The antiarrhythmic drug “Asparkam” for blood pressure is used in cases where it is necessary to reduce high blood pressure levels. This medication normalizes the balance of anions and cations, compensates for the lack of magnesium and potassium in the body, helping to prevent many pathologies of the cardiovascular system. Asparcam should be used for high blood pressure strictly in accordance with the therapeutic regimen prescribed by the doctor. It is better not to self-medicate and undergo therapy under medical supervision.
Compound
Asparkam is available in the form of tablets and solution for injection. The package contains 50 tablets or 10 ampoules of 5, 10 ml.
- Each tablet contains 0.2 g of potassium and magnesium, as well as excipients for the cachet.
- Asparkam solution contains anhydrous magnesium aspartate – 40 mg and potassium – 45 mg. This is equivalent to 3 mg of pure magnesium and 10 mg of pure potassium. In addition, the injection form contains sorbitol and water.
Potassium ensures the passage of nerve impulses, exhibits diuretic properties and plays a major role in muscle contraction. Magnesium is responsible for enzyme activity, participates in ion transport and cell growth.
The mechanism of action is to correct metabolic processes with potassium and magnesium. These elements easily overcome the cell membrane and replenish the deficiency of microelements lost due to time or pathological changes. A normalized electrolyte balance leads to a decrease in myocardial conductivity, dampens its excitability and allows the electrical impulses of the cardiac conduction system to work in the usual manner.
At the same time, metabolic processes improve, the susceptibility of the myocardium to cardiac glycosides becomes better, since their toxicity drops sharply. The coronary vessels also respond to these changes, since the normal rhythmic contractility of the heart allows them to provide optimal blood supply to organs and tissues with nutrients and oxygen.
Magnesium ions activate ATP, which balances the flow of sodium into the intercellular space and potassium into the intracellular space. A decrease in Na+ concentration inside the cell blocks the exchange of calcium and sodium in the smooth muscles of blood vessels, which automatically relaxes them. An increase in K+ stimulates the production of ATP - a source of energy, glycogen, proteins and acetylcholine, which prevents cardiac ischemia and cellular hypoxia.
Asparkam enters the bloodstream through the digestive tract, and from there, in the form of asparginate, into the myocardium, where it begins to work to improve metabolism.
Mildronate
Manufacturer: Grindeks (Latvia)
Release form: tablets
Active ingredient: meldonium
Mildronate belongs to the group of metabolic agents of synthetic origin that improve metabolism. The drug actively removes toxic substances from cellular structures, tones and protects them from damaging external and internal agents.
Mildronate, due to its properties, has a wide range of indications and is used for diseases of various body systems.
Properties
They are caused by the combined effect of potassium and magnesium on the heart muscle and help restore it after a heart attack. K+ improves the contractility of the heart, reducing excitability and improving muscle conduction. It expands the lumen of the great vessels of the heart. Magnesium stimulates the synthesis of amino acids necessary to compensate for the defect in muscle tissue and stimulates cell division, promoting rapid regeneration.
These properties are used in the treatment of glaucoma and high intracranial pressure. Normalization of metabolism and electrolyte balance relieves almost all negative symptoms associated with vascular overload. A side effect is accelerated muscle growth, which has proven important for athletes. Therefore, Asparkam is quite popular in strength sports.
Do you still think that it is difficult to cure hypertension?
Judging by the fact that you are reading these lines now, victory in the fight against pressure is not yet on your side...
The consequences of high blood pressure are known to everyone: these are irreversible damage to various organs (heart, brain, kidneys, blood vessels, fundus of the eye). In later stages, coordination is impaired, weakness appears in the arms and legs, vision deteriorates, memory and intelligence are significantly reduced, and a stroke can be triggered.
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Potassium and magnesium
Cardiologists constantly talk about the importance of these microelements. There is nothing surprising about this. The rhythm of heart contractions is determined by the quality of the conduction system of the myocardium, in which impulses are generated independently and, passing through bundles of special nerve fibers, activate the periodicity of contraction of the atria and ventricles in a certain sequence. The normal conductivity of these fibers depends on the concentration of magnesium and potassium in them.
The heartbeat is normal, which means the person feels good, since each organ receives appropriate nutrition and oxygen on time and with a clear sequence. With a lack of magnesium, problems begin in the coronary vessels. They soften and become wide. As a result, the blood slows down, the organs begin to experience discomfort, and the patient begins to feel worse.
The opposite effect is observed with excess potassium: the coronaries become fragile and narrow. But this also brings nothing but trouble to the bloodstream, since blood cannot enter the main lines in normal quantities and be pumped to the organs. The loss of magnesium by cells, its release into the intercellular space entails the destruction of complex carbohydrates, and hyperkalemia occurs.
Magnesium takes part in all metabolic processes without exception. It is a catalyst for cell division, RNA synthesis, and provides the laying of hereditary information. But if its concentration decreases, the cell membrane becomes an insurmountable obstacle for the trace element. Magnesium Asparkam helps get into it with an additional amount of the element.
There are pitfalls here. An overdose of the drug is fraught with hypermagnesemia, and this is the cause of cardiac arrest. Therefore, self-prescription of a “harmless” drug is unacceptable.
The concentration of potassium and magnesium in the cell is especially important during pregnancy. They ensure stable development and growth of the fetus. But Asparkam is prescribed to pregnant women with great caution, preferring German Panangin, a vitamin for the heart. Symptoms of overdose are fatigue and dysuria.
Another nuance: a lack of potassium changes nervous excitability, and a deficiency of intracellular magnesium causes an imbalance in the generation and expenditure of energy, which stimulates convulsions, numbness of the limbs, and lethargy.
Main symptoms of hypertension
At first, the symptoms are barely noticeable:
- weakness in the body;
- dizziness;
- fast fatiguability;
- sleep problems;
- numbness of fingers;
- feeling as if “flies are flashing before the eyes.”
Heart disease is rarely manifested by high blood pressure alone, so it is difficult not to notice a whole range of symptoms that indicate poor functioning of blood vessels and heart muscle:
- Shortness of breath and lack of air, fatigue from simple physical activity or even climbing stairs.
- Spasms in the heart, periodic chest pain, a feeling of squeezing and the inability to breathe freely.
Periodic chest pain is one of the symptoms of hypertension
Therefore, you should not wait for such symptoms to appear. If hypertension has become a common condition for you, then this condition will not last long, and your health will deteriorate until it is too late. The most sensible decision in such a situation would be to go to the hospital, where using an ECG (electrocardiogram) it will be possible to determine the presence of the disease. Timely diagnosis and a competent course of treatment will help you live a healthy life without disease or risk to the heart.
Primary hypertension (essential) is very common, and a person may often be unaware of high blood pressure until a hypertensive crisis. Symptoms may include:
- chronic elevated diastolic or systolic pressure (more than 140/90 mm Hg);
- nosebleeds;
Nosebleeds may indicate hypertension
Primary hypertension has no apparent cause, such as kidney or thyroid disease. After examining the internal organs, the doctor will draw up a clear picture of what is happening and select an adequate treatment route.
Modern medicine can offer many drugs for high blood pressure, but none of them are recommended to be taken without a doctor’s prescription. You are not able to independently analyze the situation in order to understand the cause of high blood pressure, much less prescribe medications for yourself.
Any drugs have contraindications, composition and mechanisms of action:
- Centrally acting drugs that regulate blood pressure. Medicines in this group can depress the central nervous system and cause drug dependence.
- Angiotensin receptor blockers, which affect the narrowing of vascular walls.
Angiotensin receptor blockers
Indications for taking Asparkam
The main function of Asparkam is the transport of microelements into the cell. The drug is prescribed in the following cases:
- Deficiency of K+ and Mg+ in the body.
- Heart rhythm disturbance.
- IHD, post-infarction condition.
- Ventricular extrasystole.
- Foxglove intolerance.
- State of shock.
- Chronic circulatory disorder.
- Atrial fibrillation.
- Heart failure.
- From 4 months it is recommended in combination with Diacarb to correct intracranial pressure. This combination treats glaucoma, epilepsy, edema, and gout.
Sport
It cannot be said that Asparkam has a significant effect on muscle growth. Therefore, in theory, this is not the drug of choice for sports. But, nevertheless, its popularity among athletes is great. This is explained simply: when gaining extra pounds, athletes eat a large amount of calories in the form of proteins, carbohydrates, and fats. At the same time, microelements account for a very small part of the diet. It is clearly not enough for normal cardiac activity. Moreover, a lack of potassium and magnesium leads to high fatigue due to metabolic imbalances. Asparkam in this case is irreplaceable.
Compact, easy to take and rich in essential K+ and Mg+ preparation:
- Relieves the feeling of fatigue.
- Replenishes micronutrient deficiencies.
- Relieves muscle weakness.
- Makes myocardial function stable.
- Stimulates endurance.
- Prevents AMI and stroke.
Body-building
As for bodybuilding, here Asparkam acts as an excellent metabolite. It is during strength training that its side effect of building muscle mass is in demand. Potassium has a positive effect on the speed of metabolic reactions, magnesium is involved in protein metabolism. In this case, cell growth occurs without fat accumulation and fluid retention in the body. This is a very important point, since during training athletes consume large amounts of water, which washes away microelements. This means that their replenishment becomes an urgent necessity.
Weight loss
The rationality of taking the drug is based on the same already familiar properties of magnesium and potassium. Mg+ is needed by the central nervous system, and K+ helps all muscles in the body. Together they correct the water-salt balance and remove swelling. Because of this feature, Asparkam is used for weight loss: removing fluid from the body allows you to lose weight. At the same time, the amount of fat deposits remains unchanged, so the drug has never been classified as a means of helping to lose weight. Taking it thoughtlessly is dangerous, since it is a metabolite, and metabolism is a very delicate substance. An excess of microelements has undesirable consequences, but in no way accelerates metabolic processes.
What to do if your blood pressure is high
Have you been struggling with HYPERTENSION for many years without success?
Head of the Institute: “You will be amazed at how easy it is to cure hypertension by taking it every day...
What to do if you have high blood pressure - you should discuss this issue with your doctor, in which cases you should try to cope on your own, and when self-medication is contraindicated.
Such situations happen in the life of every hypertensive patient and a first aid kit with the necessary medications should be at hand.
Usually, it is enough to take drugs such as nifedipine (phenigidine, Corinfar) or captopress under the tongue. The effect occurs quite quickly after 15-20 minutes and lasts up to 4-6 hours. In some cases, it is possible to simply take a higher dosage of scheduled medications, if available.
Usually, a single dose of the drug normalizes blood pressure well. However, if after repeated use the numbers remain high and the headache intensifies, chest pain, nausea, vomiting, shortness of breath, fainting or loss of consciousness appear, then it is necessary to urgently call an ambulance, perhaps we are talking about a complicated hypertensive crisis.
For those who know the technique of intramuscular injection, it must be said that one of the most effective and safe methods of reducing blood pressure used in a hospital is the intramuscular injection of dibazole with papaverine, although ambulances usually prefer magnesium sulfate due to the speed of its action.
Contraindications and method of use
There are few contraindications, but they are important:
- Individual intolerance or sensitization of the body.
- Impaired function of the adrenal glands and kidneys.
- Myosthenia.
- Cardiogenic shock.
- Blockade 2-3 degrees.
- Metabolic acidosis.
- ARF and chronic renal failure, anuria.
- Hemolysis.
- Dehydration.
- Age up to 18.
The effect of Asparkam on the body has not been studied in detail. For this reason, it is used with caution during pregnancy and is not prescribed to children. Elderly patients are also at risk, since their metabolism is a priori slowed due to age-related changes. However, for diseases of the cardiovascular system, the drug can be taken without restrictions. The usual method is a couple of tablets three times a day after meals.
The difference is which is better for pressure
The difference is that Asparkam is a domestic analogue of Panangin. The degree of purification of the composition of original pharmaceuticals is higher, so the risk of adverse reactions is lower. Panangin dragees are covered with a protective coating, which makes them easier to swallow. "Panangin" does not irritate the gastrointestinal mucosa during inflammation. It is better to grind Asparkam tablets into powder and add to food.
“Asparkam” is a domestic pharmaceutical product, and therefore its cost is noticeably lower. "Panangin" is produced by the Hungarian concern "Gedeon Richter", therefore the price of the original medicine is higher. "Panangin" is considered safe for use in children. It is impossible to compare which pharmaceutical drug is more effective, since it is necessary to take into account the individual sensitivity and response of the patient to the pharmaceutical drug.
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Side effects
Asparkam has not only positive side effects, but also negative ones. They are visualized by the following symptoms:
Feeling weak, tired, dizzy.
- Muscle weakness.
- Skin rashes.
- Nausea.
- Dyspepsia.
- Dry mouth.
- Bloating.
- Hypotension.
- Hyperhidrosis.
- Dyspnea.
- Vein thrombosis.
In addition, an overdose is possible, which manifests itself:
- hyperkalemia;
- hypermagnesemia;
- crimson cheeks;
- thirst;
- arrhythmia;
- convulsions;
- arterial hypotension;
- heart blockades;
- depression of the respiratory center in the brain.
These symptoms require consultation with a doctor. In general, long-term use of Asparkam requires monitoring of electrolyte levels, because:
- the absolute safety of the drug has not been proven;
- when combined with tetracyclines, iron and fluorine, the medicine inhibits their absorption (the interval between medications must be at least three hours);
- there is a risk of developing hyperkalemia.
Magne B6
Manufacturer: Sanofi (France)
Release form: tablets
Active ingredient: magnesium lactate, pyridoxine hydrochloride
You can replace Asparkam with the combined drug Magne B6. The indication for prescribing this analogue is the presence of a deficiency of this microelement in the body. The product contains vitamin B6, which helps improve the absorption of magnesium in the gastrointestinal tract and its concentration in cellular structures.
Compatibility
It has a different focus. From a pharmacodynamics point of view, combination with diuretics, beta blockers, cyclosporines, NSAIDs, heparin stimulates the development of asystole and arrhythmia. The combination with hormones stops this situation. Potassium ions reduce the negative effect of cardiac glycosides. Magnesium ions – neomycin, streptomycin, polymyxin. Calcium reduces the activity of magnesium, so such drugs must be combined with great caution, according to health indications.
Pharmacokinetics warns about the incompatibility of Asparkam with astringent and enveloping drugs, since they reduce the absorption of the drug in the digestive tube and recommends, if necessary, maintaining a three-hour interval between doses.
Interaction
In large doses, the drug reduces the effect of psychostimulants. Because it affects the pulse, it may indirectly increase the negative effects of beta blockers.
Caffeine is a known purine stimulant.
Advice! It is not recommended to use medications without a doctor's permission. Before using any product, you must consult a doctor. Some substances are contraindicated in certain diseases. The decision to prescribe medications must be made by the doctor.
Video on the topic
Learn more about how to properly treat with Asparkam in the video:
Asparkam is a remedy that enriches the patient’s body with magnesium and calcium. It has a beneficial effect on many systems. The main advantages include reasonable price and high efficiency, which are not so often combined in one medicine. Adverse reactions are rare, and there are quite a few contraindications. Available in the form of tablets and injections.
The information on the MyMedNews.ru website is for reference and general information, collected from publicly available sources and cannot serve as a basis for making a decision on the use of medications in the course of treatment.
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