Captopril is an angiotensin-converting enzyme (ACE) inhibitor drug that lowers blood pressure.
It is used to treat arterial hypertension, chronic heart failure, myocardial dystrophy and diabetic nephropathy.
How to take Captopril tablets (under the tongue or drink) and in what cases is the drug contraindicated? How often can I take Captopril and can I take it every day? Let's figure it out.
Varieties, release form and composition
Captopril is available in several types of tablets for oral use.
| Main substance | Auxiliary components |
| Captopril | Colloidal anhydrous silica, castor oil, lactose, starch |
Varieties of the drug are distinguished by the addition of the manufacturer's abbreviation to the main name. For example:
- Captopril-Vero;
- AKOS;
- Akri;
- Aegis;
- Ros;
- Sar;
- STI;
- UBF;
- FPO;
- Ferein and others.
The manufacturer is given the right to modify the composition of the drug, leaving the main substance unchanged, diversifying the list with auxiliary components. This gives reason to study the indications for use in detail in order to avoid side effects.
Drug interactions
The simultaneous use of Captopril with various medications can cause unpleasant consequences:
- with immunosuppressants and cytostatics - development of leukopenia;
- with NSAIDs - disturbances in kidney function, sometimes - hyperkalemia;
- with drugs used for anesthesia - severe hypotension;
- with medications that contain probenecid. - decreased renal clearance;
- with interferon - severe form of granulocytopenia;
- with orlistat - a decrease in the therapeutic effect of Captopril.
This is not the entire list of drug interactions between the drug and other medications. To avoid harm to health, the patient should inform the doctor about all medications he is taking.
pharmachologic effect
Captopril is a drug from the pharmacological group of ACE inhibitors. Its effectiveness is based on the suppression of enzyme activity, which ensures the conversion of angiothesin I to angiothesin II. This feature allows the blood vessels to maintain their dilated state and, as a result, stabilize blood pressure.
Expansion of the lumen of blood vessels increases the threshold of tolerance to emotional and physical stress, by reducing the load on the heart muscle. Moreover, the active substance does not retain fluid, freeing the patient from additional use of diuretics. This property gives an advantage when choosing an antihypertensive drug.
Indications for use
Captopril is indicated for use in the treatment of the following diseases:
- arterial hypertension (as monotherapy or as part of combination therapy. The drug is most effective in combination with thiazide diuretics, such as Hydrochlorothiazide, etc.);
- congestive heart failure, cardiomyopathy;
- diabetic nephropathy developed in type I diabetes mellitus (used for albuminuria more than 30 mg/day), autoimmune nephropathies (rapidly progressive forms of scleroderma and systemic lupus erythematosus);
- impaired left ventricular function in people who have had a myocardial infarction (applies only if the patient’s condition is stable).
For people suffering from both hypertension and bronchial asthma, Captopril is the drug of choice.
Instructions for use
Most readers are interested in the questions: at what pressure and how to take Captopril? It should be taken at high blood pressure an hour before meals. In this case, it is not allowed to crush the tablets: chew or bite. The drug should be swallowed in its original form with plenty of water.
The dosage of the drug is determined by the attending physician individually.
When starting therapy with minimal doses, monitoring the effective effect of the drug is necessary. Blood pressure is checked using a tonometer every 30 minutes. If necessary, the amount of the drug is increased to the maximum allowable dose of 300 mg/day. It should be noted that increasing the dosage increases the risk of side effects that can lead to undesirable consequences.
General provisions and dosages
| Disease | Drug doses in mg/day | |||
| Start of therapy | Prevention | Maximum | ||
| Hypertension | 25 x 2 | 25 x 2 | 50 x 2 | |
| Chronic heart failure | 6.25 x 2–3 | 25 x 2/3 | 150 | |
| Kidney dysfunction Moderate More pronounced form | 75–100 should not exceed 12.5–25 | |||
| Old age | it is not recommended to exceed 6.25 | |||
| Myocardial infarction | 6.25 x 2 | 12.5 x 3 | 50 x 3 | |
| Diabetic nephropathy | 25–50 x 3 | |||
| Microalbuminuria 30 mg/day | 50 x 2 | |||
| Proteinuria more than 500 mg/day | 25 x 3 | |||
Sublingual application
The drug begins to act only 60 minutes after administration. To provide emergency assistance for high blood pressure, Captopril is dissolved by placing the tablet under the tongue. Within 15 minutes the effect of the drug is noticeable.
Use during pregnancy and breastfeeding
According to clinical studies in animals, the drug has a toxic effect on the developing fetus. Taking the medicine starting from the 13th week led to death and provoked developmental defects. Based on the above, the use of the drug at the first signs of pregnancy requires immediate discontinuation.
The active substance included in the composition tends to penetrate into mother's breast milk, and therefore, if it is necessary to take the drug, the newborn is transferred to artificial feeding.
special instructions
Starting therapy with Captopril requires a full examination and clarification: the concentration of electrolytes, the amount of fluid in the body and kidney function. During treatment the following should be kept under control:
- leukocyte count;
- level of protein concentration in urine;
- creatine value;
- the presence of protein and potassium in the blood.
A complete blood count is performed weekly. If the indicators change, the drug is stopped or its dosage is changed. Diseases in which the drug is prescribed with extreme caution:
- systemic vasculitis;
- diffuse connective tissue diseases;
- taking immunosuppressants;
- bilateral renal artery stenosis.
And also during desensitizing therapy.
Starting to take it often causes a decrease in blood pressure.
In connection with this fact, the start of treatment should be carried out within the walls of the hospital under the supervision of medical workers. Carrying out even minor operations during which anesthesia is administered can also lead to a sharp drop in blood pressure. To avoid complications, patients are required to promptly inform their doctor about the use of the drug.
ATTENTION! Taking Captopril provokes jaundice or gives a false positive reaction to the presence of acetone in the urine. This feature obliges the attending physician to monitor the patient’s health status. In both cases, the medication is stopped.
Impact on the ability to operate machinery
Due to the peculiarity of Captopril to cause dizziness when taking it, work activities associated with increased attention, as well as those requiring a high reaction speed, are not recommended. Driving a car is not recommended.
What does it help with?
Captopril is used for arterial hypertension. Before you start taking the medicine, it is recommended to find out the cause of the increase in blood pressure. Often this condition accompanies some other disease, so you should not self-medicate. The drug must be prescribed by a doctor. The use of the medication is possible at any stage of hypertension.
Captopril as part of complex therapy is prescribed for chronic heart failure. The drug is indicated for left ventricular dysfunction caused by myocardial infarction. Type 1 diabetics suffering from diabetic nephropathy are also recommended to take this medication.
Type 1 diabetics suffering from diabetic nephropathy are recommended to take this medication.
Interaction with other drugs
- The simultaneous use of Captopril with a drug containing lithium derivatives provokes an increase in their concentration in the blood serum.
- The hypotensive effect is reduced by estrogens, retaining sodium ions.
- Combined therapy with the drug Clonidine slows down the hypotensive effect of the drug.
- Use simultaneously with potassium-sparing agents provokes the development of hyperkalemia.
- The use of Allopurinol or Procainamide increases the risk of developing Steven-Johnson syndrome or neuropenia.
- Non-steroidal anti-inflammatory drugs reduce the hypotensive effect.
- Patients concomitantly taking immunosuppressants increase the risk of hematological diseases.
special instructions
The instructions do not say that during treatment you should abandon those activities that require concentration. But you should still be careful. This applies to driving and work related to various mechanisms.
Can I take it during pregnancy and lactation?
During such periods, taking the drug is prohibited.
During pregnancy, taking the drug is prohibited.
Use in childhood
The medication is not prescribed to patients under 18 years of age.
For impaired renal function
For kidney disease, it is not recommended to take Captopril simultaneously with potassium-sparing diuretics and other medications that contain potassium.
For liver dysfunction
Patients with liver disease should take the tablets with caution.
Side effects
| Organ and organ system | Side effects of the drug |
| Heart and blood vessels | sharp decrease in blood pressure, tachycardia, swelling of the legs, chest pain, hot flashes, pallor, cardiogenic shock |
| Breath | dry cough, pulmonary edema, shortness of breath, bronchitis and bronchospasm, pneumonia |
| CNS | dizziness, headache, sensitivity disorder in limbs, drowsiness, blurred vision, sensitivity to light, chronic fatigue |
| Gastrointestinal tract, liver, pancreas | disturbances in taste, dryness and inflammation of the oral mucosa, nausea, loss of appetite, diarrhea, abdominal pain, increased activity of liver enzymes, increased bilirubin, hepatitis |
| Hematopoiesis | decrease in platelet concentration; decrease in hemoglobin level in red blood cells; absence in the blood or a sharp decrease in the number of granulocytes |
| Leather and soft tissues | rash, itching, pemphigus, baldness, shingles, redness of the facial skin |
| Urinary and reproductive systems | kidney dysfunction, poly- and oliguria, impotence |
| Laboratory indicators | In the blood: sodium deficiency, increased potassium levels, upward changes in acidity |
Possible side effects
The cause of side effects during the course of treatment is non-compliance with the dosage prescribed by the doctor, the presence of contraindications for the absorption of the medicine.
The following side effects from using the drug Captopril for blood pressure are identified:
- swelling;
- tachycardia;
- a change in the structure of the blood, expressed in an increase in creatinine with urea, protein is detected;
- the occurrence of diabetic nephropathy;
- renal failure worsens;
- increases migraine headaches;
- dizzy;
- nervous disorders;
- apathetic state;
- cough without sputum, possible pulmonary edema;
- bronchospasms;
- allergic reactions, manifested by itching and various rashes;
- painful condition in the stomach area;
- diarrhea;
- nausea;
- impaired sensitivity of the limbs, manifested by tingling and goosebumps.
An overdose can cause blood pressure to drop sharply, which is also a side effect.
If one or more of the listed side effects is detected, you should seek medical help as soon as possible to further eliminate the side effects.
Overdose
An independent increase in the dose of the drug provokes a sharp decrease in blood pressure. An overdose threatens the patient with cerebrovascular accident and can lead to thromboembolic complications, collapse or myocardial infarction.
In order to prevent irreversible reactions in the patient’s body if the dosage is exceeded, emergency assistance should be provided immediately. For this purpose, the patient should be laid down and given a drug that raises blood pressure until the ambulance arrives. Qualified doctors will continue symptomatic therapy in the hospital, which sometimes requires hemodialysis.
Pharmacological properties of the drug Captopril Sandoz
The drug has antihypertensive and vasodilating properties.
Pharmacodynamics
Captopril helps reduce the production of the hormones angiotensin II from angiotensin I, which reduces the release of aldosterone. This leads to a decrease in blood pressure and stress on the heart muscle.
The drug helps lower blood pressure.
Under the influence of the drug, blood flow in the coronary and renal arteries increases. In patients taking the drug for a long time, blood supply to the myocardium improves.
The drug reduces the risk of developing diabetic nephropathy.
Pharmacokinetics
About 75% of captopril is absorbed from the gastrointestinal tract within a short period of time. But when taking the tablet and food simultaneously, absorption decreases by about 30-40%. The maximum concentration of the active substance in the blood is observed 0.5-1.5 hours after taking the medicine.
The drug is metabolized in the liver. Half-life is less than 3 hours. This time is increased in patients suffering from renal failure.
Analogs
The pharmaceutical industry has developed two types of Captopril analogues:
- containing a similar amount of the main active ingredient;
- containing a substitute for the active substance with a similar spectrum of action.
The first group of generics containing Captopril includes:
- Angiopril-25;
- Blockordil;
- Kaptopres;
- Alkodil;
- Kapoten.
The second group of generic Captopril consists of ACE inhibitors:
- Accupro;
- Amprilan;
- Arentopres;
- Bagopril;
- Hypernik;
- Dapril;
- Diropress;
- Zonixem;
- Irumed;
- Coverex;
- Metiapril and some others.
Mode of application
It is recommended to take the drug approximately one hour before meals, since during this time the absorption of individual components is significantly reduced.
The appropriate dosage should be selected only by the attending physician.
The first dose should start with half of one tablet once a day. Next, you should take the drug in this way: the maintenance dose can be one tablet once a day.
The most pronounced therapeutic effect can be noted only two months after starting to take this drug. The current dose can only be reviewed after six weeks.
If the drug does not cope well with its main task, then you can additionally take Captopril and Hydrochlorothiazide in the form of single drugs.
Price
The cost of the drug depends on the manufacturer and retail outlet. Here are some examples of Captopril prices in Russian pharmacies.
| Dosage of active substance in mg | Number of tablets per package | Price in rubles |
| Captopril 25 Analog from Sandoz | 20 | from 9 to 13 from 85 to 106 |
| Captopril 25 Analog from Sandoz | 40 | from 12 to 29 from 140 to 167 |
| Captopril 50 | 20 40 | from 25 to 50 from 40 to 61 |
Varieties, names, composition
Currently, the drug is available in several of the following varieties:
- Captopril-Vero;
- Captopril Hexal;
- Captopril Sandoz;
- Captopril-AKOS;
- Captopril-Acri;
- Captopril-Ros;
- Captopril-Sar;
- Captopril-STI;
- Captopril-UBF;
These varieties of the drug actually differ from each other only by the presence of an additional word in the name, which reflects the abbreviation or well-known name of the manufacturer of a particular type of drug.
Otherwise, the varieties of the drug are practically no different from each other, since they are produced in the same dosage form, contain the same active substance, etc. Moreover, often even the active substance in the drug varieties is identical, since it is purchased from large manufacturers China or India.
The differences in the names of the varieties of Captopril are due to the need for each pharmaceutical company to register the drug they produce under an original name that is different from others.
Reviews
Reviews published on the Internet are confirmation of the effectiveness of Captopril as a means of providing emergency assistance. However, some patients are still forced to refuse to use the medicine due to pronounced side effects.
Here are some statements from patients:
Expert opinion
Tamara
Site reader
Despite the fact that taking the drug causes dizziness, Captopril is always at hand. He saved me more than once during a hypertensive crisis, providing an almost instantaneous effect. The only bad thing is that the pharmacy requires a prescription from a doctor.
Expert opinion
Peter
Site reader
Tired of constantly high blood pressure. I took almost everything that was sold in a pharmacy without a doctor’s prescription to relieve headaches and survive a hypertensive crisis. Yesterday the attending physician prescribed Captopril and I am amazed at its effect. The pressure returned to normal quite quickly, there were no side effects! I would like to note the complete lack of compatibility with alcohol. You should not take medicine even with a hangover! Remember, this is dangerous!
Expert opinion
Marina
reader
A friend of mine has been taking Captopril for a long time, which was recommended by an emergency doctor. As time passed, he stopped helping. Despite all the persuasion, she refused to go to the attending physician and change the medicine or its dosage, which almost killed her during the next attack of hypertension. The ambulance advised me to take a pill under my tongue and this method really helped. We're going to the doctor tomorrow.
What's the best way to relieve blood pressure?
If your blood pressure suddenly rises, then for a quick effect you need to dissolve the tablet under your tongue. Thus, the decrease in blood pressure will begin within a few minutes, but the effect of the drug will be smooth. Complete normalization of cardiovascular system parameters may occur within a few hours (from four to eight hours).
If half an hour has passed after taking the medicine, and the tonometer readings remain unchanged, then it is better to call an ambulance.
Useful video
You can learn more about the treatment of hypertension, Capoten and Captopril in the video below:
The emergence of inhibitor drugs, which include the one we are considering, Captopril, has made it possible to effectively combat hypertension and cardiovascular diseases. As a rule, they are used not only as emergency aid, but also allow complex treatment, minimizing the risk of heart attack and stroke.
However, it should be remembered that self-medication with Captopril is unacceptable! A visit to a doctor to draw up an individual plan is a must.
Video on the topic
How are Captopril and Capoten taken for hypertension? What is more effective: Capoten or Captopril? How long can you take these medications? Answers in the video:
The information on the MyMedNews.ru website is for reference and general information, collected from publicly available sources and cannot serve as a basis for making a decision on the use of medications in the course of treatment.
MyMedNews.ru
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Captopress or Captopril: which is better?
The drug Kaptopres has analogues in Russia, which are much more affordable. But, nevertheless, many prefer to choose Captopril. Why is he so popular?
Captopril tablets
Most modern medicines, which are analogues of each other, differ in their cost for various reasons, despite the fact that they have a completely identical active substance. Because of this, it is often very difficult for a patient to make a final choice, since he does not understand what the difference is between remedies that are identical at first glance.
Therefore, quite often there is confusion and mistrust in a specialist who prescribes a more expensive medication. In this case, Captopril is an analogue of Captopres in composition, but completely different in price. What is the reason for this?
As you know, the effect of any medicine is based on the active substance that is in its composition. Captopril consists of the ingredient of the same name, which is an ACE inhibitor - angiotensin-converting enzyme. The principle of its action is based on a significant suppression of ACE activity, as well as on the effective elimination of narrowing of veins and arteries.
In addition, Captopril produces the following effects:
- reduces peripheral resistance;
- increases cardiac output;
- significantly dilates blood vessels;
- lowers blood pressure;
- improves the heart's resistance to stress.
But the main active ingredient of Captopress is the same substance that is found in the previous drug - Captopril. Both drugs in question are available in tablets with the same dosage - 25 mg and 50 mg. According to the instructions, they are completely identical both in composition and in effectiveness.
The only difference between the analogue of Captopres called Captopril is that it is less pure, since it contains a large amount of potato starch, lactose, cellulose, talc, povidone and magnesium stearate.
Captopril is cheaper because it contains more additional substances than the active ingredient. Of course, this in no way affects the effectiveness of the drug, but the talc in the composition can cause unwanted side effects.
Contraindications
Kaptopres also has contraindications that you should definitely pay attention to:
- angioedema that occurred during treatment with ACE inhibitors;
- congenital angioedema;
- low content of potassium ions in the blood;
- loss of sodium salts and fluids;
- gout;
- high calcium levels in the blood;
- porphyria;
- pregnancy and lactation;
- excessive release of aldosterone;
- serious and pronounced disturbances in the normal functioning of the organs of the excretory system;
- creatinine clearance;
- bilateral stenosis of the renal large vessels or stenosis of the artery of a single kidney with progressive azotemia;
- severe condition after kidney transplantation;
- lack of urine flow into the bladder;
- disorders that prevent the outflow of blood from the left ventricle;
- high sensitivity to individual components of the drug, especially the main ones;
- partial intolerance to the components;
- serious disruptions in the functioning of the liver, when there is a precomatous state or so-called hepatic coma.
You should not take the drug yourself, as it has a large number of contraindications that you need to pay attention to. It should only be prescribed by your attending physician.
Advantages of the drug
Why is the drug Captopril considered very effective for the treatment of hypertension and heart failure? This is explained by a number of undeniable advantages over similar drugs:
- according to studies, the mortality rate from diseases of the cardiovascular system with regular use of Captopril is significantly reduced;
- the drug lowers blood pressure as effectively as other drugs from the main classes intended to relieve symptoms of hypertension;
- does not pose a danger to elderly patients;
- slows down the development of symptoms of kidney diseases, even those arising against the background of diabetes mellitus;
- does not reduce erectile function in men;
- acts on the body as a whole, providing an antioxidant effect on tissues and blood vessels;
- reduces the risk of malignant tumors many times more effectively than other classes of medications.
In addition to the listed advantages of using Captopril in the treatment of hypertension, the drug is affordable, in contrast to analogues and products with a similar chemical composition. Therefore, patients and doctors have long considered Captopril to be the gold standard in the treatment of hypertension, high blood pressure and pathologies of the cardiovascular system.
Analogues of Captopril
Thanks to the availability of modern analogues of Captopril, doctors prescribe a number of drugs with a similar mechanism of action and treatment results for the treatment of hypertension. Antihypertensive drugs can replace Captopril in the form of:
- generics;
- combination medications;
- synonyms.
A large selection of analogues of Captopril tablets produced by the pharmaceutical industry expands the doctor’s field of activity. This makes it possible to select antihypertensive drugs for different categories of patients with a complicated medical history.
Table of Captopril analogues with prices and country of origin
| Analogue | Price in rubles | Manufacturer country |
| Lorista | 420-450 | Slovenia |
| Enap | 130-190 | Slovenia |
| Losartan | 110-380 | Russia |
| Corinfar | 110-160 | Israel |
| Cordaflex | 150-180 | Hungary |
| Concor | 140-190 | Germany |
| Amlodipine | 50-140 | Russia |
For the treatment of hypertension, you can purchase domestic and imported analogues of Captopril in various price categories in the pharmacy chain, available both with and without a doctor’s prescription.
Lorista
Manufacturer: KRKA (Slovenia)
Release form: tablets
Active ingredient: hydrochlorothiazide, losartan
The analogue of Captopril Lorista is a drug of combined action that gives a hypotensive result. The drug effectively lowers systolic and diastolic blood pressure and controls its levels within 24 hours. The action of the analogue leads to:
- to reduce the load on the heart muscle due to the diuretic effect;
- slowing the development of chronic heart failure;
- increasing physical endurance;
- preventing the development of left ventricular hypertrophy.
The drug has no effect on the number of heart contractions. The medicine is taken 50–100 mg 1 time per day, regardless of meals. The greatest effect from taking the drug is achieved after 3 weeks.
Enap
Manufacturer: KRKA (Slovenia)
Release form: tablets
Active ingredient: enalapril
This is an analogue of Captopril with antihypertensive action, having 1 active substance. Enap has a vasodilating effect, which helps to increase the minute volume of blood flow in the heart muscle and resistance to stress. Long-term use of the drug leads to regression of functional deficiency and its severity.
In case of left ventricular dysfunction, the Enap analog has a positive effect on the dynamics of the process, preventing the development of complications of hypertension (myocardial infarction) and reducing attacks of angina. The initial dosage of the drug is 2.5-5 mg per day, followed by an increase to 10-20 mg in 2 doses per day.
Losartan
Manufacturer: GEDEON RICHTER (Hungary)
Release form: tablets
Active ingredient: losartan
The analogue Captopril Losartan helps reduce the risk of developing chronic heart failure, accompanied by a violation of the muscular structure of the left ventricle. The drug prevents the worsening of hypertension and its consequences such as stroke and myocardial infarction.
Losartan actively reduces blood pressure in patients with type 2 diabetes mellitus due to improved hemodynamics and the condition of the vascular wall of the capillary network. The therapeutic dose of the analogue is 50 mg per day, which can be increased according to indications to 100 mg per day.
Corinfar
Manufacturer: TEVA Pharmaceutical Industries (Israel)
Release form: tablets
Active ingredient: nifedipine
The drug not only provides a good hypotensive effect, but also has a positive effect on various forms of angina. Corinfar helps reduce angina attacks and make them easier. The drug increases blood supply to the heart muscle, especially in the area of ischemia, due to myocardial infarction.
This analogue of Captopril can be used in patients suffering from chronic renal failure. The initial dose of the drug is 10 mg 2-3 times a day. To enhance the therapeutic effect, the dosage of Corinfar can be gradually increased to 20 mg 1-2 times a day.
Cordaflex
Manufacturer: EGIS Pharmaceuticals (Hungary)
Release form: tablets
Active ingredient: nifedipine
An analogue of Captopril, the drug Cordaflex, is prescribed for the treatment of arterial hypertension complicated by coronary heart disease (CHD). The drug actively prevents the development of angina attacks, and is also indicated for Raynaud's syndrome, which develops as a result of impaired vascular tone.
The antihypertensive drug can be used in patients suffering from chronic renal failure, as well as in patients undergoing hemodialysis treatment. The initial dosage of the Cordaflex analogue is 20 mg 2 times a day, which can be increased to 40 mg 2 times a day.
Concor
Manufacturer: MERCK KGaA (Germany)
Release form: tablets
Active ingredient: Bisoprolol
Concor belongs to the group of selective beta-blockers. The drug helps reduce the heart rate, which leads to a decrease in the oxygen demand of the heart muscle. The analogue Captopril Concor is indicated for the treatment of hypertension, coronary artery disease, accompanied by the presence of stable angina.
The initial dosage of the drug is 5 mg 1 time per day, taking into account the number of heartbeats and the general condition of the patient. According to indications, the dose of the drug can be increased to 10 mg per day.
Amlodipine
Manufacturer: KANOPHARMA PRODUCTION (Russia)
Release form: tablets
Active ingredient: amlodipine
Amlodipine has a relaxing effect on the smooth muscles of the vascular wall, which leads to a decrease in left ventricular hypertrophy. The drug prevents the formation of blood clots and is also used as a means of accelerating regenerative processes in the myocardium in coronary heart disease.
For the treatment of hypertension and the prevention of angina attacks against the background of coronary artery disease, the recommended initial dosage of the analogue is 5 mg once a day, which can be increased to 10 mg once a day according to indications.
Russian analogues of Kaptopress
For many reasons, some patients want to purchase high-quality analogues of the drug Kaptopres.
Among the most popular drugs that have a similar active ingredient are the following: Capozide, Capoten, Angiopril, Acetene, Capothiazide and Captopril.
Typically, analogues of any drug, in particular such as Captopres, are purchased in order to save money.
Indap is a medicine that allows you to reduce blood pressure in the shortest possible time. The pharmacological properties of the drug are similar to thiazide-like diuretics.
The drug Noliprel also quickly stabilizes blood pressure. The tablets contain two active ingredients - perindopril and indapamide.
