Composition, release form
The drug is sold in pharmacies under the trade name "Askofen". Its non-proprietary international name is “ACETYLSALICYLIC ACID; PARACETAMOL; CAFFEINE."
Each tablet contains 3 active components:
- paracetamol (200 mg);
- caffeine (40 mg);
- acetylsalicylic acid (200 mg).
The excipients contained in the medication include the following:
- talc;
- povidone;
- Vaseline oil;
- stearic acid;
- potato starch;
- silicone emulsion;
- calcium stearate.
The drug is produced in the form of tablets. They have a light shade (white, cream) and a flat-cylindrical shape. There is no particular smell. The medication package contains 10 tablets.
Important nuances
Despite everything, experts categorically insist that systematically combating low blood pressure with Askofen or just caffeine can harm the body. As an alternative, they recommend drinking tea for two weeks with the addition of tinctures of Eleutherococcus or ginseng, the effect of which is aimed at strengthening the overall immune system, which, as a result, gives a certain result in terms of increasing the vital activity of hypotensive patients.
Of course, this is not the only method of solving the problem. Doctors recommend drinking plenty of fluids regularly, following a balanced diet and leading an active lifestyle. Also, the first priority should be to maintain the necessary sleep time, eliminate bad habits and get enough fresh rest.
Is it gloomy outside, causing pressure drops and headaches? Askofen will relieve pain, and the caffeine it contains will improve your overall condition.
How does Askofen affect the body - does it increase or decrease blood pressure?
Askofen is a drug that is recommended as an antipyretic and analgesic. The drug contains three active components:
- Caffeine, 40 mg. Dilates blood vessels, reduces drowsiness and fatigue, significantly increases physical and mental performance, and tones brain vessels. Strengthens the effect of other components.
- Paracetamol, 200 mg. Has an active analgesic and antipyretic effect.
- Acetylsalicylic acid, 200 mg. It has pronounced analgesic, antipyretic and anti-inflammatory properties.
The drug Askofen in tablets is taken for fever, headaches, toothaches, neuralgia, myalgia, rheumatism, migraines.
Pharmacological action, pharmacodynamics, pharmacokinetics
"Askofen" is considered a combination drug, its action is provided by each of the active components:
- paracetamol has an analgesic, anti-inflammatory, antipyretic effect;
- caffeine helps dilate the blood vessels of the heart, muscles, and kidneys. At the same time, it constricts the blood vessels of the brain and digestive organs. This component increases the reflex excitability of the spinal cord, excitation of the respiratory and vasomotor functions. Caffeine eliminates drowsiness, fatigue, and significantly increases performance;
- acetylsalicylic acid eliminates pain, relieves inflammation, reduces the risk of developing blood clots, and regulates the synthesis of prostaglandins.
The tablets are intended for oral administration. When using the tablets in question, about 90% of the drug is absorbed. The effect of the active components on the site of pathology begins a quarter of an hour after taking a single dose.
The medication in question is used for arterial hypotension because caffeine, which is one of its components, improves the condition of hypotension and eliminates some of its symptoms, such as headache, weakness, drowsiness, and decreased performance. The drug constricts the blood vessels of the brain and gives a boost of energy. Therefore, many patients consider Askofen a medicine for low blood pressure.
Patients often ask whether Askofen increases or decreases blood pressure. They started taking the hypotensive drug in question to increase blood pressure on their own, without instructions, for the reason that the medication contains caffeine. But Askofen should be used once when lowering blood pressure. The drug should not be used as part of a basic treatment regimen for hypotension.
The time to reach the maximum concentration of the substance in the serum differs for each active component:
- paracetamol – about an hour;
- acetylsalicylic acid – about 1 – 2 hours;
- caffeine – about 2.5 hours.
About 80% of the acids of the active substances are excreted through the kidneys.
General information about the drug
The combination of active components of the drug provides an effective analgesic effect. Active substances reduce exudation, as well as swelling and redness in the area where the inflammatory process is localized. The components increase the speed of blood flow to the area of inflammation, which improves the supply of oxygen ions and beneficial elements and helps to quickly eliminate painful symptoms. The drug has the following effects on the body:
- anti-inflammatory with reduction in temperature and heat;
- pain reliever;
- antiaggregation.
The medication increases the pain threshold, affects thermoregulation receptors, reduces temperature, and changes occur in the hemostasis system and in the process of aggregation of platelet molecules (prothrombin time is extended).
Askofen is prescribed for the following diseases:
- headache, dental menstrual pain of moderate severity;
- arthritis, rheumatism, pericarditis, chorea of rheumatoid type;
- osteoarthritis, osteochondrosis, lumbago and sciatica;
- myalgia, arthralgia and neuralgia;
- inflammatory processes during influenza, acute respiratory infections.
Indications for use
Askofen tablets have an effect similar to the familiar aspirin. They provide a moderate analgesic effect and stabilize the temperature. The drug helps reduce the severity of anxiety symptoms in various diseases. The medication is especially effective in suppressing severe pain of various etiologies, as well as inflammation.
The main purpose of the medication in question is to eliminate pain. Doctors prescribe these tablets for the treatment of various diseases. Let us indicate what Askofen helps with:
- colds accompanied by fever;
- radicular syndrome of the lumbar, cervical, thoracic regions;
- severe toothache;
- pain syndrome during menstruation.
Indications for the use of "Askofen" are represented by the following pathologies:
- myalgia;
- pain of unknown etiology;
- neuralgia;
- pain in muscles and joints;
- increased frequency of migraine attacks;
- rheumatic pains;
- algodismenorrhea;
- headache;
- peripheral nerve damage;
- lumbago, thoracic radicular syndrome;
- toothaches.
Effect on pressure
Askofen is capable of both increasing blood pressure and decreasing it. It all depends on the individual characteristics of the person. The tablets contain several components that have different effects on the body.
Acetylsalicylic acid dilates blood vessels, accelerates the blood, blocks the level of prostaglandins, which leads to a decrease in blood pressure. And the presence of caffeine provokes a surge of strength, energy and vigor, helps to increase the tone of the vascular walls, as a result of which the pressure begins to increase.
Therefore, it is impossible to say for sure whether Askofen can be taken at low or high blood pressure. But in any case, this remedy is not recognized for the treatment of hypotension and hypertension. Its use is recommended only for the purpose of eliminating pain and normalizing body temperature.
If you need to take this medication, you should first consult your doctor. It is unknown how the body will react to the drug. A person with an unstable blood pressure level may develop a hypertensive or hypotensive crisis after taking it.
Contraindications
"Askofen" should be used according to the indications of a specialist with strict adherence to the dosage. Superficial self-medication poses a health risk. The instructions contain contraindications for taking the medication, which must be taken into account when starting a therapeutic course using the medication in question.
Medical restrictions on the use of the drug include:
- aortic aneurysm;
- chronic damage to the liver and kidneys;
- stomach ulcer;
- the patient’s tendency to develop erosion and bleeding of the digestive tract;
- hemorrhagic diathesis;
- portal hypertension;
- progressive glaucoma;
- asthma, which was provoked by the use of acetylsalicylic acid;
- deficiency of glucose-6-phosphate hydrogenase;
- children's age (up to 15 years);
- nervous disorders;
- intolerance to the active components of the drug;
- pregnancy and lactation;
- cardiac ischemia.
Does Ascofen increase or decrease blood pressure?
Askofen is a well-known medicine that comes in the form of white tablets and is widely used as a means to reduce fever and relieve pain.
The drug is mainly prescribed for painful conditions, migraine, neuralgia, myalgia, rheumatism, dysmenorrhea, headache, joint and other pain.
This drug is very affordable and can be purchased at a pharmacy without a prescription.
The effect of Askofen on blood pressure
People often use Askofen for blood pressure. Askofen only helps people who have problems with low blood pressure.
Many people prefer to use the drug during temperature changes, sudden changes in weather, or low atmospheric pressure.
After taking Askofen, they note a decrease in the unpleasant manifestations of the disease, feelings of fatigue, heaviness and dizziness. Does Askofen really increase blood pressure, at what pressure should it not be taken?
Askofen tablets are used as an analgesic and antipyretic drug for toothache, headaches and to normalize blood pressure.
Composition of the drug
The drug directly affects the reduction of inflammatory processes in the body. This is facilitated by the active components in its composition:
- caffeine, which helps enhance the action of other elements and dilate blood vessels. Due to this, lethargy and weakness disappear, a person feels a surge of strength, as well as physical, mental and emotional activity. Askofen helps people with low blood pressure thanks to caffeine; it can easily raise blood pressure by 10–15 units. If you suffer from hypertension, this drug is contraindicated if you have high blood pressure, as this can lead to complications;
- “Paracetamol”, which quickly relieves fever and reduces pain;
- acetylsalicylic acid, which has a significant analgesic, antipyretic and anti-inflammatory effect.
The drug has this name due to its components: Askofen-p, “Ac” refers to acetisalicylic acid, “cofen” refers to caffeine, “p” refers to Paracetomol.
In addition to the named active ingredients, the medicine contains excipients.
Many people use Askofen as a medicine to normalize blood pressure, but the instructions do not indicate anything about its indications and dosage in this case.
Instructions for use
One tablet of "Ascophen" should be taken 2-3 times a day after meals, the medicine should be washed down with a glass of water to reduce irritation of the gastrointestinal tract. Typically, the course of treatment is about a week.
For severe pain, it is recommended to take 2 tablets at a time, but keep in mind that the maximum you can take is only 6 tablets per day.
Between taking Askofen tablets, you must take a break of at least 4 hours, and if you have problems with the kidneys or liver, 6 hours.
If you are using the drug to relieve any pain syndrome, you should not take it for more than 5 days in a row; to reduce fever - for more than 3 days. Your doctor may suggest other doses and dosage regimens for the drug.
Indications for use
Adults are recommended to use the medicine to relieve mild to moderate pain. "Askofen" helps with:
- headache, migraine;
- toothache;
- muscle pain;
- joint pain;
- pain during menstruation;
- neuralgia and other pain syndromes.
According to numerous statements, after taking it, people’s performance increases and fatigue disappears.
Doctors advise using Askofen for low blood pressure. Adults and children over 15 years of age can use Askofen only for the treatment of colds, acute respiratory infections and other diseases in order to reduce fever. Taking the drug by children under 15 years of age is strictly prohibited.
Contraindications
The following processes are contraindications to the use of Askofen:
- high sensitivity to medicinal components and other substances in its composition;
- exacerbation of ulcers;
- gastrointestinal bleeding;
- renal failure;
- liver failure;
- asthma;
- glaucoma.
If you have consumed alcoholic beverages, it is strictly forbidden to take Askofen after this, since the risk of developing toxic liver damage increases significantly.
If you have high blood pressure, you should stop taking the medicine.
During pregnancy and lactation
When a woman is expecting a child or is breastfeeding, she is contraindicated to use Askofen.
It is indicated that only in the second trimester of pregnancy a single use of this medicine is permitted, provided that the benefit to the mother is significantly higher than the risk to the child.
In the first and third trimester, using the medicine can lead to dire consequences for the child. We include here cleft palate (cleft lip, cleft palate), delayed labor and various other problems.
If a woman needs to take the drug during breastfeeding, she should stop breastfeeding. The components of the drug can pass into breast milk and harm the baby and increase the likelihood of bleeding.
Drug interactions
The active components of the drug enhance the absorption of certain medications. These include:
- hormones that regulate vital processes (steroid);
- indirect anticoagulants;
- reserpine;
- heparin;
- hypoglycemic agents.
"Askofen" helps to weaken a number of drugs:
- "Spironolactone";
- "Furosemide";
- antihypertensive drugs and others.
Originally posted 2017-06-12 14:30:24.
Does “Nise” increase or decrease blood pressure?
Source: https://poddavleniem.ru/lekarstva/askofen-ponizhaet-ili-ponizhaet-davlenie.html
Instructions for use
The tablets in question are prescribed for therapy in adolescents and adult patients. In any case, the patient must follow the daily dosages indicated in the instructions to avoid accidental overdose. Due to the fact that taking Askofen can cause disruption of the functioning of the gastrointestinal tract, the tablets should be taken after meals. Doctors recommend drinking the drug with plenty of alkaline, carbonated water, and milk.
Adults can take 1–2 tablets, leaving a 4-hour break between doses. The maximum permissible dosage per day is 6 tablets. To relieve acute pain, it is enough to drink 2 tablets at a time.
The duration of the therapeutic course differs depending on the severity and course of the disease. The duration of use should not exceed 5 days if the medicine is prescribed for pain relief. If the medication is prescribed as an antipyretic, the duration of the course of treatment should not exceed 3 days.
The annotation for “Askofen” does not contain clear instructions about the dosage in which it reduces blood pressure or, on the contrary, increases it, but at the same time, due to the caffeine content in the drug, it should be taken with caution by those who suffer from arterial hypertension (high blood pressure).
Video on the topic
A few more interesting facts about the effect of Askofen on blood pressure:
Hypotonic patients can use Askofen without any risk if pain occurs or body temperature increases. In most cases, the drug helps not only relieve pain and fever, but also tone up, which is especially important for low blood pressure. For hypertension, Askofen can be used, but with the permission of the attending physician. Self-use of the drug may cause unpleasant consequences.
Askofen increases blood pressure slightly. This is indicated in the list of side effects in the official instructions for the medicine. Before you start taking any drug, we strongly recommend that you consult your doctor.
The information on the MyMedNews.ru website is for reference and general information, collected from publicly available sources and cannot serve as a basis for making a decision on the use of medications in the course of treatment.
MyMedNews.ru
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Side effects
During intensive therapy with the drug in question, the patient may experience discomfort. Doctors explain their occurrence by a period of adaptation of the drug in a weakened body. The side effects that occur when taking tablets are not local. They can manifest themselves in various internal organs and systems.
Important: The occurrence of any side effects requires temporary cessation of use of the tablets. Additional consultation with your doctor is required.
The following side effects must be indicated:
- in the area of the gastrointestinal tract organs, gastrointestinal bleeding, symptoms of dyspepsia, vomiting, diarrhea, renal and liver failure may appear;
- in the area of the cardiovascular system, tachycardia, arterial hypertension, arrhythmia, and nausea appear;
- in the area of the nervous system, depression, drowsiness, dizziness, and confusion are observed;
- Quincke's edema, local allergic reactions, bronchospasm, and anaphylactic shock occur on the skin.
Experts do not recommend using the medication in question for a long period. They explain this by the fact that it can provoke the development of chronic diseases (deafness, Stevens-Johnson syndrome, tinnitus, decreased platelet aggregation, blindness, hypocoagulation, hemorrhagic syndrome).
Side effects after Askofen
Side effects after using Askofen as a medicine:
- May lower blood pressure.
- Diarrhea.
- Pain in the heart area.
- Headache.
- Hypocoagulation.
- Nausea.
- Sleep disorders.
- Cardiopalmus.
- Noise in ears.
- Vomit.
- Dizziness.
In case of overdose, various side effects occur. If such a situation occurs, you should immediately call an ambulance.
Askofen is not intended to increase blood pressure in hypotensive patients. To normalize blood pressure, first of all, you need to see a doctor so that he can prescribe therapy and medications that you can take in critical situations. This is the only way to feel good all the time and not feel a drop in blood pressure throughout the day. Self-medication with medications rarely leads to positive results, but only temporarily relieves the symptoms of the disease.
Overdose
Exceeding the dose of Askofen indicated in the instructions may cause an overdose. Its signs are:
- paleness of the skin;
- nausea, vomiting;
- sweating;
- pain in the gastrointestinal tract;
- tinnitus;
- tachycardia;
- bronchospasm;
- collapse;
- drowsiness;
- breathing problems;
- convulsive state.
If signs of poisoning with this drug appear, you should urgently call an ambulance. Usually the victim’s stomach is washed and allowed to take adsorbents.
Adverse reactions and overdose
Askofen is usually well tolerated, especially when taken as a single tablet for pain relief.
Prolonged and uncontrolled use can lead to undesirable reactions, which manifest themselves:
- heart rhythm disturbances;
- increased blood pressure;
- pain in the heart;
- bleeding;
Askofen, like any other medication, can have negative effects on the body
- headache;
- anxiety, agitation, insomnia;
- tremor of the limbs;
- ringing in the ears;
- dyspeptic disorders (vomiting, nausea, diarrhea);
- inflammation of the gastrointestinal tract;
- skin rashes;
- hypoglycemia (low blood sugar);
- bronchospasm;
- anaphylaxis, angioedema.
Interaction with other drugs
When prescribing a specific complex therapy regimen, a specialist must take into account certain limitations. It is important to know the specifics of drug interactions between Askofen-P and other medications, because the active components of other drugs can disrupt the therapeutic effect of certain pharmacological groups.
You need to know these types of interactions:
- "Askofen" enhances the effect of indirect coagulants, reserpine, heparin, steroids, and hypoglycemic drugs.
- The medication in question reduces the effectiveness of antihypertensive drugs, Spironolactone, Furosemide, and anti-gout drugs.
- The use of acetylsalicylic acid provokes the appearance of side effects of such drugs as: non-steroidal anti-inflammatory drugs, corticosteroids, Methotrexate, non-narcotic analgesics, sulfonylurea derivatives.
- You cannot combine Askofen with taking barbiturates, drugs for epilepsy, Zidovudine, Rifampicin.
- Under the influence of caffeine, the absorption of Ergotamine is accelerated, and Metoclopramide promotes the penetration of paracetamol into the systemic bloodstream.
At what pressure is it applied?
The drug has a beneficial effect on the condition of patients with low blood pressure as a result of normalization of blood flow and expansion of the arterial membranes. The drug is not the main drug in normalizing blood pressure, and its main effects are anti-inflammatory and analgesic.
Hypotonic patients who took Askofen for pain relief noted clear improvements in the general condition of the body and a decrease in the symptoms of hypotension. The main indicators of improvement in the condition of hypotension:
increased performance;- reduction in the intensity of headaches and dizziness;
- eliminating nervousness, irritability and anxiety;
- improved mood;
- relieving fatigue, feeling a surge of energy in the body;
- improved vision.
In the drug Askofen P, phenacetin is replaced with paracetamol, which enhances the effects of caffeine and aspirin. The effectiveness of the drug in hypotensive patients is due to the active components in its composition - caffeine and paracetamol. In combination, these 2 components in Askofen increase blood pressure.
When weather conditions change, which is accompanied by joint, muscle and headaches in weather-dependent hypotensive patients, this medication is able to cope with negative symptoms and improve the general condition of the body.
Use during pregnancy
The medication in question is strictly prohibited for pregnant women to take during the first and third trimester. During this period, Askofen can cause an increase in uterine tone.
In the second trimester there are no particularly strict restrictions on the use of the drug. A pregnant woman is allowed to take Askofen tablets only if the benefit to the mother significantly outweighs the likely harm to the fetus.
During breastfeeding, doctors recommend that mothers stop taking this medication. If the doctor prescribes intensive therapy with Askofen, you should stop breastfeeding (temporarily).
Pregnancy and Askofen
The drug is potentially dangerous for pregnant women.
Askofen should not be taken in the first and third trimester, and in the second, only if absolutely necessary, you are allowed to take the medicine, but no more than once.
If you do not follow these recommendations in the first trimester, there is a risk of serious developmental defects in the fetus (in particular, newborn boys may develop abnormalities in the structure of the genital organs in the form of cryptorchidism, and hepatogenic encephalopathy is possible in both sexes).
In the third trimester, the drug can lead to the development of hypertension in the unborn baby, as well as inhibition of the delivery process. Obviously, no expectant mother wishes such problems for her child.
During lactation, the medicine is completely prohibited. The prohibition is immutable, and does not depend on what level of blood pressure is observed in a lactating or pregnant woman.
special instructions
- With prolonged use of the medication in question, its therapeutic effect decreases. In addition, new diseases of the body may develop.
- Carrying out intensive therapy requires monitoring blood pressure, liver and kidney function, and uric acid concentration (this is necessary to prevent gout attacks.
- It is not recommended to use Askofen for therapeutic purposes in childhood.
- If surgery is to be performed, you should temporarily stop taking the medication in question.
- Do not exceed the dosage specified in the instructions.
How to take and at what pressure, dosage
To reduce the irritating effect of ASA on the gastrointestinal mucosa, Askofen is recommended to be taken after meals 2-3 times a day, no more than 2 tablets at a time. The maximum dose is no more than 6 tablets per day.
It is recommended to take the drug with plenty of water.
You need to take the drug with a glass of clean water.
The interval between taking tablets should be at least the half-life (4 hours). If the patient has problems with the liver or kidneys, the interval is increased to 6 hours.
If Askofen is taken as a painkiller, you can take the tablets for no longer than 5 days.
What kind of blood pressure do Askofen tablets help with? The official instructions do not provide for the treatment of low blood pressure with this drug.
To increase blood pressure, it is not recommended to use Askofen constantly. A single dose of the drug is allowed if health deteriorates during weather changes, to which hypotensive patients react with a headache or asthenic condition.
All other regimens for taking Askofen are determined by the doctor.
Analogs
If the patient has contraindications to the use of Askofen, the doctor prescribes another drug. In order not to harm the patient’s health, experts select an analogue that does not have the same contraindications as the medicine in question.
Analogues are also prescribed in the absence of significant improvements or the appearance of new health complaints.
The following drugs have a similar effect:
- "Excedrin";
- "Acifein";
- "Citrapar";
- "Aspirin";
- "Migrenol Extra";
- "Kofitsin plus";
- "Citramarine".
Reviews
People often use the tablets in question to normalize blood pressure. There is no specific dosage in the instructions for using Askofen for hypotension. But people who used it for low blood pressure noted a noticeable increase in ability to work, decreased fatigue, elimination of headaches, absent-mindedness, and weakness from low blood pressure.
Some reviews contain information about Askofen's ability to improve the condition when weather conditions change. Changes in the weather often provoke the following unpleasant sensations:
- lethargy;
- numbness of the limbs;
- Bad mood.
What kind of blood pressure do tablets help with?
Most doctors do not believe that the medication has a strong effect on blood pressure. But many people suffering from hypotension note a positive effect with a sharp decrease in blood pressure. It is not recommended to take Askofen tablets for high blood pressure due to the caffeine content in their composition. Askofen does not lower blood pressure and its use is contraindicated for hypertensive patients, especially regular use. The tablets can cause a hypertensive crisis.
With low blood pressure, the drug helps improve well-being, relieve headaches and dizziness, and cope with weakness and apathy. It should be drunk when the climate changes, since hypotensive people feel especially bad during this period. But the pills are classified as an emergency aid, not a drug. Therefore, it is not recommended to drink it constantly when blood pressure drops. If possible, it is better to stop taking the drug for hypotensive patients.
Instructions for use are included with the package. It lists the dosages of tablets depending on the purpose of use. Askofen for low blood pressure is not always effective, since it is not intended for use by hypotensive patients with low blood pressure. And the spectrum of its action does not cover the stabilization of low blood pressure.
Approximate price in Russia
"Askofen" is often used for hypotension for the reason that it not only alleviates the condition, but is also quite cheap. And buying from an online pharmacy will be even cheaper.
We will indicate the approximate cost of the medicine in different pharmacies in Moscow:
Pharmacy name | Cost of the drug (in rubles) |
"ElixirPharm" | 53 |
"ZdravZona" | 45 |
"Lykitoria" | 60 |
Europharm | 50 |
"Kremlin Pharmacy" | 48 |
"Hippocrates" | 53 |
"City" | 47 |
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Ivan Grekhov
Graduated from the Ural State Medical University with a degree in General Medicine. General practitioner