Due to the busy pace of life and lack of proper rest, most people experience regular nervous overload. Frequently occurring stress and negative factors lead to psycho-emotional disorders, dysfunction of many organs and systems, including the autonomic nervous system, which, due to the similarity of symptoms, were designated by one syndrome - vegetative-vascular dystonia. And dealing with them on your own is sometimes quite difficult. The drug "Mexidol" for VSD is designed to eliminate the manifestations of insomnia, migraines, heart failure and simply relieve prolonged depression.
Features of the treatment of vegetative-vascular dystonia
Treatment of VSD is complex and selected individually, depending on test results. However, some drugs, including Mexidol, can be prescribed for any form of this disease. When the blood supply to the brain is disrupted and nerve conduction deteriorates, the strength of cell walls decreases. Antioxidant drugs strengthen membranes and normalize blood circulation in the central nervous system.
Antioxidants are substances and medications that can influence lipid peroxidation reactions. These processes are dangerous for the body and occur with the participation of normal cells and free radicals - any substances that can affect metabolic reactions and destroy cell membranes. The human body has its own antioxidants, but if they are present in insufficient quantities, their supply must be replenished with special preparations.
REFERENCE! The action of antioxidants is not directed. They influence the processes of lipid peroxidation, which occur in any organ with the participation of specific and nonspecific cells.
The drug is most often prescribed in tablet form, but injections may be required to relieve acute attacks of VSD
Analogs
The beneficial effect of antioxidants on the body is possible during the use of Mexidol analogues, many of which are prescribed for the treatment of heart disease or dystonia.
The following drugs are similar in composition to Mexidol:
- Messifin;
- Cerecard;
- Mexico;
- Mexidant;
- Mexican;
- Neurox;
- Medomexy.
All these drugs are similar in their composition and effects on the body. They are produced both in the form of tablets and as a solution for injection.
Mexicor is often used to improve the condition of people suffering from alcohol intoxication. Regular use of the drug eliminates neurotic disorders that necessarily accompany a hangover. The active effect of the drug on brain activity reduces the manifestations of depression.
Mexifan is actively used to help people in stressful situations, in the presence of physical or mental exhaustion. This drug is used during the adaptation period after moving to other climatic zones or time zones.
In addition, Mexifan is used in newborns with central nervous system pathologies and elderly patients to level out the aging process of the body.
There are a number of drugs that differ from Mexidol in composition, but have a similar effect on the body. The most popular drugs are:
- Instenon is used in the presence of age-related changes in the functioning of the brain, headaches;
- Antifront, helps in normalizing blood pressure;
- Cortexin is used to treat head trauma, epilepsy, and cognitive disorders.
Composition and description of the drug
Mexidol is a complex action drug that is widely used for vegetative-vascular dystonia. The drug belongs to the groups of free radical oxidation inhibitors, membrane protectors, nootropics, antihypoxic and anti-stress drugs. It improves nutrition and blood supply to the brain, and also reduces the body's sensitivity to hypoxia. The main active ingredient of this medicine is ethylmethylhydroxypyridoxine succinate.
In the human body, Mexidol acts as follows:
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- enhances the activity of membrane enzymes, which leads to an increase in their strength and elasticity;
- increases the amount of dopamine in the brain - this leads to an acceleration of the processes of anaerobic glycolysis, which occur under conditions of hypoxia (insufficient oxygen supply) with the production of energy;
- improves the chemical properties of blood, which improves blood circulation in the central nervous system and prevents thrombosis;
- strengthens blood cell membranes;
- restores the functioning of the nervous system during periods of stress, normalizes sleep and prevents dystrophy of certain areas of the brain;
- promotes the elimination of toxins and metabolic products of certain medications;
- normalizes cardiac activity during ischemia.
All such effects affect the patient's condition. As a result of taking the drug, the functioning of the central nervous system and myocardium improves, blood vessels are strengthened and the composition of the blood improves. Thus, all cells of the body receive a sufficient amount of oxygen and nutrients, which produces energy for their normal functioning. The risk of blood clots, the main cause of myocardial infarction, is also reduced. The effect of Mexidol is especially noticeable under conditions of hypoxia, that is, when the supply of oxygen to individual organs and tissues is disrupted.
Who is the drug suitable for?
Mexidol is a complex action drug that helps improve cerebral blood supply, increase mental and physical performance, as well as stabilize the psycho-emotional background. So, after a course of taking the drug, the following positive changes are noted:
- strengthening and protecting brain cells from destruction;
- normalization of cerebral blood supply;
- smoothing of neurotic manifestations or their complete elimination;
- reducing anxiety, eliminating irritability, nervousness, headaches;
- improving the functioning of the heart and blood vessels;
- restoration of energy and performance;
- removal of toxins;
- increased dopamine production;
- improved sleep.
Knowing about the changes that Mexidol can contribute to, we can conclude that this remedy will be an excellent assistant for patients with PA. It is known that “alarmists,” in addition to constant anxiety, are often bothered by symptoms such as insomnia, loss of energy, low mood, and severe irritability. In addition, the advantages of using the drug Mexidol for a panic attack include the fact that this drug promotes calm and relaxation.
Indications for use
Since Mexidol has a complex effect on the human body, it is prescribed for many different pathologies. Most often, indications for its use are disorders of the brain and cardiovascular system. Phenomena in which this drug has a positive therapeutic effect include:
- acute cerebrovascular accidents and their consequences, including after attacks of ischemia;
- traumatic brain injuries and the rehabilitation period after them;
- encephalopathy of any origin;
- disorders of the nervous system associated with atherosclerosis;
- vegetative-vascular dystonia;
- anxiety states and sleep disorders caused by neuroses;
- withdrawal syndrome in chronic alcoholism;
- relief of conditions after acute intoxication with medications (usually antipsychotic drugs), various neurotropic poisons;
- stressful situations that manifest themselves as disturbances in the functioning of the autonomic nervous system.
IMPORTANT! Despite the fact that Mexidol has a positive effect on the human body, it should be taken only when indicated. Like any other medicine, it has contraindications and can cause side effects.
The main symptoms of VSD are headaches and dizziness, but it can have individual manifestations in different people.
Overdose and compatibility
High levels of the active component of Mexidol in the blood, due to the use of the drug in high doses, can cause drowsiness. The pharmaceutical drug is compatible with all medications intended for the treatment of somatic pathologies. When taking Mexidol together with antidepressants, tranquilizers, anticonvulsants and antipsychotic medications, their pharmacological effect on the body increases.
It is possible to reduce the toxicity of ethanol when used together with Mexidol. The drug is compatible with alcohol and eliminates the symptoms of alcohol intoxication, but it saves cells from destruction by ethyl. To increase the mental abilities of children, it is recommended to combine Mexidol with the drug Nootropil. This combination of medications is effective for patients who have suffered an ischemic stroke or coma.
Source: etodavlenie.ru
The mechanism of action of the drug in VSD
Vegetative-vascular dystonia can manifest itself constantly or episodically. During these periods, the patient complains of general weakness and malaise, headaches and dizziness, fever, insomnia, a feeling of lack of air or panic attacks. Other manifestations of VSD include trembling and numbness of the limbs, as well as coldness. All these signs are associated with insufficient oxygen supply to the brain, which affects the innervation of the limbs and internal organs.
Mexidol has a number of positive effects for VSD:
- strengthens brain cells and prevents their destruction;
- normalizes blood flow in the central nervous system and distal limbs;
- has a calming effect and relieves signs of neuroses;
- activates energy production processes for normal brain function under hypoxic conditions;
- relieves headaches, restores strength and performance.
There is a classification that identifies several types of vegetative-vascular dystonia. Mexidol will be effective for each of them. Since it acts at the cellular level and affects the mechanism of disease development, after a course of taking it it is possible to stop all possible causes of VSD. The effectiveness of the drug depends on the severity of clinical signs, cause and severity of the disease.
conclusions
VSD is a neurogenic multifactorial disease that adversely affects the quality of daily life. Patients complain of decreased ability to work, decreased alertness, and the appearance of chronic fatigue. Since there is no organic substrate for pathology, doctors use symptomatic remedies, as well as antioxidants and metabolic agents, which do not have an evidence base. A prominent representative of such drugs is Mexidol, a new generation drug widely used to treat patients with vegetative-vascular dystonia.
The following sources of information were used to prepare the material.
Source: cardiograf.com
Instructions and dosages
Mexidol is produced in two main forms: tablets and solution for injection. The tablets contain 125 mg of active ingredient and are sold in packages with contour cells of 10 pieces. The solution is contained in ampoules of 5 ml, each containing 50 mg of the active substance. The duration of treatment with this drug and dosage are selected individually, depending on the cause and severity of the disease. Details about the form and dose in which the medicine should be taken can be found in the table, but only the attending physician can provide accurate information.
| Diagnosis | Mexidol form | Dosage per day | Course duration |
| Treatment of mild traumatic brain injuries and their consequences | Pills | Up to 800 mg, 125-250 mg per dose | From several days to several months |
| Poor circulation in the brain | Injections at the end of the course can be replaced with tablets | In the first 3 days - 300 ml drip, then 100 per day intramuscularly | Up to 2 weeks |
| Withdrawal syndrome | Pills | 250 mg (2 tablets) 2 times a day | No more than 1 week |
| Encephalopathies | Injections | Up to 500 ml, divided into 2 procedures, administered intravenously | Up to 2 weeks |
| Intoxication | Injections | Up to 500 ml per day intravenously, divide the dose into 2 doses | 1-2 weeks |
The tablets should be taken after meals and washed down with water. The daily dose should be divided into 2-3 doses. The drug is indicated for the relief of acute attacks of VSD and is prescribed according to indications. However, it can also be taken to prevent another relapse if the patient’s relapse is related to weather conditions. Most often they occur in spring and autumn.
REFERENCE! Mexidol for VSD is often used in tablet form. However, during acute attacks of the disease, if they are associated with organic brain damage and impaired brain activity, a course of injections may be required.
The active ingredients of the drug restore cell walls and normalize blood circulation in the brain
Release form
Mexidol is available in two forms: tablets and ampoules for injection. Tablets are preferred by most patients, although doctors more often prescribe injections for VSD.
Mexidol tablets have the most common appearance - a round white shape - and contain 125 mg of the active substance (ethylmethylhydroxypyridine succinate). It also contains lactose monohydrate, which allergy sufferers should pay attention to.
The ampoules are transparent vessels with three stripes on the top. They contain 2 ml of a 5% solution of the active substance, as well as water for injection and the excipient sodium metabisulfite.
Contraindications and possible side effects
Mexidol has low toxicity and is well tolerated by patients. However, like any other medicine, it can cause allergic reactions. More often they are manifested by swelling of the mucous membranes, rash and other mild symptoms. Some patients may also experience nausea, headaches, surges in blood pressure, insomnia and nervousness.
The drug also has a number of contraindications for use. These include:
- chronic renal or liver failure;
- children under 12 years of age;
- periods of pregnancy and lactation;
- hypersensitivity to the components of the drug.
Mexidol is prescribed with caution for chronic high or low blood pressure. These phenomena are not contraindications, but require medical supervision. Some specialists also use the drug for children under 12 years of age if the risks to the patient's health outweigh the risk of possible side effects.
Mexidol is an effective remedy for restoring the functioning of the nervous and cardiovascular systems. It is also prescribed for vegetative-vascular dystonia to relieve acute attacks and to prevent relapses. The drug is well tolerated and rarely causes side effects.
How to drink Mexidol when treating blood pressure?
It is recommended to use Mexidol during meals. The dosage and duration of the treatment course is determined by a specialized physician after examining the patient and studying the clinical picture of the disease. Usually start taking the medicine with 1-2 tablets, gradually increasing the dosage until a therapeutic effect is achieved. You should not take more than 6 tablets per day. The duration of treatment is 14-45 days and at the end of the course the dosage is gradually reduced. If the doctor’s recommendations are ignored, the risk of developing side symptoms increases significantly, so it is extremely important during the treatment process to strictly follow the instructions and the treatment regimen prescribed by the doctor. Using the Mexidol solution, injections are made by injecting the medicinal liquid dropwise or in a stream. The maximum daily dose of the solution should not exceed 1.2 g.
Reviews about the product
Elena, 32 years old I was diagnosed with VSD as a teenager, and I would like to leave a review about the drug Mexidol. The doctor prescribed it to me in tablets, I took 2 tablets a day for 2 weeks. During this time, improvements became clearly visible. Headaches disappeared, strength for work and rest appeared, sleep was restored. The treatment will have to be repeated periodically, of course, but I am satisfied with the result.
Igor, 36 years old I began to experience symptoms of VSD after a traumatic brain injury. There were sudden dizziness to the point of loss of consciousness, constant migraines. This did not happen constantly, but in attacks, that is, basically these signs were absent. Once again I went for an examination and was prescribed Mexidol. Instead of having headaches for a week at a time, as was the case before, I can now get rid of them in a couple of days. Good product, I recommend it.
Side effects
With low blood pressure, Mexidol often increases levels, which may cause signs of hypertension. The patient may experience increased blood pressure and other negative reactions:
Epigastric pain may be a side effect of the drug.
- attacks of nausea causing vomiting;
- constant desire to sleep;
- allergic reaction;
- pain in the epigastrium;
- drying of the oral mucosa;
- burning sensations in the digestive tract;
- constant belching;
- lethargic state;
- broken stools with regular constipation or diarrhea;
- flatulence.
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Using the solution
The use of this component in ampoules is practiced in case of severe vascular dystonia. One ampoule of the medicine contains a five percent medicinal solution with a volume of 2 milliliters.
It is acceptable to use the drug intravenously and intramuscularly. The method of administering the injection is determined by the doctor, based on the individual characteristics of the patient. Most often, patients are prescribed intramuscular injections. In extremely severe situations of the disease, droppers with the drug are used.
Mexidol injections for VSD are given three times. During treatment, you should try to stick to the same time of taking the drug. The course of injection treatment for dystonia lasts, as a rule, for ten days. After completing this course, patients are prescribed further therapy in tablet form.
How does it fit together?
For people who take Mexidol together with alcoholic drinks, the state of intoxication occurs much later. This is due to minimizing the effect of alcohol on the patient’s body. Active substances contribute to the rapid removal of toxic substances from the body. But still, you should not combine alcohol and medicine to avoid unwanted consequences. Combine Mexidol with caution with the following groups of drugs:
- antidepressants;
- anxiolytic substances;
- medications to prevent seizures;
- pharmaceuticals containing benzodiazepines;
- medications against symptoms of Parkinson's disease.
Combining Mexidol with Nootropil in childhood helps improve mental abilities.
