Ibuprofen – increases or decreases blood pressure, can it be taken for hypertension?


Pharmacological principle of action

To understand whether Ibuprofen lowers or increases blood pressure, you need to study the description of the medication. The drug is a derivative of phenylpropionic acid. The product has a powerful analgesic and antipyretic effect. The basic principle of action is based on the fact that the active substance of the drug inhibits the enzymes of arachidonic acid metabolism. This substance plays a major role in the rapid development of fever, inflammation and pain.

The powerful analgesic effect of Ibuprofen is due to the fact that the drug suppresses the synthesis of prostaglandins, as well as platelet aggregation. The medication reduces the manifestation of morning stiffness and also increases joint mobility. The maximum concentration of the active substance in the blood is reached 45 minutes after administration. The duration of the positive effect depends on the form of the medication used and can vary from 3 to 9 hours.

Absorption of the active components of the drug occurs in the digestive tract in the shortest possible time. A single use ensures the active effect of the medicine for 8 hours. Ibuprofen penetrates into the blood and joints. It is excreted through the kidneys, converted into metabolites.

The medication can be taken by people with diseases of the gastrointestinal tract. The drug belongs to non-steroidal anti-inflammatory and antirheumatic drugs. With the correct dosage, Ibuprofen helps eliminate heat in the body, reduce pain, and also prevent the development of inflammatory processes in the body. The medicine does not cause irritation from the gastrointestinal tract. To combat pain, experts recommend using Ibuprofen in ampoules. We will consider the release forms of the drug below.

Composition and release forms

To figure out whether Ibuprofen increases or decreases blood pressure, you need to study the instructions for the medication and also consult with specialists. The effectiveness of the drug depends on the form of release:

  1. Suspension. The mixture is yellow in color, homogeneous, and has a pleasant citrus aroma. 1 ml contains 20 mg of active substance. Sodium saccharinate, glycerol, citric acid, and sorbitol are used as auxiliary components. The suspension is packaged in 100 ml bottles. The container is packaged in a small cardboard box, which comes with instructions and a small measuring spoon.
  2. Pills. The pills are round, biconvex, and white in color. The active substance is ibuprofen, its concentration is 200 mg. The composition of the drug "Ibuprofen" in tablets also includes auxiliary components: potato starch, magnesium stearate, aerosil, vanillin, beeswax, food gelatin, azorubine dye, magnesium hydroxycarbonate, wheat flour, povidone 25, sucrose, and titanium dioxide. The tablets are packaged in small blisters. One package may contain 10, 20 or 100 pills.
  3. Candles. The composition contains 60 mg of active substance. An auxiliary component is solid fat.
  4. Gel, cream. Contains 50 mg/g active substance. Can be used exclusively for external use. The cream is white, the gel is transparent. They have a specific smell. The gel also contains ethanol, propylene glycol, dimexide, carbomer 940, triethanolamine, neroli and lavender oils, methyl parahydroxybenzoate, purified water, creams - dimethyl sulfoxide, macrogol.

For treatment, the tablet form of the medication is most often used. The product should be stored in a dry place protected from direct sunlight.

Indications for use

Does ibuprofen increase or decrease blood pressure? This is the question most often asked by patients to their physician. Experts note that the medication has a positive effect on the human body only when used correctly. Ibuprofen is used to treat the following diseases:

  1. Fever.
  2. Migraine.
  3. Osteochondrosis.
  4. Arthritis.
  5. Gout.
  6. Toothache.
  7. Myalgia.
  8. Inflammation of the ENT organs.
  9. Adnexitis.

Doctors often prescribe Ibuprofen for colds and flu. The medication helps normalize temperature and eliminate pain.

What is Ibuprofen used for?

The drug is prescribed to patients with the following diseases and symptoms:

  • inflammatory processes of the musculoskeletal system;
  • Gout;
  • to block pain symptoms in different areas of the body;
  • headache and toothache;
  • infectious diseases of the respiratory system;
  • pneumonia;
  • diseases of the pelvic organs.

The medicine in the form of a cream is prescribed for the treatment of bone diseases, muscle injuries and others. The medicine is not recommended in the following cases:

  • intolerance to the active substance;
  • diseases of the digestive system;
  • mixed bronchial asthma;
  • allergies to other non-steroidal drugs;
  • low blood clotting and increased bleeding;
  • diseases of the organs of vision, defects in the visual field, disorders of the optic nerve;
  • deficiency of leukocytes and platelets in the blood;
  • congenital deficiency of potassium in the body;
  • severe kidney and liver diseases;
  • cardiovascular failure;
  • skin diseases, purulent wounds.

Ibuprofen is used extremely rarely for high blood pressure, ulcerative colitis, hearing and vestibular disorders. It turns out that the drug is not contraindicated for hypertension, but still not recommended for use. To find out whether Ibuprofen increases or decreases blood pressure, let’s look at how it affects the cardiovascular system.

Contraindications

The drug should not be used for gastritis and duodenal ulcers, colitis. Ibuprofen is not prescribed to children under 10 years of age. The medication is contraindicated during pregnancy and breastfeeding. The medicine should be taken with extreme caution in case of heart, liver and kidney diseases. Therapy should be carried out under the supervision of a doctor. During treatment you need to stop driving vehicles.

Main contraindications:

  1. Pathology of the optic nerve, impaired color vision.
  2. Individual intolerance to the components of the medication.
  3. Scotoma.
  4. Amblyopia.
  5. Hemophilia.
  6. Gastrointestinal bleeding.
  7. Hypertension.
  8. Swelling.
  9. Enteritis.
  10. Chronic pathologies of the vestibular apparatus.

When using Ibuprofen for flu and colds, you need to remember that the medication only relieves painful symptoms, eliminates inflammation, but does not affect the course of the pathology.

Indications and available contraindications

The drug is recommended for use for:

  • Barro-Lieu syndrome;
  • manifestation of any pain (dental, headache, post-traumatic, neurological);
  • pneumonia;
  • bronchitis;
  • osteochondritis;
  • arthritis;
  • various types of fevers;
  • adexite;
  • diseases of the spine;
  • acute respiratory diseases.

The product is used in combination with medications for the treatment and prevention of ailments caused by inflammation.

But there are pathologies for which the use of drugs of this effect, including Ibuprofen, is completely prohibited:

  • blood pressure surges;
  • heart diseases;
  • stomach and intestinal ulcers, Crohn's disease;
  • congenital hypokalemia;
  • dermatitis, open wounds with pus;
  • allergic reaction to the components included in the composition;
  • liver damage;
  • excessive swelling.

It is not recommended to take the medicine during pregnancy, due to the negative impact on the development of the unborn child. It is also better to stop driving during the appointment and avoid heavy mental stress.

Instructions for use

To understand whether Ibuprofen affects blood pressure, you need to study all the recommendations of the drug manufacturer. The tablets are taken exclusively orally, washed down with plenty of still water. The duration of therapy is determined solely by the doctor, since each case is individual.

Standard treatment regimen:

  1. The standard daily dosage for adults is 600-800 mg of Ibuprofen (two to three tablets). The maximum single dose is 400 mg, daily dose is 1.2 g.
  2. A child 6-12 years old can be given one tablet up to four times a day. The maximum dose is 30 mg/kg per day.

Does Ibuprofen increase or decrease blood pressure? This question interests patients who have been prescribed medication to eliminate pain and inflammation.

Adverse reactions

Most often, the drug is well tolerated by children and adults. Adverse reactions occur only in rare cases:

  1. Heartburn.
  2. Nervousness.
  3. Tachycardia.
  4. Drowsiness.
  5. Flatulence.
  6. Depression.
  7. Migraine.
  8. Bronchospasm.
  9. Hypertension.
  10. Lack of appetite.
  11. Anxiety.
  12. Quincke's edema.
  13. Insomnia.
  14. Rhinitis of allergic origin.
  15. Cystitis.
  16. Vomit.
  17. Itching of the skin, rashes.

The likelihood of adverse reactions increases significantly if the patient has exceeded the permissible dosage. That is why you need to strictly adhere to the prescribed treatment regimen and carefully follow all the instructions of the attending physician.

Exceeding the permissible dosage is fraught with acute abdominal pain, vomiting, and nausea. In such a situation, you definitely need to rinse your stomach and drink a high-quality sorbent. But in most cases the drug is well tolerated. If adverse reactions occur, you should stop using the medicine and consult a doctor.

Side negative effects

A bad effect on the body can manifest itself as a malfunction in many systems and organs of the body:

  • From the digestive system, vomiting, abdominal pain, nausea, constipation, dry mouth, and pancreatitis are possible. In rare cases, bleeding occurs.
  • The sense organs may suffer, a decrease in the quality of hearing and vision, scotoma, and allergic genesis may occur.
  • Changes may also occur in the nervous system. Drowsiness, unreasonable irritability, hallucinations, dry eyes and swelling, tinnitus, nervousness and depression appear.
  • Increased blood pressure, tachycardia, deterioration of blood clotting, and difficulty breathing were detected in the cardiac vascular system.
  • Signs of allergies often appear, such as itching, runny nose, anaphylactic shock, fever, and the appearance of urticaria is possible.
  • Negative reactions from the genitourinary system may occur. The amount of urine excreted greatly decreases or blood appears, cystitis appears.

If these effects are detected, you should stop using the drug or reduce the selected dosage and thoroughly rinse the stomach with as much liquid as possible using a sorbent.

The dosage and optimal treatment are selected exclusively by the doctor. Self-medication leads to a lack of the expected effect from the use of the drug and in certain cases can provoke premature death. But, in general, the medicine is well tolerated by the body and is an excellent tool for reducing pain.

Ibuprofen for high blood pressure

Can hypertensive patients use the drug? This is one of the most common questions among patients. The medication is intended to effectively combat various pain syndromes: headaches, toothaches, spasms. But the drug can also affect blood pressure as a result of an adverse reaction. The patient may observe swelling of the limbs, which is caused by fluid retention in the body. Because of this, blood pressure rises and the load on the heart increases. The drug is used with caution in case of impaired liver function. Otherwise, hypertension may occur.

Thus, the drug increases blood pressure, and people with hypertension should take it with caution.

Ibuprofen increases or decreases blood pressure

People who have suffered from hypertension for a long period of time should be well aware that even an anti-inflammatory or antipyretic drug (which is Ibuprofen) can significantly affect the results of blood pressure measurements.

Ignoring this kind of facts can lead to excessively high or low blood pressure.

In particular, medical experiments carried out on Ibuprofen revealed a slight increase in blood pressure when taking the pharmaceutical drug. This can to some extent be explained by its blocking of the clinically significant effects of other compounds and agents. So, Ibuprofen affects hemodynamic processes, but neither hypotension nor hypertension is included in the direct indications for the use of this drug. Although it does not directly affect in any way, it can influence the effectiveness of other drugs, and this must be taken into account when selecting a general clinical regimen.

Available analogues

To figure out whether you can take Ibuprofen with low blood pressure, you need to consult a therapist. You can purchase the medication at any pharmacy without a prescription form. The shelf life of the drug is three years. The gel and suspension are suitable for use only for two years. If Ibuprofen is not available in the pharmacy or the patient is intolerant to the components of the medication, then you can purchase available analogues:

  1. Advil.
  2. "Ibuprom".
  3. "Deblok."
  4. "Pedea."
  5. "Iprene."
  6. "Artrockam".
  7. "Ibufen."

It is strictly forbidden to independently choose a suitable analogue to replace Ibuprofen, since a preliminary consultation with a doctor is required.

Analogs

Due to many contraindications, negative effects on the liver and cardiovascular system, it is better for patients to use analogues of Ibuprofen. Taking medications without a doctor's prescription is prohibited so as not to cause irreparable harm to the body. You can replace the medicine with Ibuprom, Imet, Nurofen, Brufen, Ibufen and Paracetamol. And also, you can choose the most suitable release form individually.

The following are currently recognized as an adequate replacement for Ibuprofen:

  1. Arviprox.
  2. Ibuklin.
  3. Arofen.
  4. No pain.
  5. Bofen.

The list of possible analogues is quite large, but a replacement should be selected by the attending physician, who will be well aware of the peculiarities of your body’s reaction.

Use of Ibuprofen tablets during pregnancy

The release forms of the drug allow each patient to choose the appropriate version of the drug. It is strictly forbidden to take Ibuprofen from the 28th to the 40th week of pregnancy. The use of the medication is permissible only in the first and second trimester, but after excluding the possibility of developing adverse reactions. Otherwise, there is a high risk that the drug will provoke the development of pathology in a male fetus. Doctors note that the likelihood of cryptorchidism increases 16 times. If high-quality therapy is needed during the lactation period, then the child is switched to feeding with special artificial formulas. The medicine can be used parenterally.

Detailed information is presented in the video.

Treatment of children with Ibuprofen

The drug should be given only on the recommendation of a pediatrician. Before prescribing the medicine, the doctor must thoroughly examine the child. The entire course of therapy must be carried out under the strict supervision of a physician. In pediatrics, suspension and suppositories are used from three months. Tablets are prescribed to children from the age of six. The maximum daily dosage is 800 mg (four tablets). The interval between taking tablets should be at least six hours. Ibuprofen in ointment form can only be used by adult patients. The drug can be given to the child only after meals. Thanks to this, you can reduce the likelihood of developing adverse reactions. The duration of treatment depends on the clinical picture. For example, to combat fever, three weeks of therapy are prescribed.

How to use Ibuprofen?

Depending on the form of release, the medicine is used with food, intravenously and rectally. Ointments and gels with such an active substance are used externally. They are applied to diseased areas 2-3 times a day. Ibuprofen in the form of suppositories is often used for children, the amount depending on the weight and age of the child. Tablets are prescribed three to four times a day, 200-400 mg of the active substance. If you miss taking a pill, it is not recommended to increase the dosage.

As a rule, Ibuprofen is prescribed in short courses. In case of long-term therapy, constant monitoring of the functioning of the kidneys and liver is required. The drug is rarely prescribed to older people and those who suffer from diseases of the gastrointestinal tract. Patients with hypertension take the medicine with constant monitoring of body weight, blood pressure and daily urine output.

The drug can impair vision, so such patients are not recommended to take it. Taking Ibuprofen with alcohol is prohibited. The drug in the form of an ointment should be used carefully to avoid getting into the mouth and eyes.

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