The period of bearing a child is an exciting 9 months, during which many changes occur in a woman’s body. Some of them are associated with the appearance of a baby in a woman’s womb, others characterize pathological processes in the body of the expectant mother. Decreased immunity, worries and anxiety that affect a pregnant woman can provoke increased blood pressure and disturbances in the functioning of the cardiovascular system of the expectant mother. One of the drugs in the β-blocker group is Anaprilin. Is this drug safe to use during pregnancy? In what cases can Anaprilin be prescribed to a pregnant woman?
Is it advisable to use for the treatment of pregnant women?
Whether it is possible for a pregnant woman to take Anaprilin, only the gynecologist who is observing her can say for sure, because this drug has a strong effect. The use of propranolol, the active ingredient of Anaprilin, is advisable for the following indications:
- high blood pressure;
- angina pectoris;
- tachycardia;
- in the complex treatment of thyrotoxicosis;
- anxiety disorders;
- migraine.
Treatment during pregnancy is adjusted to minimize the risk to the health of the mother and developing fetus, taking into account the damaging effects of many medications, including anaprilin, on the child.
Contraindications of the drug
Anaprilin has a number of contraindications:
- Decreased ability of the heart to conduct.
- Bradycardia.
- Heart failure.
- Chronic hypotension.
- In cardiac pathologies, Anaprilin leads to pulmonary edema.
- Not recommended for asthmatics and diabetics, as there is a risk of hypoglycemic coma.
- Taking the medication is strictly prohibited if a person is engaged in work that requires high concentration, for example: driving a car.
Indications for prescribing anaprilin during pregnancy
Anaprilin can be prescribed to pregnant women with caution by the attending physician, since it belongs to the group of non-selective adrenergic blockers.
Such drugs inhibit the functioning of beta-adrenergic receptors located in the smooth muscles of internal organs and nerve fibers. These receptors respond to the release of adrenaline into the blood, which triggers processes in the body such as increased blood pressure and blood glucose levels, increased heart rate, relaxation of the smooth muscles of the bronchi and intestines, and feelings of anxiety, restlessness and tension.
Anaprilin blocks receptors that perceive adrenaline, thereby providing a hypotensive, calming effect, reducing heart rate and improving oxygen saturation of the heart muscle. These positive properties of the drug allow the doctor to prescribe it with great caution in the second half of pregnancy for diseases such as arterial hypertension, coronary artery disease, essential tremor, for the prevention of migraine attacks, panic attacks, and anxiety disorders.
Is Anaprilin harmless?
The drug is not absolutely safe. The main active ingredient is propranolol. Anaprilin is a beta-adrenergic blocking drug that stops the function of beta-adrenergic receptors. These receptors are located at the junctions of nerve fibers. Show excited reactions to the action of adrenaline.
Danger
Excitement itself causes an increase in the production of this hormone. A large amount of adrenaline in the blood can cause panic attacks. If fear occurs, accompanied by the release of adrenaline, a chain reaction is observed. Anaprilin reduces the sensitivity of adrenoreceptor cells to adrenaline, providing a blockade. It turns out that after experiencing or worrying, there is a lot of adrenaline in the blood, but it cannot have an effect on a person, since the drug closes the organs to him.
It is this effect of the drug that promotes calm and reduces panic attacks. However, Anaprilin is not a sedative or a psychotropic drug. If VSD develops, it needs to neutralize the effects of adrenaline in a short time.
Anaprilin is absorbed at high speed and begins to act five minutes after administration if dissolved in the mouth. The greatest effect is achieved an hour after using the drug. The action continues for five hours. The medicine is sold in tablet form.
Instructions for use for pregnant women
The dosage of the drug and the duration of treatment are determined by the attending physician, taking into account the severity of the disease, duration of pregnancy, etc. Tablets are available in dosages of 10 mg and 40 mg, taken orally after meals.
In early pregnancy
In the early gestational period, when the date is in the early stages of pregnancy, anaprilin is not used. No protective mechanisms have yet been formed in the “mother-child” system, and any substance, including propranolol, affects the embryo, the organs and systems of which are just being laid and formed. Such exposure is fraught with the appearance of various pathologies and developmental disorders in the fetus. It also blocks the functioning of beta-adrenergic receptors located in the muscles of the uterus, which can cause miscarriage - spontaneous termination of pregnancy.
In the later stages
In the later stages of pregnancy, the functional load on the mother's cardiovascular system increases, and the attending physician may prescribe Anaprilin to lower blood pressure, slow the pulse, treat angina pectoris, or select safer alternative drugs. Do not forget that a decrease in pressure and a decrease in vascular tone can negatively affect the child, causing hypoxia - oxygen starvation of the brain and tissues of the body. As a side effect, this can cause intrauterine growth retardation.
What does the medicine help with?
The drug belongs to the category of popular drugs for hypertension and vegetative-vascular dystonia. Anaprilin is often used for severe fears and panic attacks, since it has a low price, quickly helps relieve anxiety, reduce the pulse and reduce blood pressure.
Pressure measurement
The medication reduces the excitability of the heart muscle, the automatism of the sinus node, and the appearance of ectopic sources of excitability. The drug has a membrane-stabilizing effect, reduces the heart rate, inhibits atrioventricular conduction, reduces the load on the myocardium and the need for oxygen.
Anaprilin provides an antihypertensive effect - this effect becomes stable after the end of the second week of drug therapy. The activity of the angiotensin renin system decreases. The drug helps improve atherogenic blood quality.
When taking the drug, uterine contraction increases - it can be sudden or caused by drugs that are stimulants for the myometrium. This helps reduce the intensity of bleeding during labor and in the period after surgery.
Due to Anaprilin, the tone of the respiratory organs increases. And if you use the drug in large dosages, it provides a sedative effect.
Due to the fact that the production of aqueous medium in the eye chamber is inhibited, the drug can reduce intraocular pressure. And it does not affect the shape of the pupil.
Contraindications and side effects
Not only pregnancy is a contraindication for the use of Anaprilin. Conditions in which the use of the drug is strictly prohibited:
- cardiovascular system: acute myocardial infarction, sinus bradycardia, Prinzmetal's angina, right or left ventricular heart failure, weakness of the sinus node, low (less than 90 mm Hg) blood pressure;
- respiratory system: bronchial asthma, previous bronchospasms or a tendency to them;
- hay fever, hypersensitivity;
- diabetes mellitus with ketoacidosis;
- circulatory disorders in peripheral arteries;
- spastic colitis.
Great care in prescribing the drug requires bronchitis, diabetes mellitus (risk of a strong drop in blood glucose levels), hyperthyroidism, liver or kidney failure, depressive states, psoriasis, myasthenia gravis. Most doctors do not recommend the drug during breastfeeding.
Side effects of Anaprilin for mother and child in the womb have the following effect:
- decreased vascular tone of the placenta and fetus can cause oxygen starvation of the child’s tissues, which is extremely undesirable in the prenatal period;
- a drop in blood sugar can cause hypoglycemia, a condition that impairs the child’s nutrition and brain development;
- When using the drug, fetal bradycardia may develop - a small number of heartbeats per minute, which will lead to hypoxia in the child.
The noted contraindications and side effects of this drug show that in no case should it be used independently, not under the supervision of a doctor, especially when it comes to the health of the expectant mother and newborn.
Is it possible to take Anaprilin in the early and late stages of pregnancy?
Pregnancy is not only a period of joyful anticipation of the baby, but also a difficult time for the body.
All organs have to work under increased load, so various malfunctions often occur: chronic diseases worsen, the normal functioning of some systems is disrupted.
Treatment at this time is difficult, because many effective drugs cannot be used. Let's figure out whether Anaprilin can be used during pregnancy.
Cardiovascular diseases and disorders of the nervous system, accompanied by attacks of angina pectoris, panic attacks, tachycardia, and increased blood pressure, require systematic treatment.
One of the drugs prescribed in this case is Anaprilin. This drug helps to quickly normalize the condition. But can this remedy be used if a woman is pregnant? Will taking it affect the child's development?
Description
The product is available in the form of tablets, which contain:
- propranolol is the active ingredient;
- starch, lactose and other neutral fillers are used as auxiliary elements.
The active substance is a beta-adrenergic blocker, which belongs to the group of non-selective ones, that is, it does not act selectively, but immediately on all existing adrenergic receptors. The product has the following effect:
- normalizes heart rate;
- reduces blood pressure;
- helps improve the supply of oxygen to the myocardium, preventing the development of an attack of angina pectoris;
- increases bronchial tone;
- increases contractility of the uterus;
- reduces the risk of bleeding during the labor and postoperative period.
Advice! The active substance of the drug has the ability to penetrate the fetoplacental barrier.
Indications
Anaprilin is prescribed in the following cases:
- for cardiac arrhythmias - tachycardia, arrhythmia, etc.;
- for hypertension;
- during the treatment of thyrotoxicosis;
- with ischemic heart disease.
How to use?
The drug should never be taken without a doctor’s prescription, even if you are not pregnant. Basic recommendations:
- The drug should be taken approximately half an hour before the planned meal;
- The tablets can be swallowed without crushing and washed down with a small amount of water. With this method of administration, the effect will be noticeable two hours after administration;
- if a quick effect is needed, the tablet is placed under the tongue and dissolved. With this method of administration, the effect will occur within 20 minutes;
Advice! If you dissolve the tablet in your mouth, you will often experience a side effect such as numbness of the tongue.
- dosages are prescribed individually, depending on the disease and the severity of symptoms.
Is it advisable to use for the treatment of pregnant women?
After reading the description of the drug, we can conclude that taking Anaprilin during pregnancy is extremely undesirable. Firstly, this drug increases the contractility of the uterus, which can cause miscarriage. Therefore, taking it in the early stages is especially dangerous.
Secondly, the drug penetrates the placenta, which means that it can negatively affect the development of the baby. Thirdly, the drug affects blood vessels, including the blood vessels of the placenta, and this can cause fetal hypoxia, which is extremely undesirable at any time during pregnancy.
However, it is impossible to say that Anaprilin is never prescribed to pregnant women. The fact is that in some conditions treatment with this drug is necessary. For example, if a woman has high blood pressure, the risk of developing cerebrovascular accidents increases greatly. Therefore, it will not be possible to do without taking medications.
Advice! The active ingredients of the drug easily pass into breast milk. Therefore, if it is necessary to use the drug for the mother during lactation, breastfeeding must be stopped for the period of treatment.
Precautionary measures
As already mentioned, the drug is prescribed to pregnant women in exceptional cases. In addition, there are other contraindications for use. The drug must not be taken if:
- hypotension;
- asthma;
- vascular pathologies associated with their narrowing;
- some heart pathologies, namely with poor intracardiac conduction.
Side effects
If taken incorrectly or overdosed, various negative side effects develop. This:
- bradycardia;
- bronchospasms;
- convulsions;
- dizziness;
- digestive disorders.
special instructions
During treatment with Anaprilin, it is important to observe a number of conditions:
- prohibited from taking with antipsychotics and tranquilizers;
- with long-term therapy, additional intake of cardiac glucosides is necessary;
- discontinuation of the drug is carried out gradually, otherwise serious complications may develop;
- During treatment, exacerbation of psoriasis is often observed;
- the drug can affect the reaction rate and negatively affects vision, so it is advisable not to drive during treatment.
So, Anaprilin during pregnancy is prescribed only as an exception, when it is necessary to save the life and health of a woman. It is strictly forbidden to take the drug for self-medication, even if the woman has already taken it before. Treatment should be carried out under the supervision of medical professionals, since when taking the drug there is a risk of developing severe side effects.
Source: //jmiss.ru/zdorovie/beremennost/anaprilin-pri-beremennosti.html
