How does Afobazol work for hypertension and in what dosage is it best to take it?

Some medications, in addition to direct effects, have side effects with positive dynamics.

This directly concerns the drug Afobazol, which, with elevated blood pressure, is able to stabilize its values.

However, the primary task of the remedy is to relieve overexertion under stress, normalize heart rate and dilate blood vessels.

It also promotes relaxation and lower blood pressure levels.

Letters from our readers

Topic: Grandma's blood pressure has returned to normal!

From: Christina ( [email protected] )

To: Administration otgipertonii.ru

Christina, Moscow

My grandmother’s hypertension is hereditary - most likely, I will have the same problems as I get older.

I accidentally found an article on the Internet that literally saved my grandmother. She was tormented by headaches and had a repeated crisis. I bought the course and monitored the correct treatment.

After 6 weeks she even started talking differently. She said that her head no longer hurts, but she still takes pills for blood pressure. I am sending a link to the article

Effect of the drug

Does afobazole increase or decrease blood pressure? This drug does not have a direct effect on the cardiovascular system.

During stressful and emotional situations, a sharp jump in blood pressure often occurs. To normalize it, take afobazole, which balances the mental state.

Afobazole can increase blood pressure during hypotension due to the fact that it tones the entire body.

When the drug affects hypertension, the pressure returns to normal due to the expansion of the walls of blood vessels. But do not forget that this tranquilizer does not have a direct effect on the heart muscle. It removes the stress response, so the production of stress factors and hormones (adrenaline, norepinephrine) stops. During stress, the adrenal glands produce adrenaline and norepinephrine, which increase muscle tone, narrow the lumen of blood vessels, blood pressure rises, the heart muscle begins to contract faster, but at the same time, blood flow to non-vital organs decreases. Therefore, for hypertension, afobazole is not the main medicine for lowering blood pressure; it only reduces and eliminates the stress reaction.

Afobazole also tones all the blood vessels of the body, normalizes blood circulation and metabolic processes.

Reduces sweating and restores moisture in the mucous membranes, has a beneficial effect on the digestive and respiratory systems, improves their functioning and prevents the development of various pathological processes.

Effect on blood pressure

You need to understand how Afobazole works—it increases or decreases blood pressure.

The primary effect of the drug is aimed at combating neurotic disorders, anxiety, chronic fatigue, and a decrease in the level of adrenaline in the blood.

This affects blood pressure values, because in most cases its increase is caused by nervous tension, doubts, shock and panic.

The body reacts to stress with the following manifestations:

• accelerated heartbeat;
• involuntary muscle contractions;
• tremor;
• insomnia;
• lack of appetite;
• dry mouth;
• hyperhidrosis.

However, if a hypertensive attack is caused by other factors, the pills will be ineffective and it will not be possible to stabilize blood pressure.

People suffering from hypotension feel the effect of Afobazole, which increases blood pressure by stimulating the central nervous system. The state of chronic fatigue, weakness, apathy disappears, and against this background a slight rise in blood pressure occurs.

For both hypertensive and hypotensive patients, the drug is prescribed exclusively in combination with other drugs.

Features pharmacological actions

The drug from the anxiolytic group calms the nervous system, but does not reduce concentration, does not impair memory, and is not addictive. The pharmacological action of Afobazole is aimed at eliminating:

• insomnia;
• feeling of fear;
• depression;
• emotional overstrain;
• apathy;
• irritability.

The drug does not disrupt the functioning of the nervous system, but reduces the symptoms of stress, which is especially dangerous for people suffering from arterial hypertension, heart and vascular diseases. Nervous stress can increase blood pressure, and Afobazol reduces it because it inhibits the reaction that occurs to stress, but it is impossible to cure hypertension by taking this drug alone.

The drug is effective when the first signs of stress occur, which manifest themselves:

• increased heart rate;
• muscle cramps;
• loss of sleep and appetite;
• strong thirst;
• abnormal sweating.

Afobazole normalizes blood pressure because it eliminates the stress that provokes its increase and reduces the number and amplitude of surges. In the treatment of arterial hypertension, the drug is used only as an addition to the main treatment regimen.

Afobazole promotes:

• weakening of seizures;
• sleep restoration;
• eliminating dizziness;
• decreased sweat production.

A person feels much better already 5 days after taking a tranquilizer. The effect continues after 2 weeks if the patient stops using it. Whether Afobazole lowers blood pressure depends on what caused its increase. The drug is unable to stop a hypertensive crisis.

Therapeutic effect

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Afobazole is a selective anti-anxiety agent, which is also called a tranquilizer or anxiolytic. Its difference from other sedatives is that it is a benzodiazepine, but it does not affect benzodiazepine receptors located in the structures of the brain.

The non-benzodiazepine structure makes Afobazol a selective drug, due to which it has an effect on the necessary brain structures, suppressing anxiety. However, this does not inhibit the natural functioning of the nervous system.

Thus, the remedy improves mood and eliminates anxiety without causing apathy, lethargy, drowsiness and lethargy. Due to the simultaneous inhibitory effect on the central nervous system, benzodiazepine anxiolytics are non-selective, and Afobazole does not have a similar effect - selective.

Moreover, in comparison with non-selective benzodiazepine tranquilizers, the drug does not relax the muscular system, does not impair attention and memory, and does not cause withdrawal syndrome. Thanks to these advantages, Afobazole is considered the safest medicine in comparison with benzodiazepines.

However, the severity of its therapeutic effect is significantly lower compared to benzodiazepines. Therefore, if the medicine turns out to be ineffective, then you will have to take more “heavy” drugs.

The main therapeutic effect of the drug is the elimination of anxiety, which reduces blood pressure caused by various fears, psychological disorders and anxiety. In addition to eliminating anxiety states, the drug stimulates the central nervous system, improves mood, increases the speed of mental processes and mental reactions.

Thus, taking Afobazole not only lowers blood pressure, but also eliminates irritability, due to which the patient’s emotional state is normalized.

Afobazol also relieves the following conditions:

• insomnia;
• tension;
• fears;
• timidity;
• lack of relaxation;
• anxiety.

Moreover, the remedy localizes such somatic and autonomic manifestations of anxiety as:

1. dizziness;
2. muscle twitching;
3. sweating;
4. increased sensitivity;
5. dry mouth;
6. vascular, cardiac and gastrointestinal disorders.

In addition to the fact that Afobazole lowers blood pressure, it improves concentration and memory. However, this effect is achieved after 5-7 days from the start of taking the medicine, and the full therapeutic effect is observed at the end of the fourth week of therapy. As a rule, after discontinuation of the medication, the therapeutic effect lasts for 7-14 days.

Afobazole is the right choice for patients with asthenic traits (vulnerability, too emotional reaction to stress, anxious suspiciousness, emotional instability, etc.).

It is worth noting that the medicine lowers blood pressure only if this condition is caused by strong feelings or anxiety. In such a situation, the drug will have a calming effect, due to which blood pressure levels normalize. But there is no point in taking Afobazole for hypotension, since it does not increase blood pressure.

The advantage of Afobazole is that it is non-toxic and quickly enters the bloodstream from the intestines, entering the brain cells.

The drug is excreted along with feces and urine, and it does not accumulate in the body even after long-term use.

Who is it prescribed to?

The drug, which is easily tolerated, is excreted from the body in urine and feces in a short time, is prescribed for neurasthenia and prolonged stress. Afobazole is prescribed for low blood pressure, which is observed in vegetative-vascular dystonia.

Indications for use of the drug are:

• severe fatigue;
• anxiety disorders;
• prolonged insomnia;
• adaptation disorder;
• neurasthenia.

The product is suitable for women who suffer from premenstrual syndrome. Afobazole reduces the stress that occurs when a person quits smoking or stops drinking alcohol. It is prescribed in combination with other drugs for therapy:

• lupus erythematosus;
• dermatitis;
• bronchial asthma;
• hypertension and ischemia;
• arrhythmias and tachycardia.

For vegetative-vascular dystonia, the medicine can increase blood pressure and stimulate the functioning of the nervous system. The drug is effective for low vitality, as it eliminates weakness and improves mood.

Afobazol helps with asthenia:

1. Eliminate suspiciousness.
2. Cope with constant fatigue.
3. Get rid of headaches.

During menopause, the drug alleviates the woman’s condition; it also relieves the symptoms that appear with irritable bowel syndrome.

Side effects

This remedy can also cause some negative effects when taken:

• weakness, apathy, lack of coordination.
• headache attacks.
• allergy.
• nausea, diarrhea.

Afobazole is non-toxic and has a remarkable property - it is immediately eliminated from the body without accumulating in it, so an overdose is very unlikely, and all negative symptoms stop on their own and do not require discontinuation of therapy.

If allergic reactions are serious (Quincke's edema), you should immediately stop taking it and seek qualified help and advice from a hospital.

Contraindications

Despite the completely physiological and rather mild effect of Afobazole, it has certain contraindications and side effects, although, unlike the vast majority of other drugs, they are very few. Contraindications (absolute and relative) to the use of Afobazole are the following conditions:

1. Allergy to components, and in view of this, the drug should never be taken by patients with genetically determined galactose intolerance, lactase enzyme deficiency, congenital or idiopathic glucose-galactose malabsorption.
2. Afobazole should not be taken by persons under the age of 18, since the effect on this group of people has not yet been fully studied by pharmacologists.

Hypertension

Features of use

Afobazol, prescribed for low blood pressure, does not cause side effects associated with an even greater decrease in blood pressure.

With high blood pressure, the medication has no effect on blood pressure. A decrease in pressure occurs in the process of the positive effect of the drug on psycho-vegetative manifestations.

Afobazole does not interact with antihypertensive substances.

However, concomitant use will increase the anticonvulsant effect of carbamazepine. And potentiate the anxiolytic effect of diazepam.

During therapy with Afobazole, unlike some other tranquilizers, the psychomotor functions of the human body do not decrease. Consequently, working with high-precision tools and driving vehicles is not prohibited.

For whom the drug is contraindicated

Like other medicinal medications, Afobazole has its own contraindications, in which taking tablets is strictly prohibited in order to avoid deterioration of health. Contraindications include:

1. Age under 18 years.
2. Galactosemia.
3. Lactose deficiency.
4. The period of bearing a baby.
5. Breastfeeding.
6. Allergic manifestations to the constituent components of the drug.
7. Severe brain pathologies.

All contraindications must be taken into account by the doctor when prescribing the drug to a patient, otherwise it can lead to serious health problems.

Possible adverse reactions and overdose

Numerous positive reviews indicate that Afobazole is well tolerated. It does not have any negative impact on well-being, moreover, it improves it and stimulates an overall positive attitude.

Very rarely, but still there are individual reactions to the components of the drug:

• skin allergies;
• nausea with vomiting;
• bowel dysfunction (diarrhea).

Sometimes headaches and allergic manifestations occur

Unpleasant symptoms usually do not require discontinuation of the medication and go away on their own. In some cases, there is an increase in libido against the background of emotional relaxation, which can hardly be called a negative reaction.

The drug does not tend to accumulate in human organs and systems, so an overdose is unlikely. It is possible only in case of gross violation of the treatment regimen and an uncontrolled increase in the daily dose several times.

In this case, a sedative effect may occur, expressed in:

• dizziness;
• drowsiness;
• weaknesses.

Returning to an adequate therapeutic regimen gradually removes all unpleasant symptoms. In severe cases, you will need subcutaneous administration of an antidote in a hospital setting - sodium caffeine benzoate (20 percent solution) 1 ml 3 times a day. It raises the overall tone of the body and blood pressure.

Contraindications and side effects

Afobazole is not prescribed for children and adolescents, nursing mothers and pregnant women. Do not take the drug if you have hypersensitivity to the active ingredient. For neurocirculatory dystonia, a tranquilizer is not prescribed when the patient has very low blood pressure. It is not recommended to use the product if you are lactose intolerant. With this disorder, the human body does not process milk sugar.

The drug does not accumulate in the blood and rarely causes unpleasant effects such as:

• headache;
• diarrhea and nausea;
• skin rashes.

With prolonged use and increasing the dosage several times, weakness appears. A person complains that he constantly wants to sleep. Usually, side effects go away on their own, and only if the patient’s condition is severe, sodium caffeine benzoate is administered.

Application

Afobazole is available in tablet form and is taken orally without chewing. During the first stage of use, a short-term deterioration of the condition may be observed, stopping by the end of the first week of use.

Drink one or two tablets with water for vegetative-vascular dystonia, for minor disturbances in the emotional state. If the diseases are serious, then dose up to 60 mg. In order to simply reduce high blood pressure, it is enough to take one tablet three times a day.

The active components of the drug begin to influence body processes after five days of use, manifesting themselves in the form of:

• reducing sweat formation;
• improving mood and concentration;
• normalization of oral humidity;
• disappearance of anxiety.

The course of treatment lasts 1–3 months, depending on the disease. There is no addiction to the drug. After the course, the result lasts for a week. The dosage and period of treatment are prescribed by the attending physician; you should not self-medicate or change dosages.

To stabilize the positive result of treatment, the drug must be taken as a course and not episodically

Some people, for various reasons, do not react entirely correctly to stressful situations; their central nervous system and internal nervous system malfunction. Accordingly, due to the above disorders, a large number of autonomic disorders manifest, in particular, an increase in blood pressure and heart rate. So Afobazol is used in these situations, mainly due to its following features:

• The drug affects the psychological and cognitive functions of the human body. It significantly reduces the incidence of dangerous autonomic disorders, such as dry mouth, hyperhidrosis, and orthostatic dizziness.
• The increased effectiveness of Afobazole occurs in people with the asthenic type of NS, that is, those who are significantly prone to depression, stress, and overly expressed emotional reactions.
• The use of the drug is especially indicated in cases of increased suspiciousness, vulnerability, lack of self-confidence and strength, as well as a tendency to violent psycho-emotional manifestations.

Taking into account the above features, practicing doctors recommend this medicine for the following pathological conditions:

• neurasthenia, systematic anxiety and preoccupation that are not amenable to any physiological internal control;
• premenstrual syndrome and algodismenorrhea;
• unreasonable, unmotivated fears and sleep disturbances;
• psychosomatic diseases (increased heart rate and blood pressure, IBS, hyperhidrosis, various manifestations of VSD);
• NDC;
• withdrawal syndrome caused, among other things, by nicotine addiction;
• as part of complex therapy of oncological and dermatological nosologies;
• in the event that there are cognitive impairments - difficulties in remembering, concentrating;
• excessive anxiety for various reasons.

Rules of application

It is strongly recommended to take the tablets at full dosage immediately, so there is no need to increase it gradually. After all, the drug has a fairly mild effect and the body does not need to waste time getting used to this drug.

In addition, it is quite acceptable to stop taking the drug immediately and quickly. This feature is explained by the fact that Afobazol does not cause iatrogenic dependence, and for these reasons there is not even the slightest sign of withdrawal syndrome, which is very difficult to tolerate by almost all patients who were on drugs that have a direct effect on the central nervous system and internal nervous system. It is not difficult to guess that it is precisely because of this that the drug is an accessible and simple remedy, indicated for almost everyone.

These pills are often safely taken even in trial mode. For example, they can be safely used for 4-5 weeks for the expected therapeutic effect to appear, and after that only evaluate how suitable this drug is for systematic use.

If the clinical effectiveness of the pharmaceutical is acceptable, then it is permissible not to stop taking it, but otherwise the patient has the right to change the drug on the same day. However, when replacing drugs with other anti-anxiety pills, it is imperative to remember that a clinically significant effect from Afobazole after interrupting its use takes another 7-14 days.

Accordingly, in order to prevent adverse reactions, the use of other drugs can be started no earlier than 2 weeks after the preliminary withdrawal of Afobazole. And repeated use after using other tranquilizers is indicated strictly after 7-10 days.

The tablets are consumed only after meals, without chewing or crushing them, and washed down with a significant amount of boiled, purified water. To lower blood pressure by inhibiting the activity of the sympathoadrenal system, if there are no contraindications to this, Afobazole is consumed 10 mg (2 tablets of 5 mg, 1 tablet of 10 mg) 3 days a day, at equivalent time intervals. Accordingly, the dose for a single dose will be 10 mg, and the daily dose will be 30 mg.

Afobazole reduces blood pressure provoked by stressful conditions after regular, systematic use (its prolongation is 2-4 weeks). Then the course of treatment must be interrupted - for about 4 weeks, and then continued again according to the above scheme.

If necessary, and only under tireless medical monitoring of the condition of the vital systems, the dosage is increased to 20 mg three times a day, and the continuation of continuous treatment is extended up to 90 days, but the need for this kind of thing arises extremely rarely.

According to the data presented in the annotation attached to Afobazol, when relieving hangover syndrome, the strongly recommended dosage is a multiple of 5-10 mg twice a day. The course of therapy depends on the prescription of the attending physician, but is usually prolonged for about 2-4 weeks. If the need arises, of course, the course can be extended. However, before resuming treatment, it is strongly recommended to take a break of approximately 3-4 weeks.

It is important to emphasize one more feature - it is that Afobazole realizes its effect gradually. It slowly accumulates, cumulates and begins to be expressed only after a certain time after the start of treatment, usually after a week. Therefore, in that situation, if you started taking it and did not notice any particularly significant improvements in the first days, then this does not mean that the pharmaceutical does not work. It's definitely worth waiting a little longer.

One of the important advantages of this drug is that it does not interact in any way with ethanol. However, it is important to understand that during the course of therapy, drinking any alcoholic beverages is extremely undesirable, since they neutralize the therapeutic effect to a certain extent.

Interactions with other drugs are minimal. When combined with Diazepam, it significantly potentiates its anxiolytic effect, and also potentiates, but to a lesser extent, the anticonvulsant effect of Carbamazepine. Combined use with antidepressants is strictly prohibited.

At the same time, it is necessary to point out that in case of pathologies of the heart and blood vessels, Afobazole and alcohol are a completely incompatible combination. This incompatibility lies in the rather negative effect of ethanol on the heart, and alcohol blocks the effect of Afobazole on it.

Instructions for use

After consultation with a specialist, you can begin treatment immediately. The prescribed dosage can be administered immediately rather than gradually. Cancellation of therapy does not require a gradual dose reduction.

If before starting treatment the patient was undergoing therapy based on similar sedative medications, it is recommended to leave an interval between courses of at least 10 days.

Swallow the tablet whole with plenty of water. It is advisable to take the medicine after meals.

In case of minor disruptions in the functioning of the central nervous system, you should take 1 tablet in 2 to 3 doses. In this case, the maximum permissible dose of the active component is no more than 30 mg per 24 hours.

If the patient has a severe neuralgic condition, 2 tablets are prescribed in 3 doses. In this case, the maximum allowable dosage will be 60 mg.

In the instructions for the use of Afobazole for high blood pressure due to psychological experiences, a daily dose of 30 mg, divided into 3 doses, is recommended to reduce its indicators.

The course of therapy must be long-term, otherwise taking the drug will not give any results. The active substance is activated in the body no earlier than after 5–6 days.

The minimum duration of therapy is 28 - 30 days. The maximum duration of one course is 90 – 95 days. After stopping the medication, the patient will feel its effect for 8 to 10 days, and he will not feel any negative consequences due to the end of the course of treatment.

It is strictly prohibited to refuse the drug or change the dosage yourself. The duration of treatment and dose are selected individually for the patient by the doctor.

Side effects from taking the medication and symptoms of overdose

Afobazole tablets can cause side effects, for which a person should be prepared. These include:

1. Dermatitis.
2. Itching developing on the body.
3. Frequent sneezing.
4. Diarrhea.
5. Hives.
6. Nausea progressing to vomiting.
7. Angiitis.
8. Chronic runny nose.

If these side effects occur, you should not stop therapy, but you should inform your doctor about them, especially if the side effects do not go away within several days. In this case, the specialist will reconsider the dose and frequency of taking the medicine.

An overdose of Afobazole is often observed when taking a large dose of the medicine, which a person drinks at one time. Therefore, the doctor should prescribe the dose of the medicine, based on the type and degree of pathology, as well as the general state of health.

If the patient is prescribed medication at a dose of no more than 60 mg per day, he will not develop an overdose, since the active substances of Afobazole do not accumulate in the tissues of the body.

To prevent an overdose of the drug, which is manifested by drowsiness and sedation without relaxation of the muscular system, the patient needs to inject 1 ml of a 20% solution of caffeine sodium benzoate into the body. This should be done 2-3 times a day and always at regular intervals.

Use by the elderly

Since the drug has a gentle effect, it is easily tolerated by older people.

The list of possible side effects is quite small, so doctors often prescribe this drug to older people. In old age, it is extremely important that there is no addiction, which is what distinguishes this medication from some analogues that are similar in their effect.

Afobazole effectively reduces blood pressure in people who are weakened and suffer from hypertension.

Interaction with other drugs

As a rule, a complex therapeutic regimen for anxiety should include several medications that will complement each other’s action, leading to an effective result. A good effect of the drug is observed when taken with Diazepam (increases the anxiolytic effect) and Carbamazepine (increases the anticonvulsant effect). Does not interact with ethanol.

Many medications can be combined with taking Afobazole to achieve a quick therapeutic effect, but only a doctor should do this. Incorrect combination of several psychotropic drugs along with blood pressure pills can cause unpredictable consequences. It is also better to avoid independently combining different groups of antidepressants.

Analogs

Drugs that are similar in their action, but have other active ingredients include:

• Phenazepam;
• Divaza;
• Anvifen;
• Adaptol;
• Phenorelaxan;
• Noofen;
• Mebicar;
• Grandaxin;
• Tranquilar;
• Fesipam;
• Tenoten.

Fabomotizol and Neurofazol, which are used for droppers, are similar in composition. Before replacing Afobazole with another drug, you should definitely consult a specialist, since various components in other drugs can have an unpredictable effect on the body.

Afobazole's analogs

If a patient is prohibited from using Afobazol for health reasons, the doctor may prescribe medications similar in composition and principle of action. The best and most effective analogues are:

Each of these medications must be prescribed to the patient by a doctor, as they have an individual list of contraindications and side effects.

A well-designed treatment regimen allows a hypertensive patient to quickly restore the level of pressure that was disturbed due to an anxious state, as well as normalize the functioning of the entire body by restoring the nervous system.

Price and analogues

You can buy Afobazole at any pharmacy chain if you have a prescription from a doctor. As for the price, it varies depending on how many tablets are in the pack, and ranges from 150 to 600 rubles.

There are no similar drugs in terms of effects and components, but there are drugs that have similar properties:

• Adaptol;
• Divaza;
• Tenoten;
• Persen;
• Fanazepam;
• Novopassit.

Considering all of the above, we can conclude that Afobazol is able to normalize blood pressure, both by increasing and decreasing it. However, the effect will only occur if blood pressure levels change due to stress. Under any other circumstances, it will not be possible to normalize the tonometer values ​​using this medicine.

Reviews about the use of the medication

Linda, 32 years old: This time it was a difficult start to the year with active blockages at work, family troubles, and money problems. Everything accumulated like a snowball, and as a result, even the VSD worsened with such force that I did not have the strength to get out of bed. I’m glad that I started taking Afobazol on time, because headaches and pressure surges due to nervousness were already finishing off my body. After taking the drug I felt much lighter and calmer.

Anatoly, 41 years old: A very convenient and effective product that can probably be found in every pharmacy. During periods of life crisis, Afobazol more than once saved me from anxiety, relieved irritability and aggression. The desire to yell and swear at everyone and everyone faded away.

Inna, 35 years old: I let myself go to such a state that I couldn’t sleep peacefully at night, and during the day I would rush at everyone like a dog, get irritated for no reason, be capricious, and any person could become a source of my uncontrolled aggression. My blood pressure even increased, and in this state it doesn’t take long to develop hypertension. Therefore, I started my Monday by taking Afobazole. As the therapist said, this drug will help improve my mood and relieve irritability. The prescribed course has not yet ended, but the first changes for the better can definitely be felt.

Stress and high blood pressure

The modern rhythm of life forces us to find ourselves in stressful situations more often than we would like. The mechanism of influence of stress factors on the body leads to increased heart rate and, as a result, increased blood pressure. Why is this happening?

When stressful factors occur, the human body begins to actively defend itself by producing the following hormones:

• adrenalin;
• norepinephrine;
• cortisol

"Afobazole" can be used for high blood pressure, but only if it is provoked by strong feelings.
Under the influence of the above hormones on the body, the heart begins to beat faster, the blood vessels narrow, blood circulates faster throughout the body, which leads to an increase in blood pressure, and this threatens each of us with a dangerous disease - hypertension.

This disease is characterized by high blood pressure, which is manifested by frequent headaches, heart pain, and blurred vision. Not only older people, but also young people are at risk.

In addition to high blood pressure, stress in people prone to hypertension may be accompanied by:

• insomnia;
• timidity;
• increased sweating;
• dry mouth;
• dizziness;
• involuntary muscle contraction;
• gastrointestinal disorders.

The drug Afobazol will help relieve all these symptoms of high blood pressure.

Indications and contraindications

The wide spectrum of action allows the drug to be prescribed for many physiological and psychological pathologies that are accompanied by somatic disorders.

In addition to eliminating anxiety, the drug stimulates the central nervous system, improves mood, increases the speed of mental processes and mental reactions

Direct indications for the use of tablets are:

• anxiety disorders;
• neurasthenia;
• withdrawal syndrome due to alcoholism;
• withdrawal reaction during the period of quitting smoking;
• vegetative-vascular dystonia;
• adjustment disorder;
• premenstrual syndrome in women;
• chronic insomnia;
• emotional instability;
• surges in blood pressure due to stress;
• asthenic character (vulnerability, imaginaryness).

Any disturbances of an emotional and psychological nature can be successfully relieved with the help of Afobazole.

In addition, it is often prescribed in the complex therapy of internal diseases when they are of a psychosomatic nature, namely:

• dermatitis;
• hypertension;

Studies have proven that this drug is the best choice for people with heart problems that cause their emotional state to fluctuate.

• bronchial asthma;
• arrhythmias;
• irritable bowel syndrome;
• cardiac ischemia.

With panic fear against the background of serious illnesses, especially cancer, this treatment also helps. The tablets relieve stress and depression, improve sleep and the general condition of a person.

Most tranquilizers are intended for the treatment of adult patients. This remedy is no exception, which is strictly prohibited for children and adolescents.

Strict contraindications are also:

• history of allergic reactions to components;
• pregnancy and lactation;
• lactose intolerance;
• severe brain pathologies.

Indications for use

This drug has an anti-stress effect and affects brain neurons, promoting their regeneration.

The drug is prescribed for the following disorders:

• if the patient is susceptible to nervous breakdowns, often finds himself in a stressful environment, experiences chronic fatigue and impotence;
• women suffering from the negative effects of PMS, as well as experiencing severe pain during menstruation;
• for insomnia, anxiety;
• increased heart rate;
• hypertension (especially when the disease is at stage 1);
• excessive sweating;
• VSD;
• neurocircular dystonia, causing disturbances in blood flow in the body;
• with complete cessation of drinking alcohol or smoking;
• in case of impaired cerebral circulation, inability to concentrate on a specific issue, poor memory;

Afobazole is recommended if the diagnosis makes the patient nervous - oncology, bronchial asthma, ischemic heart disease, dermatitis of various etiologies, irritable bowel syndrome, systemic lupus erythematosus.

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Release form and composition of the drug

Afobazole is a drug from the group of mild tranquilizers with an anti-anxiety effect. Produced by a Russian pharmaceutical company in the form of tablets for oral administration. They look white, small in size, without a shell. They have no foreign odors or taste. They are packaged in contour packages (blisters) of 10, 20 and 25 pieces, as well as in polymer jars of 30, 50 and 100 pieces. Stored in a dark, dry place for 2 years. Available in pharmacies without a prescription.

Afobazol is an effective remedy that relieves anxiety, due to which blood pressure levels are normalized.

The drug is a monocomponent, with one active ingredient – ​​morpholinoethylthioethoxybenzimidazole dihydrochloride (fabomotizole hydrochloride). Its tablets contain 5 mg or 10 mg, depending on the dosage.

Added as auxiliary ingredients:

• cellulose;
• magnesium stearate;
• potato starch;
• povidone;
• lactose.

Afobazole is a relatively new drug that has proven itself as first aid for anxiety and depression.

Composition and appearance

The drug, which has recently been produced by a pharmaceutical company from Russia, has gained popularity as one of the best remedies that quickly relieves an attack of depression. Afobazol is produced in the form of white tablets that have neither taste nor odor. In pharmacies, the medicine is sold in blisters No. 25, 10 or in small polymer jars of 50, 100 and 30 pieces.

The active component of the drug is fabomotizole hydrochloride; the composition contains additional substances in the form of:

• lactose;
• starch;
• cellulose;
• magnesium stearate;
• milk sugar.

The drug can reduce high blood pressure if its increase is associated with stress, as it relieves nervous tension and anxiety. Tablets are available with active ingredient contents of 10 and 5 mg.

Combination with other substances and medications

To avoid adverse consequences, the attending physician himself prescribes all necessary and additional medications.

Afobazole can be used with carbamazepine and diazepam, but in certain dosages.

Alcohol reduces the effectiveness of the drug, but despite this, hangover and anxiety are quickly eliminated. All this happens due to the fact that:

• starch prevents ethyl alcohol from being absorbed;
• milk sugar fights lethargy and apathy;
• Povidone, together with cellulose, promotes the rapid elimination of toxins;
• stearic acid relieves irritation;
• for withdrawal symptoms, take two tablets per day.

The effect of soothing herbal infusions and antidepressants is enhanced.

Does it increase or decrease blood pressure?

A drug called Afobazole is not a direct drug for normalizing blood pressure. It only indirectly affects its performance. If there is a jump in blood pressure due to stress or strong feelings, then with the help of tablets you can achieve normalization of the emotional state, and with it a decrease or increase in blood pressure readings.

Many people are interested in whether Afobazol is able to normalize blood pressure if a hypertensive attack occurs. This question can be answered with confidence - under such circumstances, pills will not help. The picture is exactly the same in the situation with hypotension; the medicine can only slightly increase the pressure by toning the body.

Taking medications and alcohol

The drug combines well with Diazepam and is used in combination with Carbamazepine. Only a doctor should select these drugs; the wrong combination is fraught with serious consequences.

Afobazole does not react with alcohol, but while drinking alcohol, the effectiveness of the tranquilizer is noticeably reduced. For hangover syndrome, it relieves symptoms and eliminates anxiety:

1. Cellulose and povidone present in the product help remove toxins.
2. Starch prevents the absorption of ethyl alcohol residues into the blood.
3. Magnesium stearate soothes and relieves irritation.
4. Lactose fights apathy and lethargy.
5. For post-alcohol syndrome, take 2 tablets of the drug per day.

Thanks to Afobazole, blood pressure is reduced, the patient’s emotional state is normalized, and memory is improved. Immediately after taking the pill, a person can drive and operate equipment, since the active component does not affect concentration.

Afobazole enhances the effect of sedative herbal infusions and is combined with antidepressants.

Afobazole for hypertension (high blood pressure) and vegetative-vascular dystonia (VSD)

Despite the fact that Afobazole does not have the properties of lowering or increasing blood pressure , it is successfully used in complex therapy for hypertension and vegetative-vascular dystonia. This effectiveness of the drug is directly related to its positive effect on anxiety.

Most often, our body reacts to stress by increasing blood pressure. This is due to the production of adrenaline, which provides specific protection in stressful situations, maximizing the performance of our body and brain. Adrenaline release is the body's response to an emotional stimulus.

However, with an increase in the activity of the body, blood pressure increases, and in order to normalize it, the heart must work with overload, and therefore various disturbances in its activity may occur.

In order to prevent the consequences of a stressful situation or help the body resist its negative effects, doctors prescribe taking Afobazole for blood pressure. More precisely, a decrease in blood pressure is a positive side effect of the drug, which occurs when the patient’s anxiety and feeling of restlessness are reduced.

VSD also requires complex treatment. To relieve the symptoms of psychoneurological disorders, in particular convulsive states and dizziness, as well as to stabilize the general emotional state of the patient with vegetative-vascular dystonia, Afobazol is prescribed in a combined therapy regimen with other drugs.

As we found out, the drug does not have a direct effect on blood pressure. However, with vegetative-vascular dystonia and hypertension, the positive effect of Afobazole on blood pressure is manifested through the normalization of the patient’s psycho-emotional state. This property plays a vital role in the use of Afobazole for the treatment of generalized anxiety disorders.

With a decrease in the symptoms of stress and anxiety, blood pressure decreases to normal, as well as an improvement in the patient’s general condition and an increase in physical and mental performance.