Pentalgin increases or decreases blood pressure

Description of the medication

"Pentalgin" is available in the form of capsules, which are covered with a green shell. The drug is packaged in special cellular contour blisters of 2, 4, 12 tablets. The outer packaging is made of cardboard. You can purchase the medication at any pharmacy without a doctor's prescription. "Pentalgin" is intended to eliminate pain of various origins. In terms of its effectiveness, this medicine is significantly superior to existing analogues. The correct dosage of the drug allows you to overcome the inflammatory process in the body and normalize the temperature. Indications for use of the Pentalgin tablet can be very different.

Composition of the medicine

Patients regularly ask questions about whether Pentalgin increases or decreases blood pressure. The unique composition of the drug can significantly improve human health. The base contains 6 active components that have a powerful analgesic effect.

The classic composition of the drug "Pentalgin" includes the following substances:

1. Naproxen. The component activates the intensive production of biologically active substances that have a positive effect on the condition of smooth muscles. "Pentalgin" helps eliminate spasms, reduce inflammation and pain.
2. Paracetamol. The antipyretic and analgesic effect is directly related to the positive effect on thermoregulation centers.
3. Caffeine. The substance dilates blood vessels, perfectly tones the body, and also slightly increases blood pressure. Caffeine increases the analgesic effect of the drug several times.
4. Codeine. Reduces sensitivity to pain.
5. Drotaverine hydrochloride. Excellently suppresses muscle spasms of internal organs.
6. Phenobarbital. The component relaxes the patient and significantly enhances the positive effect of the painkillers and anti-inflammatory substances of the medication.

To understand whether Pentalgin increases or decreases blood pressure, you need to study the instructions for the drug. Manufacturers note that the medication can be used for severe pain, which is accompanied by high fever and periodic spasms.

Pentalgin: increases or decreases blood pressure, methods of application

"Pentalgin" is a medicine that has a combined effect. Consists of several active substances. The drug has a wide range of effects on the body: it reduces body temperature, fights inflammation, relieves spasms in smooth muscles and severe pain.

In medical practice, there are various drugs to normalize blood pressure (BP). Does Pentalgin increase or decrease blood pressure? A question to ask your doctor in case of pathological abnormalities. The drug is in demand in modern medicine. Helps improve the patient's condition during the development of various diseases.

Interaction with other drugs

The drug "Pentalgin" consists of a number of active components that help it eliminate painful symptoms. The drug contains:

• Paracetamol. Reduces high body temperature;
• Caffeine. It has the property of dilating blood vessels and increasing brain activity. This component eliminates fatigue and drowsiness. It also increases the effectiveness of the painkillers contained in the drug;
• Pheniramine. Blocks histamine receptors;
• Naproxen. Has an anti-inflammatory effect;
• Drotaverine. Eliminates spasms.

The drug contains caffeine

Many patients are sure that Pentalgin and blood pressure are somehow related to each other. That is, it is assumed that after taking this drug, blood pressure normalizes. In reality, this is not how things happen.

It is difficult to say definitively whether this medication increases blood pressure. Doctors say that it does not have a significant effect on hypotensive patients.

Caffeine, which has hypertensive properties, does not have time to affect blood pressure, since it is leveled out by another component of the drug - drotaverine.

If you have high blood pressure, doctors advise you to stop taking Pentalgin. The drug can cause a jump in upper pressure, which can cause a person’s condition to worsen significantly.

The release form of this medicine is greenish tablets. Packs of 2, 4, 6 or 12 pieces. The medicine consists of 5 active components that are highly effective and have a strong effect:

• Paracetamol. An analgesic that helps reduce body temperature.
• Naproxen. This component has anti-inflammatory properties.
• Caffeine. It has a vasodilating effect and increases brain activity. It also eliminates fatigue and drowsiness.
• Drotaverine. Helps eliminate spasms.
• Pheniramine. Blocks histamine receptors.

Among the excipients are:

• potato starch;
• hyprolose;
• croscarmellose sodium;
• lemon acid;
• magnesium stearate;
• talc;
• yellow dye;
• indigo carmine

Many patients are sure that Pentalgin and blood pressure have a relationship, but this is rather a misconception. With normal and low blood pressure, the drug will not give the desired effect, since caffeine, which has a hypertensive effect, is neutralized by the vasodilating effect of drotaverine.

In case of severe hypertension or high blood pressure, it is not recommended to take the medication, since the pressure can rise sharply to critical levels. The medicine can increase blood pressure only if used uncontrolled, and if the dosage is doubled or tripled. But this should rather be attributed to side effects rather than therapeutic effects.

When taking Pentalgin simultaneously with anti-inflammatory drugs and aminophenanosis, you can notice increased toxicity of both drugs.

1. Coumarin anticoagulants enhance the effect of Pentalgin.
2. The use of rifampicin reduces the effectiveness of the active component of paracetamol.
3. Oral contraceptives, antidepressants, and allopurinol increase the toxicity of metamizole sodium.
4. When Pentalgin is used simultaneously with Codeine, the effect of the drug, which depresses the functioning of the nervous system, is enhanced.
5. The effectiveness of combining Pentalgin with monoamine oxidase inhibitors, antidepressants and codeine also increases.
6. Caffeine reduces the effectiveness of medications that depress the nervous system and enhances the effects of non-steroidal anti-inflammatory drugs.
7. The simultaneous use of Pentalgin and drugs that depress the nervous system, you can notice a doubled effect of phenobarbital.
8. Interaction of Pentalgin with ethanol is prohibited.

In a separate group of patients, side effects were observed during treatment with Pentalgin:

• nausea, vomiting, diarrhea, lack of desire to eat, impaired absorption of nutrients.
• insomnia, loss of strength, slow coordination of movements, migraine, nervousness;
• "Pentalgin" increases blood pressure, it can cause arrhythmia, anemia;
• blurred vision, sensation of tinnitus;
• allergic rashes on the skin.

If side effects occur, stop taking the medicine and consult a doctor. In case of a drug overdose, the following symptoms are observed:

• feeling of nausea, lack of desire to eat;
• pain in the intestinal area;
• bleeding in the stomach;
• increased heart rate;
• increased body temperature;
• convulsions;
• mental disorder;
• panic attacks;
• frequent urination.

After an interval of 11 to 47 hours after taking an excess dose, liver dysfunction may occur due to intoxication of the body, a complication that can cause death.

The first signs of an overdose are: nausea

First aid for overdose:

• perform gastric lavage;
• take an absorbent (activated carbon, Sorbex);
• call an ambulance.

It is prohibited to combine the medication with:

• drugs against inflammatory processes, “Aminofenazone” – increases toxicity;
• contraceptives;
• drugs to treat disorders affecting the central nervous system;
• valproic acid;
• may enhance the effect of hypoglycemic, antiviral, anticoagulants, cardiac glycosides;
• ethanol

When patients take Pentalgin simultaneously with Codeine, the effect of the drug, which depresses the central nervous system, is enhanced.

For children

A growing child's body is especially susceptible to various medications. If a child complains of headaches, this does not mean that you need to stuff him with pills.

Perhaps this phenomenon is short-term and quickly passes. The main thing is to find out the causes of pain.

Perhaps it's nervous tension or something else. Just observe the child's condition.

Source: https://MedLazaret.ru/kardio/pentalgin-i-davlenie.html

pharmachologic effect

"Pentalgin" is a combined antipyretic, analgesic, anti-inflammatory medication. It contains effective active components, the main pharmacological action of which has a positive effect on the patient’s condition. Paracetamol has a high degree of binding to plasma proteins. The drug is metabolized in the liver and excreted by the kidneys. The half-life of active substances can take from 1 to 4 hours.

The medication contains codeine, which perfectly passes through the blood-brain barrier. The substance accumulates in the body, its maximum accumulation is observed in fatty tissue, liver, lungs, and kidneys. Under the influence of tissue esterases, codeine is hydrolyzed.

Effect on blood pressure

It is better for hypertensive patients not to take Pentalgin due to the caffeine included in the medicine. Even in a healthy person, in case of long-term treatment with the drug, blood pressure may rise. Therefore, doctors do not recommend drinking it for more than 5 days.

Sometimes, under the supervision of a doctor, 7-day therapy is allowed.

Indications for use

What is Pentalgin in tablet form for? This question interests all patients. Manufacturers note that the drug has a combined pharmacological principle of action. "Pentalgin" allows you to eliminate the pain syndrome that accompanies various pathologies:

• spasm of smooth muscles of internal organs;
• muscle and joint pain;
• postoperative period;
• toothache and headache;
• feverish conditions during a cold.

Main contraindications

To understand whether Pentalgin increases or decreases blood pressure, you need to familiarize yourself with the cases in which this medication is prohibited from being used. The main contraindications of the drug include the following diseases:

• severe liver or kidney failure;
• the presence of erosive and ulcerative pathologies of the gastrointestinal tract;
• diseases of the circulatory system (severe heart disease, recent coronary artery bypass surgery, tachycardia, high blood pressure);
• hyperkalemia.

special instructions

The universal composition of the drug "Pentalgina" is designed exclusively for adult patients. This medicine should be taken with extreme caution and under the constant supervision of a doctor in old age. "Pentalgin" is not used during pregnancy and during breastfeeding. The medication is prescribed with caution for the following diseases:

• cerebrovascular accident;
• cirrhosis of the liver;
• diabetes;
• viral type hepatitis;
• seizures and epilepsy;

Pentalgin painkillers should not be taken before a blood test for uric acid and glucose levels. Otherwise, the results may be distorted. It is necessary to exercise some caution when driving a car and other technical equipment.

Use during pregnancy and lactation

It is prohibited to prescribe the medicine during pregnancy. The active substances penetrate the placenta and are concentrated in the fetal blood 50% less than in the mother. Substances contribute to disruption of normal fetal development. It is possible to terminate the pregnancy, especially in the early stages. When breastfeeding, the active ingredients pass into breast milk and are passed on to the baby. When treating the mother with this medication, breastfeeding should be abandoned and the baby should be switched to artificial formula. It is prohibited to prescribe the drug to children under 18 years of age. No clinical studies have been conducted.

It is strictly forbidden for women to take the drug during pregnancy

Can it be used for high blood pressure?

Pentalgin tablets: what do they help with, how to take them? These questions interest every patient. The pills sold today for hypertension and arterial hypertension act according to different schemes. Some of them can act as powerful inhibitors, others have a positive effect on adrenergic receptors and also block calcium channels. Diuretics deserve special attention, they are responsible for removing excess fluid and lowering blood pressure by gradually reducing the volume of blood circulation.

The composition of the medication is intended to eliminate pain. With the correct dosage of the drug, an increase in pressure is almost never observed. The effects of caffeine on the body are compensated by antispasmodics. But hypertensive patients should take this drug as carefully as possible. In rare cases, Pentalgin can provoke the development of acute headache and vomiting.

Optimal dosage

To understand how Pentalgin affects blood pressure, it should be noted that this medication has a positive effect on the body’s systems. The drug is intended exclusively for oral use. To achieve the desired result, the tablets are taken orally after meals with plenty of still water. If a patient wants to figure out whether it is possible to drink Pentalgin with high blood pressure, then it is necessary to take into account that the medication normalizes the functioning of the cardiovascular system. The drug helps eliminate the characteristic symptoms of tachycardia and hypertension. An increase in blood pressure is possible only if a person exceeds the permissible dosage.

The standard therapeutic course is based on the fact that the patient needs to take 1 tablet 3 times a day. The interval between taking pills should be at least 6 hours. To effectively combat fever, Pentalgin is used for three days. To achieve maximum analgesic effect, the drug is taken for 5-8 days. The therapeutic course can be extended only after consultation with the attending physician.

Combination with other drugs

If you combine the medicine with other drugs, you should be careful, since some effects may occur when certain elements are combined.

Depending on the substances that have been combined, various reactions may occur, for example, weakening or strengthening the properties of some ingredients.

It is not recommended to combine the drug with alcohol. In this case, an exacerbation of chronic or the appearance of acute pancreatitis is possible.

To avoid complications, be sure to notify your doctor that you are currently taking any medications. If necessary, a specialist will select a suitable analogue.

Adverse reactions

Many patients are interested in whether Pentalgin increases blood pressure. Experts always note the fact that this medication affects the patient’s body exclusively in a positive way. If you do not exceed the permissible dosage, your blood pressure will normalize. Otherwise, a person may experience various adverse reactions:

• allergic manifestations in the form of rash, skin itching, urticaria;
• cardiopalmus;
• arrhythmia;
• anemia;
• changes in blood composition;
• disorders of the kidneys and liver;
• acute pain in the stomach, nausea, vomiting, constipation, loss of appetite;
• periodic dizziness, anxiety, increased agitation, insomnia;
• decreased visual acuity and hearing.

Overdose

Painkiller tablets "Pentalgin" should be used carefully; it is forbidden to exceed the dosage specified by the manufacturer. Uncontrolled use of the drug is fraught with gastrointestinal bleeding, vomiting, pale skin, confusion, hyperthermia, and arrhythmia. Frequent urination, tremors and headache are possible. In case of severe overdose, you must urgently seek qualified help at a hospital.

To improve the patient's condition, doctors use gastric lavage followed by the use of activated charcoal. Acetylcysteine ​​can be used as a universal antidote. The administration of this drug is important during the first 8 hours after taking Paracetamol.

Constriction of blood vessels in the brain

Treatment often consists of long-term, and most often lifelong, use of medications, selected in each case, for each patient individually.

As a rule, the following drugs are prescribed:

• Lovostatin - mevacos, mefacor;
• Fibrates used: clofibrate; atromidine, atromide; simvastatin: zocor;
• Cerebrolysin, anion exchange resins, lecithin, and iodine therapy are also used;
• They also prescribe vitamins such as A, E, C, general vitamin complexes, microelements, selenium;
• Drugs that dilate blood vessels are used: aminophylline, papaverine.

Treatment is prescribed by the attending physician individually for each person and is based on the results of the examination, the patient’s condition, and his lifestyle and age.

Vasodilation

Nowadays there are more and more patients who have narrowed cerebral vessels. The reason is contributed by rare stay in the fresh air, heavy loads associated with intellectual work, overwork, and stress. As a result, people often have headaches, heaviness and discomfort. To avoid suffering, you need to dilate the blood vessels.

Often, poor circulation and narrowing of blood vessels in the brain can lead to the appearance of atherosclerosis and osteochondrosis. People often feel weak and dizzy.

Interaction with other medications

The action of the Pentalgin tablet has its own characteristics that must be taken into account. To achieve a positive therapeutic effect, you need to pay attention to the following factors of interaction with other medications:

1. Barbiturates reduce the quality of Paracetamol several times and also increase the risk of toxic effects on the liver. Diflunisal increases the concentration of the active substance of the painkiller in the blood. This situation negatively affects the functioning of the liver and the whole body.
2. Naproxen significantly reduces the diuretic properties of Furosemide.

If the patient drinks coffee and other caffeine-containing drinks during treatment, this can lead to excessive stimulation of the central nervous system. The use of Paracetamol and alcohol is fraught with the development of acute pancreatitis.

Composition of the drug and its effect

This pharmaceutical drug, according to the modern classification, belongs to NSAIDs-antispasmodics, which effectively help relieve even severe headaches or relieve inflammation, regardless of its etiology, as well as localization. At the same time, it is necessary to pay attention to the fact that this pharmaceutical drug is considered safe, since the biochemically active substances that make up Pentalgin act effectively, which is why there is no need to take pills often.

Regarding what was included in this drug:

1. Paracetamol (effectively helps to get rid of even severe headaches, and is also indicated for high fever).

1. Caffeine. It has an important clinical property to dilate blood vessels and increase the biochemical activity of brain neurotissues. This component effectively eliminates fatigue and drowsiness. It also potentiates the effectiveness of analgesics contained in the pharmaceutical preparation.
2. Pheniramine. Responsible for blocking histamine receptors.
3. Naproxen. Has an anti-inflammatory effect.
4. Drotaverine. Stops spasms.

The pharmacological form includes packages of 2, 4, 6, and 12 pieces.

According to morphological characteristics, the tablets are externally colored pale green or green. Shape - externally, the tablets look like wafers convex on both sides - capsules with uneven edges. An important point is that there must be a distinctive stripe on one side and “Pentalgin” written on the back (if this is not there, then you can be sure that this is a low-quality fake that is unsafe for health). On the cross-section, the contents of one tablet are colored green, with small whitish dots.

An important point that concerns the quantitative ratio of biochemically active substances included in the composition.

So, 1 tablet of this drug contains:

1. Paracetamol 325 mg;
2. Naproxen 100 mg;
3. Caffeine 50 mg;
4. Drotaverine hydrochloride – 40 mg;
5. Pheniramine maleate – 10 mg.

Please note that Pentalgin is available only in the given form, and a priori there cannot be any other variations.

In addition, there are also so-called adjuvants - excipients that do not have a clinically significant effect, but their presence is necessary to stabilize the prescription form (in other words, they are needed to prevent the tablet from crumbling). The main adjuvants include:

• microcrystalline cellulose;
• potato starch;
• dyescormellose sodium;
• heprolose (hydroxypropylcellulose (Klucel EF));
• citric acid monahedrate;

Available analogues

The need to replace Pentalgin with another drug arises if the patient has contraindications or is individually intolerant to the components of the main drug. In such a situation, you can purchase available analogues with an analgesic or antispasmodic effect:

1. "Pentalgin FS".
2. "Cardiomagnyl".
3. "Ibuprofen."
4. "Analgin."
5. "Efferalgan."
6. "Spazmalgon."

Analogues must be selected as responsibly as possible, taking into account all indications and contraindications for their use. Universal "Pentalgin" is one of the most powerful painkillers. But patients need to take into account the fact that the maximum positive therapeutic effect is achieved only if the medication corresponds to the specificity of the disease. Only a full examination and consultation with a doctor will help determine the real state of a person’s health. The expert will also tell you how long the Pentalgin tablet lasts.

Experts' opinion

Despite all the contraindications and adverse reactions, the use of Pentalgin allows you to achieve a positive result from the therapy prescribed by a specialist. Laboratory studies on animals have proven that this medication is absolutely safe with a single dose, which significantly exceeds the standard value. Due to this, the medication can be safely used to achieve an anti-inflammatory, analgesic, and antipyretic effect.

Patient reviews

Most often, Pentalgin is used by women during menstruation, which is accompanied by severe pain. The medication also helps to cope with aching toothache. Adverse reactions occur extremely rarely. The correct dosage and preliminary consultation with a therapist help minimize the likelihood of negative effects on the human body. “Pentalgin” with high blood pressure, as well as with very low blood pressure, should be taken as carefully as possible. It is best to combine the remedy with other medications that will help normalize the functioning of the body.

In what cases is Pentalgin prescribed?

As mentioned above, with low, and especially with high blood pressure, this drug does not help at all. But it copes well with the following problems:

• muscle and joint pain;
• headaches and migraines;
• aching pain during menstruation in women;
• toothaches;
• sharp pain from a pinched or damaged nerve.

If a person suffering from something from the above list chooses Pentalgin to alleviate the condition, he must monitor his blood pressure level before taking the medicine. You should not drink it if the tonometer gives an increased or decreased result. First you need to stabilize the pressure, otherwise Pentalgin will not have the right effect.