Detralex for varicose veins: course of treatment, duration

Release forms and composition of the drug

The medication is available for purchase in the form of tablets, which are film-coated and small in size. They are packaged in blisters of 15 pieces. There may be 2 or 4 blisters in a cardboard box. They must be accompanied by instructions for use.

The dosage of each tablet is 500 mg. A larger amount of this dose, namely 90%, is represented by a substance called diosmin. The remaining 10% is represented by a component called hesperidin. Both components have pronounced therapeutic properties and complement each other well.

Additionally, the medicine contains auxiliary ingredients:

• Magnesium stearate.
• Macrogol.
• Glycerol.
• Titanium dioxide.
• Dyes.
• Sodium lauryl sulfate.

Additional components help maintain the chemical composition of the tablets and form the required shape. It is worth noting that the auxiliary ingredients do not have a therapeutic effect on the body.

Duration of use for hemorrhoids

You should not take Detralex for a long time if you have acute hemorrhoids. The patient should take 3000 mg/day for four days, dividing the dose 2–3 times, and then 1000 mg in the morning or lunch and evening (2000 mg/day). If in the middle of the course of treatment the severity of hemorrhoid symptoms has not decreased, you need to undergo a rectal examination by a proctologist. This will exclude the presence of a fistula, cancer, or other dangerous pathology of the rectum.

In the case of a chronic form, Detralex can be taken for hemorrhoids for 60 days , starting from the attenuation phase of the exacerbation. You should take a 500 mg tablet twice a day. To prevent relapse, treatment can be repeated after 3–8 weeks according to the doctor-recommended regimen.

Pharmacological properties

Detralex for varicose veins of the legs (patient reviews of this medicine are mostly positive) is used quite often, since it has angioprotective properties and normalizes metabolic processes in the walls of large vessels of the lower extremities. The main effect of treatment is observed in the veins.

Active components stimulate the restoration of the internal walls of blood vessels, reduce their permeability and help prevent stretching of the muscle layer. The last property is considered the most important, since it prevents pathological vasodilation and circulatory disorders in the lower extremities.

In addition, the medicine has venotonic properties and stimulates the restoration of damaged areas of blood vessels. Improving microcirculation in the area of ​​the affected veins can reduce the load on them and alleviate the course of the disease.

The drug Detralex in the treatment of varicose veins

In phlebology practice, Detralex is prescribed quite often and is considered the most effective and safe drug for the treatment of early-stage varicose veins. If you are prone to venous insufficiency, the doctor prescribes an annual course of medication treatment, each lasting from 4 to 12 weeks. In some cases, Detralex can be prescribed for a year. The drug has a mild effect on the body, but at the same time it steadily restores and tones the walls of blood vessels.

The duration of therapy and dosage are selected individually by a phlebologist or vascular surgeon after an in-person consultation and the necessary research.

Detralex belongs to the herbal group of drugs, since the active substance diosmin is a flavonoid from a plant of the Dubrovnik genus, growing on the Iberian Peninsula.

The product is available in the form of tablets for oral administration with a dosage of the active ingredient of 500 mg.

The action of Detralex is based on a combination of two substances:

1. Diosmin. It is a natural flavonoid and has venotonic and venoprotective effects. Strengthens the vascular wall, reduces its permeability and extensibility. In addition, it improves microcirculation and local blood circulation, stimulates lymph outflow. It was noted that the therapeutic effect of the dose taken lasts up to 82-96 hours.
2. Hesperedin. The preparation contains a small amount of it, but, like Diosmin, it is one of the active ingredients. Hesperdin helps reduce and normalize blood pressure, relaxes blood vessels and enhances coronary circulation. In addition, the substance has an antihistamine effect, so the development of an allergic reaction to the drug is minimized.

Both of the substances described above are independent drugs that can be purchased at the pharmacy. However, their competent combination in Detralex allows you to achieve good and lasting results in the treatment of varicose veins.

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Pharmacodynamics and pharmacokinetics

The pharmaceutical agent begins to act immediately after entering the patient’s body. The main active component affects leukocytes and inflammatory mediators, which helps prevent damage to the vascular wall. Thanks to this, the progression of the disease is slowed down.

Detralex in combination with hesperidin is used in the treatment of varicose veins and swelling of the legs

Diosmin also stimulates the production of cells that can restore the integrity of the walls of blood vessels when they are damaged. It additionally helps prevent the veins from stretching when large amounts of blood enter. Reducing the permeability of capillaries and large veins helps prevent swelling of the extremities. This symptom is often observed with varicose veins.

Thanks to its venotonic properties, the elasticity of blood vessels increases, which allows them to return to their previous shape after stretching. Normalization of blood circulation leads to improved tissue nutrition, reducing the risk of developing trophic ulcers on the skin of the legs.

The pharmacokinetics of the drug begins after oral administration. The tablet quickly dissolves in the digestive tract, where the absorption of the active components occurs. Diosmin and hesperidin quickly concentrate in the affected area, block inflammatory mediators, and have a therapeutic effect.

The processing of active substances is carried out in the liver. The drug accumulates in the body only in small doses and is eliminated within 24 hours after the last dose. The main amount is evacuated through the intestines, but about 14-15% is eliminated through the kidneys.

Experts have not conducted studies that could show the ability of the drug to penetrate breast milk and cross the placental barrier, but there is a version that this is possible.

In patients with pathologies of the small and large intestines, the elimination period is extended by 6-8 hours. Patients with kidney problems may also face this problem. In case of chronic renal failure, the active components can be evacuated from the body within 2 days.

Instructions

Film-coated tablets.

Compound

One film-coated tablet contains: Active substance:

Purified, micronized flavonoid fraction, in terms of dry matter, 1000.00 mg, consisting of: diosmin 900 mg (90%), flavonoids in terms of hesperidin 100 mg (10%).
Excipients:
Purified water 40.00 mg, gelatin 62.00 mg, magnesium stearate 8.00 mg, microcrystalline cellulose 124.00 mg, sodium carboxymethyl starch type A 54.00 mg, talc 12.00 mg.
Tablet core weight: 1340 mg1). Film shell:
Sodium lauryl sulfate 0.130 mg, premix for film shell of orange-pink color OY-S-8761, consisting of: glycerol 1.628 mg, hypromellose 27.039 mg, macrogol 6000 0.651 mg, magnesium stearate 1.628 mg, red iron oxide dye 0.211 mg , titanium dioxide 5.205 mg, iron dye yellow oxide 0.633 mg.
Tablet polishing aid:
Macrogol 6000 1,300 mg. The mass of the film-coated tablet is 1378.425 mg. 1) Taking into account the average moisture content of the purified, micronized flavonoid fraction - 4%, (or 40 mg per tablet), the amount of substance per tablet is 1040.00 mg.

Description

Oval tablets, film-coated, orange-pink in color, scored on both sides. The appearance of the tablet on the break: from pale yellow to yellow, with a heterogeneous structure.

• Detralex® has venotonic and angioprotective properties. The drug reduces the distensibility of veins and venous stagnation, reduces capillary permeability and increases their resistance. The results of clinical studies confirm the pharmacological activity of the drug in relation to indicators of venous hemodynamics. A statistically significant dose-dependent effect of the drug Detralex® was demonstrated for the following venous plethysmographic parameters:
• venous capacity,

venous distensibility,

• time of venous emptying.

The optimal dose-effect ratio is observed when taking 1000 mg per day. Detralex® increases venous tone: using venous occlusion plethysmography, a decrease in the time of venous emptying was shown.

In patients with signs of severe microcirculation disorders, after treatment with Detralex® there is a (statistically significant compared to placebo) increase in capillary resistance, assessed by angiostereometry.

The therapeutic effectiveness of the drug Detralex® has been proven in the treatment of chronic diseases of the veins of the lower extremities, as well as in the treatment of hemorrhoids.

Pharmacokinetics

The main excretion of the drug occurs in the feces. On average, about 14% of the administered amount of the drug is excreted in the urine. The half-life is 11 hours. The drug undergoes active metabolism, which is confirmed by the presence of phenolic acids in the urine.

Pharmacotherapeutic group

Venotonic and venoprotective agent.

ATX code: C05CA53

Treatment of manifestations of venous-lymphatic insufficiency:

• swelling of the lower extremities;
• trophic changes in the skin and subcutaneous tissue;
• venous trophic ulcers.

Symptomatic treatment of acute and chronic hemorrhoids.

Contraindications

Hypersensitivity to the active components or excipients included in the drug. The drug is not recommended for nursing women.

Pregnancy and lactation period

Pregnancy:

Experiments on animals did not reveal teratogenic effects. To date, there have been no reports of adverse effects when using the drug by pregnant women.

Lactation:

Due to the lack of data regarding the excretion of the drug in breast milk, taking the drug is not recommended for nursing women.

Effect on reproductive function:

Reproductive toxicity studies showed no effect on reproductive function in rats of either sex.

Source: https://detralex.ru/o-preparate/

Indications for use

Detralex is used not only for varicose veins of the legs, but also for other vascular pathologies. Reviews from patients confirm that timely prescription of medication helps to cope with the first manifestations of many disorders:

• Thrombophlebitis at the initial stage, accompanied by mild symptoms.

  

• Swelling of the legs at the end of the working day or during the daytime.
• Pain and heaviness in the lower extremities, manifested when wearing uncomfortable shoes.
• The appearance of spider veins of different sizes on the limbs.
• Pathological increase in the volume of the limbs for no apparent reason.

In these cases, you can use tablets that help improve the condition and prevent complications. The decision to prescribe medication is made only by the doctor. In addition to lesions of the veins of the lower extremities, the medicine is used as part of the complex treatment of hemorrhoids and venous insufficiency.

Contraindications

The medication is effective and relatively safe, but its use is not always permitted. The main contraindication is considered to be individual intolerance to any of the components in the product and a tendency to allergic manifestations.

The medicine is not used for advanced thrombophlebitis with the threat of the blood clot separating from the vessel wall and moving along the bloodstream. Another contraindication for treatment is severe renal and liver failure.

This is due to the impossibility of processing components in the body with their subsequent elimination. The drug is not prescribed for severe damage to the intestines and stomach, or a tendency to bleeding.

Detralex is not used in the postoperative period. Its administration is permitted no earlier than 2 weeks after the intervention, especially if it was performed on the organs of the digestive system.

The medication is contraindicated during pregnancy and lactation, as well as under the age of 18 years. In each case, the list of contraindications is compiled individually, taking into account concomitant deviations from other organs.

Instructions for use, dosage of the drug for varicose veins on the legs

Detralex for varicose veins of the legs (it is recommended to study reviews to familiarize yourself with the effect of the product) is used according to the standard scheme: the tablets are taken orally, washed down with plenty of water.

It is better not to chew them, since the film shell protects the active components from premature dissolution, which should begin only in the stomach.

The dosage for patients with varicose veins of the lower extremities is 1000 mg per day, that is, 1 tablet in the daytime and in the evening. It is better to use the product with food, which enhances its effectiveness and improves dissolution.

Sometimes patients with severe venous insufficiency, varicose veins and severe swelling are prescribed 2 tablets 2 times a day, but the course is usually short.

During the treatment period, it is recommended to adhere to a special regimen, that is, take food and pills at approximately the same time. It is better not to take the medicine in the morning, as it can slightly reduce blood pressure and make the patient lethargic and lethargic.

What composition?

The active components of the drug are considered harmless, as they are of plant origin. Details about these substances can be found in the following table:

It is worth noting that these substances are also available in the form of independent medications, but in combination they give excellent results in the treatment of varicose veins.

Additional elements included:

• cellulose;
• magnesium stearate;
• glycerol;
• hypromellose;
• iron oxide;
• sodium lauryl sulfate.

The medicine also contains a fraction of flavonoids, so it is considered a pharmaceutical drug with phlebotropic action.

The tablet dissolves very well in the stomach and breaks down into small particles, which allows the drug to enter the vascular wall much faster and have a therapeutic and restorative effect.

Course treatment with Detralex

In each case, the duration of use of the medication may vary. This depends on the severity of symptoms and possible complications, which are often observed with varicose veins and similar pathologies. The usual short course lasts 2 weeks, during which the patient takes 2 tablets per day.

If the disease progresses, the duration of use of the product is at least 6 weeks. Patients with chronic and advanced forms of varicose veins can be prescribed long courses of 3-5 months. The dosage of the drug should not exceed 1000 mg per day.

When prescribing a medication for long courses, a specialist usually examines the patient at least once every 2 weeks to evaluate the effect of the drug and note improvement.

Many patients say that the effect of using the tablets is not observed for 2-4 weeks. This is due to the gradual accumulation of active substances in the body. It is after 2-4 weeks that the first result appears.

Treatment course rules

For varicose veins

For the treatment of varicose veins, the required dosage is 2 tablets 2 times a day (at lunchtime and in the evening). You need to know how to take the drug correctly.

It is imperative to adhere to the prescribed course to achieve a positive effect. After seven days of use, it is necessary to reduce the dose to 1 tablet 2 times a day.

Thrombophlebitis and postthrombophlebitis syndrome

For the treatment of thrombophlebitis and postthrombophlebitis syndrome, exactly the same treatment regimen is used. It should be noted here that Detralex for thrombophlebitis is used as an auxiliary drug and for prophylactic purposes (prevention of recurrent thrombophlebitis).

This drug may also be prescribed in the preoperative and postoperative periods of phlebectomy.

Duration of treatment:

1. The course of treatment for varicose veins is prescribed for 2-3 months.
2. For thrombophlebitis and postthrombophlebitis syndrome, the course duration is up to 6 months
3. In the preoperative period, Detralex is taken for 4-6 weeks, and in the postoperative period for up to 3 months.

When taken for prophylactic purposes, the drug is taken for one month. The attending physician decides how long to take it based on the severity of the disease, the patient’s condition, and the data of laboratory and instrumental examinations.

Detralex tablets for varicose veins are distinguished by the fact that they act quickly and enter the circulatory system. Within five hours there is an active effect on swelling, reducing swelling of the legs.

Resorption of venous blood stagnation occurs thanks to micronized particles that enter the circulatory system. The substance is completely eliminated from the human body after 23 hours.

86% is excreted in feces, and the remainder in urine. When taking the drug Detralex, the course of treatment for varicose veins should be determined only by a specialist.

The medicine is prescribed to adults whose varicose veins have become chronic: there is a persistent feeling of pain, heaviness in the legs, and swelling. The tablets are taken orally.

The course of treatment may be delayed for two or more months if varicose veins are in the acute stage. Having thrombophlebitis on the list of diseases, the patient can be treated with the drug for six months.

After each meal in the morning and evening, it is recommended to take Detralex, not before meals, because it will have a bad effect on the stomach. If significant improvement is noticeable, you can stop taking Detralex once a day.

Detralex tablets can overcome the disease if it has not yet progressed. If varicose veins are neglected after surgical manipulations, they are taken during the rehabilitation period in order to protect the patient from exacerbation.

Doctors recommend drinking Detralex as a means of prevention for people who:

• lead a very sedentary lifestyle;
• deal with heavy loads;
• are in a standing position for a long time.

In this case, the drug is drunk at lunch or in the evening once a day.

During the course of treatment of varicose veins with Detralex, it is advisable to use complex therapy.

How much to take Detralex for varicose veins?

The course of treatment with the drug is determined by the doctor. As the course progresses, he examines the patient’s condition, prescribes tests and examinations, and determines the effect of treatment, thus establishing the duration of the medication.

It must be remembered that pills alone are not able to cope with the disease, no matter how effective they are. Usually, in addition to Detralex, other medications are prescribed in combination with the treatment of varicose veins; wearing compression garments and moderate physical activity are also recommended.

How long can you take Detralex for varicose veins?

The minimum course of treatment with this drug is two months. But most often you have to drink it for much longer, and sometimes take it for a whole year.

After the main course of treatment has been completed, these tablets are recommended to be used for preventive measures.

How to take Detralex for varicose veins?

Inside, during meals, 1-2 tablets at a time, washed down with water. Per day - no more than 4 tablets for the treatment of varicose veins. For the treatment of acute hemorrhoids, the drug is used according to a different scheme.

Interruptions in the course of treatment are unacceptable: breaks (forgot to take a pill) or exceeding the evening dose (if you forgot to take the morning dose) can negatively affect your health.

The easiest way is to associate taking the medication with lunch or dinner time; you can also set an audio reminder on your phone.

For acute hemorrhoids, it is prescribed to take Detralex three tablets twice a day, with meals. When used according to this scheme, a loading dose of the drug will have an effect on inflamed hemorrhagic nodes and reduce pain.

For chronic hemorrhoids, you should take the medicine 2 tablets 2 times a day along with meals.

— the main composition of these tablets is of plant origin;

— the effect of using this medicine occurs after almost a month of treatment;

- after taking Detralex, your legs hurt and tingle less;

— the drug helps get rid of vascular networks and hemorrhages under the skin;

- the course of treatment with Detralex tablets is quite long - several months, but the effect is worth it;

— the drug is not cheap, but effective;

— it’s good that this remedy is allowed to be taken in the third trimester of pregnancy, when the appearance of varicose veins and hemorrhoids is most likely.

— it has been clinically proven that Detralex has a positive effect on blood vessels: both venous and lymphatic;

In addition to drug treatment, you can try using folk remedies. So, a shower gives a good effect.

Gradually, over several days, you need to massage your feet with a stream of water from the shower. Every day, by lowering the water temperature a little, you will gradually switch to cold water - and this will give the most significant result.

If it is difficult to pour cold water on yourself, give yourself a contrast shower: turn on hot and then cold water for a few seconds, and you must finish the procedure with cold water. After such a shower, your feet should turn red.

Rub them with a towel and lubricate them with nourishing cream.

Foot baths help a lot. Please note that if you have varicose veins, you should not take hot baths.

To prevent your feet from getting tired during the day, take a bath in the morning according to this recipe. Birch, nettle and burdock leaves (take 1 tablespoon of each) are brewed with 1 liter of boiling water and left for half an hour. Next, the resulting decoction must be diluted with warm water (so as to bring it to body temperature), and you can take a bath. You need to keep your feet in the broth for at least 20 minutes.

A bath of lemon balm, oregano, chamomile and nettle tones the blood vessels in the legs. Take 2 cups of the mixture (mix all herbs in equal parts) and brew with a liter of boiling water. After the broth has infused, add 2 liters of water and keep your feet in a warm bath for 20 minutes.

Please note that folk remedies cannot completely rid you of varicose veins, but will only stop its development.

Side effects

Detralex for varicose veins of the legs (reviews about the product are mostly positive) is used most often, since it rarely provokes negative reactions from internal organs.

But complications can develop if instructions are not followed:

• Headache and dizziness.
• Weakness and sleep disturbance. In this case, the patient does not notice the changes immediately; he considers them a consequence of overwork or nervous tension.

  

• Nausea and vomiting not associated with food intake. The patient's condition usually improves after gastric emptying.
• Stable reduction in blood pressure.
• A disorder of the intestines, manifested in the form of loose stools or persistent constipation.

Such manifestations are considered rare. Usually the medication is well tolerated. In patients with a tendency to allergies, a rash may appear on different parts of the body, arms and legs. In this case, severe itching and swelling of the skin is not observed, but the rash still provokes discomfort.

Side effects

Adverse reactions during treatment with Detralex 1000 are mild in severity.

There were complaints of general malaise, headaches/dizziness;

Patients often reported the development of diarrhea, nausea/vomiting and dyspepsia;

Less often they complained of pain in the abdominal area;

Rare cases of the development of angioedema have been described;

Occasionally, rashes accompanied by itching, urticaria, and isolated swelling in the area of ​​the lips/eyelids/face were recorded.

Additional instructions

The use of this drug when the patient's hemorrhoids worsen does not involve the cancellation of other courses of treatment in the anal area. If there is no therapeutic effect in eliminating symptoms, you should see a doctor to prescribe another treatment option.

If you have venous circulatory disorders, you should lead a healthy lifestyle, combined with courses of medical therapy. Experts recommend that the patient walk, normalize his body weight, and avoid prolonged exposure to the open sun. Staying on your feet for a long time brings a lot of harm. It would be a good idea to wear stockings with a special effect that will improve blood circulation.

Patients undergoing treatment with Detralex can drive.

Overdose

Overdose of the drug is extremely rare, since the active component accumulates in the body in small quantities and is eliminated quite quickly, provided there are no pathologies of the digestive tract and kidneys.

But if a large dose of the drug is used, an increase in the manifestations of the allergic reaction is observed. The rash spreads to large areas of the skin, small pimples increase in size and fill with clear or cloudy liquid. The patient notices increased itching; he scratches the affected areas, which leads to the formation of a weeping surface.

It is at this stage that the likelihood of infection and the development of inflammation of the skin increases. In addition to external manifestations, general disorders are observed in the form of weakness, increased or decreased blood pressure. Somewhat later, lacrimation begins, symptoms of allergic rhinitis appear and a large amount of clear mucus is released from the nose.

In exceptional cases, it is possible to develop Quincke's edema, in which swelling of the mucous membrane of the upper palate and larynx is observed, which leads to breathing problems or even suffocation. In this case, the patient needs immediate medical attention, since the condition threatens not only health, but also life.

Development of adverse reactions

According to reviews, Detralex is well tolerated and does not cause serious side effects. However, in some cases, often with incorrect dosage, some disturbances from the gastrointestinal tract are possible:

• feeling of nausea, vomiting, abdominal pain;
• increased gas formation, bloating;
• discomfort after eating, heartburn.

In very rare cases, other adverse reactions may occur. As a rule, they are observed when using excessively high doses of the drug. A possible result of non-compliance with the dosage may be a significant decrease in blood pressure, accompanied by weakness, dizziness and the risk of loss of consciousness.

On the part of the skin, an allergic reaction may develop: redness, hives, rashes, itching.

Patients often note the development of pain at the beginning of therapy, but it quickly decreases, which does not require discontinuation of the drug.

During treatment, it is recommended to monitor your health and note any changes while taking Detralex.

special instructions

The use of the drug for severe varicose veins with the development of complications cannot replace more radical methods of therapy. During the treatment period, experts recommend completely abstaining from drinking alcohol, since the breakdown products of ethyl alcohol have a negative effect on the body, especially on the blood vessels and heart.

Doctors also insist on adjusting the diet and daily routine for patients who are obese or overweight. It is recommended to walk and exclude flour, confectionery, and fatty meats from the menu.

During treatment, patients with chronic venous insufficiency are recommended to wear compression stockings, which reduce the load on the affected vessels. This will allow you to obtain a more pronounced therapeutic result.

Drug interactions

The interaction of the drug with other medications has not been studied, but experts do not recommend using it simultaneously with potent antibiotics and hormonal medications.

The drug should not be combined with other venotonic medications for oral administration. However, simultaneous use of Detralex with venotonics for external application brings a good effect. Gels and ointments can only enhance the effect of the product.

Tablets are often used as part of complex treatment with vascular drugs, for example, Pentoxifylline and its analogues. It is worth noting that when using the medicine with other groups of drugs, no negative reactions are observed, but doctors do not recommend combining medications on your own.

Detralex analogues and interactions with other drugs

The drug Detralex can be replaced with the following analogues:

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1. Venarus. It is a complete analogue of Detralex; it contains diosmin and hesperidin, so the principles of treatment are the same as those of Detralex.
2. Venozol. Its components are similar to Venarus and Detralex.
3. Phlebodia 600. The drug has a similar therapeutic effect and effect, but there is more of such a substance as diosmin than in Detralex.

A similar mechanism of action is observed in such drugs as:

1. Ascorutin.
2. Venolek.
3. Antistax.
4. Vasocket.
5. Venoruton.
6. Troxevasin.
7. Rutin.
8. Troxerutin.

The cheapest analogues in this regard are Ascorutin and Rutin.

Detralex is most often compared with a drug such as Phlebodia 600, in which the concentration of diosmin is 150 mg per tablet higher, but Detralex helps better due to the presence of hesperidin in a volume of 50 mg per tablet.

In addition, during its production, a unique processing technology is used in relation to the active substance, so the absorption of the drug occurs much faster and more fully. Direct studies regarding the interaction have not been conducted, but according to extensive post-registration experience, the drug can reduce erythrocyte aggregation and blood viscosity.

Based on this, you need to be very careful when taking Diosmin and Aspirin or other blood thinning drugs at the same time. A combined course of Metronidazole and Diosmin changes the plasma concentration of Metronidazole, as well as its metabolites (metabolic intermediates) contained in the urine

Additional recommendations may include wearing compression garments and elastic bandages to provide additional support to the arteries and veins. In addition, it is recommended to develop a special treatment menu, which will consist mainly of vegetables and fish. Walking for at least half an hour will be extremely beneficial for the body.

Advanced cases of the disease require the intervention of antibiotics, anticoagulants or thrombolytics. Only a qualified specialist will tell you how much and how to wear underwear, what products to choose for your daily diet, as well as what additional medications you need to take.

Analogs

Detralex for varicose veins of the legs (reviews of the product should be studied before starting a therapeutic course) is considered the most preferable treatment option, but in some cases it cannot be used. There are several substitutes that have a similar or different composition, but have a similar therapeutic effect.

Troxevasin strengthens blood vessels and capillaries, prevents varicose veins.
Analogs of the drug are used only after consultation with a specialist. Self-administration of medications is strictly contraindicated.

How to take Detralex correctly for varicose veins of the legs

Varicose veins on the legs are a common disease among modern people, and it is not as harmless as it might seem at first glance.

Proper therapy should be comprehensive and include various techniques; Detralex is often used as a conservative treatment with drugs.

Only a doctor should prescribe it, since only he can tell you how to take Detralex for varicose veins in your case in order to achieve the desired result and not harm the body.

Features and composition of the drug

Many medications are used to treat varicose veins, but doctors usually start therapy with Detralex. The course of the disease can be divided into several stages, starting from the appearance of spider veins and ending with the formation of ulcers and blood clots in the absence of treatment.

However, it should be remembered that the effect of this drug is aimed specifically at treating pathologically dilated veins, and all complications that arise will have to be treated separately. For this reason, in order to reduce your medication costs and make therapy faster, you need to consult a doctor when the first symptoms of the disease appear.

Almost 90% of the product is diosmin, which helps to narrow dilated blood vessels, increases venous tone and prevents blood stagnation.

The rest of the medicine is hesperidin, another component that has a tonic effect on the veins and improves blood circulation. The following are used as additional substances:

• microcrystalline cellulose, used as a structuring agent, thickener, emulsifier and stabilizer;
• magnesium stearate, which acts as a stabilizer;
• sodium carboxymethyl starch, used for stabilization, emulsification and bonding;
• gelatin, which forms the tablet form;
• purified water as solvent.

Thanks to the action of the active components, Detralex relieves inflammation and acts as an antioxidant, that is, it protects the body from the action of harmful substances formed during the oxidation of food. The drug also tones the veins and helps protect blood vessels from adverse effects.

The medicine is excreted from the body naturally, without forming deposits, with feces and urine. As a rule, the half-life lasts 11 hours, during which time active metabolism occurs, as a result of which the active components are absorbed into the blood, which are then distributed throughout the body.

Feedback on effectiveness

Detralex is considered a fairly effective medication for varicose veins of the legs, so it is often used. Patient reviews are mostly positive. Many patients say that the effect appears within a few days after starting the course.

But some patients say the medication is not effective and its cost is not justified. Despite this, the drug is actively used in the treatment of people of different genders and ages.

Article design: Vladimir the Great