Original bisoprolol and generics. Is it possible to blindly trust generic drugs?

Nowadays, many people have problems with the cardiovascular system. They are accompanied by unstable, spasmodic blood pressure, so the search for the optimal treatment remains an urgent task.

Bisoprolol is one of the effective options for solving the problem of blood pressure. However, before use, you should carefully study all aspects of taking this serious drug.

pharmachologic effect

Bisoprolol is a selective beta 1-blocker with no membrane stabilizing activity. In blood plasma, it effectively reduces renin activity, helps reduce myocardial oxygen consumption, and has an antianginal and hypotensive effect. Without changing stroke volume, it helps reduce heart rate during exercise and optimizes cardiac output.

The maximum therapeutic effect occurs after taking Bisoprolol quite quickly and lasts about a day. The active substance can be adsorbed by 90% regardless of food intake. Metabolism occurs in the liver. 98% of the drug is excreted in urine.

Application

For children

The use of Bisoprolol in childhood or adolescence is not recommended due to the lack of accurate data regarding the safety and effectiveness of therapy.

For adults

Requires careful use:

• for psoriasis;
• depression;
• bronchospasm;
• angina pectoris;
• disorders of the kidneys and liver;
• diabetes mellitus;
• old age.

Pregnancy and breastfeeding

Despite the fact that the drug does not have a direct cytological and mutagenic effect on the body, some pharmacological effects can negatively affect the course of pregnancy.

According to statistics, beta-blockers, by reducing placental perfusion, slow down fetal development or provoke intrauterine death, leading to miscarriage or premature birth.

Taking Bisoprolol is also not recommended during breastfeeding. To date, there is no reliable information about the possibility of its penetration into breast milk.

Bisoprolol reviews. Advice and reviews from doctors about the drug Bisoprolol for use

Latin name: Bisoprolol. Manufacturer: Sandoz, Merkle GmbH for “Ratiopharm GmbH” Germany PJSC Lugansk Chemical Plant, Ukraine LLC “PRANAFARM”, CJSC “Northern Star”, Rompharma, Vertex, Biocom, Atoll, Russian Federation Teva, Israel.

Its action is aimed at relieving the symptoms of myocardial ischemia (antianginal effect), normalizing the disturbed rhythm of contractions of the heart muscle (antiarrhythmic effect), as well as reducing blood pressure (antihypertensive effect).

Active substance

: Bisoprolol fumarate

Doctors' opinions, What people write, Forum

Hello! Blood pressure 108/67, pulse 88, weakness. Can I take bisoprolol or will it lower my blood pressure? What to do?

Good evening, I’m briefly taking bisoprolol 1.25 recently, severe weakness, apathy, I want to quit, but the attack relieves, you can take it as an aid, and not every day. Hello, I’ve been taking bisoprolol for about 5 years, it was prescribed to me by a therapist. There was Graves' disease and thyrotoxicosis. I took a course of treatment with tirazole and thyraxine for 3 years, then I had my blood tested and everything returned to normal, but I still often have heart palpitations, t... Pulling and other sensations in the legs - a side effect of the medications? Good afternoon I had complaints of slight arrhythmia and tachycardia, as well as headache and slight dizziness. According to tests and ultrasound, everything is normal. But my therapist prescribed: Concor cor (2.5 mg bisoprolol once a day)

Preductal MR (Trimetazidine…

Hello, I take Lorista N 25 mg plus 2.5 Bisoprolol or 2.5 Concor in the morning. Now I added Panangin on the doctor’s advice 3 rubles. per day for 10 days. Question about dose. In the morning the pressure is consistently low (on average 100/60), and in the evening it rises (but not always) in... Is it possible to take bisoprolol with a pulse of 54? The pressure is usually 104/64 and the pulse is 54-56. It began to rise to 140, but the pulse was less than 60. ECG and ultrasound of the heart were normal. Holter also did not reveal anything significant. Bisoprolol 2.5 mg was prescribed in the morning. At the same time, the pressure decreases, but so does the pulse, to 50-51. Can... Hello, I take bisoprolol every day, can this cause me to gain weight? thank you in advance. Good afternoon doctor. I am 31 years old and a mother of 3 children. Somewhere in February, due to nervousness, my blood pressure has been rising, my pulse has increased, and I have panic attacks. I went to see a neurologist and was prescribed Grandexin, and things started to feel better. And with the pressure, I went to see the SKA therapist... Hello, I was given the diagnosis indicated during the Holter test. During a long-distance consultation, our cardiologist left, having managed to prescribe only one drug before the Holter, bisoprolol. I was not prescribed any further treatment. Please tell me... Sleep disturbance, difficulty falling asleep Good afternoon! Over the past 3-4 years, my sleep patterns have been disrupted. Before that, my constant sleep schedule was from 22-23 to 5 am. Now I go to bed at the same time (22-23 hours, but I fall asleep somewhere after 2-3 hours until 7 – 8 am.. It turns out 3 – 4 hours “I” me... Hello. My mother is 86 years old. She is disabled due to vascular Parkinson's. Two years ago she suffered a stroke. Despite constant therapy, her blood pressure often rises to 190-180/90-100. In the morning, the pressure is low 120/60. But within an hour... Mom is 83 years old. Working pressure is 130-140x80. She took Betalok zok 5 mg. 2 times a day. Cholesterol and sugar are normal. After undergoing laser correction of secondary cataracts , pressure jumps like crazy. In the morning 110-128x60-75. lunch maybe 135 148x 7690, and in the evening... Good afternoon. My name is Dmitry. The problem is that I have diabetes mellitus (pancreatogenic) and secondary dysmetobolic, arrhythmogenic cardiomyopathy. Cardiologists prescribed me Biosotal 80×3 per day, since it did not help it was cancelled. After... Hello. I have been suffering from panic attacks for the second year. The last time I was in the hospital (therapy), my blood pressure was leveled, and osteochondrosis of the cervical spine was treated. Regarding the attacks, I consulted a psychiatrist. Alprazolam and Sertraline (Zoloft) were prescribed.

Is it possible in parallel...

Hello! please tell me, I am 32 years old, male, I take Concor 10 mg 1 tab. In 1-2 days over the course of 5 years, I began to notice that the pressure had normalized, but was still elevated, without the tablets 140/80 with the tablets 120/70. Should I continue taking... Question to the doctor about taking bisoprolol Hello! In 2017, after donating blood, she fainted. There was fog and the pressure was high. I had a thyroid ultrasound and saw a psychiatrist and a neurologist because I was living in a fog. Ultrasound shows signs of a cyst in the left lobe of the gland. the neurologist prescribed glycine, afobazole, mexido... Hello, I’m 27 years old. Already 7 years old. I’m worried about tachycardia, or rather, it’s probably already a dependence on nie and Bisoprolol. It all started with the fact that in the summer I was in a car accident, where I had a severe bruise on the left side in the heart area. Tachycardia appeared... Is it possible to take bisoprolol every other day? Hello. I have sinus tachycardia, the average resting heart rate is 95-110 beats per minute. I take bisoprolol 2.5 mg tablets. In general, to maintain a normal pulse, one tablet every 2 days is enough for me, and not every day, after all, they have enough... Replacing medications during pregnancy, indapamide and bisoprolol Good afternoon! I am planning a pregnancy in the near future. For two years I have been taking indapamide 150 and bisoprolol due to a constant increase in blood pressure (not higher than 138-140) and a rapid pulse, the drugs were prescribed by a therapist at the clinic. What to replace e... Question to the doctor about taking medications. Hello, my diagnosis: asymmetric hypertrophic cardiomyopathy with predominant hypertrophy of the interventricular septum (intraventricular MHD gradient 115 mm Hg) Stage 3 arterial hypertension with heart damage. Atheroscle... Treatment of ventricular extrasystole Hello. During Holter monitoring, ventricular extrasystole (2000 per day) was detected. I am 27 years old, I have led a sporty lifestyle since childhood, I have no bad habits, I watch my diet, and for the last 4 years I have been doing intensive training... Hello! I was suffering from theriotoxicosis, the doctor prescribed anaprilin, I took it for three months; over time, I began to sleep poorly and had stomach problems. I went to a cardiologist, he prescribed me bisopoolol instead of anaprilin, I felt good for a week then... Good afternoon! I was in the hospital for 8 days with a diagnosis of RBBB. I take Bisoprolol 1.25 mg in the morning with Mildronate 500 mg. Are these drugs compatible? Hello, I want to ask you, doctor, why it’s hard for me to breathe when lying on my back. I saw a cardiologist, the doctor said that there was nothing wrong, the cervical arteries were slightly damaged, but overall everything was fine, he prescribed IVs, and I took some eye drops. S... Question to the doctor about taking medication for the heart Hello, I had pressure in the area of ​​my heart, the pressure was 138 over 90, the pulse was 85, it was hard to breathe, it seemed like there was not enough oxygen. They did an ECG and said it was normal, like it was a nervous condition. They prescribed glycine 1 t. 3 times a day, riboxin as well... Question to the doctor about taking medication for the heart Hello, I had pressure in the area of ​​my heart, the pressure was 138 over 90, the pulse was 85, it was hard to breathe, it seemed like there was not enough oxygen. They did an ECG and said it was normal, like it was a nervous condition. They prescribed glycine 1 t. 3 times a day, Riboxin as well... Hello. My son was prescribed to take bisoprolol. But to be honest, I'm afraid to give it. The fact is that my son has a psychiatric illness and constantly takes psychotropic medications. Is bisopropol compatible with them? Especially so... Hello, I was diagnosed with VSD, hypertension, my blood pressure rose to 160/120, I am 33 years old, I was prescribed to take Prestilol, after taking the drug my blood pressure was normal, but I developed tinnitus, headaches, pain in the temples of the eyes, confusion... Hello , I was diagnosed with VSD, hypertension, my blood pressure rose to 160/120, I am 33 years old, I was prescribed to take Prestilol, after taking the drug my blood pressure was normal, but I developed tinnitus, headaches, pain in the temples of the eyes, confusion... Good afternoon. Is it possible to take alcohol in small quantities while treating with bisoprolol? Severe takardia and ekstrocystole from Cavinton I have dystrophy of the vessels of the head, my head is very heavy, I take Cavinton, it helps very well, my hearing and vision improves, I am starting to think clearly, but at the same time, takikardia is crazy and ekstrocystole begins at night, bisoprolol does not help, his cardiologist discharged him... I have osteochondrosis of the cervical-thoracic spine. I have been suffering from heart failure for two years. Sometimes, against the backdrop of absolute calm, it becomes bad, pinching somewhere in the area of ​​the shoulder blade. For about a year now, I have been tormented at times by the feeling of lack of air. Heart transplant - diagnosis of taking medications. My husband had a coronary angiography in Monica and all sorts of other things. Result of heart transplant. Question: if the normal blood pressure is 120/80, should I take the prescribed medications? After them it decreases to 105. Previously, the diagnosis was Artemia atrial fibrillation. For arrhythmia, take medicine constantly... Refusal to take the drug Hello. I have been taking bisoprolol for five months now, my blood pressure has stabilized, but I have headaches and weakness, how can I stop taking it? I heard that you shouldn’t suddenly stop drinking it, tell me how to stop taking the pills correctly Hello. I’ve been drinking 1.25 bisoprolol for a month now, I wanted to stop drinking and they diagnosed NCA Cardiac type. I don’t feel very well, stabbing pain in the heart area, can I switch to 2.5 bisoprolol or stop drinking it altogether. Vasospastic angina The doctor prescribed bisoprolol and lercanidipine to a patient with vasospastic angina. But the annotations for the drugs indicate contraindications for unstable angina. What guides you - the doctor’s prescription or the instructions for the medications? Hello. The doctor prescribed bisoprolol in the morning due to panic attacks and tachycardia. This morning the pressure is low. I feel weak and drowsy. Tell me, is it worth taking bisoprolol today? Incomplete sinoatrial block, 2nd degree Hello. One incomplete sinoatrial block was recorded on Holter monitoring per day. I take bisoprolol at a dosage of 2.5 mg. Can I use it? Or cancel. I can’t cancel, I’m tormented by tachycardia. Hello, I’m 23, I’ve been taking bisoprolol for 2.5 years (VSD, NCD, hypertension, tachycardia, panic attacks) - all my diagnoses. It suits me better and my pulse and blood pressure are normal. So I need to remove a small boil (they did it for me once, but then... Good afternoon! A 66-year-old woman, in November 2017, had a hypertensive crisis, 9 years ago had a microstroke. There were several crises. All against the background of not very high blood pressure - upper 150- 160. He takes bisoprolol 2.5 mg as a background. Normal blood pressure is 135 to 85-90. What... I am hypertensive, I constantly take medications for blood pressure. Lately blood pressure has been jumping from 140-150/90-110 to 110-100/70 pulse 50- 70. Should I take daily pills when all hell is falling? Tachycardia + hypertension in a 29 year old man Hello! My husband has tachycardia (pulse 115 at rest) and stage 1 hypertension (about 142 over 94). He is 29 years old. Symptoms: very strong pressure pain in the back of the head, sometimes dizziness, everything hurts at night, can’t sleep because... Question about drug compatibility Hello. My mother was diagnosed with arrhythmia, and something else, she was in cardiology 2 times, but nothing helped, constant shortness of breath and There was high blood pressure. The local cardiologist prescribed 5 types of medications to take for life, but on the 3rd day she began to have... Rapid pulse, do I need to take medications? Hello! My name is Mila. I am 47 years old. Had a medical examination. ECG is normal. The pressure is also normal. I feel normal. Pulse 86-90 beats per minute. Do I need to take bisoprolol to lower my heart rate? Should I take bisoprolol before Holter monitoring? Good afternoon. Every day, according to the doctor’s recommendations, I take Bisoprolol 2.5 mg. A 24-hour Holter monitoring is scheduled for tomorrow; I didn’t think to ask my doctor in advance whether it is necessary (and whether it is possible) to take Bisoprolol in the morning as usual. Should... Effect of drugs on sperm quality Hello. I am being treated for nervousness, Trileptal, bisoprolol, Fezam, Cipralex, quetiapine. Please tell me how these medications can affect the quality of sperm. I was prescribed to drink for 3 years. There are two left, my wife and I want to conceive a child! Or is it worth taking Bisoprolol after a heart attack After a heart attack (April 2016), along with other medications, I constantly take Bisoprolol 2.5 mg. Heart rate is usually 55-65. But in the evening and at night it is often within 48-52 beats. Should I worry and stop taking bisoprolol? By the way, at a low heart rate I give...

Source: https://puzkarapuz.ru/review/detail/bisoprolol_otzyvy_sovety_i_otzyvy_vrachej_o_preparate_bisopr

Contraindications

• intolerance to components;
• cardiogenic shock;
• atrioventricular block II and III degrees;
• arterial hypotension;
• cardiomegaly;
• peripheral circulatory disorders;
• heart failure;
• Raynaud's syndrome;
• concurrent use of antipsychotics;
• pregnancy;
• patient age under 18 years;
• collapse;
• weakness of the sinus node;
• bronchial asthma;
• alcohol consumption.

Side effects

Concor or bisoprolol: which is better and what is the difference (differences in composition, reviews from doctors)

Despite the fact that Concor and Bisoprolol belong to the same group of drugs, these drugs have some differences, and in order to understand the difference between them, it is necessary to analyze each one.

What is Bisoprolol?

Bisoprolol is a selective (selective) β-blocker. This means that this drug selectively blocks β1-adrenergic receptors, which are found in the heart and blood vessels.

Normally, the effect of adrenaline (a hormone produced by the adrenal glands in stressful situations) is an increase in blood pressure due to vasoconstriction and an increase in cardiac output (the amount of blood pushed out by the heart during one contraction).

When β1-adrenergic receptors are blocked with Bisoprolol, these effects do not develop.

Bisoprolol and Concor: what is the difference between them?

The differences between these drugs are insignificant, since both medications contain the same active ingredient - bisoprolol (Bisoprolol (medicine) is a generic drug - a copy of Concor).

Composition and pharmacological properties

Both drugs contain bisoprolol fumarate as an active substance. This compound blocks β1-adrenergic receptors, which leads to vasodilation, a decrease in heart rate (HR) and a decrease in cardiac output. Due to the fact that the heart begins to contract less actively, the cells' need for oxygen decreases.

Indications

What are these drugs used for? Bisoprolol and Concor work best when:

• arterial hypertension (increased blood pressure);
• hypertension (persistent increase in blood pressure);
• coronary heart disease (a disease that is accompanied by vasoconstriction, due to which oxygen starvation of cells develops);
• angina pectoris (a sharp narrowing of the blood vessels of the heart, which leads to severe pain in the chest).

Contraindications

It is better not to use both medications if:

• heart failure (a condition in which cardiac output is reduced);
• arrhythmias (bradycardia - decreased number of heart contractions, atrial fibrillation - asynchronous contractions of the heart due to the appearance of additional foci of excitation in the heart muscle);
• severe course of bronchial asthma;
• hypersensitivity to the components of the drug.

Side effects

When using Concor and Bisoprolol, patients often complain of:

• bradycardia;
• arrhythmia and palpitations;
• dizziness;
• weakness;
• headache;
• hearing impairment;
• bronchospasm (sharp narrowing of the lumen of the bronchi);
• vomiting, diarrhea, feeling of nausea;
• convulsions.

Release form, price, manufacturer

The main differences between Concor and Bisoprolol are price, release form and country of origin.

Price and release form

Bisoprolol is produced in the form:

• tab. 2.5 mg, 30 pcs. – 94 rub.;
• tab. 5 mg, 30 pcs. – 97 rub.;
• tab. 10 mg, 30 pcs. – 113 rubles;

Concor is available in the form of:

• tab. 5 mg, 30 pcs. – 228 rub.;
• tab. 5 mg, 50 pcs. – 274 rub.;
• tab. 10 mg, 30 pcs. – 338 rubles;
• tab. 10 mg, 50 pcs. – 504 rub.

Manufacturer country

As you can see, the price for Concor is on average 2-3 times higher. This is due to the fact that it is produced abroad.

Concor or Bisoprolol, which is better?

If the drugs do not differ in their mechanism of action, which of these drugs is better to take in the treatment of diseases of the cardiovascular system? It is impossible to say unequivocally which drug of these two is more effective, since they both contain the same active substance.

However, doctors more often prescribe Concor to patients, because it is believed that the quality of imported drugs is slightly better. Can it be replaced with Bisoprolol? The answer to this question is positive, because the mechanism of action of Bisoprolol is the same.

But it is worth remembering that generic drugs differ in effectiveness (by about 5-15%) from the original ones, this is due to cheaper production technology.

Which is better Concor or Bisoprolol: reviews

To understand which medication is better, you need to read the reviews of patients who have used them.

Concor and Bisprolol: what is the difference and which drug is better?

For many years, cardiovascular diseases have held the palm among diseases that often lead to death. Moreover, stroke and heart disease are getting younger year by year.

The main risk factors are poor diet, stress, physical inertia, tobacco and alcohol use.

The danger of the disease is that it may not make itself felt for a long time, but may appear spontaneously. People suffering from CVD need early diagnosis and treatment with medications.

Doctors are increasingly prescribing Concor or Bisoprolol for the treatment of heart disease. Which is better and what is the difference between these medications? To resolve this issue, it is necessary to study the composition of both medications.

Bisoprol and Concor: what is the difference between them?

Bisoprolol and Concor are medications from the group of beta blockers that are widely used to treat hypertension and cardiovascular diseases: heart failure; coronary heart disease; heart rhythm disturbances; prevention of angina attacks.

Concor and other bisoprolol preparations have significant advantages that have made them very popular among patients and doctors.

Compound

The composition of the medicines includes the main active ingredient – ​​bisoprol. That is why they act almost identically. Their effectiveness is at the same level.

Contraindications for use and side effects are also similar. So what is the difference between Concor and Bisoprolol? They differ only in the manufacturer and price. Bisoprolol is a domestic analogue of Concor. When comparing Concor or Bisoprolol, the price difference is quite significant. The Russian drug costs slightly less than its foreign counterpart.

Advantages

The advantages of the drugs over other drugs are the following:

• It is enough to take Concor and Bisoprolol once a day. One tablet will provide the patient with stable blood pressure for a day;
• taking medications does not depend on food intake;
• These beta blockers have fewer side effects than their predecessors;
• medications do not affect potency in men;
• affordable price.
• Bisoprolol and Concor are metabolically neutral drugs. They do not affect the metabolism of cholesterol, triglycerides and glucose in the blood. They are safely prescribed to patients with type 2 diabetes and the elderly.

How do medications for hypertension work?

The drugs in question for hypertension act much more consistently than other medications and keep blood pressure at the desired level.

Daily blood pressure monitoring showed that after taking Bisoprolol or Concor tablets, the blood pressure remains normal in the morning of the day following administration.

Other beta blockers reduced or completely stopped their hypotensive effect 4 hours before taking the next dose of the drug.

These medications can effectively control blood pressure and heart rate not only at rest, but also during exercise. In this regard, they work better than, for example, Metoprolol. The most important feature of drugs is the stability and uniformity of their action throughout the day.

For severe hypertension, combinations of Bisoprolol with other medications are prescribed: diuretics, ACE inhibitors, and other drugs for hypertension. It was found that the blood pressure lowering effect of Concor and Bisoprol remained stable over the 3 years that the study continued.

Treatment of chronic heart failure

Both medications are useful for chronic heart failure of various origins.

The drugs significantly reduce the risk of sudden death, the frequency of re-hospitalization, and also improve the quality of life of patients.

If you have the slightest ailment associated with increased blood pressure, such as frequent headaches and dizziness, spots flashing before your eyes, as well as if you experience aching or stabbing pain in the sternum, shortness of breath, it is important to consult a doctor in a timely manner.

How to take beta blockers correctly?

For different diseases and depending on the patient’s condition, the dosage of drugs may be different:

• for hypertension, the initial dose is 5 mg per day, gradually increasing it to 10 mg per day;
• for coronary heart disease, the dosage ranges from 2.5 to 10 mg per day. It is selected strictly individually until the pulse rate reaches 50-60 beats per minute;
• for chronic heart failure, medications are prescribed in addition to therapy with diuretics and ACE inhibitors. The initial dose is 1.25 mg per day.

Concor: benefits and harms during pregnancy and lactation

It is Concor that is most often prescribed to expectant mothers for the treatment of arterial hypertension.

Any beta blockers reduce blood flow in the placenta, and this negatively affects the development of the unborn baby.

It is recommended to stop taking Concor 3 days before the expected due date.

After the birth of the child, he needs to be carefully examined. The newborn may experience symptoms of bradycardia and hypoglycemia.

Interaction between alcohol and Bisoprolol

Alcoholic drinks can affect the functioning of any medication.

This is due to the fact that both alcohol and medications undergo processing in the liver, and this negatively affects its work.

Bisoprolol and Concor should not be combined with alcoholic beverages.

During their interaction, the functioning of the heart is disrupted. In this case, arrhythmia and pain in the heart area occur. Alcohol can significantly increase blood pressure. Even a small dose of alcohol during therapy can cause a sedative effect: a feeling of emotional depression, severe lethargy.

Analogs

There are many analogues of these drugs available on the pharmacy market:

1. Biprol;
2. Bisogamma;
3. Niperten;
4. Bisoprolol-Lugal;
5. Bisoprolol-Prana;
6. Bisoprolol-ratiopharm.

Each manufacturer of Bisoprolol analogues tries to convince doctors that their drug meets international quality standards and is not inferior in its effect to the original Concor.

Every doctor has his own opinion on this matter. When prescribing a drug, he is guided by practical experience and the patient’s condition.

Side effects

Bisoprolol and Concor are tolerated by patients much better than older generation beta blockers.

Side effects when taking beta blockers are still possible and they manifest themselves in the following:

• from the central nervous system: weakness, fatigue, dizziness, headaches, nightmares, anxiety;
• from the senses: vision problems, conjunctivitis, dry and sore eyes;
• from the cardiovascular system: bradycardia, rapid heartbeat, cardiac arrhythmias, arterial hypotension;
• from the digestive system : nausea, abdominal pain, constipation or diarrhea;
• from the endocrine system: weakened thyroid function;
• allergic reactions: rash, urticaria, itchy skin.

on this topic

Specialist on what is better: Concor Ilm Bisoprolol, what is the difference between the drugs:

Bisoprolol and Concor are modern selective drugs from the group of beta blockers. They have proven high effectiveness in the treatment of hypertension and cardiovascular diseases. Side effects are relatively rare and are well tolerated by patients.

It is these medications that lower blood pressure to the desired level, reduce the frequency of angina attacks and manifestations of heart failure. Timely treatment with beta blockers prescribed by a doctor will reduce the risk of stroke and heart attack. The difference between Concor and Bisoprolol is only in the manufacturer and price. Bisoprol is a domestic drug.

In Russia, it is included in the Federal program of preferential drug provision for patients.

Bisoprolol or Concor: which is better, reviews, difference

What is better and more effective - Bisoprolol or Concor? Which drug has fewer side effects? What is the difference? Similar questions are asked by those patients who are faced with elevated blood pressure (hypertension), heart failure, ischemia, angina pectoris and other diseases.

Source: https://davlenie-vnorme.ru/otzyvy/konkor-ili-bisoprolol-chto-luchshe-iv-chem-raznicza-otlichiya-sostavov-otzyvy-vrachej

Overdose

Exceeding the dosage of Bisoprolol prescribed by the attending physician causes the patient to:

• dizziness;
• arrhythmia;
• acrocyanosis;
• ventricular extrasystole;
• bradycardia;
• AV block;
• decrease in blood pressure;
• acute heart failure;
• hypoglycemia;
• fainting;
• labored breathing;
• bronchospasm;
• convulsions.

A patient who has exceeded the dosage should immediately undergo gastric lavage, give an adsorbent and prescribe symptomatic therapy. In this case, the use of Bisoprolol is completely canceled.

special instructions

It is important to know not only how long you can take Bisoprolol, but also some other nuances.

The drug can be used with extreme caution in the development of psoriasis, diabetes mellitus, as well as in cases of a person’s predisposition to various allergic reactions.

If the patient has pheochromocytoma, then the drug is prescribed after taking alpha-blockers.

Before performing operations, the anesthesiologist should be told about taking Bisoprolol. If a person’s work involves concentrating, then it is better to stay at home during treatment, as the speed of the psychomotor reaction may decrease.

Drug interactions

The tolerability and effectiveness of the drug are influenced by drugs taken simultaneously or over a short time interval. Let's give an example of the interaction of some drugs with Bisoprolol:

• class I antiarrhythmic drugs, when used simultaneously, reduce AV conductivity and the ability of the myocardium to contract;
• class III antiarrhythmic drugs - increase AV conduction disturbances;
• beta blockers - reduce blood pressure and heart rate;
• parasympathomimetics - increase AV conduction disturbances, increasing the risk of developing bradycardia;
• taking Bisoprolol simultaneously with beta-agonists will reduce the effectiveness of both drugs;
• combination with adrenomimetics will enhance the vasoconstrictor effect of both drugs, leading to an increase in blood pressure and the risk of developing bradycardia;
• allergens, as well as iodine-containing diagnostic agents, increase the risk of severe systemic allergic reactions and can cause anaphylactic shock;
• treatment with Bisoprolol will make the symptoms of developing hypoglycemia invisible during insulin therapy;

• cardiac glycosides - provoke cardiac arrest or heart failure, creating a risk of developing bradycardia and AV block;
• tri- and tetracyclic antidepressants will increase the effect on the central nervous system; Antipsychotic drugs behave similarly;
• Ergotamine - creates a disturbance in the peripheral circulation;
• Sulfasalazine - will increase the saturation of blood plasma with Bisoprolol;
• Rifampicin will speed up the period of elimination of Bisoprolol from the patient’s body.

Bisoprolol (Concor, Coronal)

pages:

Answers from the site author to typical requests from page visitors

Concor – review from a cardiologist

Table of analogues and prices

Concor (original Bisoprolol) - official instructions for use (abstract)

Article by the site's author, a cardiologist, on the treatment of hypertension

All about blood pressure monitors

Which is better - Concor or Concor Cor?

This is the same drug, produced by the same manufacturer, only the dosage is different - the Concor tablet contains 5 or 10 mg, and Concor Cor - 2.5 mg.

Compare Aritel core and Concor core

Whatever one may say, Concor (5 and 10 mg) and Concor Cor (2.5 mg) are the original drug, and everything else is copies of different manufacturers. So the answer is clear - if you have enough money, buy Concor.

Review from a cardiologist about the drug Concor:

Concor is one of the favorite cardiac drugs among both doctors and patients.

For some part of my life I had the opportunity to work in a state clinic, and the annual supply of the original Concor for issuing free prescriptions ran out by September.

The main positive qualities of Concor:

• Duration of action. Concor works stably throughout the day, which makes a single dose possible without fear of “failures” in the effect.
• “Softness” of action. Smooth start, minimum side effects, in my opinion, among all beta blockers.
• Sufficient number of release forms. Unlike many beta blockers, Concor comes in three strengths (2.5, 5 and 10 mg), and the heart tablets break easily in half, allowing for easy and precise dosing.
• Strong antiarrhythmic effect. The antiarrhythmic effect of Concor is not prescribed in the official instructions, but practice shows that this drug has an excellent effect on all types of extrasystoles and paroxysmal tachycardias for the prevention of attacks. Also, the effectiveness of Concor in atrial fibrillation (atrial fibrillation) in terms of maintaining sinus rhythm in a paroxysmal (paroxysmal) form, in my opinion, is the best among beta blockers.

And one more argument for the quality of the drug is the number of copies. Bad drugs are not copied.

To understand the quality of analogues, read the corresponding article.

Sincerely, the author of the site.

Analogs

Medicines with similar effects:

• Betak, Betacard.
• Vasocardin.
• Corvitol.
• Lokren.
• Metozok, Metokor.
• Nebivator, Nebivolol, Nevotens.
• Serdol and Estekor.

Generics of the active substance:

• Aritel.
• Bidop, Bisocard.
• Concor, Cordinorm.
• Niperten and Tirez.

Reviews

Expert opinion
Vasily

Reader

I tried many medications and none could help as much as Bisoprolol did. I bought it on the advice of a friend. When I saw the price of 30 rubles, I was delighted at such an affordable price. It's good that I decided to try it.

Expert opinion

Tamara

Site reader

I took a bisoprolol tablet and my blood pressure stabilized in about 30 minutes. It’s a cheap and extremely effective remedy. There were no side effects, despite the reviews of my friends about the drug.

Video on the topic

Is it possible to take Bisoprolol in the evening? Is it possible to take Bisoprolol with low blood pressure? How to take Bisoprolol for tachycardia and high blood pressure? Answers in the video:

Bisoprolol is a fairly serious drug that has a large list of advantages, but no less a list of contraindications and side effects. The dosage and frequency of administration should be strictly observed. Only a professional doctor can prescribe the drug and draw up a treatment regimen. Self-medication is strictly not recommended.