How to take Detralex for hemorrhoids: instructions for use

Release forms, composition

Detralex hemorrhoid tablets are produced in France, in blisters of 10 pieces, packaged in cardboard packs with a first-opening control system. This is the only pharmacological form of the drug. The drug is not available in suppositories or liniments. Detralex tablets belong to the group of venotonics (phlebotonics), eliminating the main cause of hemorrhoidal disease - weakness of the veins. The drug is extremely effective for the treatment of hemorrhoids of different locations.

The effectiveness of Detralex is related to its composition. The preparation contains five bioflavonoid components. These are natural plant polyphenols:

• Diosmin solves the main problem - balancing venous tone, including in patients who have a hereditary predisposition to venous weakness. Due to the angioprotective properties of the substance, vascular permeability decreases and microcirculation of varicose cavities improves. Diosmin affects the absorption of norepinephrine, a hormone that has a vasoconstrictor effect, which actively prevents varicose veins. In the States it is sold as a dietary supplement.
• Hesperidin from lemon or red pepper peel potentiates diosmin, enhances its qualities, protects veins from inflammatory exudate, and reduces tissue pastosity.
• Diosmetin is a bioflavonoid, a diosmin aglycone (devoid of carbohydrates in its structure), which has antitumor activity and can block the proliferation of epithelial cells and the growth of hemorrhoids.
• Linarine is an alkaloid from toadflax, which stimulates bile synthesis, improves intestinal motility, and facilitates bowel movements.
• Isoroifolin – improves the reparative abilities of tissues of the anorectal area.

The maximum concentration in Detralex is reached by diosmin and hesperidin, which provide the main therapeutic effect of the drug. This is the only phlebotropic drug that contains purified plant bioflavonoids in microform. The maximum reduction in particle size of the active fraction guarantees rapid absorption after oral administration, that is, an almost instantaneous therapeutic effect with an efficiency of 100%.

Properties of Detralex

Treatment of hemorrhoids with Detralex is aimed at relieving negative symptoms and preventing chronicity of the pathological process. There are no gender differences in its use; the drug is equally effective for the treatment of hemorrhoidal disease in men and women. The essence is the normalization of blood flow in the anorectal area against the background of a general balancing of venous circulation in the body.

The properties of a venotonic and angioprotector allow the drug to reduce the distensibility of veins, normalize venostasis, improve lymphatic drainage, and increase the resistance of blood vessels to negative influences. Detralex blocks the adhesion of leukocytes to the vascular endothelium, which reduces the deforming effect of inflammatory mediators on venous valves.

The advantages of Detralex among analogues in terms of composition and mechanism of action include:

• multi-vector, multi-directional therapeutic effects, since flavonoids enhance each other (the effect of the transition of quantity into quality), prolong the duration of the therapeutic effect;
• the speed of achieving the planned result due to the nanostructure of the active substances (it is no coincidence that Detralex is used in the postoperative period, where maximum speed of pain relief, prevention of inflammation, and pastosity are necessary);
• complex effect on vein tone, vascular permeability, regeneration and recovery processes, blocking the progression of hemorrhoids at different stages of development, preventing the formation of new nodes.

Mechanism of action

The drug is quickly absorbed in the digestive tract and enters the general bloodstream. The complex effect manifests itself much faster than when using similar products.

What effect does:

• Relieves inflammation.
• Has a slight anesthetic effect.
• Strengthens the walls of blood vessels.
• Helps relieve swelling.
• Improves blood circulation.

The effect of using the drug is noticeable already at the beginning of treatment, but final recovery will occur only after a radical change in lifestyle, eating habits and a comprehensive solution to the problem.

Indications

According to the instructions for the drug, the use of Detralex for hemorrhoids increases hemodynamic parameters with impaired venous outflow. Therefore, its main purpose in complex treatment is:

• chronic venous insufficiency, including genetic ones;
• hemorrhoidal disease of any location, form, stage, severity;
• the appearance of the first symptoms of hemorrhoids due to physical inactivity and a sedentary lifestyle;
• itching, irritation, dermatitis, eczema of the anus;
• blood in the stool;
• periodic prolapse of hemorrhoids, which are reduced into place independently or by the patient’s hands (unreducible, advanced version of hemorrhoids requires the use of tablets during preparation for and after surgery)

Factors that provoke hemorrhoidal disease include:

• pregnancy;
• constipation;
• strength sports;
• alcoholism, smoking, drugs;
• overeating, predominance of salty, smoked, canned foods in the daily diet;
• inflammation of the pelvic organs.

If at least one of them is accompanied by hemorrhoidal symptoms, a consultation with a proctologist is necessary. The sooner Detralex is used for treatment, the greater the chances of complete relief of the disease without surgical intervention.

Side effects

According to the instructions, Detralex is well tolerated in the treatment of hemorrhoids. Negative symptoms are rarely possible, which do not require discontinuation of the drug, but only dose adjustment.

From the gastrointestinal tract:

• dyspepsia;
• diarrhea;
• constant nausea;
• vomit;
• epigastric pain;
• inflammation of the large intestine.

From the nervous system:

• migraine;
• dizziness;
• weakness, weakness;
• sometimes prodrome phenomena.

From the skin, mucous membranes:

• rashes;
• hives;
• allergic dermatitis;
• tissue pastiness;
• angioedema.

Such manifestations do not carry any serious consequences, only a feeling of discomfort. But contacting a doctor is necessary, since a dose adjustment or drug replacement is necessary so that the quality of life is not impaired.

Negative consequences

Taking the drug in some patients may be accompanied by undesirable reactions of the body:

• headache;
• weakness;
• dizziness;
• nausea;
• diarrhea;
• signs of allergies.

Almost no negative consequences have been identified. If alarming symptoms appear, you should stop taking the drug and consult a specialist to change the course of treatment.

The medicine does not suppress the functioning of the nervous system. You may drive a vehicle during treatment.

While taking Detralex, some individuals may experience unwanted side effects.

Detralex for hemorrhoids: dosage regimen

According to the instructions, the optimal effect of taking Detralex for chronic hemorrhoids is 2 tablets/day at a time. It has been experimentally proven that the drug is almost completely metabolized, excreted through the intestines (up to 80%) and in the urine (15%). The course of therapy with Detralex, the dosage is calculated by the doctor individually, taking into account the form, stage, severity of hemorrhoids, the general condition of the patient, and his age. On average, this is a week, but can last up to three months. There is an option when taking the drug is divided into two doses: morning and evening.

For acute hemorrhoids, Detralex is prescribed immediately in a loading dose: 6 tablets, divided into two doses. This is a treatment regimen for hemorrhoids of any location for the first 4 days. Over the next three days, the dose of the medicine is reduced to four tablets in two doses. Drink the drug during meals so as not to irritate the gastric mucosa. The first result is obvious within 12 hours after the first intake of the tablets. Treatment is carried out in a short course under the supervision of a doctor.

In case of exacerbation of hemorrhoids, treatment with Detralex does not replace specific therapy for other diseases of the anorectal area.

Reviews

Alexey, 28 years old

When the doctor discovered that I had chronic hemorrhoids, I didn’t believe it at first, because I had never had any special problems with my stool. Therefore, at first I refused to undergo treatment, I did not see the need for it, because nothing hurt. Where did he get this from? Only a couple of months later the pain came with triple strength, hemorrhoids the size of beans appeared, and even blood appeared when going to the toilet. Only then did I begin to sound the alarm and began treatment. I bought the much-vaunted drug Detralex and took it for a week before the first improvements appeared.

The bleeding disappeared after a couple of days, and with it the pain. The remaining symptoms disappeared gradually as they approached the end of the course. The full course took me about two months, but I definitely need to take breaks.

Tatyana, 49 years old

I remember when I had internal hemorrhoids, I immediately went to the doctor. It was terribly uncomfortable and embarrassing, but the pain and bleeding from “one place” made me overcome the shame. The doctor immediately discovered the cause and form of the disease and said that it was all due to excess weight and a sedentary lifestyle. He prescribed me Detralex tablets. I saw them in advertisements more than once, so I immediately agreed to take the branded medicine.

I can say that the tablets are very good, it’s not for nothing that they are praised and advertised. The first symptom that went away was bleeding. Gradually the stinging and pain calmed down, irritation and burning went away. But you need to take the full course in order not only to relieve the symptoms, but also to restore the intestinal walls.

Olga, 34 years old

I have never had such problems, even with the chair everything was always fine. I only developed hemorrhoids when I was 6 months pregnant. The illness was very difficult to bear during pregnancy and did not leave until the birth of the child. Then the treatment became more effective, because I fed the baby not with breastfeeding, but with a special formula. It was possible to take potent drugs. I immediately bought Detralex tablets, took two courses in a row, and combined them with heparin ointment.

When the pain and unpleasant sensation of the anus bulging passed, I simply beamed with joy. Finally, the drug brought long-awaited relief. Only the doctor told me that to prevent the pills, I need to take another course periodically.

Detralex during pregnancy, breastfeeding

The naturalness of the product makes it possible to prescribe Detralex to pregnant women if necessary. Moreover, numerous clinical experiments have not revealed the teratogenicity of the drug. However, by default, any drug during pregnancy is considered contraindicated, since there is no guarantee of its inertness towards the fetus. Therefore, doctors recommend the use of Detralex for hemorrhoids in pregnant women, starting from the third trimester.

Due to the lack of data on the excretion of the drug in milk, breastfeeding during the use of Detralex is not recommended.

Contraindications for use

Tablets for developed hemorrhoids Detralex have a minimal number of contraindications. According to the medical instructions, you should refrain from using the drug if you are hypersensitive to the active and minor ingredients.

In addition, the tablets are not recommended for use by nursing mothers, not because of the toxicity of the components, but because of the lack of information regarding whether the components of the drug pass into breast milk.

Drug interactions

No symptoms of Detralex overdose were recorded during the entire clinical observation period. But the potential possibility of such intoxication cannot be excluded. In this case, it is necessary to rinse the stomach, take an adsorbent (activated carbon, Filtrum), and consult a proctologist.

Detralex for hemorrhoids is inert in relation to other drugs, which makes it the drug of choice in the complex treatment of hemorrhoidal disease. Despite this, venotonic tablets have their own characteristics that should be taken into account when treating the disease:

• the maximum effect from using Detralex is possible only when combined with external medications;
• the duration of treatment (especially at home) must correspond to the time limits specified in the instructions for one or another form of the disease: the lack of results after this period is not a reason for extending the time period, but the need to consult a doctor;
• tablets of the drug should be combined with diet therapy, an active lifestyle, and constant monitoring of bowel movements.

Analogs

In the Russian Federation there is a complete synthetic analogue of Detralex - this is Venarus. Venotonic based on the flavonoids diosmin and hesperidin, has angioprotective properties, costs 490 rubles. This is a generic drug that began to be produced in Russia after the patent of the French company expired. The product has passed all the necessary clinical trials and has an identical active component to the one patented by the company - the original developer of the drug.

In addition, many drugs are analogues of Detralex in composition and mechanism of action:

• Venozol - capsules contain the same bioflavonoids as Detralex, but are supplemented with other plant extracts, so in fact they are not considered drugs, but dietary supplements. However, they have a significant tonic effect on the veins of the anus and rectum, stimulate bowel movements, relieve inflammation, and pain from hemorrhoids (50 rubles).
• Dioflan is an effective remedy for oral use, which has a venotonic and angioprotective effect in hemorrhoidal pathology (540 rubles).
• Daflon is an angioprotector, phlebotonic for the symptomatic treatment of hemorrhoids and chronic venous diseases. Relieves pain, heaviness in the legs, cramps, swelling. The drug is one of the few effective for acute hemorrhoidal attacks, which makes it the drug of choice in case of emergency care.
• Venolek is a drug based on diosmin, used to treat varicose veins in various areas of the body, including the anorectal zone, relieves pain, inflammation, and increases the tone of the veins (470 rubles).
• Phlebodia 600 - capsules with a vascular tonic effect, are responsible for microcirculation of the anorectal area, restore the valves of the veins of the lower extremities (800 rubles).
• Vasoket is a venotonic based on the flavonoid diosmin with angioprotective, vascular wall restoration, and anti-inflammatory properties. Reduces the size of hemorrhoidal cones (600 rubles).
• Antistax is a phlebotonic drug based on grape leaf extract, used for the simultaneous treatment of hemorrhoidal disease, varicose veins, and venous insufficiency (580 rubles).
• Pilex - the medicine is based on purified mumijo, other, exclusively natural components that give the drug special properties: venotonic with anti-inflammatory, anti-edematous, analgesic effect during the formation of hemorrhoidal cones. Stimulates defecation. Indicated for the prevention of hemorrhoids of any form (600 rubles).
• Chemoroidin - capsules based on inulin from chicory, gingko biloba, prevent thrombosis, relieve inflammation, exhibit phlebotonic properties. Feature: complete absence of side effects. Indicated for hemorrhoids of any location (600 rubles).
• Troxevasin is a drug based on rutin. A good antioxidant that reduces inflammation and rejuvenates blood vessels. Increases the tone of the veins, improves microcirculation of the rectum and anus, relieves swelling, inflammation, pain (300 rubles).
• Troxerutin is another venotonic based on rutin: an angioprotector with P-vitamin activity for hemorrhoidal disease (330 rubles).
• Ascorutin is a combination of the flavonoid rutin and ascorbic acid. Restores vitamin C and P deficiency and exhibits angioprotective properties. A derivative of the drug - Ascorutin D - for diabetics (contains sorbitol instead of sugar). The product is used to treat hemorrhoids at any stage (40 rubles).
• Venoruton is a synthetic derivative of rutin based on hydroxyethylrutoside. It has a phlebotonic, angioprotective effect on the veins and capillaries of the rectum, relieves cramps, swelling, pain, and participates in the complex treatment of hemorrhoids (300 rubles).
• Venoprotect – Doppelhertz active. The combined venoprotector has antispasmodic properties, normalizes microcirculation in the anorectal area, and restores vascular elasticity (350 rubles).
• Normaven is a rutin-based dietary supplement that normalizes venous outflow, increases the tone of the veins of the rectum and anus, affecting the condition of vascular valves (385 rubles).
• Cyclo 3 forte capsules are an angioprotector based on hesperidin, reduces capillary permeability, affects lymphatic vessels, improves microcirculation of hemorrhoidal cavities (620 rubles).
• Vazonit - tablets based on pentoxifylline, dilate blood vessels, improve nutrition, oxygen supply to rectum tissues, prevent thrombosis of hemorrhoids (350 rubles).

Replacing Detralex tablets for hemorrhoids with analogues is the prerogative of the doctor.