Concor is indispensable in the treatment of hypertension, ischemia, and some cardiac pathologies. The duration of treatment lasts from several weeks and can last for years.
The drug has a long-term effect without accumulation of the active substance in the body, the therapeutic effect remains as long as it is taken. Therefore, the question of how to stop drinking Concor is relevant for many patients.
Composition and action
Use is indicated for patients with arterial hypertension, angina pectoris, chronic heart failure, and arrhythmia. The use of various pathologies, including hypertension and ischemia, in complex therapy is not excluded.
Concor prevents the risk of recurrent heart attack and complications of hypertension. The main effect is to constantly adjust blood pressure and heart rate.
Concor tablets
The active substance is bisoprolol, a selective beta blocker. The action is to protect the heart from adrenaline and other catecholamines. The reaction occurs only to the work of the heart muscle, without affecting other organs. Bisoprolol blocks stimulating impulses of the central nervous system to the heart.
If necessary, ACE inhibitors and diuretics are prescribed. Concor does not affect male potency or blood sugar levels.
Dosage form: tablets 5 and 10 mg. The exact dosage is calculated individually, taking into account daily heart rate, blood pressure, the patient’s intake of other medications, as well as the general state of health.
Concor is available only by prescription. Self-medication with adrenergic blockers is unacceptable!
Interaction with other drugs
Most antihypertensive drugs potentiate the hypotensive effect when used together; the strength of the combination can significantly exceed their effect individually and cause severe acute hypotension.
Concor should not be combined with clonidine, as well as with other drugs with central action. The hypotension they cause can cause acute heart failure.
The combined use of Concor with antiarrhythmic drugs enhances their negative effect on the conduction of excitation in the heart muscle and can cause bradycardia and reduce the strength of muscle contractions of the heart. Concor should not be taken if used:
- Lidocaine;
- Verapamil;
- Diltiazem.
The interaction of Concor with other drugs requires increased attention when used with many drugs: amiodarone and other antiarrhythmic drugs, anesthetics, adrenergic blockers for local use, amlodipine, cardiac glycosides.
Non-steroidal anti-inflammatory drugs can weaken the hypotensive effect of bisoprolol, so you should not take Concor with diclofenac, nimesulide or ibuprofen - this may be accompanied by an increase in blood pressure.
You can take Concor while using herbal-based sedatives and antihypertensive drugs.
Concor is a beta adrenergic blocker, it targets the blocking of beta adrenergic receptors in the heart muscle.
Its main analogues include:
- Bidop;
- Tirez;
- Corbis;
- Bisomore;
- Aritel;
- Biol;
- Almost all variations of Bisoprolol.
Its main purpose is to reduce the number of heart contractions and, accordingly, reduce the amount of oxygen required by the organ. The speed of impulse transmission is significantly reduced and the rhythm of the organ is normalized.
This is a drug that aims to reduce a person’s blood pressure; in other words, it dilates the arteries through which blood flows. Sometimes it is prescribed in the presence of angina and failure.
The most important rule: the volume and dose are prescribed strictly by the attending physician, taking into account individual characteristics and the specific situation. Therefore, taking into account all the side factors that will be described below, you must understand that self-medication is not an option; you need control and consultation with a doctor.
The drug has been used for a fairly long period, and even reviews say that it is impossible to abruptly interrupt the course, this must be done smoothly, gradually. Each certain period it is necessary to reduce the dose, and therefore the load on the body, without harming it. The doctor should also reduce the dosage.
Main indications for use:
- Persistent high blood pressure.
- Ischemic diseases of the heart muscle, malnutrition.
- Chronic heart failure.
Concor is also prescribed for vegetative-vascular dystonia, which results in organ damage. It must be treated with psychophysical methods, without involving the use of drugs, then why is Concor prescribed? The thing is that it is aimed at reducing the force of interaction between the heart and the controls; it turns out that with any load on the body, the heart muscle will produce a different reaction.
Like any drug, Concor has many contraindications for use, reviews confirm this fact:
- Individual intolerance to components.
- Allergic reaction to any adrenergic blockers.
- State of shock, enduring severe stressful situations, as cardiac output decreases.
- The presence of chronic cardiovascular failure in the stage of decompensation.
- Very low blood pressure, anything below 90/60 (hypotension).
- Tablets are not prescribed for a fixed, reduced heart rate, since it already reduces the beat rhythm, thereby inhibiting the automatism of the organ.
- If there is sinus block syndrome or weakness in the node.
- If there is 2-3 degree atrioventricular block, but provided that there is no pacemaker.
- The presence of lung disease, in combination with bronchospasms (asthma, bronchitis) also prohibits taking the drug.
- In case of deformation of peripheral vessels leading to contraction of arterioles (for example, Raynaud's syndrome), prescribing the drug is strictly prohibited.
- Not recommended for use by children under the age of majority.
All the described contraindications indicate that Concor tablets are primarily a chemical modification that can cause harm to the body, and only then a drug.
Compatibility
Concor is compatible with amlodipine, nifedipine and other calcium ion antagonists. Hypertensive patients are recommended to use Concor with Amlodipine.
Pharmacists have synthesized a combination drug Concor AM containing both active ingredients; it is indicated only for patients with hypertension.
Amlodipine tablets
Combination use with other antihypertensive drugs is possible: Lozap, Noliprel, Cardiomagnyl, Capoten. Combined use occurs during complex therapy, during gradual withdrawal of the drug. In such cases, you should not violate the dosage and monitor your blood pressure levels before and after taking the medication.
During treatment, it is not recommended to take Ibuprofen, Verapamil and other anti-inflammatory non-steroidal drugs.
For chronic heart failure
For chronic heart failure, this medicine is prescribed only after passing the mandatory titration stage and as part of constant medical supervision. For treatment with the drug in question, preliminary tests of the patient’s condition are carried out, which should show the need for Concor therapy. If within six weeks heart failure has not developed into acute forms, then the patient can be prescribed treatment with Concor. Among other things, this medicine can be prescribed to patients if previously prescribed medications did not provide the desired therapeutic effect that can be achieved with the help of this remedy.
Treatment with this medicine is long-term. If there is a need for a break, it is carried out, but the resumption must proceed in compliance with all required standards. Therapy is never abruptly interrupted when a patient develops coronary artery disease. In such a situation, the amount of medication is gradually reduced. Independent adjustments to the dosage and use of tablets are not recommended; all decisions should be made only by the cardiologist monitoring the patient.
How to take it correctly?
Concor must be taken daily, once a day. The time (morning or evening) will be determined by the doctor after daily monitoring of blood pressure. Take without reference to meals; the tablet can be broken in half, then swallowed without chewing. Consumption at the same time improves the quality of treatment and enhances the effect of the active substance.
Violation of the pattern of use and unauthorized refusal of therapy lead to the following consequences:
- hypertensive crisis;
- heart failure may progress to the terminal stage;
- heart attack;
- stroke.
After stable normalization of blood pressure, treatment cannot be interrupted without permission, even for a day, since after bisoprolol is removed from the body, the blood pressure will increase again.
Depending on the diagnosis, the dosage of Concor and related medications differ. The exact dosage must be prescribed by a cardiologist; self-medication can cause deterioration of the condition, heart attack, stroke, and lead to death.
Overdose: what will happen?
An overdose of the drug provokes hypoglycemia, which is treated with intravenous glucose solution.
If the patient has taken an excessive dose of Concor, then unpleasant symptoms are likely. Bradycardia may often develop or blood pressure may drop significantly. In this case, you need to immediately stop the medicine and carry out symptomatic treatment, which will be prescribed by the doctor. When an overdose leads to bradycardia, Atropine is injected into the vein. It rarely happens that Concor increases blood pressure or provokes hypoglycemia, which is treated by administering a glucose solution.
Contraindications and side effects
Concor is prohibited for use by pregnant and lactating women, as well as people under 18 years of age.
Prescription is contraindicated for those in shock, patients with bronchial asthma, hypotension, psoriasis, bradycardia (pulse below 50), pheochromocytoma, and those with decompensated heart failure.
Intolerance to other adrenergic blockers also applies to Concor. The drug is contraindicated in persons with severe depression.
Patients with chronic liver dysfunction, renal failure, diabetes mellitus, and congenital heart disease are prescribed a dose after additional consultation with a doctor.
In the first week of treatment, patients most often complain of the following side effects:
- drop in heart rate;
- a sharp decrease in blood pressure;
- deterioration of heart failure;
- dizziness, headaches;
- weakness, drowsiness;
- joint pain;
- sleep disorders;
- intestinal problems, nausea.
To reduce or completely eliminate side effects, the attending physician may prescribe other antihypertensive drugs, possibly reducing the dose for a short time until the condition improves.
Among the side effects, bronchospasms are sometimes noted. Since bisoprolol enhances muscle contraction, it is prohibited for pregnant women, since there is a possible risk of miscarriage or premature birth, in addition to the risk of developing hypotension in the fetus and other consequences due to decreased blood flow in the placenta.
When is it better not to take medicine?
You should not use the drug "Concor" with normal blood pressure, since often after taking the pills it drops significantly to critical levels. Avoid taking the drug in the following cases:
- individual intolerance to the active and auxiliary components included in Concor;
- acute manifestation of heart failure;
- cardiogenic shock;
- weakened sinus node functions;
- sinoarterial blockade;
- severe form of hypotension;
- a clear manifestation of bradycardia;
- severe symptoms of bronchial asthma;
- metabolic acidosis;
- impaired functioning of peripheral arterial blood flow;
- formation of pheochromocytoma;
- children under 18 years of age.
Habituation and Dependence
Treatment with beta blockers always has a long duration.
Increasing or decreasing the dosage depends on the patient’s well-being and the manifestation of side effects. In the first days, changes in dosage are possible: deterioration of the condition, decrease in pressure up to a hypotensive crisis, low heart rate.
As these symptoms weaken or intensify, the dose is adjusted and concomitant therapy is administered. Beta blockers do not cause drug dependence on bisoprolol. Constant use and regular increase in dosage are considered addiction.
Concor should not be stopped abruptly, especially for patients with ischemia. There is no universal cancellation scheme. If side effects increase, the attending physician should give recommendations on how to discontinue Concor without danger to the patient’s condition.
Discontinuation of tablets should occur gradually with a decrease in the daily dose under the supervision of a physician; blood pressure and pulse should be monitored.
The minimum period for dose reduction is a week.
A common scheme looks like this: the daily dose is reduced by a quarter (1.25 mg).
In the absence of a pronounced exacerbation of the disease, deterioration of the condition, or side effects, after 7 days the dose is reduced by the same amount, up to complete refusal.
During the process, the patient should be supervised, physical activity should be reduced to a minimum, and, if necessary, additional antihypertensive drugs should be taken to prevent the development of complications and exacerbations.
Concor: withdrawal syndrome
It has not been scientifically proven, but there is an opinion that long-term use of Concor can cause depression. Beta blockers do not cause depression, but the process of drug withdrawal can provoke its development against the background of deterioration in well-being.
People with chronic heart disease may experience “withdrawal syndrome” after stopping use. The likelihood of development depends on the course of the disease, and not on the duration of use.
Cancellation of Concor usually causes the following consequences:
- arrhythmia;
- a sharp increase in pressure with the possible development of a hypertensive crisis;
- worsening of angina pectoris;
- tachycardia over 90 at rest;
- heart failure.
These symptoms can be relieved by taking other adrenergic blockers, calcium channel blockers, angiotensin-converting enzyme inhibitors and other drugs recommended by the cardiologist.
Psychological disorders associated with the withdrawal of Concor have other causes related to the nervous system and moral state of the patient.
Indications for use
Concor tablets are prescribed by cardiologists if the patient has:
- persistently elevated blood pressure or hypertension;
- ischemia;
- angina pectoris;
- increased production of electrical impulses by the sinus node;
- malfunction of the mitral valve;
- persistent increase in the amount of thyroid hormones;
- heart failure.
You should not take Concor if you have low blood pressure. But if a patient is diagnosed with hypertension and a strong decrease in blood pressure readings is an isolated phenomenon, the medicine is taken according to the usual regimen.
Concor is taken for angina pectoris
Analogs
Concor analogues also contain bisoprolol. There are two types of analogs based on the place of production:
- Russian (Aritel, Biprol, Bisoprolol, Niperten);
- foreign (Bidop, Bisogamma; Bisoprolol-Teva; Cordinorm, Coronal, Biol).
Biprol tablets
The main differences are the bisoprolol content, the manufacturer, and the price. The selection of a suitable analogue, if necessary, requires the doctor to be puzzled.
Self-selection of a drug without indications or medical advice can provoke a deterioration in health, including heart attacks, strokes, and possible death.
Other people's experiences
From discussions on medical forums, it seems that many people mistakenly believe Concor is addictive.
Among the recommendations on how to cancel Concor, almost everyone writes that the process took a long time and strictly under medical supervision.
Concor and analogues are strictly prohibited from being used occasionally as a means of emergency therapy; this is what determines the duration of treatment and the demanding regimen of use.
Patients write that they refused Concor due to constant weakness and depression. Others were put off by the annotation: a list of contraindications and side effects.
Doctors say that stopping Concor and other beta blockers leads to deterioration in health. If the regimen is followed and there is no sensitivity to bisoprolol, the treatment is effective within the first days of use.
Dependence on Concor manifests itself not on a physiological, but on a psychological level. However, independent changes in dosage and number of doses will worsen the course of the disease.
Video on the topic
About the nuances of using Concor and Biseptol for hypertension and cardiovascular diseases:
Compliance with medical recommendations, monitoring your pulse and blood pressure is the key to successful treatment. When the question arises of how to quit Concor, medical supervision, discipline and timely intake of the necessary medications will make it easy to replace it with another beta blocker without the occurrence of “withdrawal syndrome”.
The information on the MyMedNews.ru website is for reference and general information, collected from publicly available sources and cannot serve as a basis for making a decision on the use of medications in the course of treatment.
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