Spray to lower blood pressure

Few people know that not only medications in tablet form, but also sprays help against high blood pressure.

When using this or that spray as a medicine for blood pressure, you must consult a doctor.

Letters from our readers

Topic: Grandma's blood pressure has returned to normal!

From: Christina ( [email protected] )

To: Administration otgipertonii.ru

Christina, Moscow

My grandmother’s hypertension is hereditary - most likely, I will have the same problems as I get older.

I accidentally found an article on the Internet that literally saved my grandmother. She was tormented by headaches and had a repeated crisis. I bought the course and monitored the correct treatment.

After 6 weeks she even started talking differently. She said that her head no longer hurts, but she still takes pills for blood pressure. I am sending a link to the article

Compound

Pressure sprays have different compositions. The effectiveness of the drug depends on the components included in it.

Isoket spray

Production: Colep CC El Laupheim GmbH and Co.KG, Germany.

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The main substance is dinitrate isosobride, 1.25 mg in 1 dose. You can pay attention to the important substances in 1 can: macrogol 400 and 85% ethanol.

For ease of dosing of the spray to lower blood pressure, the package contains 15 ml of the drug, which corresponds to 300 presses. The patient can control the dose himself and change it on time.

Isosobride dinitrate in aerosol form is a fairly effective remedy in the treatment of coronary heart disease.

Nitrospray

, Russia.

The cylinder contains: nitroglycerin 4% - 250 g, ethanol -100 g.

It is less effective than nitromint spray, but is well used for patients with low-tension angina and unstable angina. It is well tolerated by patients.

Nitromint aerosol

. 1106, Budapest, st. Keresturi, 30-38, Hungary.

It contains: nitroglycerin 1% - 0.08 g, ethanol 96% - 7.92 g, propylene glycol - 2 g.

Surpasses nitrospray in the speed of onset and duration of the antianginal effect.

Indications for use of the aerosol

Among the indications for the use of aerosols against pressure surges are the following:

• Angina pectoris.
• Hypertension.
• Heart attack.
• Heart failure in the left ventricle.
• Thrombosis of the central retinal artery.

Indications for use are determined only by a doctor after examining the patient. Pressure sprays, especially intravenous ones, should be used to treat blood pressure only with the approval of a cardiologist. Such drugs are those medications, the improper use of which leads to adverse consequences.

Any drug has a number of contraindications that must be studied before using the drug. Anti-pressure sprays also have them.

Contraindications include:

• Intolerance to active components included in medications.
• If the lower pressure drops to 90 mm Hg. Art. and below.
• Pericarditis.
• Acute vascular insufficiency.
• Glaucoma.
• Liver and kidney failure.
• Acute myocardial infarction.
• The period of bearing a child and breastfeeding.

Contraindications for each pressure spray are different. They should be checked with your doctor before using them for treatment. Self-administration of medications during attacks of blood pressure contributes to the development of complications and deterioration of health in general.

If the patient has pathologies, then the use of these medications is possible only as a last resort. In addition, the use of drugs is not recommended during pregnancy, unless there is an indication for this. Also, many products are not used for children under 18 years of age (for example, Nitroglycerin).

The drug should not be used by people with glaucoma.

Tibetan herbal mixture is not used during pregnancy, allergies to its components, bradycardia and hypotension. The drug is not prescribed for pathologies such as:

• glaucoma;
• pericarditis;
• cardiogenic shock;
• liver and kidney failure;
• vascular insufficiency in the acute stage.

Under the supervision of a doctor, a drug is used to relieve attacks of myocardial infarction due to hypotension. Use with caution when there is a violation of cerebral circulation with stenosis, increased intracranial pressure. Animal studies show minimal risk to the fetus during pregnancy and breastfeeding.

Instructions for use

Shake the can before use and keep it vertical when spraying. It is most often applied sublingually to the mouth.

For preventive purposes, nitrospray is used once 5 minutes before exercise or a supposed stressful situation for the body. The maximum dose at a time is 4 injections. The maximum daily dosage is 4 times.

To relieve signs of angina pectoris, the drug is applied to or under the tongue, after holding your breath.

After spraying, you need to close your mouth; you do not need to swallow it right away. If necessary, then for the next administration of the drug you must wait half a minute, but no more than 3 doses within 15 minutes.

Release form

The drug is a clear, colorless solution with an alcoholic odor. It is available in two varieties:

1. Isoket spray is sublingual and dosed. With one click on the dispenser, one dose is released in the form of tiny drops, which consists of 1.25 mg of the active ingredient - isosorbide dinitrate, as well as auxiliary elements: ethanol and macrogol 400. The aerosol does not contain freon, therefore it is a harmless drug for the environment. Available in transparent 15 ml bottles, packed in a box with a dispenser and instructions. The glass bottle, designed for 300 clicks (doses), allows you to monitor the amount of the drug and promptly purchase a replacement.
2. A solution in the form of a concentrate intended for infusion. 1 ml of this drug contains 1 mg of the active element isosorbide dinitrate and additional substances: sodium chloride, sodium hydroxide, water. One ampoule contains 10 ml of solution for infusion. Available in cardboard packs of 10 pieces each.

Side effects

Impact on the central nervous system: rapid fatigue, blurred vision, cerebral ischemia, jet lag.

In the gastrointestinal tract: dry mouth, gagging and vomiting.

There may be a significant decrease in blood pressure, which develops into hypotension, headache, reaction slows down, spatial coordination is impaired, and a feeling of weakness.

Rashes and allergic reactions may occur on the skin: redness, itching, rash, hives. You may feel hot. Occasionally, Stevens-Johnson syndrome and angioedema appear.

Overdose

You should strictly adhere to the instructions prescribed by the doctor, as the consequences can be fatal.

An overdose of Isoket in the human body causes visual impairment, the skin is either pale or reddened, blood pressure drops quickly, bradycardia or tachycardia, increased work of the sweat glands, headaches, dizziness, and fainting.

Disturbances in the gastrointestinal tract, diarrhea, nausea, vomiting, increased pressure inside the skull, increased temperature, convulsions, paralysis and loss of consciousness up to coma.

When using and overdosing Nitrogel, weakness, fever, bluish lips, dizziness and fainting, shortness of breath, bradycardia or reflex tachycardia, fever, drowsiness, hypotension, vomiting, and diarrhea also appear.

After drinking alcohol, the risk of serious consequences is increased.

If doses are exceeded after coma, death inevitably occurs.

Interaction with other drugs

You cannot use the spray to lower blood pressure with vasodilators, antidepressants, chidine, novocainamide.

Arterial hypotension increases. Blood pressure can drop to such an extent that shock and then collapse occur.

A particularly strong effect is obtained when using a pressure-lowering spray in conjunction with sympathomimetics, alpha-blockers, beta-blockers, antipsychotics, and inhibitors.

Together with atropine, the possibility of intracranial pain increases due to a local increase in pressure.

pharmachologic effect

One of the effective pressure sprays is Nitroglycerin. It is often used to treat pathologies of the cardiovascular system. It is also prescribed for angina pectoris.

Penetrating into the body and combining with oxygen molecules, nitrogen reacts with it. As a result, nitric oxide is released. It helps the vascular walls begin to relax and the pressure returns to normal. This effect is exerted by guanylate cyclase, which is activated during exposure to nitric oxide.

After the level of this substance increases in the body, spasms are relieved, and the muscles of the stomach, bronchi, and ureters begin to relax. This effect on the body has a positive effect on a person during an attack of pressure surges. After the expansion of the venous vessels, the load on the heart quickly begins to decrease. The vasodilating effect of using Nitroglycerin helps relieve pain from the heart muscle.

The combined use of vasodilators and the drug “Izoket” (spray) is prohibited. Using them in combination may enhance the hypotensive effect. The same consequence entails the simultaneous use of Isoket aerosol and the following medications: antihypertensive drugs, calcium channel blockers, Quinidine or Novocainamide, antipsychotics, phosphodiesterase-5 inhibitors.

It is possible to enhance the antianginal effect when used in conjunction with drugs such as Amiodarone, Propranolol, Nifedipine, Verapamil, and other calcium channel blockers.

An increase in intracranial pressure in a patient may occur during combination therapy with atropine and other m-anticholinergics.

An excessive decrease in blood pressure, leading to coronary perfusion, occurs under the influence of alpha-blockers and sympathomimetics.

The instructions describe a lot of side effects that can be caused by the drug “Isoket” (spray). Reviews from some patients who took this medication indicate the appearance of headaches, which in medicine are called “nitrate headaches.” As a rule, after 2-3 days the problem disappears on its own and does not require correction. Quite rarely, the medication can cause symptoms such as nausea, redness of the skin, vomiting and dry mouth.

Some patients receiving the medication for the first time complain of general weakness, dizziness, decreased blood pressure and a feeling of lethargy. This is caused by minor disturbances in the functioning of the cardiovascular system. They occur during initial use or when the recommended dosage is exceeded.

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However, according to reviews, patients also noticed the effectiveness of the drug. And when taken in accordance with the instructions of a specialist, side effects do not occur so often. The exception is a headache in the first days of use, which accompanies most cases, but usually goes away within a few days.