Dibazol is a complex action drug. It has a hypotensive and antispasmodic effect on the body. The use of the medication is safe for children over 12 years of age with diabetes. It is recommended to consult your doctor before starting therapy that includes the drug. If side effects occur, the medicine should be changed. Self-medication can be harmful to health and cause complications for the patient.
Dibazol – consultation with a doctor
Release form and composition
The drug is produced in the form of tablets, in ampoules for the preparation of injections. The active ingredient is bendazole. An ampoule of solution for injection consists of an active substance in a volume of 5 to 10 mg per 1 ml. The tablet consists of 20 mg bendazole. For treatment in pediatrics, the drug is available in the form of tablets containing the active ingredient in the range of 2 mg, 3 mg, 4 mg. Release form:
- injection solution – 5 mg ampoules (0.5%, 1% bendazole) in the amount of 10 pieces in a blister;
- tablets - for adults (20 mg bendazole) 10 pieces in a blister, two, four per package, for children (2 mg, 3 mg, 4 mg bendazole) 10 pieces in a blister, three, four per package.
In addition to the active component, the drug contains auxiliary ingredients. Additional substances included in the medicine:
- Purified microtalc is a white crystalline substance with a fatty structure. The ingredient does not cause allergies. Used to fill the bulk of the tablet in combination with the active substance.
- Milk sugar (lactose) – provides taste, replaces sugar.
- Potato starch – fills the volume, does not act as a dangerous component (hypoallergenic).
- Calcium stearate is an emulsifier. Responsible for uniform mixing of components.
- Polyvinylpyrrolidone is a synthetic polymer that is soluble in water. Characterized as a food additive. Thickener components, gives light color.
Auxiliary ingredients that make up the injection solution:
- hydrogen chloride – increases the absorption rate of iron, ensures acceleration of the absorption of useful components;
- liquid for preparing an injection solution.
Use of Dibazol for blood pressure
Instructions
In case of hypertensive crisis, the injection solution is administered intramuscularly or intravenously at 30 or 40 mg.
The course of therapy can be repeated after a month if necessary. It is possible to use the medicine to prevent high blood pressure until the patient’s condition returns to normal and the pressure decreases.
When administered intravenously, two to three milliliters of a one percent drug are required once a day or four to six milliliters of a 0.5 percent drug three times a day. Typically, the duration of treatment is from one to two weeks, depending on the nature of the pathology, as well as the individual characteristics of the patient.
There are some features of drug administration:
- To administer the drug intramuscularly, the solution is diluted with injection water.
- If intravenous administration is necessary, Dibazol is diluted in a 0.9% solution of Sodium Chloride. It is recommended to administer slowly.
Women may be prescribed medication during pregnancy if the benefit to the mother outweighs the potential risk to the fetus.
However, in the first trimester, when the formation of the baby’s organs occurs, it is undesirable to use the drug.
To treat lactation women with Dibazol, breastfeeding should be stopped.
You can purchase the medicine at any pharmaceutical establishment. The approximate cost of the solution for injection is from 100 Russian rubles. One ampoule costs between 10-30 rubles.
Reviews from specialists and patients about the drug are mostly positive.
Maria Ignatievna, 45 years old
“I get Dibazol injections for a hypertensive crisis. I want to say that the drug is effective and quickly helps reduce blood pressure. I have not observed any adverse reactions from its use. My grandson was prescribed the medicine in tablets for colic.”
Alexander Stanislavovich, 40 years old
“Dibazol injections are often prescribed for exacerbation of hypertension. Now, during a crisis, my daughter gives injections at home. The remedy, although outdated (after all, at this time there are many other modern drugs for lowering blood pressure), is very effective. Moreover, it is inexpensive compared to other medications.”
https://www.youtube.com/watch?v=ZNrHA47X2k4
Ekaterina Valerievna, 39 years old
“We were prescribed Dibazol injections after I was admitted to the hospital with high blood pressure. I heard a lot of good reviews about the drug. But I personally won’t say that the medicine is really very effective. Perhaps a more expected result is obtained if it is used in complex treatment. In addition, I had side effects from using Dibazol - nausea and dizziness. Therefore, I asked the attending doctor to prescribe me another drug.”
Galina Nikolaevna, 50 years old
“I am constantly prescribed Dibazol for high blood pressure. The drug is effective and helps quickly. However, long-term effectiveness from the use of injections has not been observed. Among the advantages are low cost, rapid therapeutic effect, availability, and a minimal list of contraindications for use.
Thus, Dibazol injections are often used to treat exacerbations of hypertension. It is important to remember that only an experienced specialist can prescribe the drug. Self-medication can aggravate the situation and worsen the patient’s well-being.
Latin name: Dibazol / Dibazolum.
INN (international nonproprietary name): Bendazole / Bendazolum.
Group of drugs: Dibazol belongs to myotropic antispasmodics.
Release forms
1. Tablets 2; 3; 4 mg for children and 20 mg N10 for adults.
2. Ampoules of 0.5% and 1% solution, 1 each; 2 and 5 ml for parenteral administration.
Composition of Dibazol
Active ingredient: bendazole (2-Benzylbenzimidazole hydrochloride)
Auxiliary components: talc, lactose, potato starch, calcium stearate, polyvinylpyrrolidone.
White crystalline powder with a grayish or yellowish tint, bitter-salty taste. Difficult to dissolve in water, quite easily soluble in alcohol. Hygroscopic.
It has myotropic (effect on muscles), antispasmodic, vasodilator and moderate, short-term hypotensive (pressure-reducing) effect. It affects the smooth muscles of blood vessels (arterioles and venules) and the vessels of internal organs. By reducing the tone of blood vessels, Dibazol thereby reduces blood pressure and increases blood supply to areas of myocardial ischemia, which is observed in coronary heart disease. It is capable of stimulating interneuron transmission at spinal cord synapses, which has found wide application in neurology.
Dibazole also has moderate immunomodulatory activity, as it is similar to levamisole, which is a drug that stimulates immune processes. The immunostimulating effect of Dibazol is due to the ability to enhance the production of endogenous interferon.
- Early stage of arterial hypertension.
- Hypertensive crisis .
- Diseases of internal organs accompanied by spasms of smooth muscles (stomach and duodenal ulcers, spasms of the pylorus and intestines, hepatic and renal colic, etc.).
- Neurological diseases, especially residual symptoms of polio in children, consequences of birth injuries. paralysis of the facial nerve and other diseases of the nervous system in the recovery stage.
- As a mild immunostimulating agent (in combination with ascorbic acid and Thymogen, Dibazol is effective in the fight against influenza and other cold viral infections).
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Contraindications
1. Individual intolerance to the drug.
2. Arterial hypotension and tendency to low blood pressure.
The drug is prescribed parenterally (into a vein, into a muscle), and orally.
It is possible to administer Dibazol by electrophoresis for neurological diseases.
For arterial hypertension (blood pressure significantly higher than 140/90 mmHg), Dibazol is prescribed intramuscularly, 1% solution 2-3 ml or 0.5% solution 4-6 ml, which corresponds to a drug dosage of 20-30 mg. The duration of treatment is 8-14 days.
Together with Dibazol, it is possible to use other antihypertensive drugs.
For the treatment of arterial hypertension, Dibazol is prescribed in tablet form: 20-50 mg orally 2-3 times a day, between meals, for an average duration of 2-4 weeks.
In order to relieve a hypertensive crisis, the drug is administered into a vein or into a muscle at a dosage of 30-40 mg, i.e. 1% solution 3-4 ml or 0.5% solution 6-8 ml.
In neurological practice, Dibazol is prescribed to adults at a dose of 5 mg once a day for 10 days.
For children, the dosage is selected depending on age. Up to 1 year (newborns and infants) – 1 mg. For children from one to 12 years of age, the dosage ranges from 2 to 5 mg, and is selected individually for each child. After 21-28 days, the course of treatment must be repeated. Each subsequent course is carried out every 1-2 months.
Maximum doses for adults for oral administration: single – 0.05 g, daily – 0.15 g.
For a cold viral infection, Dibazol is prescribed in an individually selected dosage intravenously, in combination with ascorbic acid or calcium gluconate.
Dibazol is classified as an adaptogen – substances that increase the body’s resistance to various external influences. Under the influence of small doses of this drug, the production of interferons is stimulated and the level of endorphins increases. interleukins, natural killer cells and phagocytes (all of which are active components of the immune defense).
To prevent the occurrence of influenza and other viral infections, Dibazol must be taken for a long time (at least a month), 0.01 g per day.
In addition to stimulating cellular immunity, Dibazol also affects the body's stability through its effect on the nervous system, maintaining the constancy of all basic physiological processes.
Side effects
Allergic reactions: pinpoint rash may appear. itchy skin. In rare cases, the use of Dibazol may be accompanied by headache.
Overdose
There is no specific antidote. In case of an overdose of Dibazol tablets, gastric lavage is possible. taking saline laxatives.
If the first symptoms of an overdose occur, you must stop taking Dibazol and consult your doctor about the advisability of continuing to take the drug.
Dibazol: instructions for use, at what pressure is it indicated?
It is recommended to use the drug as prescribed by a doctor. Self-medication can lead to side effects, complications, and deterioration of well-being. Medicine is prescribed if there is a diagnosis:
- high blood pressure (BP), occurring periodically or constantly;
- hypertensive crisis;
- muscle spasm;
- remaining signs of poliomyelitis;
- nervous disorders leading to sensory impairment.
In medical practice, the medication is not used during a woman’s pregnancy and lactation. For treatment purposes, select another antihypertensive medication.
Side effects
In most cases, taking Dibazol does not cause complications. But the annotation indicates cases of the development of some side effects of the drug. Not every hypertensive patient will benefit from medication properly, and sometimes it can even cause harm. To prevent dangerous complications, you need to know about the side effects of the drug. These include:
- prolonged attacks of headache;
- nausea with vomiting;
- dizziness;
- profuse sweating;
- hypersensitivity reactions.
If a woman is pregnant, she may develop a spasm of smooth muscles, which requires urgent intensive therapy; Dibazol is often prescribed. It is allowed during pregnancy, as it has minimal effect on the unborn child.
Side effects
The annotation states that such therapy should be carried out only under the close supervision of a specialist, so that the patient cannot increase the dose or increase the duration of treatment.
“Dibazol” does not harm your health during pregnancy, but it is important not to forget about its interaction with other medications. The combination of “Dibazol” with “Papaverine” is often used to normalize the well-being of a pregnant woman with high blood pressure. This will not harm the fetus at all, but will quickly stabilize the condition.
Dynamics of the drug's effect
Dibazole for blood pressure is a medication that affects the vascular walls. The vasodilating effect ensures a decrease in blood pressure. The pharmacological action of the drug is characterized by:
- expansion of the lumens of blood vessels;
- stimulating the spinal cord;
- decrease in blood pressure;
- antispasmodic effect on muscles.
Dibazol, at what pressure should it be taken? The medicine has an immunostimulating effect and dilates blood vessels in the brain. Prescribed for a sharp increase in blood pressure. The active substance is absorbed through the gastrointestinal tract when taken orally. The drug effect is achieved 40-50 minutes after administration. The action is designed for a period of 2.5 to 3.5 hours. After the injection, a decrease in blood pressure is observed after 18 minutes.
Combination drugs with Dibazol
In medicine, combination drugs are widely used, which include Dibazol:
- "Papazole" based on papaverine and dibazole, 30 mg. Prescribed for vascular spasms, slight excess of normal blood pressure limits.
- "Theodibaverine" contains dibazole 20 mg, papaverine 20 mg and theobromine 15 mg. Prescribed for cerebral vascular spasms.
- "Andipal" is produced on the basis of phenobarbital 20 mg, dibazol 20 mg and analgin 25 mg. The medication dilates blood vessels, eliminates smooth muscle spasms and reduces pain.
All drugs are characterized by the same mechanism of action on the body, relieve spasms, dilate blood vessels and safely lower blood pressure.
How to take Dibazol for blood pressure?
To determine the dosage during medication therapy, it is recommended to consult your doctor. The use of Dibazol for blood pressure differs depending on the form of release and purpose of administration. Injections are given intramuscularly and intravenously. The dosage is calculated depending on:
- patient diagnosis;
- age;
- well-being.
Patients over the age of 18 years are prescribed intramuscular injections in the following volumes:
- During a hypertensive crisis - 3-5 ml.
- For high blood pressure – 2-3 ml 3 times every 24 hours. The course of therapy ranges from 10 to 14 days.
Dibazol tablets for blood pressure dosage:
- Patients over 12 years old - from 30-50 mg three times every 24 hours.
- The maximum daily dosage of Dibazol tablets should not exceed 150 mg per day.
- It is forbidden to consume more than 50 mg at one time.
The medicine is prescribed for disorders of the nervous system in a volume of up to 5 mg once every 24 hours. For smooth muscle spasms, take the medication at a dose of 5 mg at a time. To achieve an antispasmodic effect, the number of times of administration is up to 8.
How to give Dibazol to children
Dibazol price, where to buy Dibazol tablets
The price of the medicine is relatively low. The average cost of the tablet form in Russia is from 30 rubles. The solution costs a little more - about 40 rubles.
- Online pharmacies in RussiaRussia
- Online pharmacies in UkraineUkraine
ZdravCity
- Dibazol solution for intravenous and intramuscular administration.
1% 5ml 10 pcs. JSC Dalkhimfarm 41 rub. order - Dibazol-UBF tablets 20 mg 10 pcs. JSC Uralbiopharm
42 RUR order
- Dibazol solution for intravenous and intramuscular administration. 1% 1ml 10 pcs. JSC Dalkhimfarm
28 RUR order
Pharmacy Dialogue
- Dibazol (20 mg tablet No. 10) MFF
51 RUR order
- Dibazol-UBF (20 mg tablet No. 10) Uralbiopharm
51 RUR order
- Dibazol (amp. 1% 5ml No. 10) DHF JSC
47 RUR order
- Dibazol (amp. 1% 1ml No. 10) DHF JSC
35 rub. order
show more
Pharmacy24
- Dibazol-Darnitsa 0.02 No. 10 tablets PrAT" Pharmaceutical company "Darnitsa", Ukraine
8 UAH. order - Dibazol-Darnitsa 1% 5 ml No. 10 injection solution PrAT” Pharmaceutical company “Darnitsa”, Ukraine
51 UAH order
- Dibazol-Darnitsa 1% 1 ml No. 10 injection solution PrAT" Pharmaceutical company "Darnitsa", Ukraine
21 UAH order
- Analgin-dibazole-papaverine No. 10 tablets INTERCHEM Partnership with additional coverage, Ukraine
19 UAH order
Contraindications
Dibazol for blood pressure has a number of contraindications. It is prohibited to carry out therapy with the drug if:
- hypersensitivity, individual intolerance to individual components that make up the drug;
- disorders of the renal system;
- gastrointestinal ulcers accompanied by bleeding;
- hyperglycemia;
- involuntary muscle contraction caused by irritation of neurons;
- heart failure;
- decreased muscle tone:
- age up to 12 years.
When driving vehicles or operating machinery, the drug should be prescribed with caution. May cause dizziness.
Dizziness and nausea from Dibazol
Use of medication in childhood
In exceptional cases, medicine containing bendazole is prescribed to children, even infants. Under no circumstances should you self-medicate. Such therapy is carried out under the supervision of a doctor in order to eliminate the consequences of a difficult birth. This could be increased muscle tone, a baby’s sleep disorder, extremely critical indicators of intracranial pressure, or chin tremor.
The drug is usually prescribed to young patients in injections. The proportions indicated in the instructions and recommended by a specialist must be strictly observed, and the age characteristics of children must be taken into account. For therapeutic purposes, it is permitted to use the drug substance in the form of a powder, which is prepared for oral administration as follows. The active substance bendazole (0.001 g) is mixed with glucose (0.3 g) and a small amount of water.
Side effects on the body
The medication is well tolerated. Side effects are rare. They appear as a result of self-medication, incorrect dosage, lack of preliminary examination, or consultation with a doctor. A negative reaction of the body to Dibazol manifests itself in the form of:
- rashes on the skin;
- facial redness;
- a sharp drop in blood pressure;
- sensations of itching, burning in the injection area;
- headache, dizziness;
- pain in the abdominal area;
- nausea, vomiting.
Clinical studies have shown that the drug has an effect on ECG readings. It is not recommended to prescribe to elderly patients.
special instructions
During treatment, it is recommended to refrain from driving any vehicles, as there is a high risk of developing dizziness.
Since Dibazol can affect ECG parameters, the drug is not prescribed to elderly patients.
During pregnancy, Dibazol can be prescribed in case of increased blood pressure due to gestosis or another disease, for example, hyperthyroidism. The drug is not suitable for daily use; its use is indicated only in emergency cases.
The simultaneous use of Dibazol with drugs such as Clonidine, Reserpine, Phentolamine is not recommended due to a sharp drop in blood pressure.
The use of Dibazol with Papaverine is effective. These medications complement and enhance each other's effects. The condition improves after 10-15 minutes.
Overdose
If the dosage of the medication is incorrect, the patient may experience symptoms of overdose. Study in detail the instructions for using Dibazol for blood pressure. The main forms of manifestation of an excess of the active component in the body:
- increased body temperature;
- headache;
- increased sweating;
- nausea.
First aid for a patient in case of overdose:
- avoid taking medication;
- rinse the stomach;
- lay in a horizontal position;
- ensure free access of air;
- call a doctor.
Self-medication with the drug is prohibited. The dosage should be calculated by the attending physician. He will advise on the advisability of therapy using the drug based on the patient’s general condition and the body’s individual reaction to the components of Dibazol.
Alternative to Dibazol
Indications for use
There are still people who do not know whether Dibazol increases or decreases blood pressure.
The instructions for use that accompany Dibazol clearly indicate at what pressure to use it - at high pressure.
Dibazole is used in the treatment of patients with spasms of the smooth muscle layers of blood vessels. Dibazol is effective for hypertensive crisis.
Often the medicine is used to avoid smooth muscle spasms in people who have stomach ulcers or often experience intestinal colic. In addition, the drug is prescribed for problems with the nervous system.
Analogs
In modern medicine, both the original drug and its analogues are used. In the absence of a medicine, there are a number of drugs that have the same purpose and mechanism of action on the body. The most popular analogues among patients are:
- Duzopharm;
- Enelbin;
- Papazol;
- Dibenzimil;
- Vinoxin;
- Halidor;
- Bendazole.
Various auxiliary components and properties help to choose the safest drug for the patient. Therapy should be especially carefully prescribed during pregnancy and lactation. Before starting treatment, read the instructions. Remember, therapy and dosage must be prescribed by the attending physician. Self-medication can provoke negative effects on the body and side effects.
Video on the topic
Magnesia, Dibazol, Papaverine are the most popular injections for high blood pressure. What other drugs are used for injections for hypertension can be found in this video:
Dibazol is an effective remedy for combating smooth muscle spasms, hypertension, as well as problems of the nervous system. Thanks to several forms of release of the drug, it is convenient to take it for both adults and children. The medicine has virtually no side effects or contraindications. However, Dibazol is available by prescription, so before going to the pharmacy you should definitely consult a specialist.
The information on the MyMedNews.ru website is for reference and general information, collected from publicly available sources and cannot serve as a basis for making a decision on the use of medications in the course of treatment.
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Children, pregnancy and breastfeeding
It is possible to prescribe Dibazol during pregnancy if the expected benefit outweighs the potential risk to the fetus. When taking the drug, it is recommended to interrupt breastfeeding.
For older children, tablets with a dosage of 4 mg are produced; for infants, solutions are prepared at specialized points in pharmacies.
For older children, tablets with a dosage of 4 mg are produced; for infants, solutions are prepared at specialized points in pharmacies. In pediatric practice, the medication is prescribed for the following conditions:
- colic and spasms. The medication has a gentle effect on smooth muscles, relieving babies of pain caused by spasms of the smooth muscle tissue of internal organs;
- muscle hypotonia that developed after a difficult birth, as a result of prolonged hypoxia, hereditary pathology of the neuromuscular system, with various chromosomal syndromes;
- influenza, ARVI, colds. The medication enhances the production of interferon when the virus enters the child’s body;
- stress and fatigue. Dibazol is characterized by an adaptogenic effect, which makes it possible to increase the nonspecific resistance of the child’s body.
Should be used with caution in elderly patients. It is not recommended to use Dibazol for blood pressure for a long time (for the treatment of arterial hypertension), especially in elderly patients
When treating with Dibazol, caution should be exercised when driving vehicles and performing work that requires increased concentration and immediate psychomotor reactions, due to the risk of developing headaches and dizziness. An increase in the severity of the antihypertensive effect has been recorded when used simultaneously with diuretic medications and antihypertensive drugs.
Bendazole is able to prevent an increase in peripheral vascular resistance caused by taking beta-blockers. The hypotensive effect of Dibazol is enhanced when taking Phentolamine
An increase in the severity of the antihypertensive effect has been recorded when used simultaneously with diuretic medications and antihypertensive drugs. Bendazole is able to prevent an increase in peripheral vascular resistance caused by taking beta-blockers. The hypotensive effect of Dibazol is enhanced when taking Phentolamine.
- Bendazole.
- Dibazol Vial; Darnitsa; UBF.
- Dibazole solution for injection 1%.
The average cost of Dibazol (20 mg tablets No. 10) in Moscow is 17 rubles. The price of injections is 25 rubles for 10 ampoules. Dispensed by prescription.
Keep out of the reach of children. Best before date:
- Tablets: 5 years at room temperature (not higher than 25 C).
- Solution for injection: 4 years at a temperature of 5-30 C.
