on the child has not been studied.

The components of the blood pressure medication pass through the blood into breast milk and can cause allergies in the baby.

The drug Riboxin for hypertension cannot be prescribed to children, since no studies have been conducted on the safety of the drug for the child’s body.

Adverse drug reactions

The drug Riboxin rarely leads to the development of negative reactions from the functioning of systems and organs.

Possible negative reactions:

• immunity: skin itching, rash, slight increase in temperature at the injection site, swelling of the skin, alveolar edema, anaphylaxis, urticaria;
• heart and blood vessels: hypotension, increased heart rate, headaches, increased sweating, nausea, confusion, fainting;
• metabolism: gout, increased uric acid in the blood;
• other body reactions: weakness, loss of strength, redness of the skin at the injection site.

Combined use with other medications

Riboxin enhances and prolongs the effect of heparin, which is used to slow blood clotting in the treatment of thrombophlebitis, for the prevention of venous thrombosis and early treatment of heart attack.

Possible simultaneous use with cardiac glycosides for a positive inotropic effect and prevention of arrhythmia. Also compatible with furosemide, nitroglycerin, nifedipine and similar drugs prescribed for angina pectoris, hypertension, low peripheral coronary blood flow, weak tone of cellular smooth muscle walls.

There is no data on the incompatibility of simultaneous use with other substances. But when administered by drip or jet, it is contraindicated to mix it with other medications.

In some cases, it has been noted that inosine can cause negative reactions from the cardiovascular and immune systems. Use should be discontinued if the following effects occur with its onset:

• anaphylactic shock;
• skin irritation and itching;
• rash, urticaria;
• tachycardia;
• increased sweating;
• persistent headache;
• sudden dizziness.

When administered by injection, local itching or hyperemic manifestations (excessive overflow of blood vessels) at the injection site are possible.

With latent gout, it can cause an increase in the concentration of uric acid in the circulatory system.

Riboxin overdose

Taking Riboxin under pressure rarely leads to an overdose, since the likelihood of intoxication with the drug is low. Signs of overdose:

• gagging;
• vestibular disorders;
• epigastric pain;
• lowering blood pressure.

If there are signs of an overdose, it is necessary to perform a gastric lavage and call a doctor. The doctor will prescribe symptomatic treatment.

An overdose of Riboxin may cause vestibular disorders.

Pharmacological compatibility

Riboxin for hypertension is taken only as prescribed by the attending physician. Before using the medicine, you must tell your doctor about other medications you are taking.

Interaction of the drug Riboxin for blood pressure with other drugs

Instructions for use and dosage

The drug Riboxin has a short duration of action, so the drug is taken up to three times a day.

The decision to use the drug is made by the attending physician after examining the patient. You should not start taking the drug on your own, as this can lead to the development of adverse reactions. The doctor will prescribe an individual treatment regimen and course duration.

The method of use of the drug Riboxin differs in the form of release. The drug in capsules and tablets is taken according to one scheme, and the injection solution - according to another.

The doctor will prescribe the required dosage of the drug

Use of tablets and capsules

The tablets are taken before meals with a sufficient amount of drinking water. Do not crush, break, crush or chew the tablets. They are accepted in their entirety.

Tablets and capsules are taken in stages. The initial dosage is 600 mg. These are three 200 mg tablets, divided into three doses. Gradually the dosage is increased to 1200 mg. The dosage can be increased three days after the start of therapy. You can take two Riboxin tablets at a time. With a further increase in dose, it is necessary to increase the frequency of administration to 6 times a day.

The duration of the course is 1 month.

Use of injection solution

The initial daily dosage is 200 mg. Riboxin injections are given once a day intravenously by drip. After 7 days of using injections, the dosage can be increased to 400 mg. 2 drop injections are administered per day.

Before using injections, the solution is diluted with saline or 5% glucose.

In case of severe cardiac arrhythmias, injections can be injected into a vein in a jet manner to enhance the effect.

The duration of therapy is determined by the attending physician individually. On average, the course lasts 14 days.

Therapeutic effect

Patients using Riboxin for more than two weeks note the following changes:

• reducing the gap between high systolic and low diastolic pressure levels;
• reduction in the number of changes and surges in blood pressure compared to the period before the start of treatment;
• stabilization of heart rate;
• improving lung function;
• increased appetite and performance;
• elimination of problems of attention, memory, coherent thinking.

Due to the improved blood circulation in the vessels of the neck and head, the drug has a positive effect on the functioning of the brain, normalizes intracranial pressure, and as a result, eliminates dizziness, headaches, and tinnitus.

Patient reviews may be based on the general treatment of hypertension in conjunction with other active ingredients. Therefore, taking the drug requires an individual approach, especially if prescribed for long-term use. You need to start with small single doses of 200 mg, while monitoring changes in blood pressure and general well-being.

General recommendations and special instructions

Before using the blood pressure medication, you should carefully read the instructions for use of Riboxin.

General recommendations:

• when taking a course of Riboxin, it is necessary to monitor uric acid levels; if they increase, you must inform your doctor;
• the doctor may prescribe the drug for impaired renal function if the benefit to the patient outweighs the risk to his health;
• the medication does not affect psychomotor reactions, therefore, with a course of treatment, you can drive a car or do work that requires concentration;
• When taking the drug, you should not drink alcohol, as this may lead to an increased risk of adverse reactions;
• Smoking reduces the effectiveness of the drug, so you need to inform your doctor about your bad habit in advance so that he can adjust the dose.