Electrophoresis with nicotinic acid: description of the procedure, indications and contraindications, action, reviews

Composition, release form, where to buy and price

The medicine is available in 2 dosage forms - tablets and solution for parenteral administration and other routes of administration. The tablets are small in size, white in color, and round in shape. They are packaged in blisters of 10 pieces. The cardboard box may contain 1 or 3 blisters, as well as instructions for the correct use of the medication.

The solution is colorless, transparent, packaged in ampoules of 5 or 10 ml. Individual cardboard packaging can contain 5 or 10 ampoules. They always come with instructions for using the medicine. The solution and tablets contain the substance aminophylline as the main active ingredient.

The tablets contain talc, starch and other active ingredients. The solution additionally contains water for injection. You can purchase the product at the pharmacy with a prescription from your doctor. Its cost ranges from 50-120 rubles. depending on the number of tablets or ampoules in the package.

Technique of the procedure

The procedure is quite simple.
Conducted by a health professional in a physiotherapy room. Instructions for the use of aminophylline for electrophoresis are drawn up by a doctor. Basically, they take the medicine in ampoules with a concentration of 2.4 percent. In addition to the device, you need suitable electrodes and wipes. Before use, the latter is moistened with the necessary solution, prepared in advance. Then they are placed on the desired areas of the body and the electrodes are immersed there. The first gasket to the pole is with a plus, the second with a minus. The patient should be covered during the procedure. Throughout the session, the current strength is controlled (it is increased gradually) and the duration of action. It is necessary to monitor the patient's well-being. Normally, he may feel a slight tingling sensation at the sites where the electrodes are applied. If pain or discomfort occurs, the procedure should be stopped and your doctor informed. On average, the course of therapy lasts 10-14 days. Conducted every day or every other day. Duration – 20 minutes for adults and 10 for children.

There are other ways to deliver aminophylline during electrophoresis to the desired area of ​​the body:

• bath - the solution is poured into a container with built-in electrodes and the desired part of the body is lowered into it;
• cavity - medicine and one of the electrodes is inserted into the cavity, and the second is attached to the skin;
• interstitial - aminophylline is taken in the form of tablets or intravenously, and electrodes are placed on the diseased organ.

It should also be said that “bipolar” electrophoresis is possible. For this, two substances of different polarity are used. For example: papaverine, nicotinic acid.

Mechanism of action

Eufillin solution (for electrophoresis and other procedures, the product is used only as prescribed by a doctor) has several pharmacological properties. Its mechanism of action is based on the ability to block purine receptors of bronchial smooth muscle fibers.

In addition, the medicine reduces the contractility of the muscles of the organ, which leads to a reduction in the risk of developing an attack in chronic obstructive pathologies of the respiratory system.

As a result, the patient's condition improves and the progression of the pathological condition slows down. Additionally, the active substance of the drug stimulates kidney function, which increases daily diuresis. The antispasmodic properties of the drug can reduce bronchospasm and also facilitate breathing for patients with obstructive disorders.

The drug also has a stimulating effect on the diaphragm, the respiratory center, which improves the patient’s breathing, making it deeper and easier by facilitating the functioning of the intercostal muscles.

The medicine improves alveolar ventilation, which leads to improved oxygen supply to the tissues of the whole body. By improving the nutrition of myocardial tissue, the risk of developing a heart attack, as well as coronary artery disease and angina, is reduced.

Additionally, the medication dilates peripheral vessels, which improves blood flow to internal organs.

When using the medicine, there is a slight decrease in blood in the pulmonary circulation, which makes breathing easier for asthma and other pathologies of the bronchi and lungs. The diuretic effect of the drug is explained by the ability of the drug to increase blood circulation in the kidneys.

There is a moderate effect of the drug on the bile ducts. Contributing to their expansion. The medicine also reduces the contractility of the myometrium, which has a positive effect on various diseases of the female reproductive system.

When using the solution, the active component spreads quite quickly through the systemic bloodstream and has a therapeutic effect. It is worth noting that when taking tablets, absorption is also rapid; absorption occurs in the digestive tract, namely in the small intestine.

Aminophylline is approximately 60% bound to plasma proteins. This bioavailability indicator is not considered high, but the product is highly effective despite it. After spreading through the systemic bloodstream, most of the active substance is concentrated in the lung tissue, which explains the high efficiency.

Experts note that in patients with liver cirrhosis, the bioavailability of the active component does not exceed 35%. Despite this, the medication is well absorbed, but the effectiveness is somewhat reduced.

After the active substance is processed in the liver, it is eliminated. The evacuation period takes up to 2 days, depending on the characteristics of the patient’s body. In patients with mild liver damage, excretion is slightly prolonged. The main amount of the active substance is evacuated by the kidneys, a small part is excreted in the feces.

It is noted that absorption and excretion depend on the dose taken and duration of use of the drug. When using the drug for electrophoresis or inhalation, absorption into the systemic circulation is negligible. This makes it difficult to study pharmacokinetic properties.

Carrying out the procedure

The technique of electrophoresis itself is quite simple. It consists of placing napkins moistened with a solution on the desired area of ​​the body, correctly positioning the electrode on it, tracking the procedure time and adjusting the current strength. All this is done according to the instructions received from the doctor.

The electrodes are placed strictly on the napkin or pad, without protruding beyond its limits. The pad itself should be damp, but not too wet. The arrangement of the electrodes depends on which electrophoresis technique is used.

Related articles: Main apparatus for electrophoresis

Basic techniques

• general electrophoresis (according to Vermeule);
• ionic collar;
• ion belt;
• electrophoresis according to Shcherbak;
• nasal;
• orbital-occipital, etc.

Each technique has its own electrode arrangement. But for the most part they are located in the spine. This may be the cervical, thoracic, lumbar or sacral region. Also often one of the electrodes is placed on the limbs. In children, the nasal location is used, since the nasal cavity is connected to many organs. There are specifics in dentistry and other areas.

Once the electrodes are properly positioned, you can turn on the device. The current strength is set to the minimum level. Electrophoresis should not cause any discomfort. Gradually, the current strength is increased by turning the rheostat. If unpleasant, painful sensations appear, you must stop, even if the maximum value has not been reached.

The duration of the procedure may vary. It depends not only on the disease, but also on the age and condition of the patient. As a rule, it lasts from 5 to 20 minutes. Exceeding this time is undesirable. After the end of the session, you can give the patient a little rest.

Despite the safety of this treatment method, such as electrophoresis, all prescriptions and recommendations, namely the number of sessions, their duration, minimum and maximum current strength, active substance and its concentration, are determined only by the doctor. Self-medication can lead to very unpleasant consequences.

Indications for use

Eufillin solution (for electrophoresis, the drug is used after examination) is indicated for a variety of diseases in adults and children.

The main indications for use are the following:

• Cerebrovascular insufficiency with brain damage and severe symptoms.
• Increased blood pressure in the pulmonary circulation.
• Bronchial asthma at different stages.
• Obstructive forms of bronchitis, which aggravate the condition of the bronchi.

• Chronic bronchitis with frequent relapses.
• Migraine with regular exacerbations of the condition.
• Left ventricular failure in patients with chronic diseases of the cardiovascular system.
• Bronchospasm due to inflammatory pathologies of the bronchi and lungs.
• Emphysema. In this case, the medication can be used for acute and subacute pathology, which occurs as an independent disorder or against the background of other diseases.
• Chronic obstructive pulmonary disease in patients whose professional activities involve regular contact with dust or harmful substances.
• Pathologies of joints and bones, for example, osteochondrosis, arthrosis.

The solution can also be used as part of a complex treatment of other diseases, but only as prescribed by a doctor.

Use of aminophylline with nicotinic acid

The main effects of vitamin PP:

• Improving carbohydrate metabolism, an aid for type 2 diabetes mellitus, diseases of the liver, stomach, heart and blood vessels
• Acceleration of regeneration of skin and mucous membranes
• Vasodilating effect - expansion of peripheral blood vessels of the body
• Reducing the level of bad cholesterol in the blood.

Basically, the combination of aminophylline with vitamin PP is indicated for severe hypertonia and muscle hypotonicity. This combination is also prescribed to infants in the presence of hydrocephalic syndrome and as an adjuvant for the treatment of postpartum injuries. In addition, vitamin PP is used to treat gastritis, colitis and stomach ulcers with low acidity, atherosclerosis, coronary heart disease, trophic ulcers, and vascular spasms. Long-term treatment is not recommended, as there is a risk of fatty liver degeneration.

Why can Eufillin be prescribed during pregnancy?

During pregnancy, the medicine is used quite often, especially during a difficult period. This treatment is prescribed for toxicosis, as well as increased blood pressure.

For placental insufficiency and severe swelling of the extremities, the drug is also prescribed. This is due to the ability of the solution to stimulate blood circulation in the myometrium, as well as improve blood circulation in the kidneys, which increases daily diuresis and helps eliminate edema.

There is no specific scheme for using the product during pregnancy, since the official instructions are considered a contraindication. However, the experience of many specialists proves that if the dose is chosen correctly and all rules are followed, the drug can benefit the pregnant woman and alleviate the condition.

Contraindications and side effects

Eufillin solution and tablets are not used for inhalation, electrophoresis and other methods when an allergy to the components of its composition is detected.

There are other contraindications for therapy:

• A severe form of renal failure in which the functioning of the organ is severely impaired.
• Acute myocardial infarction and severe angina.
• Atherosclerotic changes in blood vessels.
• Pulmonary edema due to cardiac pathologies.
• Acute peptic ulcer of the duodenum and stomach.
• Epilepsy with regular seizures.
• Stroke of hemorrhagic type.
• Uncontrolled hypertension or hypotension. The drug is not contraindicated in mild cases of such diseases, but in case of frequent relapses and attacks it should not be used.
• Hemorrhage in the retinal tissue of the visual apparatus.
• Disorders of the thyroid gland, manifested in the form of thyrotoxicosis or hypothyroidism.
• Sepsis in acute or subacute form.
• Acute bleeding, the presence of similar disorders in the patient's medical history.
• Convulsions of unspecified origin or occurring against the background of neurological pathologies.
• Paroxysmal tachycardia and extrasystole.
• Acute heart failure.

The drug is used with caution for severe gastritis, pancreatitis and cholecystitis.

If the instructions are violated, negative reactions from internal organs and systems may develop. Complications can arise even if all recommendations are followed.

The severity of negative reactions depends on the individual patient’s body. In some patients, the manifestations immediately disappear after stopping the course, but in many they worsen. If complications develop, it is important to visit a doctor who will prescribe symptomatic therapy to normalize the condition.

Main advantages of electrophoresis

The main advantages of the physiotherapeutic method:

• Medicines are administered in an ionized form, which is active
• If desired, you can create a high concentration of active substances in a certain place, but there will be no systemic effects and the drugs will not enter the blood
• Local therapy of the inflammatory process in the body
• The active components of drugs are not destroyed by such methods of administration
• The current carries beneficial properties - it stimulates the body’s immune response to an external pathogen, and the body exhibits humoral and reflex properties
• A prolonged effect of the drug is observed, since in this method the drug accumulates in the cells.

Contraindications for use:

• Diseases accompanied by suppuration
• Presence of acute heart failure
• Increased body temperature
• Severe form of bronchial asthma
• The presence of dermatitis or mechanical damage to the epidermis in the place where exposure to current is required
• Individual intolerance to the procedure
• History of cancer.

Electrophoresis with Eufillin

Eufillin solution for electrophoresis is used to treat various pathologies of the respiratory system, as well as the musculoskeletal system. The treatment regimen for children and adults is different, so it is important to consult your doctor first.

It is worth remembering that in case of acute diseases of the skin, the use of electrophoresis can provoke complications.

Baby

Infants older than 1 month are prescribed electrophoresis procedures for muscle hypertonicity associated with various neurological disorders. Due to the targeted effect on the affected tissue, systemic negative reactions develop quite rarely.

The procedure lasts up to 10 minutes. The specialist moistens a gauze pad, folded several times, in the Eufillin solution, and then applies it to the affected area. Electrodes are placed on the napkin, which, using electrical impulses, deliver drug particles to the affected tissues.

As a result, their regeneration occurs, spasm and pain are eliminated. Such procedures contribute to a speedy recovery. The course consists of 10 sessions with a frequency of 2-3 days.

To kid

For children, the procedure is performed for muscle damage, neurological disorders and other pathologies. The procedure is carried out according to the standard scheme once every 3 days for a month. As a result, tissue restoration occurs and blood circulation improves in the area exposed to electrical impulses.

Gauze wipes with a solution are applied to the affected area, and electrodes are placed on top. The procedure for children over 3 years old lasts 15 minutes. The course can be repeated once every 6 months.

For an adult

For adults, procedures are prescribed for osteochondrosis, arthrosis, during the recovery period after limb injuries and damage to muscles and ligaments.

The course of treatment involves 15-20 procedures, once every 3 days. The session lasts 20 minutes. It is carried out according to the standard scheme, that is, electrodes are applied to the affected areas, under which gauze wipes soaked in a medicinal solution are first placed.

During the session, low-frequency electrical impulses deliver medication particles to the affected area, which leads to rapid tissue restoration and prevents further progression of the condition.

Electrophoresis of the cervical-collar area

The safety and high efficiency of current treatment has gained great popularity. Electrophoresis with nicotinic acid on the collar zone is used for damage to the maxillofacial muscles. It normalizes damaged tissue and restores muscle function.

To carry out the procedure, a special device is used that generates current. The patient is put on a special pad that covers the shoulders, neck and shoulder blades. Filter paper moistened with a warm solution of nicotinic acid is placed under it. The temperature of the solution is brought to 38 degrees. One electrode is fixed on the pad, and the other is placed between the lower back and sacrum. Calculation of the dosage for electrophoresis with nicotinic acid on the collar area is done individually for each patient. This takes into account:

• current density;
• gasket size;
• time of the procedure;
• acid concentration;
• the ability of the drug to disintegrate into ions;
• individual characteristics of the body to the effects of electric current.

The current density depends on the size of the spacer and is inversely proportional. During the procedure, the current strength gradually increases. The course of treatment consists of 15–20 procedures. If necessary, it can be repeated after a month.

Inhalations with Eufillin

Eufillin solution for electrophoresis is often used. However, the advisability of using the drug for inhalation should be determined by a doctor.

As a rule, experts have a negative attitude towards this method, since when the vapors of the product settle on the mucous membranes, it does not enter the systemic bloodstream. But it is when the components enter the blood that the therapeutic effect occurs.

Despite doctors’ prohibitions, many adults are treated this way on their own and even treat their children. As a rule, a nebulizer is used, into which 2 ml of Eufillin solution and 3 ml of 0.9% saline solution are poured. After this, the procedure is carried out for 7 minutes.

The course consists of 5-10 sessions, which are repeated daily. Pediatricians strongly do not recommend using this method of treatment for children.

Possibility of carrying out at home

For parents who are afraid that their little treasure could become infected with common infections while performing electrophoresis in a medical institution, there is an alternative. At your request, a health care worker can pay a visit directly to your home and do everything necessary so that the little patient does not even need to leave his crib. So there is practically no reason for concern and unnecessary fuss.

Parents can be confident in the effectiveness of therapy by seeing the positive dynamics of the child after several procedures. You can purchase the device yourself. If in the future you want to carry out electrophoresis yourself, ask a medical professional to teach you how to properly use the device yourself - how to prepare medicinal solutions, how, and most importantly where, you need to apply the electrodes correctly.

A competent pediatrician will never forget to include electrophoresis in a child’s treatment plan. After all, there are actually quite a few contraindications, and such an effective method should not be underestimated in any case. In addition to the therapeutic local effect, the action of a weak electric current can increase the overall immunity and reactivity of the growing organism.

Injections

The most effective method of therapy is intravenous infusion of the solution. It should first be diluted in 0.9% saline solution. A single dosage for an adult is 3 ml. 3 ml of solution and 7 ml of sodium chloride are taken into one syringe.

Intravenous infusion is carried out slowly, it can be repeated no more than 2 times a day. For pregnant women, the dosage is selected individually in each case, which is due to the lack of data on the use of the medicine during this period.

Since this period is considered a contraindication in the official instructions, it does not describe the rules for using the solution for women during pregnancy. This means that in each case the doctor independently decides on the duration of the course and the prescribed dose.

Children under 3 months are allowed to administer no more than 60 mg of the drug per day. It is worth knowing that 1 ml of solution contains 240 mg of aminophylline. For children older than 3 months, the dose can be increased, but only the pediatrician does this based on examination data.

Patients from 1 year to 9 years are administered 5 mg of medication per 1 kg of body weight per day. Patients over 9 years of age and under 12 years of age are prescribed 6 mg of the drug per 1 kg of weight. Children over 12 years of age are given 4 to 7 mg of the drug per 1 kg of body weight per day. In each case, the dose may vary depending on the disease. The drug is administered intramuscularly very rarely.

special instructions

When using a solution for inhalation, it is important to first consult with a specialist. As a rule, doctors prescribe other drugs that are highly effective. When using electrophoresis, it is important to follow all the rules, especially when treating an infant or preschool child.

The specialist asks the patient about his well-being from time to time; if negative reactions occur, it is important to immediately stop the procedure. With long-term use of the solution and infusion of it intravenously, the doctor monitors blood pressure levels, and also examines blood and urine in order to identify kidney complications.

It is strictly forbidden to administer the drug intravenously without prior dilution with saline solution, since vascular complications may develop. With intramuscular injection, a lump or even an abscess may form in the injection area.

Indications and contraindications for use

Electrophoresis with aminophylline on the cervical spine is used in the treatment of neurological, therapeutic or surgical pathologies. Used in pediatric and traumatology practice. Ion therapy is prescribed for diseases:

How to do electrophoresis on the cervical spine correctly When it is not possible to visit a medical facility, the procedure is performed at home. To carry it out, you need to purchase a device and the prescribed medicinal substance. You should consult a physiotherapist to avoid harm to your health. But it is better to call a special team of doctors; today such a service is becoming widespread in pediatric and neurological clinics.

Drug interactions

The use of Eufillin in combination with anticoagulants and some antibiotics is not recommended. You should not use the medication simultaneously with solutions that contain fructose or glucose, as negative reactions may develop.

Anticoagulants should not be combined with Eufillin solution

It is not recommended to treat with Eufillin and administer local anesthesia to the patient . This combination can lead to complications. In each case, the decision on the combination of one or another medication is made by the doctor. If the patient takes any medication on an ongoing basis, it is worth warning the doctor about this.

It is prohibited to draw Eufillin or any other medicinal solution into a syringe. The exception is saline solution.

Shelf life of the drug

The medicine must be stored in a dark, cool and dry place. It is important to limit access to children and direct sunlight.

The maximum shelf life of the product is 2 years. It is prohibited to use the medication after this period has expired.

Such a popular medicine as Eufillin solution is used for the treatment of children and adults. The use of injections, electrophoresis and other procedures is indicated. But only as prescribed by a doctor and in the absence of contraindications.