Which product is better, “Anaprilin” or “Concor”

Composition and release form

The drug "Concor" is available in tablet form. The active substance is bisoprolol hemifumarate. Auxiliary components are also used that enhance its effect.

One tablet contains 2.5 mg or 5 mg of the active element.

The shape of Concor tablets resembles “hearts”

Pharmacological properties

The drug "Concor" is part of the group of selective beta-blockers. The active substance of the drug does not affect cell walls and does not reduce the myocardium’s need for oxygen. The drug helps reduce the concentration of renin in the blood and stabilizes the heart rhythm.

Thanks to this effect, the medication produces the following effects:

• Antianginal.
• Hypotensive.
• Antiarrhythmic.

"Concor" has a prolonged action. The result of the intake is stored for a day. Improvement in the patient's well-being is observed after 3-4 hours.

What is best to take to prevent atrial fibrillation?

The effect of any drug is directly dependent on what is included in its composition and how clearly patients follow the recommendations for use. As for Concor, doctors advise taking it orally in the morning, 1 tablet, with a small amount of water. It is noted that taking the medicine does not depend on when a person eats.

04.11.2014, Vyacheslav, 63 years old

Medicines taken: Cardoron, Concor, Hartil, Thrombopol, Diabeton MV

Complaints: Atrial fibrillation, enlarged right atrium and left ventricle.

What is better to take for the prevention of atrial fibrillation, Cardoron or propanorm. Thank you

Beta-1 blockers are great for lowering blood pressure and improving the functioning of the cardiovascular system in general. A good drug in this segment is Concor.

The medicine helps stabilize blood pressure, and also has antiarrhythmic and antianginal effects (eliminates symptoms of coronary heart disease).

The medication is available in the form of tablets for oral use. There are tablets with 2.5 mg, 5 mg and 10 mg of the active ingredient. The price of the medicine in the pharmacy is about 150-400 rubles for a package of 30 tablets (the cost depends on the amount of active ingredient in the tablet).

https://www.youtube.com/watch?v=So7Rf1F2fhQ

Arterial hypertension is the most common pathology of the cardiovascular system. Unfortunately, it is impossible to cure the disease, but it is quite possible to stabilize the patient’s condition.

For this purpose, medications with a pronounced hypotensive effect are used. Beta-1 blockers are widely used. One of the most effective drugs in this segment is Concor.

Doctors are often asked the question, does Concor lower blood pressure or not? Of course, it reduces, because the medication has a pronounced hypotensive effect. Patients also have a question: Does Concor reduce blood pressure or just pulse? The drug has a pronounced antiarrhythmic, antianginal and hypotensive effect, so when taking the tablets, both blood pressure and pulse are stabilized.

Let's consider the principle of action of the medication. So, it includes:

1. The active components are bisoprolol hemifumarate and bisoprolol fumarate (ratio 2:1).
2. Excipients: crospovidone, magnesium stearate, microcrystalline cellulose, silicon dioxide, calcium hydrogen phosphate, corn starch.
3. The composition of the shell is hypromellose, yellow iron oxide, dimethicone, macrogol 400, titanium dioxide.

The active components reduce the activity of the sympathoadrenal system by blocking beta-1 adrenergic receptors of the heart. The substance has a hypotensive effect by reducing cardiac output and inhibiting the secretion of rhinin. In addition, the active components affect the baroreceptors of the carotid sinus and aorta.

The advantage of the drug is the fact that its active components have low affinity for beta-2 receptors of the smooth muscle structure of the bronchi, blood vessels and endocrine system. Due to this, when using the medicine, it is possible to avoid effects on glucose metabolism, bronchi and peripheral arteries. Long-term use of Concor helps reduce increased peripheral vascular resistance.

In patients with coronary artery disease and chronic heart failure, the active components help reduce the number of heart contractions. The substances also reduce the stroke volume of the heart, myocardial oxygen demand and ejection fraction.

Indications

The drug "Concor" is used in the treatment of such pathologies as:

• Chronic form of heart failure.
• High blood pressure.
• Attacks of angina.
• Heart rhythm disturbances.

The drug also showed itself well in preventing the development of heart attack and cerebrovascular pathologies.

In case of cardiac dysfunction, the drug “Concor” is prescribed.

What is better – Anaprilin or Atenolol?

Atenolol is a medication prescribed for hypertension and other diseases of the cardiovascular system. It also falls under the beta blocker category. It is often used to quickly and effectively normalize blood pressure.

Atenolol tablets 0.1 g and 0.05 g

The drug is highly effective for attacks of heart pain. It is also often prescribed as a preventative measure for myocardial infarction. It is known that it has other indications for use: sudden panic attacks, high activity of the endocrine system, as well as strong and uncontrollable emotional overexcitation.

It is worth noting that the medicine is considered somewhat outdated. This is explained by the fact that it often provokes the appearance of undesirable side effects, thereby causing various metabolic disorders, in particular in the functioning of the pancreas. As a rule, this can lead to the onset of diabetes.

We suggest you read: Anaprilin how to drink with blood pressure

Side effects

When treated with the drug "Concor" the following adverse reactions of the body are possible:

• Headache.
• Sleep disorders.
• Deterioration in performance.
• Dyspnea.
• Cough.
• Visual impairment.
• Increased gas formation.
• Stool disorders.
• Nausea.
• Failure of erectile function in men.
• Collapse.
• Bradycardia.
• Allergic reaction.

If side effects occur, it is necessary to replace the drug with an analogue or adjust the dose.

Cough is one of the side effects of the medication

Comparison of safety of Concor and Anaprilin

The safety of a drug includes many factors.

At the same time, in Concor it is quite similar to Anaprilin. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing the metabolism of Concor, as well as Anaprilin, we look at which organ is the metabolizing organ and how critical the effect on it is.

The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Concor does not have any risks when used, just like Anaprilin.

Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Concor and Anaprilin.

Contraindications

It is forbidden to use Concor tablets for cardiac arrhythmia if the patient has such diseases as:

1. Low blood pressure.
2. Bradycardia.
3. Bronchial asthma.
4. Impaired blood circulation in the body.
5. Kidney pathologies.
6. Malignant neoplasms.

During pregnancy, the drug can be taken only as prescribed by a doctor.

Under no circumstances should the medication be used for atrial fibrillation, which is complicated by bronchial asthma.

The bronchi contain beta-adrenergic receptors, which Concor can influence. As a result, negative consequences may occur.

Medicine Concor for cardiac arrhythmia

Currently, arrhythmia is one of the most common heart pathologies, which complicates the lives of many people.
The essence of this disease is that it disrupts the heart rhythm, which, of course, can negatively affect the body. Concor is extremely popular today for cardiac arrhythmia - a medication that belongs to the antiarrhythmic class and has a very wide range of applications. Next, you will learn about the advantages of this drug and why it is so popular.

Concor tablets are a medication designed to normalize the functioning of the cardiovascular system.

The main active compound is bisoprolol fumarate. In addition, each tablet contains additional excipients (silicon dioxide, corn starch, calcium), which have a positive effect on the body and promote proper absorption of the drug.

It is important that this medicine has an affordable price, so anyone can purchase it, even with an average income.

Reception for arrhythmia

Despite the fact that this medicine is a beta-blocker, it has no effect on cell membranes and sympathomimetic activity. During treatment with this medication, the patient’s body is more saturated with oxygen, and the need for it decreases. In addition, the use of Concor helps to reduce renin activity in plasma.

Since this drug has antiarrhythmic and antianginal effects, many doctors recommend it as one of the best remedies during attacks.

Important! Since this medicine is quite active and effective, it should not be abused; during use it is very important to strictly adhere to the dosage.

Effect on the heart

Many people suffering from cardiac pathologies are worried whether the drug for cardiac arrhythmia Concor actually helps or is it just another advertising ploy. To be fair, it should be said that the majority speak only positively about these pills, because taking them allows you to achieve the following effects:

• decreased blood pressure;
• reducing the likelihood of developing ischemia;
• normalization of heart rate.

From all of the above it follows that this medication really has a complex effect and is able to actively resist a variety of types of arrhythmia, including it will be effective for atrial fibrillation. In addition, Concor is an excellent medicine for the prevention of diseases accompanied by damage to the heart muscle.

The effect of a particular drug on the body depends on what exactly is included in its composition and how competently the patient takes it. As for Concor, there will definitely not be any difficulties with it. But before you begin active treatment, be sure to carefully read the attached instructions.

Most cardiologists advise taking this medicine one tablet at a time in the morning, and they should not just be swallowed, but washed down with water. You can take them regardless of meals.

Since the tablets are coated with a special protective coating, they do not have any pronounced taste, which is extremely important for many patients.

Prescription of medications is carried out only by a cardiologist after conducting a full course of clinical studies. Self-medication in this case is dangerous and can result in fatal consequences. To combat the disease, complex therapy is used, which includes not only taking medications, but also adjusting the diet. The use of tablets often allows you to get rid of arrhythmic symptoms and prepares the body to attack the root causes of the disease.

From this article you will learn: what antiarrhythmic drugs exist, which medications are best suited in each specific case of arrhythmia.

Drug treatment of arrhythmia is the main method of treating this disease. In 90–95%, antiarrhythmic drugs can either completely eliminate arrhythmia or reduce its severity. They are equally effective both in emergency care and in systematic use aimed at preventing repeated rhythm disturbances. But in order to achieve maximum treatment results, it is important to know which drugs should be used in certain cases.

Below is a list of the most effective and safe medications that are most commonly used to treat cardiac arrhythmias (in order of decreasing effectiveness):

1. Potassium channel blockers - Amiodarone (its analogues Cordarone, Aritmil).
2. Beta blockers – Metoprolol (Corvitol), Bisoprolol (Concor), Nebivalol.
3. Calcium channel blockers – Verapamil (Isoptin, Finoptin).
4. Local anesthetics – Lidocaine, Novocainamide.
5. Drugs of different groups:

• cardiac glycosides - Strophanthin, Korglykon, Digoxin;
• medicines containing potassium - Panangin, Asparkam.

The selection, prescription of antiarrhythmic drugs and monitoring their effectiveness are carried out by a cardiologist, but also by a general practitioner and family doctor.

Among all drugs for the treatment of arrhythmia, amiodarone is considered the number one treatment for any heart rhythm disturbances. It is equally suitable for use in emergency mode, when the patient urgently needs to relieve an attack, and for maintenance treatment, preventing repeated heartbeat interruptions.

Drug interactions

The drug "Concor" may interact with other medications, thereby causing negative consequences. The following dangerous combinations are possible:

1. When taken simultaneously with antihypertensive drugs, their therapeutic effect is aggravated.
2. When combined with alpha-methyldopa, reserpine, clonidine and digitalis, a sharp decrease in heart rate is observed.
3. Combination with diltiazem or verapamil helps lower blood pressure, provokes the occurrence of arrhythmia, and the development of heart failure.
4. In combination with sympathomimetics, the effectiveness of the drug "Concor" is reduced.
5. When taken simultaneously with nifedipine or rifampicin, the therapeutic effect of Concor is reduced.
6. When combined with ergotamine, changes in blood pressure occur.
7. Together with insulin intake, the hypoglycemic effect increases.

These drug interactions must be taken into account when treating ari.

Concor does not combine with all medications, so you should tell your doctor if you are taking them.

Application of Concor

Whatever the doctor prescribes Concor for, you need to take it before breakfast, without chewing.

Single dose - 0.5-1 tablet (up to 5 mg). If necessary, it is increased to 10 mg. The maximum daily dose is 20 mg. As for patients with impaired renal or liver function (mild to moderate), dose adjustment is not necessary for them.

Contraindications

There are many contraindications to the use of Concor, including:

• acute heart failure;
• cardiogenic shock (one of the most severe complications of myocardial infarction);
• atrioventricular block (II degree and higher), as well as sinoatrial block;
• bradycardia;
• severe form of chronic obstructive pulmonary disease;
• peripheral circulatory disorders (in later stages);
• Raynaud's syndrome;
• both malignant and benign pheochromocytoma (tumor of adrenal tissue);
• metabolic acidosis (acid-base imbalance), etc.

The drug is not prescribed to small children; and if it is used with caution during pregnancy, then during breastfeeding it is generally contraindicated. It is also not used for those who are hypersensitive to the active component of the drug - bisoprolol.

Side effects and overdose

(addiction, death) The drug has a fairly extensive list of side effects. Among the undesirable consequences of taking Concor may be:

• general fatigue;
• muscle weakness;
• dizziness and headache;
• hallucinations;
• conjunctivitis;
• bradycardia (however, it is rare);
• orthostatic hypotension;
• dyspnea;
• diarrhea or constipation;
• nausea;
• severe pain in the abdominal area;
• violation of potency;
• allergic reactions (itching, redness of the skin), etc.

Symptoms of overdose are usually:

• AV block;
• bradycardia (one of the types of heart rate disorders);
• severe decrease in blood pressure;
• bronchospasms;
• heart failure;
• hypoglycemia (low glucose levels).

If an overdose is suspected, the drug is immediately stopped, symptomatic therapy is started immediately: for bradycardia, atropine is administered intravenously, for a decrease in pressure - plasma replacement and vasopressor drugs, in case of exacerbation of chronic heart failure - diuretics, for bronchospasm - bronchodilators, etc.

Compatibility with other drugs

Taking other medications simultaneously with Concor may affect its effectiveness. Even if you are taking over-the-counter medications, you must tell the doctor prescribing Concor about this. It is undesirable to combine this drug with:

• class I antiarrhythmic drugs - lidocaine, disopyramide, propafenone (in combination with bisoprol they can reduce atrioventricular conduction of the heart);
• centrally acting antihypertensive drugs - methyldopa, clonidine (this combination will lead to a decrease in heart rate and vasodilation), etc.

With great care, Concor is combined with such drugs as:

• class III antiarrhythmic drugs - amiodarone (together with bisoprol they can increase atrioventricular conduction disturbances);
• dihydropyridine derivatives - amlodipine, for example (they increase the risk of developing arterial hypotension);
• hypoglycemic agents;
• general anesthesia (they increase the risk of cardiodepressive effects);
• mefloquine (combination with it may increase the risk of bradycardia);
• monoamine oxidase inhibitors (this may well cause a hypertensive crisis), etc.

We tried to explain in as much detail as possible in this article what Concor medicine is taken for. Do not forget that before using it, it is best to check with your doctor whether it can be combined with those medications that you are already taking.

Analogs

If for some reason the Concor medication is not suitable for the patient, the doctor can change it to an analogue.

Please note that Atenolol and Concor have different active ingredients

The most popular means are:

1. "Atenolol."
2. "Nebilet."
3. "Tenormin."
4. "Vasocardin".
5. "Prinorm."

Only the attending doctor can select an analogue. When replacing, you need to take into account many nuances that the average person does not know about. If prescribed incorrectly, there is a high risk of developing unintended consequences.