According to cardiologists, Sidnopharm is an effective drug used to prevent angina attacks, as well as to alleviate symptoms during the treatment of myocardial infarction. Below we will consider the instructions for use of this medicine, its analogues and the opinions of cardiologists.
So, let's figure out what Sidnopharm helps with?
Pharmacological effects of the drug
The drug is classified as a vasodilator and a drug from the sydnonimine category. It can have the following effects:
- Expansion of the lumen of peripheral veins.
- Preventing aggregation, that is, platelets sticking together to form blood clots.
- Relieving the severity of pain during angina attacks.
The antianginal function manifests itself in the expansion of coronary vessels, due to which blood circulation and tissue nutrition are activated in the area of ischemic areas, which are blocked or narrowed channels.
This is confirmed by the instructions attached to Sidnopharm.
Indications for use of the drug
It helps improve echocardiography in patients suffering from heart failure due to narrowing or spasms of the coronary vessels. This medicine is well tolerated by patients. Thus, the drug is prescribed in the following cases:
- Prevention and treatment of attacks of angina pectoris, that is, angina pectoris.
- Chronic failure of cardiac muscle function.
- Abnormal enlargement of the right ventricle due to pulmonary disease.
- Acute failure of left ventricular function.
- Increased pressure in the vessels of the pulmonary circulation, which leads to respiratory failure.
- Treatment and prevention of myocardial infarction after stabilization of hemodynamic parameters of blood movement in the vessels. The indications of Sidnopharm must be strictly followed.
The medication significantly increases coronary reserve, which is the main property of the heart vessels, whose activity is aimed at accelerating and increasing blood volume according to the body's needs under stress conditions. Thanks to this medicine, coronary insufficiency is prevented, that is, a condition of ischemia in which the myocardium, when contracting, requires more oxygen than the blood brings. It is important to note that on the first day of administration there is a slight increase in heart rate.
Sydnopharm
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Instructions for "Sidnopharm"
As with other medications, the dosage regimen, duration of treatment and dosage of this drug should be determined by the doctor according to the patient's condition. In this case, the cardiologist pays attention to the frequency of attacks, the nature of the disease and the severity of symptoms. Eating food does not affect the function of the medicine. The tablets should be swallowed whole, without breaking, and washed down with plenty of liquid. The maximum permissible daily dose should not exceed twelve milligrams. Analogues of "Sidnopharm" should be selected by a doctor.
At the beginning of treatment, the medication is taken in a low dosage of one to two milligrams, which is half a tablet twice a day. If the therapeutic effect is weakly expressed, then the frequency of use should be increased up to three times. Next, the daily amount of the drug is allowed to gradually increase to six to eight milligrams, which are divided into three or four times. Acute forms of the disease also require an increased dosage of eight milligrams, divided into four times.
In order to prevent attacks of angina pectoris in the first few days, it is advisable to drink one or two milligrams up to six times. When an attack occurs, the tablet is placed under the tongue and dissolved.
Directions for use and dosage
Sidnopharm tablets are taken orally, without chewing, swallowed whole and washed down with a sufficient amount of water or other liquid. The effect of the drug does not depend on food intake.
The dosage regimen and duration of treatment are determined by the doctor individually. As a rule, Sidnopharm is prescribed in an initial dose of 0.5-1 tablet (1-2 mg) twice a day. If the therapeutic effect of the drug is not sufficiently pronounced, the frequency of administration is increased to three times a day. The maximum dose is 6 mg per day.
Contraindications for the use of the drug
Sidnopharm tablets should not be taken if the patient suffers from the following pathologies:
- Heart attack due to low blood pressure.
- The condition of low systolic, that is, upper blood pressure below 95 millimeters of mercury.
- Presence of glaucoma.
- Allergic reactions along with intolerance to the components of Sidnopharma.
- Pathology of left ventricular function at low pressure.
- Cardiogenic shock, which is an extremely acute condition of decreased myocardial contractions against the background of abnormally low blood pressure and the threat of death.
- Vascular collapse, that is, a lack of cardiac function against the background of a sharp drop in pressure and vascular tone, accompanied by impaired blood flow, which leads to inhibition of the normal performance of the human body.
- The presence of pulmonary edema in a toxic form, when poisons and toxins enter the organ during breathing.
- The process of cerebrovascular accident.
- Pregnancy and lactation.
- Age up to eighteen years.
- Combined use with the drug "Sildenafil".
- Patient intolerance to galactose, as well as improper absorption of glucose and galactose along with lactase deficiency.
In addition, caution should be exercised when prescribing to patients after a hemorrhagic stroke, as well as to patients who are prone to increased intracranial pressure and at the same time low blood pressure.
Contraindications
Absolute:
- Acute myocardial infarction combined with arterial hypotension;
- Hypersensitivity to the main or auxiliary components of the drug;
- Children and adolescents under 18 years of age (due to the lack of data on the effectiveness and safety of the drug);
- Collapse;
- Toxic pulmonary edema;
- Lactose intolerance, glucose-galactose malabsorption syndrome, lactase enzyme deficiency;
- Decreased central venous pressure;
- Simultaneous use of sildenafil;
- Cardiogenic shock;
- During pregnancy and breastfeeding;
- Severe arterial hypotension (with systolic blood pressure below 100 mm Hg).
Relative (Sidnopharm is used with caution):
- Elderly age;
- Tendency to arterial hypotension;
- Cerebrovascular accidents;
- Previous hemorrhagic stroke;
- Increased intracranial pressure;
- Glaucoma.
Side effects
The use of this medicine requires special attention to its dosage regimen. Adverse reactions may occur if the doses of Sidnopharm are not observed, according to cardiologists, at the beginning of treatment, thus the following side effects are likely:
- The appearance of dizziness and pain due to vasodilation, nausea, diarrhea, vomiting.
- Decreased blood pressure.
- Increased heart rate.
- Facial redness and heat due to vasodilation.
- The presence of lethargy, muscle weakness, slowness and imprecision of movements.
- Allergic reactions to the drug, expressed in the form of bronchospasms and skin rashes.
- The occurrence of anaphylactic and cardiogenic shock, which, however, occurs quite rarely.
Special conditions
Throughout the course of treatment, you must stop taking medications containing ethyl alcohol and drinking alcoholic beverages.
The drug is not used to relieve angina attacks.
When taking Sidnofarm, you should refrain from driving vehicles, dangerous and moving mechanisms, as well as activities that require increased attention, reaction speed and a high degree of cognitive abilities.
The first doses of the drug should be carried out with extreme caution and strict monitoring of blood pressure levels, due to the high likelihood of developing severe headaches, excessive drops in blood pressure and fainting.
Special instructions for the use of the drug
It should be noted that this medicine is absolutely not effective in stopping angina attacks during the acute period of development. In addition, during the first dose of Sidnopharm, you should carefully monitor your blood pressure in order to prevent it from decreasing too quickly, as well as the occurrence of severe headaches and loss of consciousness, among other things.
Due to impaired liver and kidney function, as well as a tendency to low blood pressure, older people need to adjust the dose downward, as well as to strictly adhere to it. Treatment strictly excludes the consumption of alcoholic beverages.
At the beginning of the course of therapy, it is recommended to refrain from driving vehicles, as well as from work that requires speed of reaction and concentration. This is indicated in the official annotation for Sidnopharm.
Constant supervision is necessary during the period of drug use for patients who have suffered a heart attack, hemorrhagic stroke, cerebral circulatory disorders, glaucoma and have a tendency to intracranial increased pressure, as well as those who suffer from hypotension.
You should be aware that the wheat starch included in the composition contains gluten. True, such a small amount is safe for patients with celiac disease. The dye sikovit can cause an allergic reaction among patients whose bodies are particularly sensitive to various chemical components.
special instructions
Sidnopharm is not intended for the relief of acute attacks of angina.
The first dose of the drug is prescribed with caution, monitoring blood pressure, since a strong decrease in blood pressure is possible, including loss of consciousness and intense headaches.
Elderly patients with arterial hypotension and impaired renal and liver function should adjust the dose of the drug.
During therapy, it is necessary to avoid drinking alcoholic beverages.
During the period of taking Sidnofarm (especially at the beginning of treatment), you should refrain from driving vehicles and other potentially dangerous activities that require quick reaction, increased focus, and concentration.
Analogues of "Sidnopharm"
The following medications are synonyms of the drug, that is, drugs with a similar active substance, which in this case is molsidomine:
- German tablets "Corvaton Forte", the cost of which starts from five hundred rubles.
- Warsaw medicine "Molsidomin" with a price of one hundred and forty rubles.
Analogs with a similar mechanism of action, which are included in the same pharmaceutical group with Sidnopharm, are Coronel and Cordinic. The cost of these drugs is two hundred and fifty rubles.
Reviews from cardiologists about Sidnopharm are presented below.
Reviews from cardiologists about the drug
Reviews are different. In general, cardiologists consider this drug to be a very effective remedy and prescribe it to their patients to relieve symptoms of angina pectoris, as well as to reduce the frequency of exacerbations, improve general well-being, and if there is a threat of arrhythmia due to physical stress.
True, doctors write that the effect of Sidnopharm is not strong enough for everyone. It often happens that patients require more effective medications. Cardiologists also admit that they sometimes refrain from prescribing this drug due to possible side effects. Although this is most often associated with patients’ inattention to the prescribed dosages or their unauthorized excess, as well as in cases where the contraindications specified in the instructions regarding certain pathologies are ignored.
Cardiologists emphasize that in no case should this medicine be abruptly discontinued, as this can lead to worsening heart disease. For this reason, the decision to gradually withdraw from therapy, as well as to adjust the dose or replace the drug, should be made exclusively by the doctor.
What Sidnopharm helps with is now known.
