- causes addiction and tolerance;
reduces the metabolism of barbiturates, thereby reducing the effect of the taken dosage;
It should be remembered that these drugs are not effective against a heart attack or heart attack, therefore, in case of a severe attack of anginal pain, you must call a doctor. As a last resort, take a Nitroglycerin tablet under the tongue while waiting for emergency medical help. Also, you should not take Validol and Corvalol together to avoid an allergic reaction and side effects.
What can replace these drugs?
Validol or Corvalol have established themselves as first aid for cardiac pain as a result of their rapid effect. After taking a tablet under the tongue or taking drops, the drug quickly relieves spasm of coronary vessels and an attack of heart pain. The product is effective and
. Currently, the pharmacy offers many analogues of drugs based on valerian, motherwort, hops, mint and lemon balm. The most popular products are Persen, Tenoten, Novopassit and others.
Valocordin, validol, corvalol, Zelenin drops
Surprisingly, heart medicines originally from the early 20th century are still found on pharmacy shelves. They are not only witnesses to the popularity of pyramidon, in the past they had to coexist with cocaine and morphine. But this is not the main thing; what is much more important is that, in general, “old people” do not work, being drugs of reflex action. They also contain harmful substances and help prolong heart problems.
Behind
These drugs are time-tested. Our mothers and grandmothers drank and continue to drink them; many without “fifteen drops” of Valocordin or Corvalol (and also validol under the tongue) will not be able to calm down a restless heart, what else can they do to relieve heart pain.
Cons This is the main problem with these drugs. After all, among their components there are only soothing ones. And heart problems are associated with vascular atherosclerosis and impaired blood flow to the myocardium. “Drops and lollipops” are not able to adequately dilate the heart vessels and reduce the load on the heart (as nitrates do), and people often waste time relying on their effectiveness. As a result, a stable attack of angina becomes unstable, and a heart attack may occur.
Every time you don’t want to take serious medications, “magic drops” help not only relieve discomfort in the heart area, but also help you calm down and fall asleep.
Cons Modern doctors recognize that Corvalol and its brothers are effective only in the case of cardioneurosis and general agitation, helping to relieve both. But this is where their danger lies. The fact is that the drugs (in particular Valocordin, Corvalol) contain the sleeping pill phenobarbital, which has been banned for use in the European Union for many years. Because the drug is from the first generation of sedatives, which is called “hard”. And those who use these drugs every day (and this often happens) can harm their health.
Pros The drugs are easy to use and cheap. This is a real lifesaver for retirees. Our fellow citizens are accustomed to them, and leaving the market will be negatively perceived by society.
Cons As one doctor said, banning Valocordin is the same as introducing prohibition. Alas, society’s habit of “drops” and “lozenges” is largely due to the fact that these drugs often cause drug addiction. Due to the content of the same phenobarbital, valerian, ethyl alcohol and other components that calm the nerves, and thereby accustom us to ourselves. According to the observations of psychiatrists, stopping these medications after long-term regular use causes all the symptoms of “minor withdrawal” - irritability, aggression, a sharp deterioration in well-being, headaches and tremors.
Conclusions "Health".
We are not calling for a ban on “heart lollipops and drops.” Although some of them, containing outdated components banned in many countries, are questionable, to put it mildly. Another thing is important - they should finally begin to be used exclusively for indications. Perhaps they will have to be made prescription, or perhaps a certain monthly sales rate per patient may be introduced. The situation when many people waste time and do not receive adequate treatment for coronary heart disease is too costly for society. As is the widespread phenobarbital addiction among pensioners.
The old guard
Validol
Validol was first produced in Germany in 1897. The instructions say that this is a “Drug with a reflex vasodilator effect,” and according to the chemical structure it is menthol in the menthyl ester of isovaleric acid. There have been no clinical studies of the effectiveness of validol in coronary heart disease, and the indications for use are vague.
Valocordin This well-deserved drug consists of a whole chemical cocktail, the basis of which is bromovaleric acid, the sleeping pill phenobarbital (by the way, prohibited for use in the European Union) and ethyl alcohol. The instructions say that the medicine can help with mildly expressed spasms of the coronary vessels (I wonder who measured their severity?), but in fact it is a sedative with a slight hypnotic effect.
Corvalol
A brother of Valocordin, which inherited not only its chemical structure, but also its popularity. Unlike his older brother, he is not known outside the republics of the former USSR.
Zelenin drops
This miracle medicine contains tincture of lily of the valley, belladonna, valerian and menthol. Previously, it was positioned as a remedy for cardiac neurosis (now we will say cardialgia), and, like previous medications, it can be used under one important condition - if the ischemic nature of heart pain is excluded in advance.
conclusions
Corvalol differs from Validol in its composition, the presence of bromine and phenobarbital, and ethyl alcohol. This drug is contraindicated in women during pregnancy and lactation, with epilepsy, myasthenia gravis, acute renal or liver failure, respiratory syndrome, drug or drug addiction. In this case, preference should be given to combined herbal preparations, such as Validol or analogues, without barbiturates in the composition. To prevent adverse reactions to the drug, you should consult a physician or cardiologist before taking it.
The following sources of information were used to prepare the material.
Restrictions on taking Corvalol
It is not recommended to prescribe Corvalol for the following diseases:
- individual intolerance to phenobarbital, isovaleric acid or bromine;
- liver or kidney failure;
- decompensation of cardiac activity (edema, shortness of breath, enlarged liver, congestive processes in the lungs);
- low blood pressure;
- acute period of heart attack;
- muscle weakness, myasthenia gravis;
- drug, alcohol or drug addiction;
- lung diseases with brochospasm;
- diabetes;
- depression.
The drug is not prescribed to children under 18 years of age, during pregnancy and lactation.
Features of Validol
Validol is a drug that acts directly on the cardiovascular system.
The drug is released in tablets consisting of menthol, isovaleric acid, sugar and an excipient. Taking the drug allows you to achieve the following results:
- has a moderate vasoconstrictor effect
- normalizes blood circulation in the body
- relieves severe pain syndrome
- has a sedative effect
- helps calm the central nervous system.
However, taking validol does not always help cope with pain. In a situation where the pain is provoked by an angina attack that occurs in the heart muscle, taking the pill will not eliminate the discomfort. The pain syndrome associated with this heart disease can be relieved with a complex of validol and nitroglycerin.
This combination is due to the fact that validol tablets have a calming effect, and nitroglycerin helps normalize the size of the coronary arteries. Taking them together helps restore the functioning of the heart muscle. It is important to remember that validol is strictly contraindicated after alcohol.
Nitroglycerine
This is probably the most popular remedy that helps relieve spasms and improve blood circulation. Used for the treatment of angina pectoris and in complex therapy for the treatment of myocardial infarction. Due to the fact that the spasm goes away, the pain also goes away.
Method of administration and dosage of Nitroglycerin
Side effects and contraindications
Adverse reactions of the body | Prohibitions on taking the drug |
Nausea, abdominal pain and vomiting | Pregnancy and breastfeeding |
Reduced body temperature | Anemia |
Headache and dizziness | Arterial hypotension |
Blurred vision | Glaucoma |
Sharp decrease in blood pressure | Concomitant use with PDE inhibitors |
Feeling of dry mouth | Kidney and liver failure |
Anxiety and disorientation if there is an overdose | Thyrotoxicosis |
Features of Corvalol
The drug Corvalol is available in drops and tablets.
The drug contains active substances such as phenobarbital, ethyl bromizovalerianate, and an extract from mint leaves. Corvalol is considered a drug that has a sedative, vasoconstrictor and antispasmodic effect. It is possible to achieve a sedative effect due to the ethyl bromizovalerate present in the composition. It affects receptors in the oral cavity and thereby inhibits the functioning of cells in the subcortical parts of the brain and cortex.
Taking Corvalol helps achieve the following results:
- heart rate tone is restored
- refers to blood pressure
- has a slight choleretic effect
- dilates blood vessels localized in the heart and brain
- fights spasms in smooth muscles thanks to the essential oils present in mint.
Already 20 minutes after taking this medicine for pain, it begins to have an effect on the nerve endings. It is necessary to take the medicine as prescribed by a doctor after diagnosis. Often the medication is combined with Nitroglycerin and the indications for this combination are:
- constant insomnia
- Vascular diseases
- tachycardia
- disruptions in the functioning of the central nervous system
- neurovegetative intestinal disorder
- neuroses caused by high irritability
- high blood pressure
- vegetative-vascular dystonia.
An overdose or prolonged use of Corvalol can provoke the appearance of various rashes on the skin, an allergic reaction in the form of swelling of the nasopharynx, inhibition of the reaction and hallucinogenic visions.
Corvalol lowers or increases blood pressure: can you drink it if you have high blood pressure?
Corvalol is a traditional remedy that can be found in almost every home medicine cabinet; it is the first thing that most people use for headaches and high blood pressure, without hesitation taking on faith the experience and reviews of people of the older generation.
Meanwhile, few people can clearly explain how Corvalol works at sufficiently high blood pressure, whether it lowers it or not.
Corvalol - composition and action
The active substances contained in Corvalol primarily act on the human central nervous system.
If you have experienced stress or become very worried, and after this your pulse cannot return to normal, your eyes darken, your head is dizzy, or your heart hurts, reviews recommend taking a few drops of this remedy.
Corvalol calms frayed nerves, dilating blood vessels and thereby lowering blood pressure - which is why it is often used by patients diagnosed with hypertension. In addition, this drug does not have the following effects:
- Relieves irritability and aggressiveness.
- Helps with headaches caused by stress, as it lowers intracranial pressure and calms the nerves.
- Useful for chronic insomnia and night awakenings.
- Improves blood flow to the heart during rapid, uneven contractions of the heart muscle and thus stabilizes its functioning.
- You can drink this remedy along with antispasmodics for intestinal colic and spasms - your health will improve much faster.
Hypertension is not a direct indication for the use of these drops, but, nevertheless, they help with high blood pressure. This is explained by the high content of phenobarbitural and valeric acid derivative in the composition of the drug. These two substances reduce heart rate without inhibiting blood circulation. This is why Corvalol is so effective for severe headaches and blood pressure surges.
This medicine also contains:
- Peppermint extract – it has a sedative and antispasmodic effect, relieving insomnia and headaches, reducing nervousness and irritability;
- Ethyl ether has a very strong effect on the nervous system, helps you fall asleep quickly and soundly.
Thanks to such components, Corvalol is truly effective for anxiety, stress, emotional stress, and headaches. But hypertension cannot be cured with this medicine alone.
Corvalol for high or low blood pressure
on
If the pressure has increased due to a change in weather or climatic conditions, after strong excitement, then taking a dose of Corvalol does lower the pressure - but only the lower one and for a short time, while the blood vessels remain in a relaxed state. As soon as the effect of the active substances of the drug ends, the tonometer readings may jump again.
You can take it together with another medicine that lowers high blood pressure, it will enhance and speed up the effect. As a rule, it is recommended to combine these drops with diuretics and blood thinning drugs.
But patients diagnosed with hypertension should not use Corvalol as an independent treatment - it is not so useful in this case.
As for hypotensive people - people with low blood pressure - they can also take it as an effective sedative or cure for insomnia.
But in strict dosages, otherwise a sharp decrease in pressure can lead to fainting.
Instructions for use of the drug
When a person has a severe headache, “squeezing” in the area of the heart after an emotional shock, noise in the ears and darkness in the eyes, he looks for a remedy that quickly lowers the jumping pressure and returns good health. Therefore, often, despite what is indicated in the instructions for use, the dosage of the medicine is exceeded so that it acts faster.
The instructions for use of Corvalol do not recommend starting the drug with the maximum dosage. To return blood pressure levels to normal, it is enough to dissolve 15 to 30 drops of the product in half a glass of water and drink it in one gulp.
The effect will occur in half an hour. And only if it does not become easier, you can, if necessary, dissolve 40-45 drops in the same amount.
For people with low blood pressure, the permissible dose of the drug is no more than 15 drops. You need to take the medicine half an hour before meals or an hour after, no more than three times a day.
Difference between Validol and Corvalol
There are several ways in which these two drugs differ
- Compound. Validol is a solution of menthol in methyl alcohol and isovaleric acid. Simply put, this remedy is a mint tablet. Corvalol is a combination drug based on menthol, ethyl alcohol, phenobarbital and alpha-bromoisovaleric acid.
- Indications for use. The attached instructions for use indicate that validol is recommended to be taken for pathological conditions such as nervousness, hysterical states and a mild attack of angina. In addition, seasickness and headaches are considered indications for its use. Corvalol should be taken for mild hypertension, neuroses, spasms of the intestines and coronary vessels.
- Impact. Each of the sedatives has a specific composition, so their effect on the body has some differences. Validol has a mild sedative effect and promotes minor vasodilation. A medication such as Corvalol has an antispasmodic effect and reduces the excitation of the central nervous system. The presence of phenobarbital in it gives it a sedative and hypnotic effect.
When taking validol, addiction does not develop, while Corvalol has this property due to the phenobarbital content it contains. In addition, validol has only a weak sedative effect on the central nervous system, and an overdose of Corvalol causes a depressant effect.
General characteristics of drugs
These two drugs differ in composition and mechanism of action. The difference is that Validol is a solution of one substance, and Corvalol is a combination of several active substances.
Validol
The drug is a 25% solution of menthol in isovaleric acid ester. The mechanism of action is to irritate certain receptors inside the oral cavity. This activates the parasympathetic nervous system: the heart rate slows down and breathing becomes deep.
"Validol" dilates the coronary vessels, which helps reduce heart pain. It also indirectly affects the vestibular apparatus: nausea and vomiting during sea and air sickness are reduced. The local cooling effect of the drug has a distracting effect.
Validol enhances the effect of antihypertensive drugs and analgesics. Potentiates the effects of alcohol. May reduce attention and fine motor coordination when performing fine work and operating vehicles. Available in the form of drops (applied to a piece of regular sugar) or tablets. Both dosage forms are taken until complete absorption under the tongue. Usually well tolerated, only in some patients it can provoke the development of allergic reactions, a short-term decrease in blood pressure, dizziness and moderate headache. Validol is contraindicated in myocardial infarction. Use with caution in pregnant and breastfeeding women.
Corvalol
This is a combination of several medicinal components, which includes phenobarbital, ethyl alcohol, α-bromoisovaleric acid ester and peppermint oil. Phenobarbital reduces the activity of the centers of certain structures of the central nervous system, which provides a hypnotic, tranquilizing or sedative effect. The severity of the effect is determined by the dose of the drug used.
α-bromoisovaleric acid ester has a moderate sedative and antispasmodic effect. Under its influence, the activity of the vascular center decreases, the process of inhibition in neurons increases, and the excitability of the central nervous system decreases. Peppermint extract contains 4-5% esters and menthol and 50% menthol itself. This substance irritates local “cold” receptors on the oral mucosa. This eliminates muscle spasms in almost all internal organs and dilates the large vessels of the heart. Menthol has a moderate choleretic effect.
"Corvalol" is contraindicated in patients with severe impairment of the kidneys and liver, acute myocardial infarction, diabetes mellitus, alcohol dependence, as well as pregnant women and breastfeeding women. Can accelerate the metabolism of cardiac glycosides, indirect anticoagulants, antimicrobials, psychotropics, drugs, beta blockers, local anesthetics and analgesics.
Sold in the form of tablets and drops. It is advisable to use the liquid version not in the form of a pure solution, but on a piece of regular sugar. The medicine is not swallowed, but lingers in the mouth until completely absorbed. Among the disadvantages of taking it, a specific pungent odor should be noted.
While taking Corvalol regularly, you should avoid those activities that require precise coordination of actions and increased attention. There may be difficulties when driving vehicles.
What is better validol or corvalol
Validol is most often prescribed for mild angina, so patients with this diagnosis should always have such a drug in their medicine cabinet. In addition, the medication is prescribed for psychoses, neuroses and hysterical conditions. Validol helps to cope with insomnia, restore heart rhythm and get rid of feelings of fear. The drug is highly effective for seasickness, when the patient complains of painful headaches. Corvalol is considered an effective sedative, does not provoke allergic reactions and does not accumulate in the body.
If the patient suffers from spasms of the coronary vessels, neuroses and mild hypertension, then experts recommend taking Corvalol. At the same time, such a drug has contraindications for therapy in cases of severe pathologies of the liver and kidneys, as well as during pregnancy.
What to do if you have an angina attack
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Fatty junk food, low mobility, constant stress, chronic fatigue lead to the fact that heart disease is rapidly becoming younger. The average age of cardiology patients is approaching 40 years. And these are mostly men. They are the ones who are susceptible to angina pectoris at the most productive and working age. When faced with it for the first time, many are unable to recognize a heart attack. Therefore, they most often come to the doctor with an already advanced disease. What are the consequences of an angina attack, and how can it be stopped without serious consequences?
What is angina?
Angina itself is not a disease. This is a pain syndrome, a signal that the heart is suffering from a lack of oxygen. Insufficient nutrition of the heart muscle is the result of blockage of the heart vessels. The reasons are the deposition of cholesterol on their walls, which greatly narrows the internal diameter of the artery, or vascular spasm. The blood carrying oxygen to the heart has difficulty making its way through the narrow duct and oxygen starvation of the heart muscles occurs, as a result of which cells begin to die.
Angina pectoris
At a young age, angina pectoris occurs more often. According to the medical classification, it is classified as stable. An attack begins during physical stress (respectively, hard work of the heart) - fast walking or running, climbing a mountain, sports activities, an emotional outburst, and so on. The lumen of the vessel affected by plaques is only 50% of what it should be, and the heart has difficulty pushing blood through it. If measures are not taken, it will narrow further, and ultimately it will end in myocardial infarction.
Angina at rest
For older people, angina at rest is more typical. An attack can develop at a moment of complete rest and even sleep. This type of syndrome is referred to as unstable angina. Instability is expressed in the fact that each attack may differ from the previous one in pain and duration. The condition requires emergency medical care. Typically, unstable angina occurs after a heart attack, other serious illness, or drug treatment.
Vasospastic angina
This type is called angina of the young, and it is not associated with blockage of blood vessels by cholesterol plaques. The cause is a sudden spasm of blood vessels, causing erratic heartbeats and severe pain. If the attack is not stopped in a timely manner, it can result in extensive myocardial infarction and death. According to the classification, vasospastic angina is also classified as unstable.
Causes
They say that forewarned is forearmed. It is important to know what can cause angina and protect yourself as much as possible from this serious and life-threatening condition. The risk of its development occurs in the following cases:
- excess weight, and the more it is, the higher the danger;
- smoking, which contributes to the accumulation of cholesterol deposits inside blood vessels;
- high blood cholesterol levels;
- diabetes;
- permanent stress;
- tendency to form blood clots;
- hypertension.
For vasospastic angina, the cause may be hypothermia, as well as a hereditary factor. While excess weight and bad habits can be dealt with on your own, other causes can only be identified through a medical examination.
Signs of angina
Symptoms of an angina attack are easily confused with signs of other diseases. This is her insidiousness and is the reason that the patient does not immediately seek specialized medical help.
Stable angina
First of all, an angina attack is pain. But its character and localization are determined by the subjective sensations of the patient and can be very different. How to distinguish angina from pain associated with another disease? This can be done based on a combination of signs:
- Pain occurs in the heart area. At the same time, it can radiate to the arm, fingers and back, and can be felt like a toothache in the lower jaw. Often there is a feeling that the stomach hurts, as with gastritis or an ulcer. Less commonly, the patient feels pain in the right side of the chest.
- By nature it can be dull, pressing, in the form of burning, heaviness and even the feeling of a foreign object in the chest.
- The duration of the attack is no more than 15 minutes. May only last one minute.
- Conditions under which an attack of angina develops. Usually this is physical activity or stress.
- Conditions under which attacks are stopped. They quickly disappear at rest and after taking 1 tablet of nitroglycerin.
If all of the above symptoms are present, it means an attack of angina. The absence of all signs except pain indicates another disease not related to cardiovascular pathology.
Unstable angina
Attacks of angina at rest are more severe. They are accompanied by a jump in blood pressure. This is important to know, because the correct relief of an attack of angina depends on it. The nature and severity of the pain, as well as the duration of the attack, may be different each time. It usually occurs at rest, often at night, when blood rushes to the heart in a horizontal position. In addition to pain, it may be accompanied by difficulty breathing and a feeling of lack of air.
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One of the signs of an attack is clenched fist syndrome. The patient involuntarily squeezes his hand and holds it to his chest. Another important symptom of resting angina is a panic attack associated with the fear of death. To provide emergency assistance, the patient should always have appropriate medications on hand and know the rules of conduct during an attack.
Vasospastic angina
The onset of an attack may not be associated with physical effort. It can occur at any time, simply with a sudden change in air temperature or as a result of recent stress. Vascular spasm brings acute pain to the heart. Its localization is similar to stable angina. However, the duration of the attack is longer - from 15 to 30 minutes and the pain is more severe than with other types of syndrome. Its peculiarity is a gradual increase to a certain peak, and then a slow decline in pain. During an attack, blood pressure and heart rate may remain normal. Characteristic signs are sticky cold sweat and heart rhythm disturbances up to fibrillation. The attack may also be accompanied by low blood pressure, headache and fainting.
How to stop an attack?
Patients and their relatives should clearly know what to do during an attack of angina. A person’s life often depends on this. The simplest and most effective remedy is nitroglycerin. It is used in the form of tablets, drops or spray. One tablet of nitroglycerin is equal to three drops of liquid drug. The tablet should dissolve under the tongue in the same way as a piece of sugar with drops applied to it.
At the first signs of an angina attack, you should:
- sit down, or better yet lie down and relax:
- take nitroglycerin and chew an aspirin tablet;
- if the pain is very severe, it can be relieved with Isoket spray.
It is likely that the pain will go away within a few minutes or even seconds. Nitroglycerin quickly dilates blood vessels and ensures normal blood flow in the coronary vessels. If this does not happen, you need to take another dose of the medicine after a few minutes. You should not take more than three nitroglycerin tablets and three doses of painkillers.
Nitroglycerin is also used to relieve an attack of angina at rest. But in this case, if the attack began when the patient was in a supine position, he must be seated so that his legs are down. It is also necessary to provide him with access to fresh air to facilitate breathing. If blood pressure continues to rise, you need to give a pill that acts as an ambulance for hypertension - Clonidine, Capoten and the like. For palpitations, it is recommended to take Anaprilin. The pain, which is usually more severe than with angina pectoris, can be relieved with any analgesic - Baralgin or Sedalgin.
After 15 minutes, if the drugs used have no effect and the attack does not stop, you must call an ambulance, because myocardial infarction may develop. Cases when calling an ambulance is mandatory:
- angina attack occurs for the first time;
- pain lasts more than 15 minutes;
- pain intensifies after taking nitroglycerin;
- it is associated with nausea and vomiting, as well as shortness of breath.
Doctors are against using validol during an attack. They believe that it can blur the picture, temporarily easing the pain of an intractable attack. If it is accompanied by a panic attack, Corvalol can be taken so that the person can calm down. What needs to be done to ensure that attacks recur as rarely as possible or not happen at all? After all, when doctors talk about angina, they mean a pre-infarction condition.
Treatment of angina
For modern medicine, diagnosing all types of angina and determining its type is not difficult. The efforts of doctors are aimed at preventing myocardial infarction and relieving angina attacks. In the first case, the following measures are taken:
- lifestyle adjustments, for which the patient himself is responsible;
- drug therapy that improves the course of angina pectoris.
Medicines prescribed:
- agents that reduce the risk of blood clots;
- beta blockers, which reduce the need for oxygen in the heart muscle;
- statins, which help reduce cholesterol levels in the blood;
- drugs that prevent vasospasm.
To prevent attacks, the same beta-blockers are used. They lower blood pressure and normalize heart rate. For vasospastic angina, drugs that are calcium channel antagonists must be prescribed. They relax the smooth muscles of blood vessels and also reduce the need for oxygen in the heart muscle. Usually medications are prescribed for continuous use. You cannot stop taking them on your own. Only a doctor can do this.
The best treatment is stenting the diseased vessel. It is used in hospitals where a patient is admitted with an attack of angina. A special spring - a stent - is delivered through large arteries into a clogged or spasmodic vessel and expands in it, maintaining a constant lumen size.
Is it possible to use traditional methods to treat angina pectoris?
There are ways to combat attacks that the patient can use independently. This is a diet adjustment with the exclusion of fatty and salty foods from the diet. Regular walks - after all, angina pectoris often develops against the background of physical inactivity. Course use of medicinal herbs that have the ability to reduce cholesterol levels and improve nutrition of the heart muscle is allowed. Even a doctor can recommend herbs such as arnica or hawthorn.
It is important to know that it is impossible to completely get rid of atherosclerosis and other causes that cause attacks only with the help of folk remedies. The main thing is the treatment prescribed by the doctor. And folk recipes can only be used as an auxiliary medicine. And for vasospastic angina, it is generally not recommended to use any medications other than those prescribed by the cardiologist.
Angina pectoris, especially at a young age, carries the risk of sudden death. Its first signs are a signal of the need to urgently consult a doctor.
Can Validol and Corvalol be taken together?
The effect of simultaneous administration of validol and corvalol is determined by the dosage. The higher the dose of medications, the higher the risk of developing unwanted reactions. It is important to remember that before taking Corvalol and Validol together, you must consult a specialist.
If validol and corvalol are taken together, the sedative effect increases significantly. In some cases, this condition can lead to coma or syncope. When combined with medications from the nitroglycerin group, cardiovascular collapse may occur.
Is there a difference
The difference between these two drugs is their potency, tolerability, and suitability for use in certain patients. "Corvalol" has a more pronounced sedative effect, if taken in large doses it can be considered as a tranquilizer. When combined with other similar drugs, the sedative effect occurs faster and lasts longer.
"Corvalol" due to phenobarbital and ethyl alcohol cannot be used in patients with severe somatic pathology, pregnant or lactating women. Compatibility with other drugs is questionable, so patients who take antihypertensive and other drugs regularly should refrain from using Corvalol. It is also undesirable for people who perform work that requires composure and attention to take the drug on a regular basis.
"Validol" has a smaller spectrum of action. Its main difference is safety. A menthol solution is suitable even for a nursing and pregnant woman, an elderly person who constantly takes antihypertensive and other cardiac medications. You should not expect a pronounced effect from it; it is rather a symptomatic drug.
What is better for heart pain - Corvalol or Validol?
At the first pain symptoms in the heart area caused by a stressful condition or pathological changes in the organ, Validol or Corvalol is taken. These drugs are found in almost every medicine cabinet of older people. Which is better - Validol or Corvalol? Do medications help with one-time use or is it a placebo effect?
Painful symptoms in the area of the heart muscle are an undeniable reason to consult a doctor. Taking medications may or may not relieve pain, depending on the nature of the factor that provoked it, but will not eliminate the cause itself. In which cases it is advisable to take Validol, and in which cases Corvalol will help better, it will be easier to figure out if you know the composition of the drugs and their pharmacological action.
Angina attack: signs and pain relief at home
Symptoms in men and women
The main symptom of an angina attack is sudden pain in the chest, and people describe this condition in different ways. Some complain of a burning sensation and aching pain radiating to the left arm.
Others feel bursting pain radiating under the shoulder blade or in the stomach, neck, and throat. The attack most often lasts no more than 15 minutes and goes away on its own or after taking nitroglycerin. If this condition does not go away, it may mean that an acute myocardial infarction has occurred.
Angina pectoris most often manifests itself when:
- fast walking;
- climbing stairs;
- excitement;
- going out into the cold;
Angina can also manifest itself at rest, for example, during night sleep. This occurs as a result of spasms of the coronary vessels passing along the surface of the heart. This form of angina is called “angina at rest,” which is considered a more severe manifestation of the disease.
Similar pain sensations can also occur with neuroses, chondrosis of the upper spine, heart defects, diseases of the lungs or gastrointestinal tract, and myocardial infarction.
During attacks, nonspecific symptoms of cardiac angina may appear: nausea, vomiting, muscle weakness, excessive sweating, dizziness, panic.
Severe sudden pain in the heart area can occur in young men in the early morning or at night. Spasm of the vessels supplying the heart muscle does not always occur as a result of atherosclerosis. This type of angina is called vasospastic or Prinzmetal's angina.
Women are less likely to experience shortness of breath or pain radiating to the arm during attacks. More often they experience sensations in the form of pulsation or tingling, nausea, and pain in the abdominal area. The most common complaints in men are sharp pains in the heart that radiate to the shoulder blade or arm.
First emergency aid: what to do, what medications to take
We will tell you in detail about the algorithm of action for providing emergency first aid for angina pectoris.
If an attack occurs during physical activity, it is important to stop and, if possible, lie down or sit down. Often such rest helps relieve symptoms. At the first signs of angina, it is best to take nitroglycerin, which helps quite quickly.
If the pain symptom does not go away within two minutes, the drug must be taken again. If there is no result, you must call for medical help, as myocardial infarction is possible.
If headaches occur, you can take an analgesic. If the pulse is very elevated and reaches 110 beats per minute or more, you need to take anaprillin.
If the attack occurs at rest, the patient should be seated so that his legs are lowered. You need to loosen the collar, open the window and use nitroglycerin. Most often, medical attention is required.
You should definitely seek medical help if:
- an exacerbation occurred within two months from the onset of myocardial infarction;
- symptoms are accompanied by vomiting;
- pain does not go away after nitroglycerin for 15 minutes;
- blue discoloration of the skin appeared;
- loss of consciousness occurred;
- blood pressure has increased or decreased significantly;
- Each subsequent attack becomes more severe over the course of a month, and the effectiveness of nitroglycerin decreases.
In the normal course of the attack and long-term cardiac ischemia, if all the measures taken are effective, there is no need to call emergency services and emergency hospitalization.
Medical treatment
The main task of emergency doctors is to recognize an attack, eliminate a threat to life, identify the development of myocardial infarction, and provide medical assistance.
First of all, the doctor listens to complaints and diagnoses pain symptoms, monitors blood pressure and ECG. If the patient cannot tolerate nitroglycerin, then a Valsalva maneuver and massage of the sinocarotid area are performed. The patient is also given Corvalol 30 drops.
If there is no result, heparin is administered, oxygen therapy, neuroleptoanalgesia are carried out, and the patient is given ½ tablet of aspirin to chew.
If respiratory depression is observed, naloxone solution is administered. Seduxen is used as a sedative. If extrasystoles are detected, lidocaine is slowly injected.
What is not advisable to do when dealing with this problem?
Some people, as soon as they feel pain in the chest, immediately call emergency help. In such cases, it is better not to rush, but to try to help yourself. Providing rest is often enough to relieve an attack.
If the pain does not go away after a couple of minutes, you need to take nitroglycerin under the tongue. If there is no effect, you should take another tablet after 5 minutes. If the pain does not go away after these measures, you should call for medical help.
Some, on the contrary, neglect medical help and wait for heart pain to go away on their own, even refusing medications. This attitude is fraught with deterioration of the condition and the emergence of a threat to life.
Learn more about the disease from Malysheva’s video:
Prevention
To prevent angina pectoris, it is important to adhere to the basic rules and, first of all, the right lifestyle. To do this, you should give up alcohol and smoking. Foods high in cholesterol should be avoided in your diet. Weight control is also necessary.
The important thing is to minimize stress and anxiety. If you have had attacks before, you need to carry nitroglycerin with you and know the rules for its use. After consultation with a doctor, you can take courses of aspirin-containing medications.
"Corvalol"
The drug is available in two medicinal forms - in the form of drops and in the form of tablets. It contains the active substances phenobarbital, ethyl bromizovalerianate, as well as an extract from mint leaves. The components are the same for both drops and tablets.
Pharmacodynamics
Corvalol is a drug that has a vasodilator, sedative and antispasmodic effect. The sedative effect is achieved thanks to the ethyl bromoisovalerate included in the composition. By acting on receptors located in the oral cavity, it inhibits the work of nerve cells in the cortex and subcortical parts of the brain, thereby achieving an antispasmodic effect.
Phenobarbital, which is part of Corvalol, inhibits exciting currents in the cerebral cortex, resulting in a calming and tranquilizing result. In general, Corvalol:
- calms the central nervous system;
- regulates the tone of the heart vessels;
- reduces blood pressure;
- relieves spasms in smooth muscles due to the essential oils contained in mint;
- dilates blood vessels in the heart and brain;
- serves as a mild choleretic agent;
- enhances the peristalsis of housing and communal services due to mint oil (eliminates flatulence).
The drug begins to act 20 minutes after administration.
Pharmacological action
The drug "Validol" has:
- moderate vasodilator effect;
- has a calming effect on the central nervous system;
- sedative effect;
- improves blood circulation;
- reduces pronounced pain syndrome.
Counteracting pain with Validol does not always give the expected effect. If the pain caused by an attack of angina is localized in the heart muscle, taking medication will not relieve the pain. The complex of “Validol” and “Nitroglycerin” will help to stop it.
The advisability of taking Validol together with Nitroglycerin is that the former has a calming effect on the nervous system, and nitroglycerin normalizes the size of the coronary arteries. Together they restore the functionality of the heart muscle.
Another factor that speaks for the joint prescription of Validol and Nitroglycerin. If attacks are accompanied by dizziness, a feeling of fear and are provoked by stress, then the use of Validol alone will not give the desired result, and Nitroglycerin itself can cause a headache. Together they will cope better with the task. “Validol” will relieve headaches, and “Nitroglycerin” will dilate the blood vessels of the heart.
Instructions for use of Corvalol
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Proven by countless generations, Corvalol is the most famous sedative. In addition, it has a beneficial effect on cardiac tone and helps relieve muscle spasms. The product has a complex effect on the body and is also widely used for insomnia and neuroses of various origins. Instructions for using this drug are presented in our article.
Composition and pharmacological properties
The effect of the drug is largely due to the optimally selected composition. It is in many ways similar to another drug of similar action - valocardine. Corvalol alcohol solution contains the following important components. Composition and action of Corvalol:
- Ethyl alcohol alpha - bromoisovaleric acid has a calming and antispasmodic effect. By irritating the nerve receptors of the oral cavity, it helps to slow down the reflex excitation of parts of the central nervous system. The antispasmodic effect is aimed at smooth muscle muscles.
- Phenobarbital helps reduce excitation of the cerebral cortex. This is achieved through smooth regulation of blood pressure and relieving spasm of the vascular walls. This component has a calming and even tranquilizing effect, the intensity of which depends on the dosage of the drug. Peppermint oil in high concentrations contains esters that stimulate the prostate function of the intestines and provide a slight choleretic effect. In addition, mint oil can dilate blood vessels in the heart and brain. All this has a positive effect on the activity of smooth muscles.
Corvalol has a high absorption rate. When taken orally in the sublingual area, the effect occurs within 15 to 20 minutes. The duration of exposure is determined individually and usually ranges from 3 to 6 hours. For the fastest possible relief, you can keep the drops in your mouth, then the effect is noticeable within 5 to 10 minutes after administration.
Release form and cost of the product
Traditionally, Corvalol drops are most often in demand.
They are quickly absorbed in the digestive tract. They are sold in opaque glass bottles of 25 or 50 ml. The only drawback of this dosage form is the characteristic menthol smell, so for ease of use there is also a tablet form of the drug. Corvalol tablets are sold in blister packs of 10 pieces. The cost of the plate is from 22 rubles, and a standard bottle of drops can be purchased from 25 (for 25 ml) to 39 rubles (50 ml bottle). Compared to analogues, this is a truly inexpensive and effective sedative.
Indications for use
Corvalol is a sedative and hypnotic drug with a mild spasmodic effect. Before use, be sure to consult a doctor. Despite the fact that the product is an invariable attribute of many home first aid kits, its effects are not so harmless. In some regions, Corvalol is classified as a drug with a psychotropic effect, and its sale is carried out by prescription.
What does Corvalol help with:
- For insomnia and other sleep disorders;
- Increased nervousness;
- Relief of uncomfortable symptoms during vegetative-vascular dystonia;
- Elimination of spasm of coronary vessels;
- Complex treatment of tachycardia and other problems of the cardiovascular system;
- A sedative in various situations;
- Intestinal spasms arising from “nervous” reasons.
Corvalol is in almost every first aid kit, because it is an inexpensive and effective drug for relieving attacks of rapid heartbeat, neuroses and other uncomfortable conditions. It should be noted that regular use of this drug may have a cumulative effect, so the advisability of taking this drug should be discussed with your doctor.
Recommended dosage
Regarding the dosage and duration of taking this drug, it is best to consult with your doctor. It will help eliminate possible pathologies and adjust the drug use regimen.
Typically, patients are prescribed Corvalol 15 to 30 drops at a time three times a day. It is advisable to do this before meals, diluting the drops in a small amount of water. You can drop Corvalol onto a piece of sugar or directly under your tongue. The absorption rate of the product is quite high, which guarantees quick relief of uncomfortable symptoms.
Contraindications
Taking Corvalol is not possible if one or more of the above contraindications is detected. It is definitely worth considering that the remedy is psychosomatic, which means it cannot be used uncontrollably for a long time.
In what cases should Corvalol not be used:
- Individual intolerance to the drug:
- Serious damage to internal organs, especially the kidneys and liver;
- Severe heart failure;
- Arterial hypotension (decrease in blood pressure);
- Diabetes;
- Myocardial infarction;
- Existing drug or alcohol dependence.
Side effects after using Corvalol in the indicated quantities are extremely rare. Usually this is excessive drowsiness, headache or general weakness. From the digestive tract, nausea or constipation may occur.
Use during pregnancy and lactation
Due to the lack of information on testing this drug during pregnancy and breastfeeding, Corvalol is not used in such patients.
Can children take Corvalol?
There is no clinical data on the effect of the active components of Corvalol on the children's body. That is why it is not advisable to use this remedy for patients under 16 years of age.
Side effects and cases of overdose
Compliance with the doctor’s instructions regarding the dosage and duration of the course of taking Corvalol does not always guarantee an excellent result. Typically, when an overdose of the drug occurs, the following negative reactions of the body occur.
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What are the risks of an overdose:
- Depression of respiratory function, shortness of breath and bronchospasm;
- Heart rhythm disturbances;
- A sharp drop in blood pressure;
- General weakness, up to loss of consciousness;
- Nausea and vomiting;
- Decrease in body temperature to critical values;
- Confusion, decreased concentration.
Such conditions are especially dangerous if there are existing problems of the nervous system. Such patients require complete rest, as well as discontinuation of the drug to prevent other negative symptoms.
Compatibility with other medications and alcohol
When using Corvalol to relieve uncomfortable symptoms, you should be very careful when taking it simultaneously with the following medications.
Medicines incompatible with Corvalol:
- Sedative and hypnotic medications.;
- Analgesics and anesthetics (increases their effect on the body);
- Valproic acid preparations;
- Cardiac glycosides;
- Indirect coagulants;
- MAO inhibitors;
- Non-steroidal anti-inflammatory drugs.
It should be noted that in no case should you combine the use of Corvalol and alcohol. This combination can lead to damage to the brain, kidneys and liver due to multiple increases in drug exposure.
Storage conditions
This drug belongs to list B. This means that the bottle should be protected from light, as well as temperature changes (heating or freezing is not allowed). For convenience, you should save the original cardboard packaging, on which you should mark the date of opening of the product. Corvalol drops are stored for no more than 2.5 years after the date of manufacture. The tablet form has a longer shelf life (5 years) and also requires compliance with similar conditions.
The drug should not be used after the expiration date, and the storage location should be inaccessible to children.
special instructions
Corvalol should not be taken before engaging in work that requires increased attention and concentration. The active components of the drug have a sedative effect, so they can reduce the reaction. In addition, taking Corvalol has other features.
What you need to know:
- The course of treatment and dosage is determined by the attending physician.
- The drug can cause addiction, which reduces its therapeutic effect. In addition, regular use has a depressing effect on the nervous system and can create additional health problems.
- Uncontrolled use can also lead to bromine poisoning. This leads to the development of a specific disease - bromism.
- Corvalol drops contain a fairly high content of ethyl alcohol, which may be unacceptable when used by patients with alcohol dependence.
- In old age, the rate of absorption of the drug slows down, so the doctor may prescribe a different dosage and dosage regimen.
Corvalol does not eliminate the cause of discomfort except in cases of mild tachycardia. If you suspect problems with the cardiovascular system or central nervous system, the best option would be to go to the hospital for further examination.
In case of accidental overdose of the drug, it is necessary to urgently induce vomiting (in a hospital setting, use the method of gastric lavage). You should definitely take absorbent medications to quickly detoxify your body. If symptoms of overdose appear, it is better to immediately seek professional medical help.
Analogs
It is very difficult to find an identical composition of Corvalol, but there is a whole category of suitable pharmaceutical products with a similar therapeutic effect.
Corvalol analogues:
- Corvaltab;
- Corvitin;
- Corvitol;
- Corvitus;
- Valecard;
- Darvilol;
- Barboval;
- Valocordin;
- Reladorm.
It is very difficult to determine which drug is better and more effective. In addition to the different composition and active ingredient, this gradation does not take into account the diverse effects on the body. Only a specialist can compare well-known drugs: motherwort, valerian, hawthorn, peony and Corvalol, taking into account the individual characteristics of the patient.
Corvalol, instructions for use of which are presented in our article, is one of the most famous sedatives. It has a beneficial effect on overall well-being, normalizes blood pressure and heart rate. In addition, Corvalol is an antispasmodic, which means it helps relax smooth muscles. Features of the use and dosage of Corvalol, as well as other nuances of using the drug are discussed in the information provided.
Validol Farmak
Composition of the medicinal product: active ingredient: menthol solution in menthyl ester of isovaleric acid; 5-methyl-2-(2-propyl)cyclohexanol and -3-methyl butanoate; 1 capsule contains menthol solution in menthyl ester of isovaleric acid (validol) 100 mg; soft capsule shell composition: gelatin, glycerin, purified water, methyl para-hydroxybenzoate (E218), propyl parahydroxybenzoate (E216).
Dosage form. Capsules. Soft gelatin capsules, round in shape, light yellow in color. The contents of the capsules are a transparent, colorless or slightly yellowish, or yellowish-greenish oily liquid with a menthol odor. Cardiological drugs. ATC code C01E X. Pharmacological properties. The drug has a calming effect on the central nervous system, and also has a moderate reflex vasodilator (coronarolytic) effect through reflex irritation of sensitive nerve (“cold”) receptors of the oral mucosa.
Stimulation of receptors is accompanied by the induction of the release of endorphins, enkephalins, dynorphins and other peptides, histamine, kinins, which play an important role in reducing pain sensitivity, normalizing vascular permeability and regulating other important mechanisms of functioning of the cardiovascular and nervous systems.
Indications for use: Mild angina attacks; sea and air sickness; hysteria; neurosis; headache associated with taking nitrates. Contraindications. Hypersensitivity to the components of the drug. Severe arterial hypotension, acute myocardial infarction. Special precautions.
The drug does not contain sugar, which allows it to be used in patients with diabetes. Use during pregnancy or lactation. During pregnancy and lactation, Validol is prescribed only if the expected therapeutic effect exceeds the possible negative effect of the drug on the fetus and child.
The ability to influence the reaction rate when driving a vehicle or operating other mechanisms. When used in therapeutic doses, the drug does not affect the reaction rate when driving a vehicle or operating other mechanisms. Children. There is no experience in using the drug to treat children. Method of administration and dosage.
Adults take 1 capsule (100 mg) under the tongue. The capsule is kept under the tongue until completely dissolved. To speed up the effect, the capsule can be bitten. The dose and duration of use of the drug is determined depending on the therapeutic effect. The maximum daily dose is 600 mg. In the absence or insufficient severity of the therapeutic effect, another therapy must be prescribed within the next 5-10 minutes after administration.
Overdose. Headache, nausea, agitation, cardiac dysfunction, decreased blood pressure, depression of the central nervous system. In case of overdose, it is necessary to discontinue the drug and carry out symptomatic therapy. Side effects: With long-term use, in isolated cases, nausea, lacrimation, dizziness, abdominal discomfort, and hypersensitivity reactions may occur.
Interaction with other drugs and other types of interactions. The use of Validol in combination with neurotropic drugs that depress the central nervous system promotes falling asleep and greater depth of sleep. It is possible to potentiate the effect of antihypertensive drugs when used simultaneously with Validol.
The simultaneous use of Validol with nitrates reduces the headache that occurs when using the latter. Shelf life: 2 years. Storage conditions: Store in a dry place, protected from light at a temperature of 15? C to 25? C. Store out of the reach of children. Packaging: 10 tablets in a blister. 1 or 3 blisters included in a pack. 40 blisters each included in a pencil case. Dispensing category. Without a prescription.
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Stress and emotional disturbance
Validol quite effectively and quickly relieves excitement and anxiety due to the release of neurotransmitters and hormones of happiness. As a combination regimen, it can be used to treat mild degrees of neurosis.
Another condition for which validol can be used is hysteria and hysterical attacks. These are types of complex neuroses that are more typical for women. The condition consists of demonstrating ostentatious behavioral reactions: laughter, tears, sobs, screams, imaginary seizures and convulsions.
Often, against the background of neuroses and other nervous diseases, pain in the heart area can also occur. Validol can also help with such neurological pain. Here you need to be careful, because it is important to know exactly the true nature of heart pain.
Validol - indications
The most common dosage form of this drug is sublingual tablets that are uncoated: they are placed under the tongue and held until completely dissolved. Due to their high menthol content (60 mg), they quickly provide a local anesthetic effect, relieve nausea and dilate blood vessels. Doctors recommend Validol tablets for blood pressure, as well as for:
- seasickness;
- nausea associated with nervous tension;
- sleep disorders;
- neuroses;
- neurocirculatory dystonia.
Sublingual administration of tablets gives an effect within a few minutes (5-10 - the exact time depends on the body’s susceptibility), so Validol is well suited for the role of an emergency medication that quickly alleviates the condition, especially with toxicosis. You can take 2 tablets at a time, 4-6 tablets per day, it is advisable to maintain an interval of 4 hours between them.
Separately, you need to pay attention to Validol tablets with glucose, which have the same concentration of menthol, but are supplemented with dextrose (188 mg per 1 tablet), so they have a sweet taste. Indications for use are the same as for conventional tablets, and the introduction of glucose into the composition is explained by its ability to accelerate the action of the main component. For this reason, the effect of using Validol tablets will occur within 3 minutes.
The spectrum of what Validol helps with includes relieving anxiety and heart pain in certain diseases. Validol for heart pain is effective in the following cases:
- angina pectoris;
- pain caused by mental causes;
- heart pain caused by nervous or physical stress, fatigue;
- neurosis-like conditions;
- functional cardialgia;
In addition, Validol can help in the following cases:
- headaches caused by overexertion;
- nausea caused by motion sickness in transport;
- nausea caused by pregnancy toxicosis;
- anxiety, fear, excitement;
- Validol for coughs is effective in the form of inhalations.
In most cases, Validol is well tolerated. To prevent the drug from having a negative effect, the following contraindications should be taken into account:
- individual hypersensitivity and intolerance to the components of the drug;
- diabetes, since the tablets contain sucrose;
- childhood;
- bronchial asthma and respiratory failure, because the drug affects the respiratory centers;
- acute myocardial infarction.
Validol is used during pregnancy according to the instructions. If the pregnant woman’s body reacts normally to the drug, it is allowed to take it once if necessary. It does not have a negative effect on the fetus, so with its help a woman can reduce nausea caused by toxicosis, reduce anxiety and worries.
To understand what Validol helps with, you need to understand the effect of each of its components. The action of Validol begins with menthol. When it hits the receptors of the mucous membrane, it causes irritation. As a result, blood vessels begin to dilate, blood pressure decreases, and the heart rate decreases.
The main purpose of which Validol helps is to reduce pain in the heart. After taking this medicine, an increased amount of peptides (endorphins, enkephalins) and histamine is released into the blood. This leads to a decrease in pain and calmness. Validol has a short-term effect and does not treat serious heart disease.
Does Validol lower or increase blood pressure - the answer to this question should be known to everyone who is going to take this drug and has problems with blood pressure. An increase in blood pressure is caused by a narrowing of blood vessels and an increase in blood pressure on their walls. Therefore, to reduce blood pressure, drugs that lead to vasodilation are needed.
The range of things that Validol helps with includes panic attacks. In addition to Validol, they are prescribed: Glycised, Phenazepam and Corvalol. Some doctors also include Anaprilin in this complex for panic attacks of the hypertensive type. Validol for VSD acts as a sedative and analgesic, due to the rush of blood to the head. A few minutes after the components of Validol enter the body, the patient feels a decrease in anxiety and a decrease in headache and heart pain.
Alcohol intoxication is not included in the list of contraindications for taking Validol, however, knowledge of how Validol acts on the body leads to the idea of the danger of taking this drug while hungover. The components of Validol and ethanol have the opposite effect on the body. Ethyl alcohol leads to vasoconstriction, increased heart rate and the appearance of a nervous state. Menthol and menthyl isovalerate soothe, dilate blood vessels and restore heart rhythm.
The conflict between these two substances leads to stress on the body. The cardiovascular and respiratory systems of the body find themselves in a situation of influence of two opposing forces. This can lead to pressure surges, exacerbation of cardiovascular diseases and increased heart pain. To avoid this, you should not use Validol while drinking alcohol or in a hangover state.
Validol is well tolerated by the body and has a minimum of contraindications. Its components have a quick but gentle effect on the body. Validol, the side effects of which have not been studied only for children aged 2-10 years, has the following contraindications:
- children under 2 years of age, because menthol can lead to breathing problems in children;
- low blood pressure;
- diabetes;
- acute myocardial infarction;
- individual intolerance to the components of this medicine.
Contraindications to the use of Validol include:
- individual intolerance to components (menthol and valerian root extract);
- diabetes;
- age up to 12 years;
- breast-feeding.
Use of the drug during pregnancy requires consultation with a doctor and assessment of the risk to the child’s health. Indications for use of the drug include toxicosis in the early stages, but the vasodilating and sedative effects of Validol's components can negatively affect the blood supply to the fetus.
Side effects of Validol are most often associated with an overdose - patients experience lacrimation, drowsiness, nausea and dizziness. Before taking the drug, regardless of the situation, you should carefully read the instructions and take into account all the features of using the drug.
Validol is a remedy that has been proven over the years and quickly eliminates the unpleasant symptoms of hypertension, but its use requires a responsible attitude on the part of the patient. The drug eliminates the manifestations of the disease, but not its cause, so if there is a persistent increase in blood pressure, you should consult a doctor and undergo an examination of the body.
- Angina;
- Neurosis;
- Hysteria;
- Sea and air sickness;
- Toxicosis of pregnant women.
Validol use for hysteria. With this pathological condition, the patient’s boundary between fantasy and reality is violated, and an incredible emotional outburst occurs that engulfs the person. Being in this state, people become easily suggestible. The most common symptoms are paralysis and paresis.
Due to an emotional outburst, some patients may go blind and even stop speaking. At the same time, symptoms such as vomiting, fever, lack of appetite, tachycardia, hearing impairment, obsessive-compulsive disorders, skin rashes, inappropriate behavior may manifest themselves... All these manifestations are temporary, and the symptoms disappear after sleep or after the disappearance of the traumatic cause.
A remedy such as validol, the use of which is effective for angina pectoris, gives positive dynamics. This condition is characterized by the appearance of squeezing pain in the heart during exercise or at rest. Blood pressure rises, pulse fluctuates within different limits. The limbs turn pale and the body becomes covered in sweat.
Validol is used for sea and air sickness. The main reason for this condition is irritation of the vestibular apparatus by impulses, a changing center of gravity and uneven movements. Manifested by nausea, vomiting, dizziness, weakness, apathy, cardiac arrhythmia.
Indications for taking Validol are based on its sedative and moderate vasodilatory effect, therefore a positive result when using the drug is observed in the following cases:
- Heart pain that occurs during emotional stress.
- Neuroses.
- Hysteria.
- Violation of the vestibular apparatus during motion sickness.
- For headaches that occur after taking medications - nitrates.
- An alcohol solution is used to lubricate the skin at the site of an insect bite, it relieves pain and eliminates irritation.
Validol is almost always well tolerated; increased salivation and lacrimation may occur; this is associated with a reflex increase in secretion and is considered normal. Despite its good tolerability, the drug is prescribed during pregnancy only by a doctor; it is not given orally to children under 12 years of age. For angina pectoris, Validol is prescribed together with nitrates.
Use during pregnancy
It is especially worth mentioning the use of validol by pregnant and nursing mothers. Theoretically, the components of the drug cannot have any harmful effect on the fetus or an already born child if they enter it with mother’s milk. The catch is that extensive clinical trials have not been conducted on this category of patients. It should be noted that quite often validol helps expectant mothers well with insomnia and anxiety, and the vasodilating effect is used in the complex treatment of preeclampsia, a serious complication of late pregnancy. In this case, the drug calms the pregnant woman, lowers blood pressure and slightly improves blood flow in the placenta.
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Analogues of the drug
Validol has no analogues in structure, so in this regard it is a unique drug. If you need to select similar medications, you should rely on the pharmaceutical effect they provide. The drug Validol has the following analogues of action:
- Valerian extract - consists of natural substances and has a mild calming effect on the psyche.
- Glycine: it is based on an essential amino acid that helps reduce anxiety, improve mood and performance.
- Belloid - created on the basis of belladonna roots, effectively relieves nervous excitement.
- Deprim is a herbal medicine that helps improve mood, combat weather dependence and phobias.
- Melison is a herbal tincture with good sedative, antihypertensive and antiarrhythmic properties.
- Neurobutal is a nootropic drug that relieves mental and physiological reactions to stress.
- Persen is a natural drug that has a sedative and antispasmodic effect.
- Stressplant is a herbal medicine that helps relieve anxiety, convulsive symptoms and relax.
Validol is one of the most popular drugs, it is taken to calm down and when the “heart hurts”. It will relieve headaches during stress and after taking nitroglycerin for angina pectoris. Validol is a drug that should be in every home medicine cabinet.
How does validol work?
Validol is a solution of menthol in methyl isovalerate and is available in the form of sublingual capsules, tablets and drops. The main effect of validol is calming (sedative). At the same time, it reflexively slightly dilates the blood vessels by irritating the sensitive receptors (nerve endings) of the oral mucosa.
It stimulates the body's production of painkillers and sedatives (enkephalins, endorphins) and a number of other biologically active substances that affect the permeability of vascular walls and pain.
When validol is taken under the tongue (sublingually), its effect begins in approximately 5 minutes.
Who should take validol and to whom it is contraindicated
Validol can be taken for any pain in the heart. Of course, it will not relieve true heart pain due to angina; for this you need to take nitroglycerin. The fact is that pain in the heart during angina pectoris occurs due to compression of the arteries that bring blood to the heart muscle - the coronary arteries.
Often such pain occurs due to stress; in addition, the pain begins suddenly and can be very severe, which causes fear of death in patients. Such an attack will be relieved by simultaneous administration of nitroglycerin and validol under the tongue.
Nitroglycerin will dilate the coronary arteries, and validol will calm and relieve stress. In addition, some patients experience severe headaches after taking nitroglycerin; validol will relieve or reduce such headaches.
they can be aching, pressing, squeezing. The duration of such pain also varies - from a few seconds to several hours. Some patients complain that the beating in their heart is constant and never goes away.
Such pain cannot be relieved with nitroglycerin, since it depends on the state of the autonomic nervous system, which innervates internal organs, including the heart. But they are well relieved by taking validol - its calming, reflexive and mild analgesic effect helps perfectly with such conditions - patients calm down and their heart pain gradually goes away.
Validol will relieve signs of seasickness (motion sickness syndrome) - the cause of this condition is disorders of the vestibular apparatus caused by one reason or another. In this case, the autonomic nervous system almost always suffers.
Contraindications for taking validol are individual intolerance to this drug and very low blood pressure. Validol is prescribed with caution to patients with diabetes mellitus, as it contains sugar.
Side effects of validol include decreased blood pressure, dizziness, nausea, and lacrimation.
How to take validol correctly
Validol in the form of capsules and tablets is taken under the tongue. After taking it, it should be kept under the tongue until completely dissolved. Validol solution in drops is dripped onto a piece of sugar and kept under the tongue.
During attacks of heart pain or severe stress, you can take one to two tablets or capsules or 3 to 6 drops of validol solution under the tongue. You can take 3–4 validol tablets or capsules per day.
The daily dose of liquid validol is 9 – 24 drops. In some cases, the dose may be increased, but in this case, side effects such as nausea, vomiting and lacrimation may increase.
If validol does not help and heart pain continues to bother you within 10 minutes after taking the drug, then you need to consult a doctor so that he can prescribe comprehensive treatment.
Validol is a drug that has been successfully used for many years. Its effectiveness as a sedative, relieves emotional stress, mild analgesic and coronary agent is beyond doubt.
But if a person is bothered by pain in the heart, then, first of all, you need to understand the reason for their occurrence, that is, consult a doctor and undergo a full examination. Based on this examination, the doctor will decide whether taking validol alone is enough, or whether complex treatment is necessary.
Validol is an effective and fairly fast vasodilator drug that exhibits effective sedative (calming) and antispasmodic effects.
The medication helps eliminate severe nervousness, severe pain in the heart area, and also helps relieve nausea or prolonged vomiting.
The main active ingredient of Validol is Menthol, which has pronounced calming and dilating properties.
The onset of the therapeutic effect when the drug is absorbed in the mouth occurs within 3-5 minutes, since there is a huge number of blood vessels in the sublingual area, due to which the main medicinal effect develops quite quickly.
Main indications for use of Validol:
- angina pectoris (prolonged feeling of compression or tingling in the heart area);
- nervousness, hysteria or severe stress;
- frequent insomnia;
- nausea;
- vomit;
- cardialgia;
- moderate or quite severe headache.
Attention:
Before long-term use of Validol, it is advisable to consult a physician!
The drug is available in the form of tablets for sublingual administration (absorption under the tongue), as well as in the form of soluble drops.
- The benefits of validol are enhanced by additional substances added to the drug. Validol with glucose, among other things, enhances metabolism and stimulates redox processes in the body. This drug should be taken with extreme caution by people suffering from diabetes.
- The following drugs are also used as part of complex therapy:
- A-diston
- Advocard
- Validazol
- Dystonin
- Zelenin drops
- Cardioarginine
- Cardiolin
- Corargin
- Corvalment
- Kratal
- Lily of the valley-valerian drops
- Tonginal
- Thiodarone
- Aesculus compositum
Note! The list contains synonyms for Validol that have a similar composition, so you can choose a replacement yourself, taking into account the form and dose of the medicine prescribed by your doctor. Give preference to manufacturers from the USA, Japan, Western Europe, as well as well-known companies from Eastern Europe: KRKA, Gedeon Richter, Actavis, Egis, Lek, Hexal, Teva, Zentiva.
General information about Corvalol
Corvalol is a soothing combination medicine that contains menthol, a mixture of ethyl alcohol (96%) and phenobarbital (1.82%). The medicine also consists of sodium hydroxide, water and peppermint oil. Ethyl alcohol promotes vasodilation and has antispasmodic properties when taken at the usual dose (20 drops), and when taken at the maximum dose it provides a hypnotic effect.
Composition of Corvalol
The drug is taken orally. It is produced in the form of drops and sold in glass vials. Considering the components included in its composition and the effect it has on the body, Corvalol can be considered an analogue of the foreign medicine Valocordin.
Contraindications and side effects
Some doctors and even patients consider Validol to be “simple mints” that can be used with or without reason. Regarding tablets, this statement is relatively true, since their daily dosage can be high, but you should not overdo it with capsules. The main consequences of an overdose are:
- decreased blood pressure;
- nausea;
- vomit;
- drowsiness;
- depression of the nervous system;
- dizziness.
Some of these same symptoms (in particular, nausea and dizziness) are possible side effects from taking Validol. In addition, some people experience increased tear production. All negative phenomena go away on their own, and an overdose requires symptomatic therapy.
Characteristics of Corvalol
Corvalol has a vasodilator, antispasmodic and sedative effect. The active components of the drug act on the receptors of the oral cavity. As a result, the work of nerve cells in the cortex and subcortical regions of the brain is inhibited. Thus, an antispasmodic effect is achieved.
A drug:
- lowers blood pressure;
- calms the nervous system;
- normalizes the tone of the heart muscles;
- dilates blood vessels in the brain and heart;
- eliminates spasms of smooth muscles;
- improves the functioning of the digestive system.
The medication is produced in the form of tablets and drops.
basic information
How does it work? The drug has the following pharmacological action. When taking the medicine, the active substance has a calming effect on the body. In addition to the sedative properties, there is another effect: the drug reflexively dilates the vessels of the heart and brain, improving blood flow, slightly reducing the pressure in the vascular bed.
Validol is included in the group of sedative, vasodilating, antiemetic drugs. The medicinal component is levomenthol. Additional elements of the drug include sucrose and calcium stearate. Produced in tablets, capsules, solution. And although the additional components and dosages differ, the indications and restrictions for use are the same (Table 1).
Table 1 - Indications and restrictions for use
Indications | Restrictions |
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Taking the drug in large dosages is not recommended. When using large doses of the drug, undesirable effects occur:
- vestibular disorders;
- nausea;
- slight lacrimation;
- headache;
- lethargy;
- attacks of hypotension.
If the patient drinks the drug for a long time (large dosage), then unwanted symptoms may intensify. In this case, it is enough to stop the medicine, drink a large amount of water, take Activated Charcoal (Smecta, Enterosgel, White Charcoal) and induce vomiting. If treatment measures are ineffective, you should call an ambulance service.
What else can you replace Validol with if your heart hurts?
The drug can relieve spasm of the coronary arteries of functional origin, that is, in the absence or in the initial stage of atherosclerotic changes.
Therefore, Validol is not suitable for regular use for angina pectoris. Patients with more serious causes of pain (myocarditis, cardiomyopathy) may not get relief from this drug, or the relief is weak and short-lived. Validol will help with cardialgia, which is characterized by the following symptoms:
- occurs in the area of the apex of the heart;
- aching, stabbing or constant mild pain;
- does not change or decreases during physical activity;
- radiates to the left half of the chest;
- varied pain sensations;
- after using Nitroglycerin there is no effect.
Such drugs as Corvalment, Cormentol, Validazol, Valicardol have a similar composition. According to the mechanism of action, the pharmacy chain has the following substitutes for Validol:
- Zelenin drops,
- Corvalol drops and tablets,
- Valocordin drops,
- Corvaldin drops,
- Herbion heart drops,
- Corlex capsules,
- Cor suis ampoules,
- tinctures of valerian, mint, motherwort, peony, hawthorn,
- Kratal tablets,
- Homviocorine drops,
- Pumpan drops.
Despite the fact that most of these drugs are approved for over-the-counter sales, you need to be sure of the diagnosis before use. Therefore, if you have heart pain, it is recommended to undergo a full examination by a cardiologist. Validol cannot be used as the main treatment for cardialgia, but only for temporary relief of pain.
Validol is used to relieve heart pain, which is associated with spasm of the coronary arteries. Its action begins 5 minutes after administration. Prescribed for angina pectoris, cardiac pain with neurocirculatory dystonia, stress, neurosis, menopause. Not suitable for low blood pressure. In case of prolonged attacks of myocardial ischemia, myocarditis and myocardial dystrophy, it is ineffective.
To understand the principle of operation of this drug and in what cases it can be prescribed, you need to familiarize yourself with its composition and pharmacodynamics. The base is menthol and isovaleric acid menthyl ester. The dosage is always standard - 1 tablet contains 60 mg of menthol. Due to this composition, the main property of Validol is a vasodilator, which was taken advantage of by doctors who began prescribing it for high blood pressure. In addition, Validol has sedative activity, which is why some experts recommend it even for sleep problems.
However, not everything is so simple: Validol itself is a medicine with unproven effectiveness. In 2007, it was decided to remove it from the list of medicines that are available in pharmacies, and next to it were “arbidol”, “chondroethin sulfate”, “valocordin”, also labeled “outdated drugs with unproven effectiveness”.
The principle of operation of the active substances of Validol looks like this: when they enter the blood, they provoke irritation of receptors in the mucous membranes, which causes the synthesis and/or release of the following elements:
- endorphins;
- peptides;
- enkephalins;
- dynorphins.
They are responsible for several aspects, of which the most important are the permeability of vascular walls and the regulation of pain, as well as the synthesis of histamines. In addition, doctors emphasize that menthol is one of the most powerful antispasmodics and analgesics. However, in order to say exactly what Validol helps with, you need to clarify its release form: there are 2 of them - tablets and capsules.
Difference between drugs
When to take Corvalol and when to take Validol
The instructions indicate that Validol is indicated for the following conditions:
- cardialgia, manifested against the background of neurotic disorders;
- an attack of angina (in this case, the medicine is taken only to relieve pain);
- vegetative-vascular dystonia, characterized by disruptions in the functioning of the heart;
- state of hysteria, neurosis;
- symptomatic treatment of air and sea sickness;
- headaches during nitrate therapy.
Heart disease cannot be cured with Corvalol. The remedy can only eliminate the symptoms of nervous disorders. It is advisable to use in such cases:
- states of neurosis (irritability, anxiety, outburst of anger, depressed mood);
- functional disorders of the cardiovascular system;
- spasms of intestinal smooth muscles;
- insomnia, problems falling asleep.
Corvalol is not prescribed to patients with heart disease, because in that case it is useless.
Pharmacodynamics
The active component of the drug is obtained by dissolving menthol in isovaleric acid menthyl ester. When applied sublingually, that is, under the tongue, the active substance has an irritating effect on the receptors of the oral cavity that are sensitive to it.
Menthyl isovalerate has a stimulating effect on the central nervous system, promotes the release of peptides and the mediator histamine. These substances are necessary to reduce pain and regulate vascular permeability.
Under the influence of the active components of Validol, pain is reduced, blood circulation is improved, nervous tension goes away, and the process of natural falling asleep is facilitated. The therapeutic effect after resorption of the tablet occurs within 5 minutes.
Validol dilates blood vessels, restores heart rhythm
How to take Validol?
Validol, the use of which is described in the instructions, is recommended to be used 2 or 3 times a day, one tablet, regardless of the time of meals. The duration of treatment with the drug is determined by the doctor. If the tablets are used once to get rid of heart pain, you need to take the tablet and observe the body’s reaction. If after 10 minutes the pain has not decreased, it is recommended to use another drug.
Validol in drops is used as follows: 4-5 drops are dripped onto sugar and placed in the mouth for resorption. The effect of using the medicine occurs within 3 minutes and intensifies over the next 3 minutes. The drug in drops is used no more than three times a day, but according to indications, the amount taken can be increased.
Recommendations on how to take Validol tablets are described in the instructions. The tablet is placed under the tongue because the sensitive centers are located there. Within a few minutes, the drug begins to exert its effect, relieving pain and restoring heart rhythm. Tablets can be taken in courses or once as needed.
Validol in capsules is used in the same way as the tablet drug. The difference between capsule Validol is that it contains a larger amount of active ingredient: 100 mg compared to 60 mg in tablets. The maximum number of capsules allowed per day is 4 pieces. The maximum dose should not be higher than 600 mg. The capsules do not contain sucrose, so they are approved for use by people with diabetes.
Validol with glucose helps reduce pain, normalize heartbeat and improve mental state. This is facilitated not only by menthol and menthyl isovalerate, but also by the glucose included in the composition. It enhances the effect of active substances and accelerates metabolic processes. One Validol tablet with glucose under the tongue is enough to make a person feel better physically and mentally.
Validol is not intended for long-term use. It dulls pain, relieves acute symptoms, but is not able to cure diseases. It can be used to relieve pain caused by stress and overwork, but it should not mask serious heart problems. Validol can be used once or in courses, but the duration of the courses is determined by the doctor in each specific case.
Characteristics of Validol
Validol has a gentle effect on the cardiovascular system. The substances included in the composition give the medicine the following properties:
- moderate vasodilator;
- sedative;
- calming.
But it also copes well with pain and improves blood circulation, helping to get rid of headaches.
Validol is sometimes unable to eliminate pain. Often the pain occurs due to angina and is localized in the heart muscle. In this case, it is not advisable to take the drug, because He can't handle this kind of pain. It can be treated comprehensively using Validol together with Nitroglycerin.
Validol calms the nervous system, and Nitroglycerin restores the size of the coronary arteries. This interaction normalizes the functioning of the heart muscle.
Validol is produced in the form of drops, tablets and capsules.